Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,952 recruiting studies in this area right now.
By phase
- Not applicable9,355
- Phase 2761
- Phase 1558
- Phase 3514
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke798
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis328
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke138
- Sarcopenia134
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management116
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California661
- Massachusetts305
- New York295
- Florida272
- Texas266
- Maryland248
- Alabama207
- Arizona206
- Illinois181
- Pennsylvania177
Recruiting studies11,952 total
- NCT06833489Recruiting
Using genetic testing to find answers for rare muscle diseases
This study looks at leftover muscle tissue from people who have had genetic testing for rare muscle diseases but didn't get a clear diagnosis. The goal is to use newer genetic analysis to find the cause of their disease.
MarseilleAges Any age - NCT06832267Recruiting
RMTT chemo for newly diagnosed PCNS lymphoma
This trial tests a combination of four chemotherapy drugs (Rituximab, Methotrexate, Temozolomide, and Thiotepa) as the first treatment for people newly diagnosed with primary central nervous system diffuse large B-cell lymphoma. It aims to see if this regimen is safe and effective for patients who have not had any prior systemic therapy.
Hangzhou, ZhejiangAges 18–75 - NCT06832839Recruiting
Cognitive impairment in moyamoya disease study
This study looks at why some people with moyamoya disease have trouble with thinking and memory. It may help find better ways to understand and treat these problems.
Beijing, ChinaAges 18–60 - NCT02912897RecruitingPhase 1
EBV T-cell treatment for early multiple sclerosis-like symptoms
This early-phase study tests whether a patient’s own immune cells (made to target a common virus called EBV) are safe and practical for people who have their first episode that strongly suggests multiple sclerosis. If it works well, it could offer a new way to treat early disease—but the main goal now is safety and feasibility.
NantesAges 18–45 - NCT05492175Recruiting
Robotic therapy with games for arm recovery after stroke
This study compares two styles of robotic training (focused more on the shoulder/upper arm versus the hand/wrist) plus movement games to improve arm function after a first stroke. It may help people regain more useful arm and hand movement through guided, repeatable practice.
TaichungAges 20–80 - NCT05677243Recruiting
Observational study of radiosurgery for trigeminal neuralgia pain
This study follows people with trigeminal neuralgia to see how radiosurgery treatment affects their facial pain. It may help doctors better understand who benefits when medicines do not control the pain enough.
MonacoAges 18 years+ - NCT05885529Recruiting
Blood and CT tests after a concussion to track brain injury
This study checks whether two blood proteins (GFAP and UCH-L1) can help identify which brain spots are linked to a significant head injury after a concussion. You may be able to help by providing a blood sample and getting a CT scan as part of usual care, so doctors can better sort out injury risk.
AngersAges 18 years+ - NCT06541041Recruiting
Nerve transfer with electrical stimulation for hand function after spinal injury
This trial tests a surgery that moves nerves (nerve transfers) plus gentle electrical stimulation to help people with spinal cord injury regain hand movement. It may be a good fit if you have a C6 or C7 injury and haven't had hand surgery before.
Palo Alto, CaliforniaAges 18–65 - NCT06740188RecruitingPhase 4
Trazodone for depression and insomnia with poor sleep quality
This trial tests if trazodone, a medication, can improve deep sleep in people who have both depression and insomnia. It aims to find a treatment that helps with both conditions at once.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT07385911Recruiting
Smell after skull base surgery: cautery vs scalpel
This trial compares how using a cautery tool versus a scalpel during skull base surgery affects a person's sense of smell. It aims to see which method better preserves smell function.
Jodhpur, RajasthanAges 18 years+ - NCT07380737Recruiting
Walking Tall app for home exercise in Parkinson's
This study tests a smartphone app called Walking Tall that helps people with Parkinson's disease do walking exercises at home. It's looking for people who can walk on their own and are already in a specific rehab program.
Tel AvivAges 40–85 - NCT07388043Recruiting
AP-Brain for memory in older adults with memory concerns
This trial tests a supplement called AP-Brain to see if it helps with memory and thinking in healthy middle-aged and older adults who notice memory problems. You would take different doses of the supplement or a placebo for several weeks and complete memory tests.
London, OntarioAges 40–79 - NCT07387094RecruitingPhase 3
A study of XW003 for obesity with sleep apnea (no CPAP)
This trial tests an investigational weekly injection called XW003 for weight loss in people who have obesity and moderate-to-severe sleep apnea but do not use a CPAP machine. It aims to see if the drug can help with weight loss and improve sleep apnea without the need for a breathing machine.
Beijing, Beijing MunicipalityAges 18–75 - NCT07380490Recruiting
Comparing two heart-opening closure devices after a stroke or TIA
This trial compares two devices that close a small opening in the heart called a PFO, which can let clots pass and cause strokes. If you've had a stroke or mini-stroke with no other cause, this study might help prevent future ones.
Bad Oeynhausen, North Rhine-Westphalia (Nordrhein-Westfalen)Ages 18–65 - NCT07380412Recruiting
Supplement study for ADHD med side effects
This trial tests if a dietary supplement can help reduce common side effects of stimulant medications for ADHD, like trouble sleeping or feeling irritable. If you take a stable dose of ADHD medication and are dealing with these issues, you may be able to join.
Las Vegas, NevadaAges 18–55 - NCT07382440Recruiting
Study of a Parkinson's treatment given under the skin
This study looks at how well a treatment called foslevodopa/foscarbidopa works for people with advanced Parkinson's disease. It is given as a shot under the skin (subcutaneous) and is already being used in clinics. The study will follow people who are already starting this treatment as part of their regular care.
Bonheiden, AntwerpenAges 18 years+ - NCT07388992Recruiting
Walking patterns in people with MS
This study uses special sensors to compare walking patterns in people with multiple sclerosis (MS) and healthy volunteers. The goal is to see how MS affects walking over time, which may lead to better ways to track and treat movement problems.
LilleAges 18–65 - NCT07388576Recruiting
AP-Brain supplement for attention in healthy young adults
This trial tests a supplement called AP-Brain to see if it helps with attention and focus in healthy young adults (ages 18–39) who feel they have attention problems. It compares different doses to find the safest and most effective one.
London, OntarioAges 18–39 - NCT06835426Recruiting
Imaging removed tissue during cancer surgery
This study tests a high-resolution PET-CT scanner that takes pictures of tissue removed during surgery to help doctors see if all the cancer has been removed. You might qualify if you are having surgery for a range of cancers including breast, prostate, thyroid, skin, gastrointestinal, or brain tumors.
Ghent, Oost VlaanderenAges 18 years+ - NCT06833645Recruiting
PET scans to spot early Alzheimer's changes
This trial uses special PET scans to see amyloid and tau proteins in the brain, which are linked to Alzheimer's. It aims to find these changes early, in people with mild memory problems or early-stage Alzheimer's.
Chengdu, SichuanAges 18 years+ - NCT06833710Recruiting
Ear acupressure for better sleep in nurses
This study tests if applying small acupressure stickers on specific ear points can improve sleep quality for nurses. It may help if you have poor sleep and want a simple, drug-free option.
TaipeiAges 18–65 - NCT02057783Recruiting
Exercise program to lower blood pressure in sleep apnea
This trial tests whether a supervised physical activity program can help lower blood pressure in people with obstructive sleep apnea and resistant high blood pressure. It may help you control blood pressure when it has not improved despite multiple medications.
QuébecAges 18–80 - NCT07380269Recruiting
Long-term study of cochlear implant outcomes
This study follows people who get a cochlear implant – a device that helps restore hearing. It tracks how well you hear over time and checks for any long-term benefits or problems.
ShanghaiAges Any age - NCT07385027Recruiting
Brain wave study in romantic couples
This trial uses EEG to study brain activity in romantic couples. It tests how partners' brains connect in different settings and includes a brief pain stimulus on the leg.
Charlestown, MassachusettsAges 20–60
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,952 recruiting neurology studies from the U.S. registry right now, out of 18,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.