Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT05320263Recruiting
Thrombectomy timing: aspiration tube vs stent for basilar stroke
This trial compares two ways to remove a blockage in the brain’s basilar artery: suction (aspiration) versus a retriever stent. It may help doctors learn which approach works better for restoring blood flow in acute stroke patients.
BordeauxAges 18 years+ - NCT05320822Recruiting
Rehab program study for recent mild concussion
This study tests a practical rehabilitation approach for people with a recent mild concussion (mTBI). You may be able to join if your injury happened recently and your symptoms match a “mild” concussion pattern on your medical record.
Fort Liberty, North CarolinaAges 18–99 - NCT05321459Recruiting
Testing outcome prediction in comatose patients after cardiac arrest
This study looks at tests that may help predict outcomes in people who remain in a coma 3 to 7 days after surviving a cardiac arrest. It may help doctors better estimate recovery and guide care decisions.
BobignyAges 18 years+ - NCT05321355Recruiting
Sleep disorder patient registry for narcolepsy and other conditions
This is a research registry that collects information from people with narcolepsy and other neurological sleep disorders. It may help doctors better understand sleep problems and improve future care.
Mainz, Rhineland-PalatinateAges 18–120 - NCT05322837Recruiting
Tracking arm nerve and strength recovery after first stroke
This study follows how stroke survivors’ arm feeling (sensory) and movement (motor) recover over time. It may help clinicians better understand recovery patterns in Asian patients and improve rehabilitation support.
SingaporeAges 21–90 - NCT05322824Recruiting
Study for adults with narrowed brain or neck arteries
This study enrolls people age 40 or older who have at least 50% narrowing in one brain or neck (carotid) artery. It collects clinical information to better understand this condition and how patients are doing over time.
Hangzhou, ZhejiangAges 40 years+ - NCT05322343Recruiting
Study biobank and brain health in people age 55–80
This study collects blood samples to build a biobank and learn how brain health changes with age. Some participants may also do an MRI scan to better understand brain changes and immune response.
Bordeaux, BordeauxAges 55–80 - NCT05323916Recruiting
Intensive rehab program after a first stroke
This trial tests whether an intensive, day-long rehabilitation program can improve recovery after a first ischemic stroke. It focuses on people with mild to moderate disability who can safely handle several hours of therapy each day.
PragueAges 18–85 - NCT05324475Recruiting
Nutritional supplement to support immunity and energy in older adults
This trial tests whether a safe nutrition supplement can help older adults with malnutrition maintain immune function and energy (mitochondrial function). It may support recovery during rehabilitation, but you must meet specific nutrition and health criteria.
Lausanne, SwitzerlandAges 75 years+ - NCT05324748RecruitingPhase 3
Repeated nerve-block shots for chronic cluster headache
This Phase 3 trial tests whether repeated injections can reduce attacks of chronic cluster headache. It may help people who have frequent, consistent attacks and can track them closely during the study.
LeidenAges 18–70 - NCT05326750Recruiting
Brain stimulation to help diagnose and manage memory conditions
This trial studies a non-invasive brain-stimulation approach to help doctors assess and manage certain brain-related conditions. You might benefit by contributing to better diagnostic tools and treatment planning for memory and thinking problems.
KuopioAges 18 years+ - NCT05326451Recruiting
At-home brain stimulation for Huntington’s behavior and thinking symptoms
This trial tests an at-home, noninvasive brain stimulation treatment to help with behavioral and cognitive (thinking) symptoms in people with Huntington’s disease. You and a caregiver work together during sessions and questionnaires to see if symptoms improve and stay stable.
Houston, TexasAges 18–80 - NCT05326932Recruiting
Extended-Time Thrombectomy for Large-Artery Stroke
This trial studies whether a mechanical procedure to remove a blocked artery can help people with an ischemic stroke caused by a large artery blockage, even when treatment starts 24–72 hours after symptoms began. It also checks that only patients with “salvageable” brain tissue on CT scans are treated.
ShanghaiAges 18 years+ - NCT05327829RecruitingEarly Phase 1
Testing a brain-stimulation approach after concussion recovery
This early study tests whether a brain-stimulation method can help after recovery from a mild to moderate traumatic brain injury (TBI), sometimes called concussion. It also may include healthy volunteers to compare safety and computer-based brain measures.
Minneapolis, MinnesotaAges 18 years+ - NCT05327933Recruiting
Preventing chronic bleeding from the brain’s covering after surgery
This trial looks at whether a procedure called middle meningeal artery embolization can help stop chronic subdural hematoma (slow bleeding/collection under the brain covering) from coming back after your first surgery. It studies an added endovascular treatment right after your operation to reduce recurrence.
Berlin, State of BerlinAges 18 years+ - NCT05331118Recruiting
Study of complications and long-term outcomes after major surgery
This study follows people after planned, higher-risk surgery to learn what complications happen and how patients do long-term. It may help doctors predict risks and improve care for people having similar operations.
UtrechtAges 18 years+ - NCT05331105RecruitingPhase 2
Drug for adults with NF1 and non-surgically treatable nerve tumors
This Phase 2 trial tests HL-085 in adults with neurofibromatosis type 1 (NF1) who have a nerve tumor (plexiform neurofibroma) that cannot be removed by surgery and causes symptoms. It aims to shrink or control the tumor by measuring changes on MRI and monitoring side effects.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT05332756Recruiting
Long-term follow-up of moyamoya care and family health
This trial follows people with moyamoya disease who are treated with medication only, and it also looks at first-degree relatives. The goal is to understand long-term outcomes and whether careful conservative care is beneficial over time.
Beijing, Beijing MunicipalityAges 2–60 - NCT05335187Recruiting
Electrode test during epilepsy surgery planning
This study tests a new “hybrid” type of electrodes placed inside the brain to better map where seizures start in people with difficult (drug-resistant) focal epilepsy. It may help doctors plan safer and more effective surgery, though it involves an invasive brain monitoring procedure.
Bern, Canton of BernAges 18 years+ - NCT05336695RecruitingPhase 1/Phase 2
Brain scan study to measure fibrin in Alzheimer’s
This early study (Phase 1/2) uses brain imaging to look for “fibrin” (a blood-clot–related protein) in people with Alzheimer’s disease and related conditions. The goal is to understand whether fibrin changes can be seen on scans and what it might mean for Alzheimer’s.
Boston, MassachusettsAges 55–90 - NCT05336760Recruiting
ALS study of swallowing comfort, quality of life, and PEG views
This study looks at swallowing problems in people with ALS and how they affect quality of life, including people’s attitudes toward PEG (a feeding tube). It may help researchers understand what support and information could improve comfort and day-to-day living.
LjubljanaAges 18 years+ - NCT05336890Recruiting
Using past oxygen data to predict risks after premature birth
This study builds a personalized computer model that uses earlier breathing/oxygen information from preterm infants to predict possible health or development outcomes by preschool age. It may help families and doctors better estimate risks and plan support, using information already collected in a previous study.
Chicago, IllinoisAges 7 months–6.9 years - NCT05337033RecruitingPhase 2
Testing cannabis for chronic headaches in teens
This trial studies whether cannabis can reduce chronic migraine headaches in adolescents who have not improved with other treatments. It also asks participants to work with psychology and physiotherapy during the study.
Vancouver, British ColumbiaAges 14–17 - NCT05337982Recruiting
Exercise training with stimulation after spinal cord injury
This study tests a special exercise program (with muscle training and possible stimulation) soon after spinal cord injury to see how muscles and the body respond. It also includes healthy adults to compare measurements and biomarkers.
Columbus, OhioAges 18–85
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.