Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,952 recruiting studies in this area right now.
By phase
- Not applicable9,355
- Phase 2761
- Phase 1558
- Phase 3514
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke798
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis328
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke138
- Sarcopenia134
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management116
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California661
- Massachusetts305
- New York295
- Florida272
- Texas266
- Maryland248
- Alabama207
- Arizona206
- Illinois181
- Pennsylvania177
Recruiting studies11,952 total
- NCT04478734RecruitingPhase 2
Thiamine plus biotin for Huntington’s disease symptoms
This Phase 2 study tests whether taking thiamine and biotin together can improve symptoms in people with Huntington’s disease. It looks especially at people with confirmed genetic Huntington’s disease and certain types of movement and/or mood symptoms.
San Sebastián, San SebastianAges 18 years+ - NCT05379855Recruiting
Eye drops for eye alignment and double-vision control in children
This study tests eye drops to improve how a child’s eyes line up and how well they can use both eyes together. It may help children with certain types of outward eye drifting (intermittent exotropia/exophoria).
ShanghaiAges 5–14 - NCT05127980Recruiting
Study of immune antibodies after first-time EBV infection
This study looks at how the immune system’s antibodies behave after a first-time EBV infection, including whether they mistakenly react with the body’s own tissues. You might be offered a chance to help doctors understand why some people get longer or more intense symptoms from infectious mononucleosis.
BaselAges 18 years+ - NCT05402280Recruiting
Study of sleep problems and delirium in hospitalized adults
This study looks at how sleep disturbances may be connected to delirium (sudden confusion) in people staying in the hospital. It may help researchers find ways to prevent delirium by understanding sleep and early warning signs.
Ostrava, Česká RepublikaAges 18 years+ - NCT06224517Recruiting
Artery health after stroke and rehabilitation
This study looks at how well your arteries are working after a stroke and how rehabilitation may help. It uses a simple, painless test (pulse wave velocity) to check artery stiffness.
TaipeiAges 18–80 - NCT06414356RecruitingPhase 4
Ketamine for nerve pain and PTSD in military personnel
This study tests whether ketamine infusions can help with ongoing nerve pain and PTSD symptoms. It's for active-duty service members, veterans, and retirees who have had moderate nerve pain for at least 3 months.
San Antonio, TexasAges 18–70 - NCT06048523Recruiting
Study of genetic brain diseases
This study follows people with a confirmed genetic nerve or brain disease over time, collecting blood and sometimes spinal fluid samples to learn more about the condition. It may help researchers understand how the disease progresses.
BordeauxAges 6 years+ - NCT06158529Recruiting
High-frequency spinal cord stimulation for diabetic nerve pain
This trial tests if a special type of spinal cord stimulation (high-frequency SCS) can better relieve painful nerve damage caused by diabetes. If you have long-term burning, stabbing, or electric-shock-like pain in both legs, this treatment may help reduce that pain.
BeijingAges 18–80 - NCT06453343Recruiting
Comparing two surgical approaches for cochlear implants
This study compares two different surgical methods for placing a cochlear implant (a device that helps with hearing). It is for adults who have lost hearing after learning to speak and are eligible for a specific type of implant. The goal is to see which approach works best.
NijmegenAges 18 years+ - NCT06151392RecruitingPhase 4
Probiotics and zinc for children with brain infection
This trial tests whether adding probiotics (healthy bacteria) and zinc supplements to standard treatment helps children with a brain infection called ventriculitis. It aims to see if these supplements improve recovery and reduce complications.
CairoAges 1 month–4 years - NCT06452914Recruiting
Testing therapeutic socks for diabetic nerve pain
This study tests special socks with tiny electronic parts to see if they can reduce nerve pain, numbness, and tingling in people with diabetic neuropathy. If you have mild to moderate symptoms and are not taking new medications for it, you may be able to join.
Roswell, GeorgiaAges 18–79 - NCT06490276Recruiting
Biofeedback gait training for stroke survivors
This study tests whether a special gait training program with biofeedback (real-time information about your walking) can improve walking quality in people who have had a stroke. It may help you walk better and more naturally.
TaipeiAges 20–80 - NCT06504836Recruiting
Walking feedback in stroke recovery
This study tests a special walking feedback system (like a video game for your legs) for people who had a stroke at least 6 months ago. It aims to improve walking quality, such as how smoothly and evenly you step.
TaipeiAges 20–80 - NCT07367126Recruiting
Nerve pain in knee osteoarthritis: Pain and function study
This study looks at nerve-related pain in people with knee osteoarthritis and how it affects their pain level and daily function. It may help understand if nerve pain is a key factor in your knee OA symptoms.
IstanbulAges 40–70 - NCT07370428Recruiting
Numbing injection for pain relief after lower back surgery
This study tests whether an ultrasound-guided numbing injection near the hip area can provide better pain relief after lower back surgery. If you qualify, you may receive this injection to help control pain after your operation.
BursaAges 18–65 - NCT06764563Recruiting
Mediterranean diet study for multiple sclerosis quality of life
This trial tests whether following a Mediterranean diet can improve quality of life for people with multiple sclerosis (MS). It aims to find a dietary approach that may help manage symptoms and improve well-being.
Tel Aviv, IsraelAges 18–70 - NCT06831357Recruiting
Predicting Cancer Spread in Nasopharyngeal Cancer Using AI
This trial uses a deep learning computer model to look at tissue images and MRI scans to predict whether nasopharyngeal carcinoma may spread to other parts of the body. It may help doctors decide on the best treatment for people with certain stages of this cancer.
Guangzhou, GuangdongAges Any age - NCT07362875Recruiting
Muscle imaging study for myotonic dystrophy
This study uses MRI scans to measure muscle changes in people with myotonic dystrophy (DM1 or DM2) and healthy volunteers. The goal is to find better ways to track the disease over time.
Winston-Salem, North CarolinaAges 18–65 - NCT07364773Recruiting
Motivational interviewing to boost rehab in spinal cord injury
This study looks at whether motivational interviewing—a supportive conversation style—can help patients with spinal cord injury (SCI) participate more fully in their rehab therapy. If you are an adult with SCI receiving inpatient rehab at certain hospitals, you may be able to join.
Chicago, IllinoisAges 18 years+ - NCT07369024RecruitingPhase 2
Study of low-dose ketamine for sickle cell pain crisis
This study tests whether a low-dose of ketamine (a pain medicine) can help children and young adults with sickle cell disease who are in a pain crisis. It aims to provide better pain relief while avoiding some side effects of standard painkillers.
Torrance, CaliforniaAges 5–20 - NCT07365566Recruiting
Pain and sleep behavior disorder study
This study looks at pain in people with a sleep condition called idiopathic REM sleep behavior disorder (iRBD), where people act out their dreams. It also includes a group of people with narcolepsy who have similar sleep issues. The goal is to understand how pain relates to these conditions.
ToulouseAges 18 years+ - NCT07368348Recruiting
Nasal splint vs. flap for CSF leak repair
This trial compares two surgical techniques to repair a cerebrospinal fluid leak (a leak of the fluid around your brain) through the nose. It is for people who have leaks on both sides and have specific conditions in their nasal passage that might make the repair more complex.
Kafr Elsheikh, KafrelsheikhAges 18–70 - NCT07367880Recruiting
Testing a new tool for naming and identifying unique things
This study tests a new tool called the Monument Test, which checks how well people can name and recognize famous landmarks or unique items. It may help assess memory and thinking skills in adults with or without Alzheimer's disease.
GrenobleAges 50–95 - NCT07365917Recruiting
Core exercise for neck nerve pain
This study tests whether core stabilization exercises (exercises to strengthen your trunk and back) can help reduce pain and improve function in people with cervical radiculopathy (a pinched nerve in the neck that causes arm pain and numbness). If you're between 35 and 50, have had neck pain for over six weeks, and your symptoms fit, you may be eligible.
GizaAges 35–50
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,952 recruiting neurology studies from the U.S. registry right now, out of 18,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.