Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,952 recruiting studies in this area right now.
By phase
- Not applicable9,355
- Phase 2761
- Phase 1558
- Phase 3514
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke798
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis328
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke138
- Sarcopenia134
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management116
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California661
- Massachusetts305
- New York295
- Florida272
- Texas266
- Maryland248
- Alabama207
- Arizona206
- Illinois181
- Pennsylvania177
Recruiting studies11,952 total
- NCT07318818RecruitingPhase 1/Phase 2
Revised cell therapy for recurrent brain cancer
This trial tests a new cell therapy (P134 cells) for people whose glioblastoma has come back after standard treatments like radiation or chemotherapy. The therapy uses a patient's own immune cells (PBMCs) to target cancer cells that have specific markers (CD44 or CD133). It also requires a small procedure to place a reservoir under the scalp for drug delivery.
BeijingAges 18–70 - NCT07323953Recruiting
AmblyoFix study for children with lazy eye
This trial tests a new treatment called AmblyoFix for children aged 7 to 12 with lazy eye (amblyopia) in one eye. The study aims to see if it helps improve vision better than standard care.
CairoAges 7–12 - NCT07316153RecruitingPhase 2
Deep sleep study for older adults with insomnia
This study tests a special sleep program to help older adults who have trouble falling asleep or staying asleep. It uses software and may improve your sleep without new medications.
New York, New YorkAges 55 years+ - NCT07322653Recruiting
Supplements to improve fitness in older adults with muscle loss
This study tests whether a special drink (MediDrink Platinum+) and a bean protein supplement can help improve fitness and muscle strength in older adults who are malnourished and have muscle loss. If you are 60 or older, underweight, and have lost muscle, this trial may offer a way to see if these supplements can help you get stronger.
BudapestAges 60 years+ - NCT07322913Recruiting
Study of Intervascular blood vessel grafts and patches
This study is collecting information from patients who have already had surgery to repair or replace blood vessels using Intervascular grafts or patches. Researchers will look at past medical records to see how well these devices work over time.
Hershey, PennsylvaniaAges 18 years+ - NCT07322003RecruitingPhase 3
Pridopidine for ALS: Phase 3 trial testing safety and effectiveness
This trial is testing if an oral medication called pridopidine can slow the progression of ALS. It is for people recently diagnosed with ALS who have mild to moderate breathing function and meet specific risk scores.
Phoenix, ArizonaAges 18–80 - NCT07318714RecruitingPhase 1/Phase 2
Study of ASP2246 for movement problems after a stroke
This study tests an experimental treatment called ASP2246 for people who have movement problems after a stroke. It aims to see if it can help improve arm and leg function when combined with rehabilitation therapy.
Sendai, MiyagiAges 18–80 - NCT07322887RecruitingPhase 2
Study of sul-238 for early untreated parkinson's disease
This study tests whether an experimental medicine called SUL-238 can improve energy levels in the brain cells of people with early, untreated Parkinson's. It uses a special type of MRI to see if the medicine affects brain energy.
GroningenAges 40 years+ - NCT06869928Recruiting
Pain and irritability pathway for children with neurological conditions
This study tests a special care plan for children who have both a significant neurological condition and unexplained pain or irritability. The goal is to help families and doctors work together to better understand and manage these distressing symptoms.
Vancouver, British ColumbiaAges 6 months–18 years - NCT06869486Recruiting
How insomnia affects DNA, heart health, and lifestyle
This study looks at how insomnia affects your DNA, heart health, metabolism, and daily habits. It includes different groups of people—healthy adults, athletes, older adults, university students, and people with metabolic syndrome—to compare the impact of sleep problems.
Ensenada, Estado de Baja CaliforniaAges 18–75 - NCT06869811Recruiting
Stroke prevention after failed blood thinners
This study is for people who had a stroke despite taking blood thinners for atrial fibrillation. It tests if adding a procedure to close the left atrial appendage (a small pouch in the heart) to your blood thinner is better than just taking the blood thinner alone to prevent another stroke.
Barcelona, BarcelonaAges 18–95 - NCT07319091Recruiting
Cystinosis and Mitochondrial Energy Study
This study looks at how cystinosis affects the energy centers (mitochondria) in your cells. It may help doctors understand how cysteamine treatment works in patients with kidney cystinosis.
BronAges 2 years+ - NCT07324330Recruiting
Slowing cognitive decline with exercise in iRBD
This study tests if increasing physical activity can help slow down cognitive (thinking) decline in people with iRBD, a sleep disorder that often leads to Parkinson's or dementia. You'll use a smartphone and a FitBit to track your activity and receive coaching.
Bonn, North Rhine West-FaliaAges 50–80 - NCT07321977Recruiting
Walking test with a portable device for neuromuscular disease
This study tests a portable device that analyzes walking without markers. It aims to see if it can help assess walking in people with neuromuscular diseases and healthy volunteers, which could lead to simpler check-ups.
ParisAges 18–65 - NCT07319117Recruiting
Can a nutritional drink help your brain under stress?
This study tests whether a special nutritional drink can help your brain work better when you're under stress. If you're a healthy woman in her 40s or 50s who drinks coffee daily, you may be able to join.
Leeds, West YorkshireAges 40–60 - NCT07323121Recruiting
Flickering light therapy for sleep problems in Parkinson's
This study tests whether a special flickering light (40 Hz) can help improve sleep in people with Parkinson's disease. Participants will be exposed to the light at home, and researchers will track changes in sleep quality.
Nanjing, JiangsuAges 50–75 - NCT07319013Recruiting
AI Ultrasound for Early Brain Bleed Detection
This trial uses an AI-assisted ultrasound to quickly detect brain bleeding in people with acute stroke. It may help speed up diagnosis and treatment.
Barcelona, CataloniaAges 18 years+ - NCT07323602Recruiting
Predicting DBS outcomes in dystonia with wearable sensors
This trial uses wearable sensors to measure how you walk before and after Deep Brain Stimulation (DBS) surgery for dystonia. The goal is to see if these sensors can help predict how well DBS will work for you.
ShanghaiAges 18–70 - NCT07324109Recruiting
Testing a system for phantom limb pain after leg amputation
This trial is testing a system called Suralis to see if it can help evaluate phantom limb pain — pain that feels like it's coming from a missing leg. It's for people who have had a leg amputated below or above the knee, use a prosthetic regularly, and have daily pain scoring at least 3 out of 10.
Wiesbaden, HesseAges 18 years+ - NCT07323069Recruiting
Nurse-led sleep program for children with cancer
This trial tests a special nurse-led program to help children with cancer sleep better. It includes simple steps to improve sleep and is designed for kids who are between 6 and 12 years old and currently getting cancer treatment.
Kowloon BayAges 6–12 - NCT07323966Recruiting
Mask-free radiation for brain tumor patients
This study tests whether brain tumor patients can safely receive radiation therapy without wearing a face mask. The goal is to see if it is a more comfortable and feasible option.
Woluwe-Saint-Lambert, Brussels CapitalAges 18 years+ - NCT07318129Recruiting
Indole-3-propionic acid for multiple sclerosis
This trial tests an oral supplement called indole-3-propionic acid to see if it can help people with relapsing-remitting multiple sclerosis (RRMS). It involves taking the supplement daily and having regular MRI scans to monitor your MS.
Glostrup MunicipalityAges 18–65 - NCT07318948Recruiting
Blood pressure control in stroke patients receiving thrombolysis
This trial tests a strategy for managing high blood pressure in people having an acute ischemic stroke who are about to receive clot-busting medication. It aims to see if carefully lowering blood pressure within a specific range improves outcomes.
Chengdu, SichuanAges 18 years+ - NCT07319312Recruiting
Nurse-led stroke care support after leaving the hospital in Tanzania
This trial is testing whether a nurse-led program can help stroke survivors and their caregivers after they leave the hospital. It aims to improve recovery and support for those with mild to moderate stroke symptoms.
Dar es SalaamAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,952 recruiting neurology studies from the U.S. registry right now, out of 18,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.