Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,952 recruiting studies in this area right now.
By phase
- Not applicable9,355
- Phase 2761
- Phase 1558
- Phase 3514
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke798
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis328
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke138
- Sarcopenia134
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management116
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California661
- Massachusetts305
- New York295
- Florida272
- Texas266
- Maryland248
- Alabama207
- Arizona206
- Illinois181
- Pennsylvania177
Recruiting studies11,952 total
- NCT07333586Recruiting
Insomnia treatment for better insulin sensitivity
This study tests whether treating insomnia can improve how your body uses insulin (a hormone that controls blood sugar). It may help people with excess weight and poor sleep who are at risk for diabetes.
Columbia, MissouriAges 18–50 - NCT02662751Recruiting
Low-dose whole-body scan after stroke or TIA
This study looks at whether a low-dose whole-body imaging scan soon after a stroke or TIA (sometimes called a “mini-stroke”) can help doctors evaluate you. It also includes long follow-up to see how patients do over time.
MontpellierAges 18–89 - NCT03675087Recruiting
Testing how exercise affects symptoms in ME/CFS
This trial studies how people with ME/CFS respond to an exercise test. It may help researchers understand what kind of exercise response is typical and how it relates to symptoms.
MadridAges 18–65 - NCT04995068Recruiting
Predicting Brain Lesion Risk After Mild Head Injury
This trial studies how to predict who may develop small brain injuries seen on CT scans after a mild traumatic brain injury. It may help doctors decide who needs closer monitoring or follow-up imaging.
StockholmAges 15 years+ - NCT03987633Recruiting
Study links health records and samples to understand health gaps
This study asks people affected by a specific illness (or their family member) to share saliva (and sometimes blood) and answer health and quality-of-life questions. The goal is to better understand and reduce health inequality by matching new information with medical records.
Wolverhampton, West MidlandsAges 6 years+ - NCT06224959Recruiting
Migraine and nerve pain in osteoarthritis study
This study looks at whether people with osteoarthritis also have migraine headaches or nerve pain. Researchers want to better understand these connections to improve treatment.
Clermont-Ferrand, FranceAges 18 years+ - NCT06595329RecruitingPhase 1
Pain relief after kidney cancer surgery: epidural vs spinal opioids
This trial compares two ways to manage pain after open kidney cancer surgery: an epidural (a thin tube placed near your spine) versus a single spinal injection of opioids. Both aim to control pain, but the study wants to see which method works better, with fewer side effects.
SplitAges 18 years+ - NCT06866223Recruiting
Language therapy study for bilingual children ages 4–6
This study looks at how to best support bilingual children (ages 4–6) who have trouble with advanced sentences. It will test whether therapy in English, Spanish, or both helps them learn grammar more effectively.
Houston, TexasAges 4–6 - NCT06866912Recruiting
Observational study of amyloidosis and TTR gene carriers
This study is observing people with amyloidosis or those who carry a specific gene mutation (transthyretin) to learn more about the condition. It does not test any new treatment, but may help researchers understand how the disease affects people.
BolognaAges 18–99 - NCT06866483Recruiting
Online screening for undiagnosed myasthenia gravis
This study tests a new online screening tool to find people who might have undiagnosed myasthenia gravis (a muscle-weakness condition). You answer questions about your symptoms and get more information if the tool suggests you might need to talk to a doctor.
Evanston, IllinoisAges 18 years+ - NCT05006859Recruiting
Wheelchair positioning for people with neuromuscular conditions
This trial looks at improving wheelchair positioning for people with neuromuscular diseases. Better positioning may help comfort, safety, and support day-to-day movement in a wheelchair.
AincourtAges 8 years+ - NCT05389878Recruiting
Stroke patient registry for people within 6 months of stroke
This trial sets up a registry (a secure database) to better track and understand adults who have had an ischemic or hemorrhagic stroke within the last 6 months. Being listed may help researchers learn what care works best for different types and stages of stroke.
FlorenceAges 18 years+ - NCT06156813Recruiting
Turkish lower limb movement log for stroke patients
This study aims to adapt a questionnaire that measures how well stroke survivors can use their legs in daily life. It may help doctors better understand your recovery and guide your rehabilitation.
GaziantepAges 18–80 - NCT06494618Recruiting
Botulinum toxin plus shockwave for leg spasticity in cerebral palsy
This study tests if combining botulinum toxin injections with radial extracorporeal shockwave therapy (RESWT) works better than injection alone for reducing leg spasticity in children with cerebral palsy. If your child has spasticity in leg muscles and is already receiving botulinum toxin, they may benefit from this additional therapy.
Istanbul, KadikoyAges 2–18 - NCT06610994Recruiting
Vibration therapy for stroke recovery
This study tests if a short, local vibration treatment can help stroke patients with leg spasticity (tightness in the calf muscle) improve walking. If you have had a stroke and have mild to moderate spasticity in your lower leg, you may be able to join.
KirikkaleAges 45–75 - NCT06852352Recruiting
Modified brain lymph surgery for Alzheimer's or Parkinson's
This study tests a new, less invasive surgery to improve lymph drainage from the brain. It may help clear harmful proteins linked to Alzheimer's or Parkinson's disease.
Hangzhou, ZhejiangAges 50–80 - NCT06607029Recruiting
Painkiller-free anesthesia for brain tumor surgery
This trial tests whether avoiding opioid painkillers during anesthesia for brain tumor removal can be safe and effective. It may help patients recover with fewer side effects.
BeijingAges 18–65 - NCT06863350Recruiting
Closing a heart hole to treat drug-resistant epilepsy
This trial tests if closing a small hole in the heart (called a PFO) can reduce seizures in people whose epilepsy isn't controlled by medication. It might offer a new treatment option for those who have both drug-resistant epilepsy and this heart condition.
Chengdu, SichuanAges 18–60 - NCT06846177Recruiting
Training programs for fatigue after stroke
This study compares two types of training—graded activity and task-oriented training—to see which one helps reduce fatigue after a stroke. If you are between 40 and 60 years old, had a stroke over 4 months ago, and often feel very tired, you may be able to join.
Mansehra, KPKAges 40–60 - NCT06845657Recruiting
Hip strengthening exercises for knee arthritis
This study tests if strengthening the hip muscles can reduce knee pain and improve function in people with knee osteoarthritis. It may help you if you have had knee pain for at least 3 months and are between 40 and 60 years old.
Islamabad, Punjab ProvinceAges 40–60 - NCT07318870RecruitingPhase 2
Probenecid for reducing seizure clusters during hospital epilepsy monitoring
This trial tests whether a drug called probenecid can help reduce the number of seizures that happen in a cluster during a hospital stay when your seizure medications are being reduced to record your seizures. The goal is to see if giving probenecid can make the monitoring period safer and more effective for people with focal epilepsy being evaluated for surgery.
ParisAges 6–50 - NCT07316543Recruiting
Cognitive rehab for veterans with PNES
This study tests a cognitive rehabilitation program designed to help veterans with psychogenic non-epileptic seizures (PNES) who are having trouble with thinking and memory. The program is done remotely from home using a computer and internet.
Providence, Rhode IslandAges 18 years+ - NCT07316153RecruitingPhase 2
Deep sleep study for older adults with insomnia
This study tests a special sleep program to help older adults who have trouble falling asleep or staying asleep. It uses software and may improve your sleep without new medications.
New York, New YorkAges 55 years+ - NCT07318818RecruitingPhase 1/Phase 2
Revised cell therapy for recurrent brain cancer
This trial tests a new cell therapy (P134 cells) for people whose glioblastoma has come back after standard treatments like radiation or chemotherapy. The therapy uses a patient's own immune cells (PBMCs) to target cancer cells that have specific markers (CD44 or CD133). It also requires a small procedure to place a reservoir under the scalp for drug delivery.
BeijingAges 18–70
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,952 recruiting neurology studies from the U.S. registry right now, out of 18,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.