Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT05859659Recruiting
Hope HOPE study for glioma using pathology and MRI
This study looks at glioma (a type of brain tumor) and uses brain tissue testing, MRI scans, and related measurements to better understand the disease. You may benefit by being closely assessed with MRI and study follow-up, though it’s not necessarily testing a new medicine based on the listed criteria.
Beijing, Beijing MunicipalityAges 18–90 - NCT05861531Recruiting
Oral stimulation and language support for preterm feeding
This study tests whether a feeding-focused therapy that includes mouth stimulation and language support helps preterm babies feed more effectively. It may be most helpful for babies born very early who are learning to feed safely and comfortably.
Providence, Rhode IslandAges 5 months–7 months - NCT05861999RecruitingPhase 4
Risdiplam for young children with SMA after gene therapy plateau
This trial studies whether risdiplam is safe and helpful for children under 2 with spinal muscular atrophy (SMA) whose function has leveled off or declined after gene therapy. It may be an option if you saw benefits from gene therapy but then noticed a stop or setback in key abilities.
Little Rock, ArkansasAges 3 months–2 years - NCT05861752Recruiting
Study of sexual risk behaviors and mental health patterns
This case-control study looks at people with specific sexual behavior-related conditions (like certain paraphilias, compulsive sexual behavior, or sex during sleep) to understand factors linked with risk for sexual violence. The goal is to learn what patterns may be involved so better help and prevention strategies can be developed.
Stockholm, Stockholm CountyAges 18 years+ - NCT05861986RecruitingPhase 4
Risdiplam for very young children after gene therapy for SMA
This trial studies whether risdiplam, given early after gene therapy, is safe and helps children with spinal muscular atrophy (SMA) keep improving or stay stable. It focuses on children under 2 years old who already received gene therapy and need to meet timing and health requirements.
Little Rock, ArkansasAges 3 months–2 years - NCT05862779Recruiting
Omega-3 and whey for muscle strength in postmenopausal women
This study tests whether taking omega-3 and whey protein supplements helps older, postmenopausal women build or keep lean muscle (less fat, more muscle). It also checks safety, especially for heart and kidney health, while you follow a strength-exercise plan.
Uberlândia, Minas GeraisAges 60–85 - NCT05863754Recruiting
Networked device that helps assess hand muscle movement
This trial tests a networked neuroprosthesis device designed to interact with nerves in the arm/hand to help assess grasp and release movements. It may help people with certain long-term spinal cord injuries regain more controlled hand function and researchers measure how well the system works.
Cleveland, OhioAges 16 years+ - NCT05863910Recruiting
Real-world study of medical cannabis use in children
This study looks at how medical cannabis is used for children and teens in everyday life, by collecting information through online questionnaires. It may help doctors and families better understand which uses are common and how people experience them.
Winnipeg, ManitobaAges 3–17 - NCT05864547Recruiting
Study risk factors for seizures after a first stroke
This study looks at what factors can make seizures happen after a first stroke. It may help doctors identify who is more at risk so future care can be better targeted.
TrondheimAges 18–85 - NCT05864157Recruiting
Targeted training to improve walking in Parkinson’s disease
This study tests a targeted motor training approach to improve walking (gait) in people with Parkinson’s disease. You may be considered if your walking is affected but you can already walk steadily for 10 minutes without help.
Chapel Hill, North CarolinaAges 50–80 - NCT05864794Recruiting
Screening brain MRI in advanced lung cancer patients
This trial looks at whether doing an MRI scan of the brain for people with stage IV lung cancer helps in their care. The goal is to find brain issues early (if present) so treatment decisions can be made sooner.
Groningen, Provincie GroningenAges 18 years+ - NCT05864638Recruiting
Registry study of clot-removal treatment for acute stroke
This study records outcomes for people having an acute ischemic stroke treated with an endovascular (catheter-based) procedure. It may help doctors understand how clot-removal treatment works in different patients and hospitals.
ShanghaiAges Any age - NCT05865054Recruiting
MRI check in early suspected giant cell arteritis
This trial tests how well a special MRI (picture scan) can evaluate giant cell arteritis when it’s newly suspected and symptoms started recently. It may help doctors confirm the diagnosis and decide on treatment sooner by comparing MRI findings with standard testing like biopsy or ultrasound.
Rochester, MinnesotaAges 50 years+ - NCT05865093Recruiting
Check early vision changes in infants at risk for brain vision problems
This pilot study looks at early vision (what babies can see and how their eyes respond) in children who have risk factors for future “cerebral visual impairment,” meaning vision problems caused by the brain. It may help doctors spot issues earlier and better understand which early visual signs matter.
RomeAges 2 days–3 years - NCT05865561Recruiting
Breath and skin tests to predict epileptic seizures
This study looks for specific chemicals in a person’s breath or skin (volatile organic compounds) that might help predict seizures. It’s mainly for adults with drug-resistant epilepsy who will undergo at least 48 hours of video EEG monitoring.
ParisAges 18 years+ - NCT05866003Recruiting
Brain stimulation plus hand training after stroke
This trial tests whether a combination of brain stimulation and structured hand practice can improve hand movement for people recovering from stroke. It may help because the training targets upper-limb function while using therapy intended to support recovery.
Cleveland, OhioAges 21–90 - NCT05867173Recruiting
Testing how cochlear implant wiring affects hearing perception
This study looks at how the connection between cochlear implant electrodes and nerve signals changes what you hear. It may help scientists improve how cochlear implants “map” sounds to your brain.
Boston, MassachusettsAges 3 months+ - NCT05867641Recruiting
Immersive VR to help dementia caregivers and improve daily life
This study tests whether immersive virtual reality (VR) can help people with dementia feel better and reduce troubling behaviors, while also giving caregivers a break. If you and a family caregiver qualify, you may use VR as part of an at-home support program.
Oakville, OntarioAges 65 years+ - NCT05867940Recruiting
Exercise program for people with disabilities who are not active
This trial studies whether a structured physical activity program can improve health for people with disabilities who currently do not meet recommended activity levels. It focuses on reducing long periods of sitting and encouraging safer movement.
MalmöAges 8 years+ - NCT05868629Recruiting
Test of two targeted drugs for tumors with BRAF V600E
This trial tests dabrafenib plus trametinib in people whose solid tumors have a BRAF V600E mutation that cannot be fully removed by surgery or has spread. It looks at whether these targeted medicines can shrink tumors and control the disease.
Torrance, CaliforniaAges 1–100 - NCT05868837RecruitingPhase 3
Rituximab for myasthenia gravis in people with moderate symptoms
This Phase 3 trial tests rituximab (an immune system medicine) to see if it improves myasthenia gravis (MG) symptoms and function. It’s for adults with confirmed MG and moderate-to-severe impact on daily activities despite current care.
RomaAges 18 years+ - NCT05868928Recruiting
MRI study of brain metastasis relapse after focused radiation
This study looks at MRI scan patterns to estimate the risk of brain metastases coming back after stereotactic radiosurgery (such as Gamma Knife or CyberKnife). It mainly helps by finding imaging clues that can guide follow-up after treatment.
SeoulAges 18 years+ - NCT05869487Recruiting
Checking muscle loss using a leg measurement and body scan
This study compares a simple calf measurement with a body scan (X-ray–based scan) to help diagnose sarcopenia, which means age-related loss of muscle strength. It may help your care team decide on the best way to recognize muscle loss early during hospitalization and follow-up.
OrléansAges 75 years+ - NCT05871372Recruiting
Study brain circuits behind mood using brain monitoring
This study looks at how brain networks relate to mood and depression by recording brain activity during specific procedures. You may be able to join if you’re already having brain monitoring for epilepsy or are part of a depression deep brain stimulation program.
Houston, TexasAges 21–70
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.