Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT05954845Recruiting
Colonic biopsy study in spinal cord injury gut health
This study looks at how the gut (especially nerve function in the bowel and the gut’s protective lining) works in people with spinal cord injury. It uses planned colonoscopy or rectum/sigmoid exams with small tissue samples to understand whether changes in the gut could contribute to health problems.
NantesAges 18–80 - NCT05955014Recruiting
Study collects data from people with von Hippel-Lindau disease
This study is for people with von Hippel-Lindau (vHL) disease to collect information for research. It may help researchers better understand the condition and how to care for people with it.
Houston, TexasAges 18 years+ - NCT05955469Recruiting
Test two cochlear implant sound-fitting methods
This trial compares two ways of setting up a cochlear implant for adults who need one and speak French. It may help find a fitting approach that gives clearer sound by using a “tonotopy-based” method versus a standard method.
Saint-EtienneAges 18 years+ - NCT05956821RecruitingPhase 1/Phase 2
Study drug for young people with recurring brain glioma
This Phase 1/2 trial tests a study treatment for children and young adults under 22 whose brain glioma has come back or isn’t responding to prior treatment. It’s designed to see whether the treatment is safe and effective for shrinking tumors in this situation.
Miami, FloridaAges 1–21 - NCT05957354Recruiting
Brain stimulation therapy for stroke-related language loss
This trial studies a targeted, non-surgical brain stimulation approach to improve aphasia (language problems) after a first stroke. It may help people regain better language skills by guiding stimulation to specific brain areas.
Jinan, ShandongAges 35–75 - NCT05957549Recruiting
Tracking early sound perception in young children
This study uses special brain-monitoring tools (fNIRS and EEG) to look at how preschool-aged children process sounds. It may help researchers understand early sound perception differences, especially in children with Fragile X Syndrome.
Cincinnati, OhioAges 2–4 - NCT05957445Recruiting
Brain stimulation to improve speech after stroke aphasia
This trial tests a focused brain stimulation approach (cTBS) guided by a planning method (pBFS) to improve language problems after stroke. If you have new stroke-related aphasia, it may help your ability to understand and produce speech as you recover.
Baoding, HebeiAges 35–75 - NCT05958563Recruiting
CPAP may prevent COPD flare-ups in COPD-OSA overlap
This study tests whether using continuous positive airway pressure (CPAP) can reduce acute COPD flare-ups in people who also have sleep apnea. It may help by improving breathing during sleep and lowering the chance of worsening lung symptoms.
AngersAges 40 years+ - NCT05959746Recruiting
AI video tool study for early stroke and TIA diagnosis
This study collects short video and clinical information from people being checked for stroke or a “mini-stroke” (TIA) soon after symptoms start, to help build an AI diagnostic tool. You may be contacted again for a follow-up visit within about 4 months.
Nîmes, GardAges 18 years+ - NCT05960331Recruiting
Study how choice affects learning movement in Parkinson’s
This study looks at whether having more control or “autonomy” helps you learn new movement tasks. It may help researchers find ways to improve physical therapy training for people with Parkinson’s.
TaipeiAges 20 years+ - NCT05959837Recruiting
Testing an adapted rower for people with spinal cord injury
This trial is testing whether an adapted rowing machine works well and is safe for people with spinal cord injuries. You may be able to take part if you use a wheelchair, can row with your arms, and are medically cleared to exercise.
Columbia, South CarolinaAges 18 years+ - NCT05961800Recruiting
Study ways to evaluate lumbar back pain blocks
This study looks at how well different methods can evaluate a common procedure used for chronic low back pain (lumbar medial branch blocks). If you have long-lasting, everyday back pain and are having this procedure, you may help researchers compare evaluation approaches.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05961111RecruitingEarly Phase 1
Oncolytic virus injection for advanced solid tumors
This early-phase trial tests an injection of a virus designed to attack cancer cells in people with advanced solid tumors. It is meant for situations where standard treatments have not worked (or you can’t/won’t take them) and when doctors can directly deliver the treatment to a tumor spot.
Linyi, ShandongAges 18–75 - NCT05961644RecruitingPhase 2/Phase 3
Cladribine vs placebo for non-active progressive multiple sclerosis
This trial tests whether cladribine (vs an inactive placebo pill) can slow disability worsening in people with a non-active, progressive form of multiple sclerosis. It may help by reducing the immune activity that can drive ongoing nerve damage, even without recent relapses.
Warsaw, Masovian VoivodeshipAges 30–65 - NCT05961748Recruiting
Brain and heart illness registry for adults in China
This study is a registry that collects health information from adults who have certain new heart and/or brain conditions. It may help researchers understand how these problems occur together and improve future care planning.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05962177Recruiting
Study of blood tests and scans in relapsing-remitting MS
This study follows adults with relapsing-remitting multiple sclerosis using MRI scans and blood tests. It aims to understand how the disease behaves and what markers in blood and imaging may relate to changes over time.
MontpellierAges 18–59 - NCT05962359Recruiting
Personalized coaching for language in young children with hearing loss
This trial tests a language program designed for young children with hearing loss who are getting cochlear implants. It aims to improve how well children understand and use spoken language, by using a “prediction” approach to tailor support.
Chicago, IllinoisAges birth–5 years - NCT05962489Recruiting
Sleep-focused DBS therapy study for Parkinson’s disease
This study looks at a sleep-focused approach to brain stimulation (DBS) in people with Parkinson’s disease. You may be able to join if you’re planning or scheduled for specific DBS surgery at the University of Minnesota and have the needed brain imaging.
Minneapolis, MinnesotaAges 21 years+ - NCT05963607Recruiting
Weighted blanket trial to reduce chronic pain
This study tests whether using a 15-pound weighted blanket can lower pain and improve sleep for Veterans with long-lasting, non-cancer musculoskeletal pain. It may help by reducing discomfort during rest and sleep.
San Diego, CaliforniaAges 18 years+ - NCT05963698Recruiting
Closing off a heart pouch to prevent stroke
This study tests a procedure that seals off the left atrial appendage (a small heart pouch) to help prevent stroke in people with atrial fibrillation. You may be considered if your stroke risk is high and you are already on blood-thinner medicine.
Birmingham, AlabamaAges 18 years+ - NCT05964712Recruiting
Therapies for acromegaly and effects on body movement
This study looks at how treatments for acromegaly affect how you function and move, especially in your hands, feet, and overall body structure. You may be asked to do assessments to understand changes over time and whether certain groups respond differently.
MilanAges 18–90 - NCT05964140RecruitingPhase 3
Testing antibiotics after jaw fracture surgery
This trial studies whether giving (or how giving) antibiotics affects outcomes after surgery for a broken lower jaw (mandible). It may help reduce infection risk and antibiotic-related side effects if the right approach is chosen for the right patients.
Blackburn, LancashireAges 18 years+ - NCT05964764Recruiting
Check which head-injury guidelines work for children
This study tests and confirms Swedish/Norwegian guidelines for treating minor to moderate head injuries in children. It may help doctors decide the safest next steps after an injury, especially for whether and when to use scans and observation.
HaukelandAges Up to 17 years - NCT05964829Recruiting
Test a leg sleeve to improve walking in multiple sclerosis
This trial studies whether using the Cionic “Neural Sleeve” can improve walking and leg movement in people with multiple sclerosis (MS). It may help if your MS affects mobility, and you can safely wear and tolerate the device during the day.
Cleveland, OhioAges 22–75
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.