Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT05965947Recruiting
Telehealth nutrition coaching for adults after brain injury
This study tests whether regular, online (Zoom) nutrition sessions can help adults living with a brain injury make healthier food choices from home. It’s designed for people who can join sessions by internet and participate in decision-making.
Tuscaloosa, AlabamaAges 18 years+ - NCT05966038Recruiting
Study of ALS and related movement nerve conditions
This study collects and stores medical information from people diagnosed with ALS or certain related conditions affecting movement. It may help researchers better understand how these illnesses change over time and improve future treatments.
Loma Linda, CaliforniaAges 18–90 - NCT05966467Recruiting
Patient registry for AQP4+ neuromyelitis optica on C5 inhibitors
This registry collects health and relapse information from adults with AQP4-positive NMOSD who are taking C5-blocking medicines to prevent long-term relapses. It helps researchers better understand treatment patterns and outcomes in real-world care.
Washington D.C., District of ColumbiaAges 18 years+ - NCT05968053Recruiting
Testing microplastics detection in neurosurgery patients
This study checks whether microplastics and nanoplastics can be detected in people undergoing neurosurgery. If it works, it could help doctors better understand possible material exposures around brain and nerve procedures.
Beijing, Beijing MunicipalityAges 18–80 - NCT05968261Recruiting
Remote coaching for regional anesthesia procedures
This study tests a “near-remote” teaching/coaching approach to help clinicians perform regional anesthesia blocks safely and effectively. You might be able to take part if you’re an adult patient who needs a surgery or injury treatment where a regional block could be used, and you can consent in English.
Kingston, OntarioAges 18 years+ - NCT05968664Recruiting
Test whether new spinal cord stimulation settings improve chronic pain
This trial studies whether changing the “stimulation pattern” of spinal cord stimulation can reduce long-lasting pain and improve daily function. You might be a good candidate if you have chronic trunk or leg pain and have already tried multiple pain treatments without enough relief.
Houston, TexasAges 22 years+ - NCT05968703Recruiting
Deep brain stimulation study for mild memory trouble in Parkinson’s
This trial looks at a specific type of deep brain stimulation (DBS) to see if it can help people with Parkinson’s who have mild cognitive problems (mild memory/thinking changes). You may also be asked to temporarily stop Parkinson’s medications around research visits to measure effects more clearly.
Stanford, CaliforniaAges 21–80 - NCT05968976Recruiting
DBS surgery guided while awake versus asleep for essential tremor
This study compares two ways of doing a deep brain stimulation (DBS) procedure for people with essential tremor: using guidance while you are awake versus while you are asleep. It aims to find which approach is safer and works better for controlling disabling tremor.
Amsterdam, North HollandAges 18 years+ - NCT05969548Recruiting
Brain stimulation to improve stroke-related speech problems
This trial studies different doses of a targeted brain stimulation technique to treat aphasia (language problems) after a first stroke. If you qualify, the goal is to see whether the treatment can improve your ability to understand and speak.
Nanyang, HenanAges 35–75 - NCT05970965Recruiting
Teeth and gum study in children with Down syndrome
This study looks at how gums and inflammation work in children with Down syndrome by collecting and analyzing biological samples. It may help researchers understand gum health differences and improve future care.
Ivry-sur-SeineAges 3–12 - NCT05970562RecruitingEarly Phase 1
Voice therapy plus biofeedback for vocal overuse problems
This early-phase study tests a mix of voice therapy and “biofeedback” (real-time feedback to help you change how you use your voice) for people with vocal overuse symptoms. It may help improve voice quality by targeting muscle tension and strain that happen when the voice is overworked.
Boston, MassachusettsAges 18–65 - NCT05971446Recruiting
Healthy Little Eyes study for newborn vision and brain health
This study looks at eye and vision outcomes in babies who have had lack of oxygen around birth (HIE) and also compares them with healthy “well babies.” It may help doctors better understand how HIE affects the eyes and what to watch for over time.
Madison, WisconsinAges Up to 3 years - NCT05971329Recruiting
Pilot study of bone graft for cervical disc wear and nerve symptoms
This trial tests a new bone graft product (ZetaFuse™) used during front-of-the-neck surgery to treat “wear and tear” in the cervical (neck) discs causing nerve problems. It may help relieve pain and nerve-related symptoms when other treatments haven’t worked.
Randwick, New South WalesAges 22–75 - NCT05971758RecruitingPhase 2
Test drug treatment for pituitary Cushing disease
This Phase 2 trial tests fimepinostat (a targeted cancer-style drug) to help control Cushing disease caused by a pituitary tumor. It’s mainly for adults whose Cushing is confirmed to come from the pituitary and who meet safety and medication-washout rules.
Los Angeles, CaliforniaAges 18 years+ - NCT05972200Recruiting
Brain stimulation to improve reading in dyslexia
This study tests whether a specific kind of brain stimulation can improve reading skills and reading-related abilities in children and teens with dyslexia. It may help by strengthening brain systems involved in reading accuracy and speed.
RomaAges 8–13 - NCT05976152RecruitingPhase 3
Butyphthalide to improve thinking after a recent stroke
This Phase 3 study tests whether butyphthalide can help thinking and memory improve after an acute ischemic stroke. It compares people who take the study medicine versus usual care, and measures cognitive (thinking) changes over follow-up.
Dandong, LiaoningAges 60 years+ - NCT05976490Recruiting
Support program for people newly diagnosed with brain cancer
This study tests a “NeuroPathways” support intervention for adults who are within 6 weeks of being diagnosed with a malignant (cancerous) brain tumor. It may help patients cope and navigate care during the early, stressful period after diagnosis.
Boston, MassachusettsAges 18 years+ - NCT05977088Recruiting
Testing rTMS to help memory in Alzheimer’s
This study tests whether a brain stimulation treatment called rTMS can improve symptoms in people with Alzheimer’s disease. It mainly looks at people with mild to moderate dementia and checks whether results differ based on how the treatment is applied.
IstanbulAges 55 years+ - NCT05977712Recruiting
Circadian rhythm factors in people with memory clinic concerns
This study looks at how daily body-clock timing (circadian rhythm) and other factors may relate to memory and thinking symptoms in memory clinic patients. You may be asked to wear a small device for about 9 days to track your daily patterns.
Paris, FranceAges 18 years+ - NCT05977803Recruiting
MRI study of brain radiation injury in lung cancer
This study looks at how a specific kind of MRI picture (called the CEST sequence) can help characterize radiation-related brain injury and changes in brain metastases from lung cancer. It may help doctors better interpret follow-up scans after radiation, without changing your cancer treatment.
ParisAges 18 years+ - NCT05978206RecruitingPhase 2
Strength, muscle mass, and nutrition therapy for older adults with sarcopenia
This study tests if a combination of a medicine (nandrolone), physical therapy, and a special diet can help older adults with muscle loss (sarcopenia) improve their strength and muscle mass. It is for people age 60 to 99 who have been diagnosed with sarcopenia based on specific muscle strength and mass measurements.
Warsaw, Masovian VoivodeshipAges 60–99 - NCT05978466Recruiting
Managing atrial fibrillation outcomes registry
This registry collects information on people with atrial fibrillation to understand how different treatments affect their health and quality of life over time.
Chicago, IllinoisAges 18 years+ - NCT05978505RecruitingPhase 2
Reboxetine for sleep apnea after ENT surgery
This study tests if the medication reboxetine helps reduce sleep apnea symptoms after planned upper airway surgery. It may be a good fit if you have sleep apnea and are having surgery on your nose or throat.
Bedford Park, South AustraliaAges 18 years+ - NCT05978557Recruiting
Brain tumor drug testing using live tissue samples
This trial uses a small piece of your brain tumor after surgery to test which drugs might work best for you. It helps doctors find the most effective treatment for your specific tumor.
Chapel Hill, North CarolinaAges Any age
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.