Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT06014424RecruitingPhase 2
CBD medication study for agitation in Alzheimer's
This study tests if a CBD medication can help reduce agitation in people with Alzheimer's disease. It's for adults 55 and older who have significant agitation and mild to moderate dementia.
Calgary, AlbertaAges 55 years+ - NCT06014723Recruiting
Balloon angioplasty for recent minor stroke or TIA
This study tests a balloon procedure to open a narrowed artery in the brain to prevent further strokes. It is for people who recently had a mild stroke or high-risk TIA from a significant blockage.
Changchun, JilinAges 30–80 - NCT06015620Recruiting
Health changes after mini gastric bypass surgery
This study looks at how mini gastric bypass surgery helps with obesity-related health problems and changes in body composition. It aims to see if patients experience improvements in conditions like diabetes or high blood pressure.
Bhubaneswar, OdishaAges 18–65 - NCT06015802Recruiting
Predicting pituitary tumor behavior with markers and scans
This study looks at whether blood and tissue markers, along with imaging features, can predict how aggressive a pituitary neuroendocrine tumor is and how it may affect long-term health. It aims to improve treatment decisions by better understanding these tumors.
Guangzhou, GuangdongAges 18–70 - NCT06015971Recruiting
Omega-3 and nutrition support for gastrointestinal cancer
This trial tests whether adding omega-3 fatty acids and extra nutrition support can help people with gastrointestinal cancer who have lost weight. It aims to improve strength and well-being during treatment.
Córdoba, CordobaAges 18 years+ - NCT06016309Recruiting
Understanding Thinking, Energy, Mood, and Behavior in MS
This study looks at how multiple sclerosis affects thinking, energy, mood, and behavior. It uses simple tests and questionnaires to understand your unique profile, which may help tailor future care.
Groningen, Provincie GroningenAges 18–70 - NCT06016387RecruitingPhase 2
Drug combo with radiation for HER2+ breast cancer spread to spinal lining
This trial tests a combination of three targeted drugs (tucatinib, trastuzumab, and capecitabine) along with radiation to the brain or spine for people whose HER2-positive breast cancer has spread to the lining of the brain or spinal cord. The goal is to see if this treatment is safe and effective.
Ottawa, OntarioAges 18 years+ - NCT06016465RecruitingEarly Phase 1
Nerve block plus steroid to prevent migraine return in 72 hours
This trial tests whether adding a steroid pill (dexamethasone) to a nerve block can stop a migraine from coming back within three days. It's for people whose headache got much better after a nerve block.
El Paso, TexasAges 18–85 - NCT06016686RecruitingPhase 1
Recording nerve signals from the vagus nerve in awake humans
This study tests a new way to listen to the vagus nerve in awake people. It may help understand how the nerve controls body functions like heart rate and digestion.
Minneapolis, MinnesotaAges 18–40 - NCT06016946Recruiting
Friedreich's Ataxia Natural History Study
This study follows people with Friedreich's ataxia (FA) over time to learn more about the disease. It helps researchers understand how FA affects people of all ages and may lead to better treatments.
Los Angeles, CaliforniaAges Any age - NCT06017960Recruiting
Dry needling for leg stiffness after stroke
This study checks if a treatment called dry needling (putting thin needles into tight muscles) can help reduce leg stiffness after a stroke. It uses ultrasound and muscle activity readings to see how well it works.
Madrid, MadridAges 18 years+ - NCT06017973Recruiting
Imaging tests for possible non-convulsive status epilepticus
This trial uses advanced imaging scans (PET-MRI) to help doctors better understand and manage a type of seizure that doesn't cause convulsions. It may help improve diagnosis and treatment for people with this condition.
LeuvenAges 16 years+ - NCT06019182Recruiting
MEHMO syndrome: Understanding the condition over time
This study follows people with or at risk for MEHMO syndrome over time to better understand the condition and identify biological markers. It may include both affected individuals and their family members to see how the condition runs in families.
Bethesda, MarylandAges 1 week–100 years - NCT06019949Recruiting
Spinal cord stimulation to improve breathing after spinal cord injury
This trial is testing if a device that sends mild electrical pulses to the spinal cord (spinal cord stimulation) can help improve breathing in people with chronic spinal cord injury. It may be a good option if your injury is above the T5 level and you have reduced lung function.
Louisville, KentuckyAges 18 years+ - NCT06019975Recruiting
Using Brain PET Scans to Diagnose Autoimmune Encephalitis
This study uses a special brain scan (FDG-PET) to better understand autoimmune encephalitis, a condition where the immune system attacks the brain. It may help doctors improve diagnosis by comparing PET scan results with other tests you already had.
Udine, Friuli Venezia GiuliaAges Any age - NCT06021808Recruiting
LAA clip vs. blood thinners to prevent stroke in non-paroxysmal AF
This study compares two ways to prevent stroke in people with persistent or long-standing atrial fibrillation (AF): taking a blood thinner (NOAC) or having a minimally invasive procedure to clip off the left atrial appendage (LAA). The goal is to see which approach works better at preventing stroke without causing major bleeding.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06021938Recruiting
Virtual Reality for Breathlessness in ALS
This trial tests if using immersive virtual reality can help reduce ongoing shortness of breath in people with ALS who already use a breathing mask (non-invasive ventilation). It may offer a drug-free way to feel more comfortable.
Paris, FranceAges 18 years+ - NCT06023706RecruitingPhase 3
Capsaicin patch for tailbone pain
This trial tests a capsaicin 8% patch — a pain-relieving skin patch — to see if it can reduce tailbone pain that has lasted more than 3 months. You may be eligible if you have tried other treatments without success and have nerve-related pain symptoms.
BrestAges 18 years+ - NCT06024122Recruiting
Brain development after mild concussion in young children
This study looks at how a mild concussion affects brain development in young children (ages 3–5) compared to kids with other minor injuries like a broken arm. It involves one MRI scan and some simple check-ups to see how the brain heals over time.
RennesAges 3 years–5.9 years - NCT06025734Recruiting
Nerve stimulation for bladder control in spina bifida
This study tests whether stimulating a nerve in the leg (the tibial nerve) with a small device can help children with spina bifida who leak urine even when using a catheter. The treatment is non-invasive, like a tiny electrical patch near the ankle, and aims to improve bladder control.
Dallas, TexasAges 8–18 - NCT06027645Recruiting
Crawling therapy for very premature infants
This trial tests if early crawling practice on a special skate can help very premature babies at risk for developmental problems. It aims to improve their movement and brain development.
ParisAges 9 months–10 months - NCT06027580Recruiting
Garment to Improve Trunk Control in Infants Age 6-18 Months
This study tests a special compression garment (SPIO Core-MAX) to help babies aged 6-18 months with abnormal muscle tone improve their trunk control. The garment is worn like a tight shirt or vest to provide support.
Milwaukee, WisconsinAges 6 months–1.5 years - NCT06027242Recruiting
Glutamine supplement after stomach cancer surgery
This trial tests if taking glutamine (a nutrient) as an oral supplement helps patients recover after surgery to remove stomach cancer. It aims to see if it improves healing and quality of life.
TaipeiAges 20 years+ - NCT06027294Recruiting
Blood flow and muscle function study for stroke survivors
This study looks at how blood flow affects muscle function after a stroke. It may help researchers understand recovery better and find new ways to improve movement.
Milwaukee, WisconsinAges 18–85
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.