Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT06073886RecruitingPhase 2
Better brain stimulation for long-lasting concussion symptoms
This trial tests whether personalized brain stimulation can help people who have ongoing symptoms more than 20 on a standard concussion scale, such as headaches, dizziness, or trouble concentrating, after a mild head injury in the past year.
Westwood, Los Angeles, CaliforniaAges 18–65 - NCT06074614Recruiting
Breathing and brain control in Parkinson's disease
This study looks at how the brain controls breathing in people with Parkinson's disease compared to healthy volunteers. It may help us understand breathing problems that can occur in Parkinson's.
Nijmegen, GelderlandAges 18 years+ - NCT06074822Recruiting
Biobank study for neuromuscular disease samples
This study collects leftover tissue from muscle or nerve biopsies to build a biobank for future research on neuromuscular diseases. It may help improve diagnosis and treatment for conditions like yours.
BordeauxAges Any age - NCT06075693Recruiting
Spinal fluid markers for myotonic dystrophy
This study looks for markers in spinal fluid that could help doctors better understand myotonic dystrophy type 1 (DM1). It involves a spinal tap and MRI scan. It may help people with DM1 and healthy volunteers learn more about the condition.
Boston, MassachusettsAges 18 years+ - NCT06075485Recruiting
Ketogenic diet for drug-resistant epilepsy in children
This study looks at how well the ketogenic diet (a high-fat, low-carb diet) works for children with epilepsy that doesn't improve with standard medicines. It uses a special product called KetoCal to help maintain the diet and tracks results in real life.
LilleAges 5 months–18 years - NCT06075628Recruiting
CT scan study after LAA closure procedure
This study looks at long-term outcomes after LAA closure (a procedure to reduce stroke risk) by reviewing CT scans of the device. It aims to learn if blood flow around the device affects healing and future health.
Overland Park, KansasAges 18 years+ - NCT06075771RecruitingPhase 4
Testing a Parkinson's drug for depression-related loss of interest
This trial tests whether a medication used for Parkinson's disease (carbidopa-levodopa) can help people with major depression who have lost interest or pleasure in things. It is for adults who have not been helped enough by other treatments and have signs of inflammation.
Atlanta, GeorgiaAges 25–55 - NCT06076928Recruiting
Brain-computer interface glove for hand recovery after stroke
This trial tests a robotic glove controlled by your brain signals to help improve hand function after a stroke. It is for people who had a stroke at least 16 weeks ago and have some movement in their shoulder and elbow but limited hand control.
Singapore, SingaporeAges 21–85 - NCT06075914Recruiting
Ketones and sleep: can nutrition help?
This study tests if a special nutritional supplement (ketones) can help your body stay resilient when you don't get enough sleep. If you join, you'll follow a specific diet and have your sleep and health monitored for about 9 weeks.
Columbus, OhioAges 18–40 - NCT06077227Recruiting
Virtual reality for phantom limb pain
This study tests whether virtual reality therapy can help reduce phantom limb pain or uncomfortable sensations after amputation. If you have a major limb amputation and feel pain or other sensations in the missing limb, this might be an option to try.
Charlotte, North CarolinaAges 18 years+ - NCT06077747Recruiting
Lumbar vein treatment for chronic headaches with nutcracker anatomy
This study tests a procedure called lumbar vein embolization to treat daily headaches that feel like pressure and get worse when lying down. It's for people who have a rare anatomy where a vein in the kidney is pinched (nutcracker physiology), and standard headache medicines haven't helped.
Jacksonville, FloridaAges 18 years+ - NCT06077838Recruiting
RELAXaHEAD app test for migraine relief
This study tests a smartphone app called RELAXaHEAD that teaches relaxation techniques to help people with migraine. If you have 4–29 headache days per month and haven't tried relaxation therapy for headaches recently, this app might help reduce your symptoms.
New York, New YorkAges 16–80 - NCT06079294Recruiting
Autoimmune encephalitis and brain glucose metabolism
This study looks at how autoimmune encephalitis affects brain metabolism using a special PET scan. It aims to better understand the condition in people who were recently diagnosed.
ParisAges 18 years+ - NCT06079021Recruiting
Study of a blood filter for sudden liver failure
This trial tests a device called CytoSorb that filters the blood to reduce inflammation in patients with sudden worsening of chronic liver disease. It may help support organ function and recovery.
Edegem, AntwerpAges 18 years+ - NCT06080646Recruiting
Depression and Reward Processing Brain Study
This study uses brain scans (MRI) to understand how people with depression process rewards, aiming to identify different depression subtypes. You may join if you have depression or if you are a healthy volunteer.
San Francisco, CaliforniaAges 18–70 - NCT06080659Recruiting
Brain network study for Alzheimer's and Parkinson's
This study uses brain scans to look for patterns that might help diagnose memory or movement problems like Alzheimer's or Parkinson's disease. It compares people with mild symptoms, like forgetfulness or early Parkinson's, to healthy volunteers.
RennesAges 50–80 - NCT06081036Recruiting
Normal brain volumes from fetal MRI scans
This study looks at past fetal MRI scans to create a map of normal brain growth in babies before birth. It may help doctors better understand what healthy brain development looks like.
MarseilleAges 5 months–9 months - NCT06081062RecruitingPhase 3
Testing Fabagal in people with Fabry disease
This trial is testing a new enzyme replacement therapy called Fabagal for people with Fabry disease who have not had prior treatment. It aims to see if it helps with kidney, heart, or brain problems caused by the disease.
ManilaAges 8 years+ - NCT06081998Recruiting
How lack of sleep affects itch and pain
This study looks at how not sleeping affects your sensitivity to itch and pain. Researchers want to understand the connection between sleep and these sensations, which could help treat conditions like chronic itching or pain.
AalborgAges 18–60 - NCT06081946Recruiting
Does broken sleep affect itch and pain sensitivity?
This study looks at how a poor night's sleep (short, broken sleep) affects your sensitivity to itching and pain. The goal is to understand if sleep problems might make skin conditions worse.
AalborgAges 18–60 - NCT06082713Recruiting
Extracellular Vesicles Study for Huntington's Disease
This study is collecting tiny particles called extracellular vesicles from blood and spinal fluid to learn more about Huntington's disease. It aims to find better ways to measure the disease in people who have HD and in those who do not.
Orlando, FloridaAges 18–75 - NCT06083298Recruiting
Nerve blocks for pain after cervical spine surgery
This trial tests two types of nerve blocks to see which works better for pain after back-of-the-neck surgery. It aims to help patients have less pain and use less opioid medicine.
Zagazig, AlsharqiaAges 21–60 - NCT06083467Recruiting
Brain imaging study for Parkinson's and related disorders
This study uses brain imaging and tests to better understand Parkinson's disease and related conditions. It aims to improve diagnosis by comparing scans across different groups of people.
Philadelphia, PennsylvaniaAges 40–85 - NCT06083584Recruiting
Using RNA test to help diagnose ALS
This study is developing a new RNA test to improve the accuracy of diagnosing amyotrophic lateral sclerosis (ALS). It aims to see if this test can help doctors make a clearer and faster diagnosis.
BordeauxAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.