Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT06084026Recruiting
Measuring daily activity with a small leg monitor
This study uses a small device called ActivPal clipped to your leg to measure how much you move during daily life. Researchers want to compare activity levels between people with neuromuscular disorders and healthy volunteers to better understand physical activity patterns.
New York, New YorkAges 1 year+ - NCT06085300Recruiting
Bilingual treatment study for children with language delays
This study looks at how bilingual children with language delays respond to treatment in English or Spanish. It aims to find the best way to help them improve their language skills.
Houston, TexasAges 4–6 - NCT06086561Recruiting
Testing a wireless device to monitor CSF shunt flow
This study tests a new wireless device that measures fluid flow in a CSF shunt (a tube that drains fluid from the brain). You may join if you have a shunt under your skin across your collarbone and can use or be nearby the device for a month.
Tampa, FloridaAges 5–80 - NCT06085612Recruiting
How carotid artery blockage affects blood flow in the retina
This trial examines how a narrowing of the main neck artery (carotid stenosis) impacts blood flow in the retina using a special eye test called automated retinal oximetry. The goal is to better understand how this blockage affects eye health.
OlomoucAges 18 years+ - NCT06086366Recruiting
Brain scan study for depression after COVID-19
This study uses brain scans to understand depression that starts soon after COVID-19. Researchers want to see if there are changes in brain chemistry related to depression, and you may help find new treatment targets.
Toronto, OntarioAges 18–75 - NCT06086951Recruiting
Chatbot-based therapy for caregivers of children with special needs
This trial tests an AI-powered chatbot that delivers Acceptance and Commitment Therapy (ACT) to help Cantonese-speaking caregivers in Hong Kong manage stress and improve their parenting skills. It is designed for caregivers who live with a child aged 2–8 with autism, ADHD, or developmental delay.
Hong KongAges 19 years+ - NCT06088212Recruiting
Heart failure treatment to help thinking and memory
This trial tests whether better managing heart failure after a hospital stay can protect against thinking and memory problems. It is for people who have heart failure and have had some cognitive difficulties.
Hobart, TasmaniaAges 18 years+ - NCT06087393Recruiting
Brain tumor surgery imaging study
This study tests a special microscope that helps surgeons see brain tumors more clearly during surgery. The goal is to see if it can help remove more of the tumor safely.
Manhasset, New YorkAges Any age - NCT06088628Recruiting
Facial micro-expressions in long-term consciousness disorders
This study looks at tiny, unconscious facial expressions in patients who have been in a vegetative or minimally conscious state for over a month after a severe brain injury. The goal is to see if these micro-expressions can help doctors better understand a patient's level of awareness.
Hangzhou, ZhejiangAges 18–80 - NCT06088121Recruiting
TMS with cognitive training for mild Alzheimer's dementia
This study tests a combination of brain stimulation (TMS) and cognitive training to improve memory and thinking in people with mild Alzheimer's. It may help if you are already on a stable dose of a donepezil-type medication and have a confirmed Alzheimer's diagnosis.
Incheon, Bupyeong 6(yuk)-dong, Bupyeong-guAges 60–85 - NCT06088953Recruiting
Early hearing check for memory clinic patients
This study looks at how to detect hearing loss early in people with mild to moderate memory problems. It may help understand if hearing issues affect thinking skills.
LilleAges 50 years+ - NCT06088589Recruiting
Speech-in-noise in autism and fragile x
This study measures how well people with autism or fragile X syndrome perceive speech in noisy settings, compared to typically developing individuals. It uses EEG to understand brain activity during listening tasks.
Cincinnati, OhioAges 15–35 - NCT06089161Recruiting
Sleep Apnea Treatment and Alzheimer's Risk in Black Adults
This trial tests whether personalized sleep apnea treatment can help protect memory and thinking in Black older adults. If you have sleep apnea and are concerned about Alzheimer's, this study may help you and others like you.
Miami, FloridaAges 60–85 - NCT06089096Recruiting
Sleep apnea and memory in people with mild memory problems
This study looks at whether sleep apnea (pauses in breathing during sleep) is linked to thinking and memory in people who have mild memory problems. You will do a home sleep test and take memory tests to help researchers find this connection.
Hong KongAges 18 years+ - NCT06089603RecruitingPhase 4
CPAP for Sleep Apnea with High Red Blood Cells
This study tests whether CPAP therapy (a machine that helps keep your airway open while you sleep) can lower high red blood cell counts in people who have both sleep apnea and polycythemia. It may help reduce the need for other treatments.
Madrid, MadridAges 18–80 - NCT06089915Recruiting
Robot-assisted arm exercise for cervical spinal cord injury
This trial tests a robot that helps move your arms if you have a cervical spinal cord injury. It may improve arm strength and function through guided exercise.
LjubljanaAges 18 years+ - NCT06090201Recruiting
Brain health study for severe bleeding disorders
This study uses brain scans and thinking tests to understand how severe hemophilia or von Willebrand disease affects the brain and memory over time.
LilleAges 18 years+ - NCT06090383Recruiting
Movement tracking study for teens with cerebral palsy
This study tests whether small movement sensors can accurately track how much and how well teenagers and young adults with cerebral palsy move during daily life. The results may help doctors better understand movement problems and design better therapies.
CopenhagenAges 15–25 - NCT06090578Recruiting
Brain health check for adults in primary care
This trial tests a new brain health assessment tool in primary care clinics. It may help your doctor better detect thinking or memory changes early.
Pasadena, CaliforniaAges 18 years+ - NCT06090682Recruiting
Brain stimulation for Parkinson's with thinking problems
This trial tests a brain stimulation technique (deep brain stimulation) to see if it can help people with Parkinson's disease who also have mild cognitive problems. The goal is to understand how stimulation affects both movement and thinking.
Tianjin, Tianjin MunicipalityAges Up to 75 years - NCT06091332RecruitingPhase 2
Sirolimus for brainstem cavernoma bleeding
This trial tests if sirolimus, a medicine that may help reduce abnormal blood vessels, can prevent another brain bleed in people who recently had a bleed from a brainstem cavernoma. You would receive either sirolimus or a placebo to see if it works.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06091319Recruiting
Florbetaben imaging for vascular amyloid after heart or brain event
This trial tests whether florbetaben, a special dye, can show amyloid buildup in blood vessels after a recent heart attack, chest pain episode, or stroke. It aims to help doctors better understand and prevent future events.
Ottawa, OntarioAges 18 years+ - NCT06092034RecruitingPhase 2
Gene therapy for Danon disease in males
This trial tests a gene therapy called RP-A501 for men with Danon disease, a heart condition. It aims to replace the faulty gene that causes the disease to improve heart function.
La Jolla, CaliforniaAges 8 years+ - NCT06092125Recruiting
Brain disease imaging study with PET/MR scans
This trial uses advanced PET and MR scans to better understand and diagnose brain diseases like Alzheimer's, Parkinson's, epilepsy, and brain tumors. It may help identify new ways to track these conditions.
Beijing, Beijing MunicipalityAges 18–60
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.