Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT06092554Recruiting
Probiotics to prevent pneumonia in ventilated patients
This trial tests whether giving probiotics to patients on a breathing machine (mechanical ventilation) can help prevent pneumonia. It is for adults who are on a ventilator after a recent head injury, stroke, or brain bleed.
BrusselsAges 18–80 - NCT06092346Recruiting
Understanding rare purine and pyrimidine metabolism disorders
This study aims to learn more about rare disorders of purine and pyrimidine metabolism (DPPM), which can affect the brain, immune system, kidneys, and muscles. Researchers will study people with these disorders, their family members, and healthy volunteers to better understand the condition over time.
Bethesda, MarylandAges 1 month–100 years - NCT06092749Recruiting
A new treatment for chronic leg and back pain
This trial tests a procedure for people with long-standing leg and back pain that hasn't improved with standard treatments like physical therapy or pain medicine.
CairoAges 21 years+ - NCT06092671Recruiting
Can FPCA prevent confusion in young kids after surgery?
This study tests whether a medicine called FPCA can prevent sudden confusion (delirium) in young children after surgery. If your child is having short surgery with mask anesthesia for the first time, this study may help them have a smoother recovery.
Wenzhou, ZhejiangAges 2–6 - NCT06092814Recruiting
Brain stimulation to boost language after stroke
This study tests whether a gentle electrical current (tACS) applied to the scalp can improve language abilities in people with aphasia after a stroke. Healthy volunteers are also needed as a comparison group.
Philadelphia, PennsylvaniaAges 18–85 - NCT06093100Recruiting
Wearable device study for Duchenne muscular dystrophy
This study uses a wearable device to track blood sugar levels and heart rate in people with Duchenne muscular dystrophy. It aims to understand how these factors relate to heart health over time.
Nashville, TennesseeAges 10 years+ - NCT06093126RecruitingPhase 4
Lemborexant for insomnia in dementia: a personalized trial
This trial tests if the sleep medication lemborexant can help people with early-stage dementia who also have insomnia. It uses an N-of-1 design, meaning it will look at how you personally respond to the drug compared to a placebo.
Halifax, Nova ScotiaAges Any age - NCT06093633Recruiting
Sleep study comparing new device to standard method
This study tests a new wearable device (WP) against standard sleep testing (PSG) for people with suspected sleep problems. It may help diagnose issues like sleep apnea more comfortably.
Baltimore, MarylandAges 12–99 - NCT06094205Recruiting
BrainGate2 speech study for people with tetraplegia
This study tests a brain-computer interface to help people with severe paralysis communicate by decoding attempted speech or movements. It may offer a new way to interact with devices using only brain signals.
Sacramento, CaliforniaAges 18–80 - NCT06094478Recruiting
Stroke emergency protocol study
This study tests a hospital stroke protocol to quickly evaluate and manage patients with a stroke caused by a clot (AIS), bleeding in the brain (ICH), or bleeding around the brain (SAH). It may help improve emergency care and outcomes.
New Haven, ConnecticutAges 18 years+ - NCT06094257Recruiting
Study on sensation and satisfaction after mastectomy
This study looks at how people feel after mastectomy, including transgender patients and those having nipple-sparing surgery. It aims to understand sensation and satisfaction to improve future care.
Boston, MassachusettsAges 18 years+ - NCT06094192Recruiting
Brain stimulation to improve memory in Alzheimer's
This study tests whether a gentle, noninvasive brain stimulation technique called tACS can help improve memory in people with Alzheimer's disease or mild cognitive impairment. It may also include healthy older adults for comparison.
Boston, MassachusettsAges 50–100 - NCT06094855Recruiting
Cooling and balance in multiple sclerosis
This trial tests if cooling therapy can improve balance in people with multiple sclerosis. If you can stand without help for at least one minute, you may qualify.
New York, New YorkAges 18–75 - NCT06095063Recruiting
Magnetic brain stimulation for memory concerns with family Alzheimer's history
This study tests whether a type of magnetic brain stimulation (dTMS) can help people who are worried about their memory. It is for people who have a family history of Alzheimer's but are still thinking clearly.
Toronto, OntarioAges 55–70 - NCT06096350Recruiting
Nutrition and recovery in recent stroke patients
This study looks at how nutrition affects recovery in people who had a stroke within the last 6 months. It aims to help improve rehabilitation by checking your nutritional status.
Roma, RMAges 18–90 - NCT06096272Recruiting
Using augmented reality to help kids with cerebral palsy be more active
This trial tests if using an augmented reality game on a tablet can help children with cerebral palsy walk and move more each day. It could be an option if your child can walk on their own and doesn't have upcoming leg surgery.
Los Angeles, CaliforniaAges 5–18 - NCT06097000Recruiting
Smart exoskeleton for leg recovery after spine surgery
This trial tests whether a powered exoskeleton can help people who have leg weakness after spinal surgery improve their walking at home. If you've had spinal surgery within the past year and can walk a bit, this device may help retrain your legs.
Beijing, Beijing MunicipalityAges 18–70 - NCT06096740Recruiting
Talking therapy for PTSD and its effects on the brain
This study looks at how a specific type of talk therapy affects the way your brain processes rewards. You'd join a group that either starts therapy right away or waits a bit before starting. Your brain activity will be scanned with an MRI to see changes.
Austin, TexasAges 18–65 - NCT06097091Recruiting
Pain education for fibromyalgia patients
This trial tests if learning about how your brain and nerves process pain can help reduce fibromyalgia symptoms. You will attend sessions that teach you about the science of pain and how to manage it better.
TaipeiAges 18–64 - NCT06097195Recruiting
EEG test to help diagnose epilepsy after a first seizure
This trial studies a new way of analyzing EEG results to help doctors decide if a first suspected seizure was caused by epilepsy. If you had a first seizure and your EEG did not show clear signs of epilepsy, this test might improve your diagnosis.
TruroAges 18 years+ - NCT06098235Recruiting
Test of the Oriental diet for brain health in people at high stroke risk
This trial tests whether a special diet (the Oriental diet) can help protect thinking and memory in people who have several stroke risk factors. It may be a good fit if you are 40 or older and have three or more stroke risk factors, such as high blood pressure, diabetes, or being overweight.
Hangzhou, ZhejiangAges 40 years+ - NCT06098482Recruiting
Testing speech understanding with a mobile app for hearing device users
This study uses a smartphone app to test how well adults who use hearing aids or cochlear implants can understand speech. It aims to see if the app is a reliable way to measure hearing performance, which could make future check-ups easier and more convenient.
Lone Tree, ColoradoAges 18 years+ - NCT06098833RecruitingPhase 2
Sildenafil for newborn brain injury after birth asphyxia
This trial tests whether a liquid form of the medicine sildenafil can help repair brain damage in newborns who had a difficult birth and were treated with cooling. If your baby meets the cooling criteria and has brain injury on an MRI, this study may offer an additional treatment option.
Montreal, QuebecAges birth–2 days - NCT06098612RecruitingEarly Phase 1
PET imaging study for Parkinson's and related disorders
This study uses a new PET scan tracer called [11C]SY08 to take pictures of the brain in people with Parkinson's, multiple system atrophy, or dementia with Lewy bodies. It aims to see if this tracer can help better understand and tell apart these conditions.
Charlestown, MassachusettsAges 50–80
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.