Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,435 recruiting studies in this area right now.
By phase
- Not applicable9,772
- Phase 2786
- Phase 1573
- Phase 3535
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3123
Top conditions
- Stroke846
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California680
- Massachusetts300
- New York291
- Florida274
- Texas268
- Maryland245
- Arizona214
- Alabama209
- Illinois190
- Pennsylvania177
Recruiting studies12,433 total
- NCT06117579Recruiting
Breathing Muscle Training for Sleep Apnea
This trial tests whether a simple breathing exercise (training the muscles you use to breathe in) can improve sleep apnea symptoms in people who already use CPAP. The goal is to see if adding this training helps you feel better or need less CPAP pressure.
OrléansAges 18 years+ - NCT06117930Recruiting
Brain tumor and gut bacteria study
This study looks at how the bacteria in your gut might be linked to brain tumors. Researchers want to collect samples (like stool and tissue) during brain surgery to better understand this connection.
Jacksonville, FloridaAges 18 years+ - NCT06118723Recruiting
Supramaximal vs maximal surgery for brain tumors
This trial compares removing as much tumor as safely possible (supramaximal resection) with standard maximal resection in people with high-grade glioma (an aggressive brain tumor). The goal is to see if more extensive removal improves survival and quality of life.
San Francisco, CaliforniaAges 18–90 - NCT06118736Recruiting
Guided bone growth to prevent hip problems in children with cerebral palsy
This trial tests a surgery to guide the growth of the upper thigh bone (femur) to keep the hip joint from sliding out of place in children with spastic cerebral palsy. It aims to prevent further hip migration and avoid more serious hip problems later.
AmsterdamAges 2–8 - NCT06118840Recruiting
AI tool for spotting brain aneurysms on CT scans
This trial tests if an AI model can help doctors detect brain aneurysms more accurately on head CT angiograms (CTA). It may lead to earlier treatment and better outcomes.
Hefei, AnhuiAges 18 years+ - NCT06119061RecruitingPhase 4
Telavancin levels in patients with external ventricular drain
This study measures how much of the antibiotic telavancin reaches the fluid around your brain and spine when you have a drain in place. It will help doctors understand if this drug is effective for treating brain infections.
Lexington, KentuckyAges 18–85 - NCT06120049RecruitingPhase 2/Phase 3
Comparing new PET scans for Parkinson's, MSA, Lewy body dementia, and Alzheimer's
This study tests if a new radioactive tracer called [18F]-MFBG can help doctors better distinguish between Parkinson's disease, multiple system atrophy (MSA), dementia with Lewy bodies, and Alzheimer's disease. It compares the new scan with two standard scans to see which is most accurate.
Ghent, GentAges 18–85 - NCT06120426Recruiting
Surgery types and radiation for spinal tumors that have spread
This study compares two types of spinal surgery combined with radiation for people whose cancer has spread to the spine in a limited way (no more than 5 spots). It aims to find which approach better controls pain, tumor growth, and spinal stability.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06120218Recruiting
Stenting for blocked neck and brain artery in severe stroke
This trial tests a treatment for people having a severe stroke when a large artery in the neck and a brain artery are both blocked. The treatment involves opening the neck artery with a stent (a small tube) and then clearing the brain clot, all within 24 hours of symptom onset.
Can ThoAges 19–100 - NCT06120361Recruiting
Primary care study for early cognitive decline
This research study looks at people who have noticed problems with memory or thinking (like trouble focusing or finding words) and visit their primary care doctor for help. It aims to better understand and diagnose conditions that cause these symptoms, such as Alzheimer's disease.
MalmöAges 40 years+ - NCT06121219Recruiting
Can visual retraining after stroke improve sight?
This trial tests whether special computer-based visual exercises can help people whose vision was damaged by a stroke. You would do the exercises at home for several months.
Rochester, New YorkAges 21–80 - NCT06121011Recruiting
Pompe disease patient registry study
This is a registry study that collects information over time from people with Pompe disease. It helps doctors and researchers better understand the condition and how it affects daily life, without testing any new treatments.
Little Rock, ArkansasAges Any age - NCT06121544Recruiting
Pre-Alzheimer's Study: Find Early Brain Changes
This study is looking for healthy volunteers to help detect the very earliest signs of Alzheimer's disease—before memory loss starts. You will have tests like memory checks, blood draws, brain scans, and a spinal tap to look for Alzheimer's-related changes.
MalmöAges 50–80 - NCT06122675Recruiting
Deep brain stimulation for movement problems in children with cerebral palsy
This study tests whether deep brain stimulation (a small device placed in the brain that sends electrical pulses) can help improve movement problems in children and young adults with a certain type of cerebral palsy. The goal is to see if it can reduce involuntary movements like twisting or jerking.
San Francisco, CaliforniaAges 7–25 - NCT06122415Recruiting
Memory clinic study with fluid and cognitive tests
This study looks at people who are being checked for memory or thinking problems. It uses standard tests done at the memory clinic, like a spinal tap and blood draw, plus memory and thinking tests, to learn more about these symptoms. You can join if these tests are already planned as part of your regular care, even if you don't take part in the study.
MalmöAges Any age - NCT06123325Recruiting
Mental health and quality of life after unruptured brain aneurysm diagnosis
This trial looks at how being diagnosed with an unruptured brain aneurysm (a weak spot on a blood vessel that hasn't bled) affects your mood, anxiety, and quality of life. It also compares outcomes for people who get treatment (like surgery or a catheter procedure) versus those who are watched with scans.
The Bronx, New YorkAges 18–75 - NCT06123650Recruiting
Magnetic brain stimulation plus therapy for swallowing after stroke
This study tests whether adding a gentle magnetic brain stimulation (called rTMS) to standard swallowing therapy can help prevent pneumonia in people who have trouble swallowing after a stroke. It might reduce the risk of getting a lung infection.
Giza, Giza GovernorateAges 49–65 - NCT06124196Recruiting
Wearable device study for Duchenne muscular dystrophy
This study uses a wearable device to track your blood sugar levels and heart rate patterns over time. It aims to understand how these are related to Duchenne muscular dystrophy (DMD) and may help improve care.
Nashville, TennesseeAges 10 years+ - NCT06124248Recruiting
RISE program to help stroke survivors sit less and move more
This study tests if a program called RISE can help people who have had a stroke reduce the amount of time they spend sitting. The goal is to see if it helps improve recovery and daily life after returning home from the hospital.
's-Hertogenbosch, North BrabantAges 18 years+ - NCT06124586Recruiting
Early angioplasty for diabetic foot ulcers
This trial tests if an early procedure to open blocked leg arteries (angioplasty) helps heal foot ulcers in people with type 2 diabetes. It aims to improve blood flow and prevent amputation.
DüsseldorfAges 18 years+ - NCT06125236Recruiting
Stroke study for large artery blockages in Southwest China
This study is collecting information from people in Southwest China who have had a stroke caused by a blocked large or medium artery. The goal is to learn more about these strokes and how to treat them better.
LuzhouAges Any age - NCT06126315RecruitingPhase 2/Phase 3
Testing acetyl-L-carnitine in early ALS
This study tests a supplement called acetyl-L-carnitine (ALCAR) to see if it can slow the progression of ALS. It is for people in the early stages of the disease who are already taking riluzole and have good lung and muscle function.
SydneyAges 18 years+ - NCT06126588RecruitingPhase 2
Everolimus and Lutathera for refractory meningioma
This trial tests a combination of two drugs (everolimus and 177Lu-DOTATATE) for people with grade 2 or 3 meningioma that has grown despite prior treatments. It aims to see if this combination can slow or stop tumor growth.
Vandœuvre-lès-Nancy, Grand EstAges 18–80 - NCT06126627Recruiting
Brain and voice study for teachers with vocal fatigue
This study looks at how vocal fatigue affects the brain and voice in teachers. It uses MRI and voice tests to understand these changes.
BonnAges 21–39
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,435 recruiting neurology studies from the U.S. registry right now, out of 19,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.