Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,435 recruiting studies in this area right now.
By phase
- Not applicable9,772
- Phase 2786
- Phase 1573
- Phase 3535
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3123
Top conditions
- Stroke846
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California680
- Massachusetts300
- New York291
- Florida274
- Texas268
- Maryland245
- Arizona214
- Alabama209
- Illinois190
- Pennsylvania177
Recruiting studies12,433 total
- NCT06157268Recruiting
Study of muscle tiredness in congenital myopathies
This study follows patients with congenital myopathies to understand how their muscles get tired over time. It may help develop better treatments.
Nijmegen, GelderlandAges 2 years+ - NCT06157502RecruitingPhase 3
Shuxuening with clot-busting treatment for ischemic stroke
This trial tests if adding the herbal injection Shuxuening to standard clot-busting treatment improves recovery for people having an ischemic stroke. It is for adults within 6 hours of symptom onset who are already receiving a clot-dissolving medication.
Beijing, Beijing MunicipalityAges 18–100 - NCT06157866Recruiting
Cognitive training with acupuncture for fibromyalgia pain
This study tests whether a type of mental training (cognitive training) can help your brain respond better to acupuncture for fibromyalgia pain. You would receive acupuncture while doing a thinking task, and the study will use brain scans to see how your brain changes.
Charlestown, MassachusettsAges 18–65 - NCT06158087Recruiting
Stent-assisted coiling for wide-neck brain aneurysms
This trial tests a new stent-assisted coiling procedure for people with wide-neck brain aneurysms. The goal is to see if the treatment is safe and effective, and you might be a good candidate if you haven't had previous aneurysm treatment and are in generally good health.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06158750Recruiting
Flow diverter for brain aneurysms: safety and effectiveness study
This trial tests a device called a flow modulation device to treat certain brain aneurysms. It aims to see if the device is safe and works well for people with aneurysms that have not burst.
BeijingAges 18–80 - NCT06159335RecruitingPhase 3
PET/MR scan for brain metastasis imaging
This trial uses a special PET/MR scan with a radioactive tracer to help tell the difference between tumor regrowth and changes from radiation treatment in people with brain metastases. It may help doctors make better treatment decisions.
Madison, WisconsinAges 18 years+ - NCT06159764Recruiting
Registry of nerve-targeting heart treatment for fainting
This registry tracks people who receive a heart procedure called cardioneuroablation to stop severe fainting spells. The procedure targets nerve signals that cause the heart to pause, and researchers want to learn how well it works in real-world patients.
BronAges 18–100 - NCT06160310Recruiting
TSC & LAM Pregnancy Registry Study
This study is a registry that gathers information from pregnant women with Tuberous Sclerosis Complex (TSC) or Lymphangioleiomyomatosis (LAM), as well as infants born to them. The goal is to better understand how these conditions affect pregnancy and the baby's health.
Cincinnati, OhioAges Any age - NCT06161376Recruiting
Urine test for bladder problems in multiple sclerosis
This study looks at a substance in urine (called S1P) to see if it can help doctors find bladder overactivity in people with multiple sclerosis. If successful, this test could simplify diagnosis and avoid more invasive procedures.
ToulouseAges 18–75 - NCT06161636Recruiting
Studying hand movement to diagnose Parkinson's early
This trial looks at how analyzing hand movements might help doctors tell the difference between Parkinson's disease and other similar conditions early on. It may help improve diagnosis so patients get the right care sooner.
Montreal, QuebecAges 50–75 - NCT06161974RecruitingPhase 2
Olutasidenib and temozolomide for IDH1-mutant high-grade glioma
This trial tests a combination of two oral medications, olutasidenib and temozolomide, for people with a specific type of aggressive brain tumor (high-grade glioma) that has an IDH1 mutation. The goal is to see if this combination can help control the tumor after standard treatment like radiation.
Aurora, ColoradoAges 12–39 - NCT06162091Recruiting
Understanding recovery after severe brain injury
This study is for adults who recently had a severe brain injury (within the last 3 months) and are in the early stages of recovery. Researchers want to learn more about what affects recovery and how to improve outcomes.
MessinaAges 18 years+ - NCT06162013RecruitingPhase 2
NAD supplement trial for atypical parkinsonism
This trial tests whether a supplement called nicotinamide riboside (NR) can help people with rare forms of parkinsonism (PSP, MSA, or CBS). It is a double-blind study, meaning neither you nor the doctors will know if you are getting the real supplement or a placebo.
Oslo, OsloAges 30–85 - NCT06162338Recruiting
Study of LY-M001 for Gaucher Disease Type I
This study tests an injection called LY-M001 for adults with Gaucher disease type I. The goal is to see if it can safely help replace the missing enzyme and improve symptoms.
Hanzhou, ZhejiangAges 18–60 - NCT06163469Recruiting
Chlorhexidine bladder wash for people with long-term suprapubic catheters
This study tests whether washing the bladder with a solution called chlorhexidine (a germ-killer) can lower the number of unplanned hospital visits and improve quality of life for people who have a long-term suprapubic catheter. You may be eligible if you have had a catheter for at least a year and have had a recent urinary tract infection.
New Haven, ConnecticutAges 18 years+ - NCT06163547Recruiting
Brain artery treatment for chronic subdural hematoma
This study tests a new way to treat chronic subdural hematomas (a type of bleeding on the brain) by using a very thin tube to seal off a small artery inside the head. This may help the blood clot shrink without needing a traditional surgery.
GenevaAges 18–100 - NCT06164314Recruiting
Calming medicine during brain tumor surgery
This trial tests if a calming medicine (dexmedetomidine) given during and after brain tumor surgery can help prevent confusion or delirium afterwards.
BeijingAges 18 years+ - NCT06164262Recruiting
Dementia risk study for people with small vessel disease
This study tracks people ages 30 to 60 who have signs of small vessel disease on brain MRI. It aims to understand the risk of dementia over the next 10 years, so you can get early monitoring and care.
Hangzhou, ZhejiangAges 30–60 - NCT06164483Recruiting
Hearing tests in people with MS or Parkinson's
This study checks how well people with multiple sclerosis (MS) or Parkinson's disease hear. It uses simple hearing tests to see if these conditions affect hearing.
Catania, SicilyAges 20–40 - NCT06165653Recruiting
Guided meditation during radiation for brain tumors
This trial tests whether guided meditation can help people with brain tumors feel better during radiation therapy. You'll be randomly assigned to either meditation sessions or standard care, and researchers will see how it affects your well-being.
Salt Lake City, UtahAges 18 years+ - NCT06166277Recruiting
Ablation for fainting and slow heartbeat registry
This study tests a procedure called cardioneuroablation for people whose fainting or very slow heartbeat doesn't improve with other treatments. If you are under 60, have no other major heart conditions, and have not had ablation before, it might be an option to reduce or stop your fainting spells.
Chicago, IllinoisAges 18–60 - NCT06167330Recruiting
Titan trial: Reducing phantom limb pain
This trial tests a new method to reduce phantom limb pain (pain felt in a missing limb) using gentle electrical stimulation and simple mental exercises. It is for people with one-sided amputations who have had phantom limb pain for at least three months and still have pain episodes now.
Randwick, New South WalesAges 18 years+ - NCT06167239Recruiting
Breathing muscle training for Guillain-Barre patients on ventilators
This trial compares two methods to help people with Guillain-Barre syndrome who are having trouble breathing on their own after being on a ventilator. It tests if adjusting the ventilator's sensitivity or doing specific breathing muscle exercises can improve blood oxygen levels and help them wean off the machine.
CairoAges 20–55 - NCT06167369Recruiting
Sleep apnea, brain health, and CPAP therapy study
This study looks at how sleep apnea affects your brain and thinking skills. Researchers want to see if CPAP treatment can help protect your brain health.
Dresden, SaxonyAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,435 recruiting neurology studies from the U.S. registry right now, out of 19,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.