Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,435 recruiting studies in this area right now.
By phase
- Not applicable9,772
- Phase 2786
- Phase 1573
- Phase 3535
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3123
Top conditions
- Stroke846
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California680
- Massachusetts300
- New York291
- Florida274
- Texas268
- Maryland245
- Arizona214
- Alabama209
- Illinois190
- Pennsylvania177
Recruiting studies12,433 total
- NCT06332404Recruiting
Sleep apnea nerve stimulation therapy registry
This study is tracking how well a nerve stimulation device works for people with obstructive sleep apnea who can't use a CPAP machine. The device, called Inspire, sends mild electrical pulses to help keep your airway open while you sleep.
Edegem, AntwerpAges 18–99 - NCT06332807RecruitingPhase 1/Phase 2
Gene therapy trial for classic PKU
This trial tests a one-time gene therapy called NGGT002 for adults with classic PKU who cannot take or do not respond well to current treatments. The goal is to see if it can safely lower blood phenylalanine levels.
Orange, CaliforniaAges 18–55 - NCT06332989Recruiting
Improving stroke triage by ambulance paramedics
This trial tests a new way for paramedics to quickly identify and prioritize stroke patients before they reach the hospital, which could help get you the right treatment faster.
LeidenAges 18 years+ - NCT06333392Recruiting
Underwater colonoscopy for better cancer screening
This trial tests if a new type of colonoscopy called total underwater colonoscopy (TUC) is better at finding polyps and cancer during routine screening. If you had a positive FIT stool test and are scheduled for a follow-up colonoscopy, you may be able to join.
DrammenAges 55–60 - NCT06333899RecruitingEarly Phase 1
Lorlatinib for newly diagnosed brain tumors with ROS or ALK fusion
This trial tests if lorlatinib, a targeted pill, can shrink or slow the growth of high-grade brain tumors that have a specific ROS or ALK genetic change. It is for children and young adults who have not yet had treatment for their tumor.
Aurora, ColoradoAges 1–21 - NCT06334601Recruiting
Sleep apnea test to measure airway collapse and muscle response
This study looks at how the upper airway collapses and how muscles respond in people with obstructive sleep apnea (OSA) during sleep. It may help researchers understand why some treatments work better for some people.
MilanAges 18 years+ - NCT06333990RecruitingPhase 3
Quetiapine for concussion symptoms in veterans
This study tests whether quetiapine (a medication that can help with mood, sleep, and thinking) reduces ongoing concussion symptoms in veterans who had a mild traumatic brain injury (mTBI) at least 6 months ago. You may join if you are already taking at least three medications for your brain or mental health symptoms and have some PTSD symptoms.
Albuquerque, New MexicoAges 18–65 - NCT06334029Recruiting
Observing brain connections in epilepsy
This study is observing how the brain's connections and activity work in people with epilepsy. It uses MRI scans and EEG recordings to learn more about the condition, which may help improve future treatments.
Conegliano, TrevisoAges 6–65 - NCT06334952Recruiting
Personalized brain stimulation for hard-to-treat epilepsy
This study tests a personalized, non-invasive brain stimulation method called tDCS for people with drug-resistant epilepsy that starts in one part of the brain. It aims to reduce seizures in those who cannot have surgery or have not been helped by surgery.
BordeauxAges 9 years+ - NCT06334640Recruiting
Sleep quality and chronic eye diseases
This study looks at how sleep quality affects people with macular degeneration or glaucoma compared to healthy volunteers. It may help find links between sleep and eye health.
MilanAges 18 years+ - NCT06335784Recruiting
Mental imagery and memory reactivation for insomnia
This study tests whether combining mental imagery with a technique called targeted memory reactivation can improve sleep in people with insomnia. It's a non-drug approach that may help you fall asleep faster and stay asleep longer.
GenevaAges 18–45 - NCT06335836Recruiting
Social connections and brain health in memory decline
This study looks at how being socially isolated or socially active affects memory and brain health in people who feel their thinking is getting worse. You may join if you notice a slow decline in memory or thinking, but otherwise have normal test results.
Nanjing, China, JiangsuAges 45–85 - NCT06335719Recruiting
Electrical stimulation during nerve grafting for facial paralysis
This trial tests whether using gentle electrical stimulation during surgery can improve the results of nerve grafting for people with facial paralysis on one side. It's for patients who are already planning a two-stage surgery to restore their smile.
Cleveland, OhioAges 18–80 - NCT06336031Recruiting
Blood fear and fainting study
This study looks at how a fear of blood or needles affects fainting. You will be asked to watch or experience something related to blood or needles while your body's responses are measured.
Burnaby, British ColumbiaAges 18–50 - NCT06335888RecruitingPhase 2
Testing a new imaging agent for large vessel vasculitis
This study tests a special radioactive tracer, 18F-AzaFol, to see if it can help diagnose large vessel vasculitis, a type of inflammation in the arteries. The results will be compared with standard FDG PET/CT scans.
BernAges 50 years+ - NCT06336070Recruiting
Power training for metabolic health in postmenopausal cancer survivors
This trial compares two types of exercise—muscle power training and metabolic power training—to see which better improves your body's ability to use energy and control heart function. You may qualify if you are a postmenopausal woman who has had breast cancer and is not currently active.
Valencia, ValenciaAges 35–75 - NCT06336174Recruiting
Thinking and Memory in Brain Artery Narrowing: A Study
This study looks at how severe narrowing of brain arteries may affect memory and thinking over time. It involves people who have had a mini-stroke or mild stroke and aims to understand the changes in cognitive function.
Hefei, AnhuiAges 18–80 - NCT06337188Recruiting
Adaptive communication device for severe motor impairments
This study tests a new wearable communication device that you can control with your head, hand, or foot. It may help people who have trouble speaking or typing due to conditions like spinal cord injury, stroke, or cerebral palsy.
Omaha, NebraskaAges 6 years+ - NCT06337149Recruiting
Breathing and attention in children with Ondine syndrome
This study looks at how breathing affects attention in children with Ondine syndrome, also known as Congenital Central Hypoventilation Syndrome (CCHS). It aims to understand if children with this condition have changes in attention and how those relate to their breathing patterns, helping doctors plan better care.
ParisAges 6–16 - NCT06337357Recruiting
Strength training for older adults with diabetes and muscle loss
This trial tests whether a specific strength-training program (called progressive resistance training) can help older adults with both type 2 diabetes and sarcopenia (muscle loss) improve muscle strength and overall function.
HanoiAges 60–80 - NCT06337201Recruiting
Digital life stories for dementia care
This trial tests a digital tool to create life stories for older adults with dementia. It aims to help healthcare workers provide more personalized care.
Karlskrona, Blekinge CountyAges 18 years+ - NCT06337578Recruiting
Telephone-based cognitive screening study
This study tests if a phone-based cognitive screening can effectively assess thinking and memory. It may help people who can't easily visit a clinic.
MilanAges 18–100 - NCT06337864Recruiting
Large neutral amino acids for adults with classical PKU
This study tests whether a specific mix of large neutral amino acids (LNAAs) can help adults with classical PKU by lowering phenylalanine levels in the brain. It includes an MRI and PET scan to see how the treatment affects brain activity.
CopenhagenAges 18–50 - NCT06337942Recruiting
Bladder or kidney-bladder transplant from a deceased donor
This trial offers a first-in-human transplant of a bladder or a kidney combined with a bladder from a deceased donor. It is for people with severe bladder problems or bladder cancer who already need a new bladder or are on immune-suppressing medicines for a prior organ transplant.
Los Angeles, CaliforniaAges 18–70
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,435 recruiting neurology studies from the U.S. registry right now, out of 19,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.