Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,435 recruiting studies in this area right now.
By phase
- Not applicable9,772
- Phase 2786
- Phase 1573
- Phase 3535
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3123
Top conditions
- Stroke846
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California680
- Massachusetts300
- New York291
- Florida274
- Texas268
- Maryland245
- Arizona214
- Alabama209
- Illinois190
- Pennsylvania177
Recruiting studies12,433 total
- NCT07694921Enrolling by invitation
Non-invasive brain stimulation for Alzheimer's disease
This trial tests if a safe, non-invasive electrical stimulation can help people with Alzheimer's disease. It aims to improve thinking and memory skills.
Hangzhou, ZhejiangAges 60 years+ - NCT07049003RecruitingPhase 1
Deep brain stimulation for severe tremor
This trial tests a new type of deep brain stimulation (DBS) for people with severe tremor from essential tremor, multiple sclerosis, or cerebellar conditions who haven't improved with standard treatments. It targets a different brain area to see if it can reduce shaking and improve daily activities.
Cleveland, OhioAges 21 years+ - NCT06649929Enrolling by invitationPhase 2
Better sleep for Latino couples and brain health
This study tests a program to help Latino couples improve sleep and CPAP use, which may lower Alzheimer's risk. You and your partner will join telehealth sessions together.
Tuscon, ArizonaAges 35 years+ - NCT05999084Enrolling by invitation
Georgia Memory Net Anti-Amyloid Antibody Study
This study tests antibody treatments that target amyloid plaques in the brain for people with mild memory or thinking problems. It may help determine if you are a candidate for these new drugs and monitors your safety through regular scans and checkups.
Albany, GeorgiaAges 50–90 - NCT07110337Recruiting
Diagnosing epilepsy to help guide treatment
This trial tests a new device to help diagnose epilepsy in people whose previous EEG brain monitoring did not give clear answers. If you have drug-resistant epilepsy with at least one seizure a month on average, this study may help find better treatment options.
Phoenix, ArizonaAges 18–75 - NCT07638462Recruiting
Early mobility recovery program after acute stroke
This study tests whether early movement and physical activity help stroke patients recover better mobility. You'd be in the hospital after a recent stroke, and the team would work with you on safe movement and exercises during your recovery.
Winston-Salem, North CarolinaAges 18 years+ - NCT06326190RecruitingPhase 2
Study of radioactive drug for recurrent meningioma
This trial tests a radioactive drug called 177Lu-DOTATATE for people with recurrent meningioma (a type of brain tumor) that has grown after surgery and radiation. The drug targets a protein on the tumor cells and delivers radiation directly to them.
InnsbruckAges 18 years+ - NCT06326424Recruiting
Delirium check for older dementia patients in the ER
This study tests a way to identify delirium (sudden confusion) in older adults with Alzheimer's or other dementias while they are in the emergency room or hospital. It may help doctors detect and treat confusion faster.
Columbus, OhioAges 65 years+ - NCT06327035Recruiting
Walking recovery after a recent stroke
This study follows how walking ability improves in people recovering from a recent stroke during their stay in a rehabilitation center. The goal is to better understand recovery patterns so therapy can be tailored.
Granville, NormandyAges 18 years+ - NCT06327594Recruiting
Muscle loss check in lung cancer surgery patients
This study looks at muscle loss (sarcopenia) in people with lung cancer who are about to have surgery. It uses a CT or MRI scan to check your muscle health, which may help doctors better plan your care.
Chengdu, SichuanAges 40–100 - NCT06328608RecruitingPhase 2/Phase 3
PRX-102 for children with Fabry disease
This study tests a new enzyme replacement therapy called PRX-102 for children with Fabry disease. It aims to see if the drug is safe and helps manage symptoms like pain and eye or skin changes.
Phoenix, ArizonaAges 2–17 - NCT06328686RecruitingEarly Phase 1
Arginine and whole brain radiation for brain metastases
This trial tests whether taking arginine (an amino acid) during whole brain radiation therapy can help people with brain metastases from any type of cancer. It looks at how the treatment affects the body and may improve outcomes.
Atlanta, GeorgiaAges 18 years+ - NCT06328712RecruitingPhase 1/Phase 2
Cell therapy for Charcot-Marie-Tooth type 1A (CMT1A)
This trial tests a new cell therapy called EN001 for people with CMT1A. It aims to see if the treatment is safe and can help with nerve function and muscle weakness.
GyeongjuAges 19 years+ - NCT06329453Recruiting
Gut immunity and brain health study
This study looks at how your gut's immune system relates to brain and nerve diseases. Researchers will collect samples during a colonoscopy to better understand connections between gut health and neurologic conditions like multiple sclerosis or Parkinson's disease.
North Haven, ConnecticutAges 18–99 - NCT06329635Recruiting
Nicardipine via spine tube for brain blood vessel spasm
This trial tests whether giving a medicine called nicardipine through a tube in the spine (intrathecal) helps prevent or treat blood vessel tightening that can happen after a brain aneurysm rupture. It is for people who have had a specific type of brain bleed and show signs of vessel spasm.
Hefei, AnhuiAges 18–80 - NCT06329570RecruitingPhase 1/Phase 2
Bevacizumab with focused ultrasound for recurrent glioblastoma
This trial tests whether adding a focused ultrasound system (NaviFUS) to the drug bevacizumab can help people whose glioblastoma has come back. The treatment aims to deliver the drug more precisely to the brain tumor and potentially improve outcomes.
Charlottesville, VirginiaAges 18 years+ - NCT06329726Recruiting
Thinking and memory after brain stimulation for Parkinson's
This study looks at how deep brain stimulation (DBS) affects thinking and memory in people with Parkinson's disease over time. It compares results from people who have DBS and those who receive only medication.
Milan, LombardyAges 18–70 - NCT06329739Recruiting
Genetics and thinking in Parkinson's disease
This study looks at how certain genes might affect thinking and behavior in people with Parkinson's disease. If you have Parkinson's, take Parkinson's medication, and have had genetic testing, you may be able to join.
MilanAges 18 years+ - NCT06330350Recruiting
Talking about family planning for genetic skin conditions
This study interviews people with inherited skin conditions (genodermatoses) who want to have children, and the doctors who care for them. The goal is to learn how to better support family planning decisions, like counseling about genetics and pregnancy risks.
Maastricht, LimburgAges Any age - NCT06330181Recruiting
Virtual walking therapy for spinal cord injury nerve pain
This study tests a new virtual reality walking therapy program designed to help people with incomplete spinal cord injury reduce nerve pain. If you use a wheelchair and have lasting nerve pain, this could be a way to try a non-drug treatment from home.
College Station, TexasAges 18 years+ - NCT06330818Recruiting
Imaging study for Moyamoya disease
This study tests different brain imaging methods (MRI and PET/CT) to better understand blood flow and disease activity in people with Moyamoya disease. The goal is to learn more about the condition and possibly find new ways to see how active the disease is.
Tübingen, Baden-WurttembergAges 18–80 - NCT06330870Recruiting
How breast cancer spreads to the brain
This study looks at how breast cancer spreads to the brain in people who had surgery to remove brain tumors. It helps doctors understand why some women get brain metastases.
SeoulAges Any age - NCT06330922Recruiting
Muscle and tendon health study in cerebral palsy
This study looks at muscle and tendon health in people with spastic cerebral palsy who are mildly to severely affected. It involves using a special running frame to see how it affects the body.
GrazAges 14–30 - NCT06331819Recruiting
Sleep apnea, facial pigmentation, and fainting study
This study looks at whether sleep apnea, facial pigmentation, and fainting symptoms are connected. It aims to help understand these conditions better.
AmmanAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,435 recruiting neurology studies from the U.S. registry right now, out of 19,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.