Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,435 recruiting studies in this area right now.
By phase
- Not applicable9,772
- Phase 2786
- Phase 1573
- Phase 3535
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3123
Top conditions
- Stroke846
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California680
- Massachusetts300
- New York291
- Florida274
- Texas268
- Maryland245
- Arizona214
- Alabama209
- Illinois190
- Pennsylvania177
Recruiting studies12,433 total
- NCT06338215Recruiting
Moderate drinking vs. abstention advice for adults
This study compares two approaches for adults who drink regularly: advice on drinking in moderation vs. advice to stop drinking entirely. The goal is to see which approach better prevents major diseases and early death over time.
Pamplona, NavarreAges 50–75 - NCT06338397Recruiting
Social and emotional thinking in Alzheimer's
This study looks at how Alzheimer's disease and similar conditions affect social and emotional thinking. Researchers will use brain scans and questionnaires to understand these changes better.
LilleAges 40–85 - NCT06338904Recruiting
Suicide prevention program for adults over 50
This trial tests a brief problem-solving program delivered in different formats to help adults over 50 who are having thoughts of suicide. The goal is to see which format works best to reduce suicidal thoughts.
Santiago de Compostela, A CoruñaAges 50 years+ - NCT06339580RecruitingPhase 2
Volume-targeted ventilation for neuromuscular disease
This trial tests a smarter ventilator setting that automatically adjusts pressure to deliver a steady amount of air. It may help people with slowly worsening muscle weakness who already use a nighttime breathing machine.
London, LondonAges 18–80 - NCT06339190Recruiting
Testing blood and voice for early dementia diagnosis
This study uses a simple blood test (neurofilament light chain) and a voice recording analysis to see if they can help diagnose dementia earlier. Researchers want to see if these markers can reliably detect brain changes in people with memory or thinking problems.
Box Hill, VictoriaAges Any age - NCT06339398Recruiting
Exercise dose and brain health in Parkinson's
This study looks at how different amounts of physical exercise affect brain chemicals, movement symptoms, and brain connections in people with Parkinson's disease. You would walk and do exercises while researchers track changes over time.
Cassino, FrosinoneAges 30–80 - NCT06339957Recruiting
Rheumatology diet study for arthritis and related conditions
This study looks at how diet affects people with different types of arthritis and related autoimmune conditions. If you are a UCF Health patient between 18 and 65, you may be able to help researchers learn more about which foods help or worsen symptoms.
Orlando, FloridaAges 18–65 - NCT06340633RecruitingPhase 2
Testing SPI-1005 with cochlear implant surgery
This trial tests an oral medication, SPI-1005, given to adults receiving a cochlear implant to see if it improves hearing outcomes. It may help people with moderate to profound hearing loss who are scheduled for implant surgery.
Iowa City, IowaAges 18 years+ - NCT06340685RecruitingPhase 1
Triheptanoin for children with PDC deficiency
This trial tests an oil called triheptanoin for children with a rare genetic condition (PDCD) that affects how their bodies use energy. The study aims to see if triheptanoin can help improve their health.
Pittsburgh, PennsylvaniaAges 1–17 - NCT06340789RecruitingPhase 2
Sodium Benzoate Added to Antipsychotics for Resistant Schizophrenia
This study tests whether adding a supplement called sodium benzoate to your current antipsychotic medication can improve symptoms in schizophrenia that hasn't responded well to standard treatments. Researchers will measure brain chemistry changes and symptom improvement over time.
Chiayi CityAges 20–55 - NCT06340893Recruiting
Exercise training for kids with language delays
This study tests whether exercise training can help children with developmental language disorder or typical development. It looks at how exercise may affect communication and thinking skills.
Milwaukee, WisconsinAges 5–9 - NCT06341179Recruiting
Does more sleep help children learn and manage weight?
This study tests whether helping children sleep longer each night can help them learn better and manage their weight. It is for children ages 6–12 who are above a healthy weight and sleep 9 hours or less per night.
CopenhagenAges 6–12 - NCT06341673Recruiting
Nerve stimulation for bladder symptoms in multiple sclerosis
This trial tests a nerve stimulation treatment (TTNS) to improve bladder symptoms like urgency or frequent urination in people with multiple sclerosis. It is a randomized controlled study comparing this approach to a control, and aims to see if it can reduce bothersome bladder issues.
Khobar, Eastern ProvidenceAges 18 years+ - NCT06342206Recruiting
TCM Assessment for Recent Ischemic Stroke
This study uses traditional Chinese medicine (TCM) diagnostic tools to evaluate patients who had an ischemic stroke within the last 10 days. It aims to understand the acute and chronic phases of stroke to help guide future treatments.
ChanghuaAges 20 years+ - NCT06342544RecruitingPhase 3
Steroids and rituximab to prevent myasthenia from spreading
This trial tests whether a combination of steroid medicine (corticosteroid) and a targeted immune drug (rituximab) can prevent mild eye-muscle weakness from spreading to other muscles. It is for people newly diagnosed with ocular myasthenia who have not yet taken immune-suppressing treatments.
BordeauxAges 18 years+ - NCT06342661Recruiting
VISTA protein in blood vessel-related memory problems
This study measures levels of a protein called VISTA in the blood of people with memory problems caused by blood vessel disease. It aims to see if VISTA can help diagnose or predict this condition.
Harbin, HeilongjiangAges 50–80 - NCT06343558Recruiting
Gait and balance study for rare neurological diseases
This study looks at how people with rare or common neurological diseases walk and keep their balance. You will be asked to do simple walking and standing tasks to help doctors understand these problems better.
Milan, MilanAges 18–80 - NCT06343688Recruiting
How ankle braces affect motor skills in CP
This study tests how wearing special ankle braces (called DAFOs) right away affects movement and balance in children with spastic diplegic cerebral palsy. It aims to see if the braces make it easier to walk and stand.
BoluAges 4–15 - NCT06344260RecruitingPhase 2
Neural stem cell therapy for ALS: a phase 2 trial
This trial tests whether injecting neural stem cells into the spine can slow down ALS. It is for people with rapidly progressing ALS who have good lung function and a caregiver to help with visits.
San Giovanni Rotondo, FoggiaAges 18–65 - NCT06344650Recruiting
Understanding bone strength in acromegaly
This study looks at what makes bones strong or weak in people with acromegaly (a condition that causes too much growth hormone). It aims to find better ways to check bone health and prevent fractures.
MilanAges 18 years+ - NCT06344871Recruiting
Testing a new head-only PET scanner
This study tests a new, more comfortable head-only PET scanner that may be easier for patients to use. You can join if you are already getting a routine brain PET scan.
LeipzigAges 18–80 - NCT06345547Recruiting
Muscle mass ultrasound study in cirrhosis patients
This study uses ultrasound to measure muscle mass in people with cirrhosis. It aims to understand muscle changes and their link to health outcomes.
Edegem, AntwerpenAges 18 years+ - NCT06345781Recruiting
Abdominal electrical stimulation for bowel management in spinal cord injury
This trial tests if a special electrical stimulation (FES) on your belly can help make your bowel routine more predictable and shorter. You'll use electrodes on your skin 30 minutes before your usual bowel program.
Englewood, ColoradoAges 18 years+ - NCT06345872Recruiting
Better sleep to help reduce opioid use for chronic pain
This study tests a sleep improvement program to help people with chronic widespread pain reduce or stop their opioid pain medication. If you want to cut back on opioids and have trouble sleeping, this treatment might be a good fit.
Tampa, FloridaAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,435 recruiting neurology studies from the U.S. registry right now, out of 19,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.