Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,431 recruiting studies in this area right now.
By phase
- Not applicable9,770
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2303
- Phase 2/Phase 3123
Top conditions
- Stroke846
- Parkinson Disease425
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke201
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California677
- Massachusetts300
- New York290
- Florida274
- Texas268
- Maryland245
- Arizona214
- Alabama209
- Illinois190
- Pennsylvania177
Recruiting studies12,429 total
- NCT06343558Recruiting
Gait and balance study for rare neurological diseases
This study looks at how people with rare or common neurological diseases walk and keep their balance. You will be asked to do simple walking and standing tasks to help doctors understand these problems better.
Milan, MilanAges 18–80 - NCT06343688Recruiting
How ankle braces affect motor skills in CP
This study tests how wearing special ankle braces (called DAFOs) right away affects movement and balance in children with spastic diplegic cerebral palsy. It aims to see if the braces make it easier to walk and stand.
BoluAges 4–15 - NCT06344260RecruitingPhase 2
Neural stem cell therapy for ALS: a phase 2 trial
This trial tests whether injecting neural stem cells into the spine can slow down ALS. It is for people with rapidly progressing ALS who have good lung function and a caregiver to help with visits.
San Giovanni Rotondo, FoggiaAges 18–65 - NCT06344650Recruiting
Understanding bone strength in acromegaly
This study looks at what makes bones strong or weak in people with acromegaly (a condition that causes too much growth hormone). It aims to find better ways to check bone health and prevent fractures.
MilanAges 18 years+ - NCT06344871Recruiting
Testing a new head-only PET scanner
This study tests a new, more comfortable head-only PET scanner that may be easier for patients to use. You can join if you are already getting a routine brain PET scan.
LeipzigAges 18–80 - NCT06345547Recruiting
Muscle mass ultrasound study in cirrhosis patients
This study uses ultrasound to measure muscle mass in people with cirrhosis. It aims to understand muscle changes and their link to health outcomes.
Edegem, AntwerpenAges 18 years+ - NCT06345781Recruiting
Abdominal electrical stimulation for bowel management in spinal cord injury
This trial tests if a special electrical stimulation (FES) on your belly can help make your bowel routine more predictable and shorter. You'll use electrodes on your skin 30 minutes before your usual bowel program.
Englewood, ColoradoAges 18 years+ - NCT06345872Recruiting
Better sleep to help reduce opioid use for chronic pain
This study tests a sleep improvement program to help people with chronic widespread pain reduce or stop their opioid pain medication. If you want to cut back on opioids and have trouble sleeping, this treatment might be a good fit.
Tampa, FloridaAges 18 years+ - NCT06346535Recruiting
PrimeCog: New thinking tests for recent depression or stress diagnosis
This trial studies new digital tests that could help doctors in primary care detect cognitive (thinking) problems in people recently diagnosed with depression or stress-related disorders. The goal is to find reliable early signs of cognitive changes so treatment can be better tailored.
Linköping, Östergötland CountyAges 18–65 - NCT06347276Recruiting
PFO closure and brain microemboli study
This trial looks at whether closing a small hole in the heart (PFO) can reduce tiny clots traveling to the brain. It includes people who have had a stroke or migraine, and also those without symptoms but with high-risk features.
Beijing, Beijing MunicipalityAges 18–65 - NCT06347718RecruitingPhase 1/Phase 2
Car-T cells for autoimmune disease
This study tests a type of immunotherapy called CAR-T cells for people with certain autoimmune diseases like lupus, scleroderma, or myositis. It aims to see if this treatment can help when standard medicines haven't worked well enough.
Erlangen, BavariaAges 18 years+ - NCT06347796Recruiting
Embolization vs surgery for chronic subdural hematoma
This trial compares a newer, less invasive treatment (embolization) with traditional surgery to treat chronic subdural hematoma (a slow bleed on the brain). It aims to see which approach works better and has fewer side effects.
Phoenix, ArizonaAges 40–90 - NCT06349148Recruiting
Nutrition therapy for advanced cervical cancer
This study tests whether a special nutrition plan (immunonutrition) helps people with advanced cervical cancer who are having chemoradiation. It is for those who are also malnourished.
BeijingAges 18 years+ - NCT06349434Recruiting
Powered arm brace for spinal cord injury recovery
This trial tests whether a powered wearable device (Myo-Pro) can help people with spinal cord injury improve arm and hand function for daily activities. It is designed for those who already have some arm movement and want to regain more independence.
West Orange, New JerseyAges 18–80 - NCT06350110RecruitingPhase 1/Phase 2
CAR T cells for lupus
This trial tests a new type of CAR T cell therapy for people with active lupus that has not responded to other treatments. It uses specially engineered cells to target and eliminate certain immune cells that are causing the disease, with the goal of reducing symptoms and preventing flare-ups.
Beijing, Beijing MunicipalityAges 18–90 - NCT06350292Recruiting
Sleep help for children with ODD and insomnia
This study tests a sleep program for children ages 8-12 who have Oppositional Defiant Disorder (ODD) and trouble sleeping. The program aims to improve sleep and reduce daytime problems like mood swings and trouble focusing.
Tampa, FloridaAges 8–12 - NCT06350617Recruiting
Personalized brain stimulation to improve walking in Parkinson's
This study tests a customized brain stimulation technique called rTMS to help people with Parkinson's disease walk better. It aims to boost your brain's natural reserves to improve mobility and daily function.
SeoulAges 50 years+ - NCT06351839Recruiting
Sleep better despite long-term pain
This trial tests a program to help people with chronic pain and insomnia sleep better. It focuses on combining pain management with sleep improvement strategies.
Tromsø, Troms CountyAges 18–75 - NCT06352710Recruiting
Tracking recovery after brain or spine surgery
This study uses a smartphone app to track how you recover after brain or spine surgery. It helps doctors understand how side effects affect your daily life, so they can improve care.
Sankt Gallen, St.GallenAges 18 years+ - NCT06353529RecruitingPhase 4
Pain management after pituitary tumor surgery
This study tests a nerve block (called sphenopalatine ganglion block) for pain relief after pituitary tumor surgery through the nose. It aims to see if this block helps manage pain and reduces the need for other pain medicines.
Hamilton, OntarioAges 18–100 - NCT06353620Recruiting
Brain connections study for certain epilepsies and genetic syndromes
This study uses MRI and a special EEG to understand brain connections in people with specific types of epilepsy or genetic conditions like Angelman syndrome and Dup15q. It may help find better ways to treat these conditions.
Conegliano, TrevisoAges 6–75 - NCT06354010Recruiting
Study of Early-Onset Hearing Loss Related to GJB2 Gene
This study looks at hearing loss that starts in early adulthood (after age 16) and is linked to a specific gene change (GJB2). Researchers want to understand how this type of hearing loss changes over time.
Tampa, FloridaAges 30–55 - NCT06354881Recruiting
Blood flow in the brain after lacunar stroke
This study looks at how well-controlled blood pressure and diabetes affect blood flow in the brain after a small type of stroke called lacunar stroke.
Leicester, LeicestershireAges 18 years+ - NCT06356207Recruiting
Measuring heart pause time in fainting during tilt table test
This study tests a new way to measure how long it takes for your heart to pause during a tilt table test, in people with reflex fainting spells. The results may help doctors decide if a pacemaker is right for you.
BolzanoAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,431 recruiting neurology studies from the U.S. registry right now, out of 19,507 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.