Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,432 recruiting studies in this area right now.
By phase
- Not applicable9,770
- Phase 2785
- Phase 1574
- Phase 3537
- Phase 4342
- Phase 1/Phase 2303
- Phase 2/Phase 3121
Top conditions
- Stroke846
- Parkinson Disease424
- Multiple Sclerosis343
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke200
- Epilepsy196
- Obstructive Sleep Apnea155
- Insomnia153
- Spinal Cord Injuries153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke141
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University126
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California674
- Massachusetts300
- New York291
- Florida274
- Texas267
- Maryland245
- Arizona214
- Alabama209
- Illinois190
- Pennsylvania177
Recruiting studies12,430 total
- NCT06347718RecruitingPhase 1/Phase 2
Car-T cells for autoimmune disease
This study tests a type of immunotherapy called CAR-T cells for people with certain autoimmune diseases like lupus, scleroderma, or myositis. It aims to see if this treatment can help when standard medicines haven't worked well enough.
Erlangen, BavariaAges 18 years+ - NCT06347796Recruiting
Embolization vs surgery for chronic subdural hematoma
This trial compares a newer, less invasive treatment (embolization) with traditional surgery to treat chronic subdural hematoma (a slow bleed on the brain). It aims to see which approach works better and has fewer side effects.
Phoenix, ArizonaAges 40–90 - NCT06349148Recruiting
Nutrition therapy for advanced cervical cancer
This study tests whether a special nutrition plan (immunonutrition) helps people with advanced cervical cancer who are having chemoradiation. It is for those who are also malnourished.
BeijingAges 18 years+ - NCT06349434Recruiting
Powered arm brace for spinal cord injury recovery
This trial tests whether a powered wearable device (Myo-Pro) can help people with spinal cord injury improve arm and hand function for daily activities. It is designed for those who already have some arm movement and want to regain more independence.
West Orange, New JerseyAges 18–80 - NCT06350110RecruitingPhase 1/Phase 2
CAR T cells for lupus
This trial tests a new type of CAR T cell therapy for people with active lupus that has not responded to other treatments. It uses specially engineered cells to target and eliminate certain immune cells that are causing the disease, with the goal of reducing symptoms and preventing flare-ups.
Beijing, Beijing MunicipalityAges 18–90 - NCT06350292Recruiting
Sleep help for children with ODD and insomnia
This study tests a sleep program for children ages 8-12 who have Oppositional Defiant Disorder (ODD) and trouble sleeping. The program aims to improve sleep and reduce daytime problems like mood swings and trouble focusing.
Tampa, FloridaAges 8–12 - NCT06350617Recruiting
Personalized brain stimulation to improve walking in Parkinson's
This study tests a customized brain stimulation technique called rTMS to help people with Parkinson's disease walk better. It aims to boost your brain's natural reserves to improve mobility and daily function.
SeoulAges 50 years+ - NCT06351839Recruiting
Sleep better despite long-term pain
This trial tests a program to help people with chronic pain and insomnia sleep better. It focuses on combining pain management with sleep improvement strategies.
Tromsø, Troms CountyAges 18–75 - NCT06352710Recruiting
Tracking recovery after brain or spine surgery
This study uses a smartphone app to track how you recover after brain or spine surgery. It helps doctors understand how side effects affect your daily life, so they can improve care.
Sankt Gallen, St.GallenAges 18 years+ - NCT06353529RecruitingPhase 4
Pain management after pituitary tumor surgery
This study tests a nerve block (called sphenopalatine ganglion block) for pain relief after pituitary tumor surgery through the nose. It aims to see if this block helps manage pain and reduces the need for other pain medicines.
Hamilton, OntarioAges 18–100 - NCT06353620Recruiting
Brain connections study for certain epilepsies and genetic syndromes
This study uses MRI and a special EEG to understand brain connections in people with specific types of epilepsy or genetic conditions like Angelman syndrome and Dup15q. It may help find better ways to treat these conditions.
Conegliano, TrevisoAges 6–75 - NCT06354010Recruiting
Study of Early-Onset Hearing Loss Related to GJB2 Gene
This study looks at hearing loss that starts in early adulthood (after age 16) and is linked to a specific gene change (GJB2). Researchers want to understand how this type of hearing loss changes over time.
Tampa, FloridaAges 30–55 - NCT06354881Recruiting
Blood flow in the brain after lacunar stroke
This study looks at how well-controlled blood pressure and diabetes affect blood flow in the brain after a small type of stroke called lacunar stroke.
Leicester, LeicestershireAges 18 years+ - NCT06356207Recruiting
Measuring heart pause time in fainting during tilt table test
This study tests a new way to measure how long it takes for your heart to pause during a tilt table test, in people with reflex fainting spells. The results may help doctors decide if a pacemaker is right for you.
BolzanoAges 18 years+ - NCT06356662RecruitingPhase 1
Testing tenofovir for Parkinson's disease
This trial is testing if a medicine called tenofovir, usually used for HIV and hepatitis B, can help people with early-stage Parkinson's disease. It's for people who are under 65 and have no other major health issues.
Hangzhou, ZhejiangAges 18–65 - NCT06357260Recruiting
Adding pregabalin to carbamazepine for trigeminal neuralgia
This trial tests whether adding pregabalin to your usual carbamazepine treatment can better control trigeminal neuralgia pain. It is for people with classic trigeminal neuralgia who want to see if a combination of medicines can help.
Rohtak, HaryanaAges 25–80 - NCT06357702Recruiting
Physical Self-Regulation vs Placebo for Chronic Jaw Pain
This study tests whether a physical self-regulation treatment (like relaxation or biofeedback) can help reduce chronic jaw muscle pain. It compares the treatment to a placebo (inactive) version to see if it works better.
Lexington, KentuckyAges 18 years+ - NCT06358495Recruiting
Sleep improvement to prevent depression and anxiety in teens
This study tests if improving sleep can help prevent depression and anxiety in teens who are at higher risk because a parent has had depression or anxiety. It's for teens who have trouble sleeping but don't have a history of depression or anxiety themselves.
Calgary, AlbertaAges 12–18 - NCT06358209Recruiting
Washing the brain for infection treatment
This study tests whether washing out the infected fluid spaces in the brain (ventricular irrigation) can safely treat a serious brain infection (ventriculitis). It is for adults with a confirmed infection and fever who are stable enough for the procedure.
Hefei, AnhuiAges 18–65 - NCT06358313RecruitingPhase 3
Clopidogrel with statins for small vessel stroke
This study tests if combining the blood thinner clopidogrel with either atorvastatin or rosuvastatin (both cholesterol-lowering drugs) works better for people who have had a mild first-time stroke in the small blood vessels of the brain. The goal is to find a safe and effective treatment regimen.
Kafr ash ShaykhAges 18–75 - NCT06358898Recruiting
Digital sleep and mood program for teens with depression
This trial tests a digital program that uses a smartphone app to help teens with both insomnia and depression. It combines a mood tracker with cognitive behavioral therapy for insomnia (CBT-I) to improve sleep and mood.
Shatin, New TerritoriesAges 12–18 - NCT06359782RecruitingPhase 2
Testing C1-inhibitor for brain bleed after aneurysm
This trial tests a drug called C1-inhibitor (a protein that calms inflammation) given shortly after a bleeding stroke caused by an aneurysm. The goal is to see if it can reduce brain damage and improve recovery.
The Hague, South HollandAges 18 years+ - NCT06359808Recruiting
Sleep Problems in Ulcerative Colitis Patients
This study looks at sleep problems in people with ulcerative colitis (a type of inflammatory bowel disease). It aims to understand how sleep affects your condition and may help find better ways to manage both.
Xi'an, ShaanxiAges 18–65 - NCT06360120RecruitingPhase 3
Clopidogrel plus a statin for large-vessel stroke recovery
This study tests whether adding clopidogrel (a blood thinner) to atorvastatin or rosuvastatin (cholesterol-lowering drugs) helps people who had a first-time large-vessel ischemic stroke. It aims to find the best way to prevent another stroke.
Kafr ash ShaykhAges 18–75
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,432 recruiting neurology studies from the U.S. registry right now, out of 19,532 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.