Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,462 recruiting studies in this area right now.
By phase
- Not applicable9,797
- Phase 2786
- Phase 1574
- Phase 3538
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3121
Top conditions
- Stroke854
- Parkinson Disease424
- Multiple Sclerosis342
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke199
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury152
- Sarcopenia148
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Pain Management114
- Migraine113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- Cairo University63
Where studies are running
- California675
- Massachusetts301
- New York292
- Florida277
- Texas267
- Maryland244
- Arizona216
- Alabama211
- Illinois193
- Pennsylvania177
Recruiting studies12,460 total
- NCT06564779Recruiting
New memory test for mild memory problems
This study is developing a new memory test for people with mild memory problems. It aims to better detect early changes in memory that might lead to Alzheimer's disease.
ToursAges 50 years+ - NCT06564987RecruitingPhase 1
Risk of nerve damage from numbing shots for dental work
This study looks at whether a common numbing shot for dental procedures can cause nerve damage. It may help dentists choose safer ways to numb your teeth.
Akron, OhioAges 18–55 - NCT06565143Recruiting
Brain stimulation for early Alzheimer's disease
This trial tests whether a gentle, non-invasive electrical brain stimulation method called tACS can help people in the early stages of Alzheimer's disease. You may be eligible if you have mild cognitive impairment or early dementia and have been on a common Alzheimer's medication for at least 3 months.
Hefei, AnhuiAges 50–85 - NCT06565169Recruiting
Helping primary care doctors support advance care planning for dementia
This study tests a training tool to help primary care teams talk about future care wishes with people who have Alzheimer's or related dementias. It aims to improve advance care planning for older adults with dementia.
Chapel Hill, North CarolinaAges 18–99 - NCT06566066Recruiting
Thyroid hormone resistance patient registry
This study creates a registry for people with thyroid hormone resistance caused by specific genetic mutations. It helps doctors collect data to better understand and treat the condition.
BerlinAges Any age - NCT06566170Recruiting
Donanemab for early Alzheimer's: a real-world study
This study compares donanemab plus usual care to usual care alone for people with early Alzheimer's symptoms, to see how well donanemab works in everyday life. You may be able to join if you have early memory or thinking problems and have a brain scan or blood test showing Alzheimer's-related changes.
Huntsville, AlabamaAges 60 years+ - NCT06566521Recruiting
Nerve block for daytime laparoscopic adrenal tumor removal
This trial tests if a nerve block can help manage pain during surgery to remove a non-cancerous adrenal tumor. It may lead to a faster recovery and less nausea after the procedure.
Taiyuan, ShanxiAges 18–70 - NCT06566651Recruiting
Emotion processing study for people with ALS
This study looks at how people with ALS process emotions. It compares ALS patients, people with other nerve-muscle diseases, and healthy volunteers to understand changes in emotional processing.
Aarhus, Central JutlandAges 18 years+ - NCT06567197Recruiting
MS treatment with stem cell transplant in the Netherlands
This trial studies a stem cell transplant treatment for relapsing-remitting multiple sclerosis (RRMS). It aims to see how well this therapy works for people in the Netherlands who have already been approved for it.
AmsterdamAges 18–65 - NCT06567210Recruiting
Insomnia treatment and emotional memory regulation for mental health
This study tests whether treating insomnia can help regulate emotional memories overnight, which may reduce the risk of developing or worsening mental health conditions. You may be eligible if you have both insomnia and some anxiety symptoms.
Macquarie Park, New South WalesAges 18–45 - NCT06567431Recruiting
Blood and tears in alzheimer's disease
This study looks at different fluids from the body, like blood and tears, to find better ways to diagnose and track alzheimer's and related dementias. It compares people with these conditions to healthy volunteers to see what biological markers differ.
CopenhagenAges 30 years+ - NCT06567795Recruiting
Monitoring heart risk with a wearable sensor in diabetes
This trial tests a wearable chest sensor (called HEMOTAG) to monitor heart events in people with long-standing Type 2 diabetes who also have heart disease or specific diabetes-related complications. The sensor is worn at home for short periods to catch early signs of heart trouble, aiming to improve personalized care.
West Palm Beach, FloridaAges 40 years+ - NCT06568107Recruiting
Sensory and environment trial for dementia with repeated vocalizations
This study tests whether a calming environment and gentle sensory activities (like soothing sounds or textures) can help nursing home residents with dementia who make repeated sounds or cries. The goal is to see if these interventions can reduce those vocalizations and improve well-being.
Philadelphia, PennsylvaniaAges 50 years+ - NCT06567886Recruiting
Fibromyalgia Sleep Study: A to ZZZ
This study tests a sleep program for people with fibromyalgia. You can join from home through video calls, and the goal is to see if better sleep helps with fibromyalgia symptoms.
Ann Arbor, MichiganAges 18 years+ - NCT06568159Recruiting
Sleep apnea treatment in heart patients
This study looks at how well people with heart disease or high heart risk follow their sleep apnea treatment, comparing a mouth device (MAD) to a CPAP machine. It aims to find which treatment works better for daily use.
MontpellierAges 18 years+ - NCT06568185RecruitingPhase 2
Alpha lipoic acid and vitamin B for diabetic nerve damage
This trial tests whether a combination of alpha lipoic acid (a natural antioxidant) and vitamin B supplements can help relieve nerve pain, numbness, or tingling caused by diabetes. It is for people with type 2 diabetes who have diabetic nerve damage.
Kubang Kerian, KelantanAges 18 years+ - NCT06568536Recruiting
EEG Study to Predict Recovery After Brain Injury
This study uses a special EEG test to measure brain activity in people who are not fully conscious after a recent brain injury. The goal is to find better ways to know if someone will wake up and recover thinking abilities.
Boston, MassachusettsAges 18 years+ - NCT06568835Recruiting
Active exercise for hemodialysis patients
This study tests whether a program of regular, active exercise can help people on maintenance hemodialysis (a type of dialysis for kidney failure) feel better and improve their health. It's a chance to add gentle, supervised movement to your routine.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT06569121Recruiting
Telehealth weight-loss program for stroke survivors
This trial tests a 12-week telehealth group program to help people who have had a stroke lose weight and live healthier. You'll join video group meetings with a coach and other stroke survivors to learn about eating well and being active.
Dallas, TexasAges 18–85 - NCT06569472RecruitingPhase 1
CAR-T cell therapy for tough juvenile dermatomyositis
This trial tests a treatment using your own immune cells, modified to target a protein called CD19, for children and teens with juvenile dermatomyositis that hasn't gotten better with standard treatments. The goal is to see if this therapy can help calm the inflammation and improve symptoms.
Hangzhou, ZhejiangAges 5–17 - NCT06569550Recruiting
Fatigue treatment study for multiple sclerosis
This trial tests a brain stimulation therapy designed to reduce fatigue in people with multiple sclerosis. If you experience moderate to severe fatigue and have a stable medication routine, this study might help determine if a non-invasive treatment can improve your energy levels.
Hvidovre, Capital RegionAges 18–65 - NCT06569940Recruiting
Contactless sleep monitoring device vs standard monitors
This study compares a new contactless device (Sleepiz One+) to standard equipment that measures breathing and heart activity. It is for adults both with and without chronic health conditions.
Zurich, Canton of ZurichAges 18 years+ - NCT06570421Recruiting
Nerve stimulation for Parkinson's and essential tremor
This study tests a non-invasive nerve stimulation device for reducing tremors in people with Parkinson's disease or essential tremor. It follows up participants from a previous trial to see if benefits last up to 24 months.
OstravaAges 18 years+ - NCT06570616Recruiting
Reducing mask leaks during CPAP for sleep apnea
This study tests a method to help CPAP users with nasal masks who have high air leaks. It aims to find better ways to reduce unintentional leaking so treatment works more effectively.
São Paulo, BrazilAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,462 recruiting neurology studies from the U.S. registry right now, out of 19,649 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.