Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,934 recruiting studies in this area right now.
By phase
- Not applicable9,337
- Phase 2764
- Phase 1555
- Phase 3514
- Phase 4340
- Phase 1/Phase 2299
- Phase 2/Phase 3125
Top conditions
- Stroke797
- Parkinson Disease395
- Alzheimer Disease337
- Multiple Sclerosis330
- Dementia224
- Epilepsy192
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment126
- Cerebral Palsy119
- Pain Management113
- Migraine107
- Fibromyalgia105
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California655
- Massachusetts304
- New York295
- Florida267
- Texas267
- Maryland248
- Arizona209
- Alabama205
- Illinois183
- Pennsylvania175
Recruiting studies11,934 total
- NCT03774420Recruiting
Study of memory and thinking changes after breast surgery
This trial looks at whether certain anesthesia medications and airway devices are linked to short-term memory or thinking problems after breast surgery. If you’re having breast surgery under general anesthesia, your care team may compare outcomes to learn how to reduce “post-op cognitive dysfunction.”
Treviso, TVAges 18 years+ - NCT07406477RecruitingPhase 2
Heart support medication for newborns with brain injury
This trial tests whether adding a medication called dobutamine, which helps the heart pump, can improve recovery in newborns with HIE who are already receiving cooling treatment. It aims to see if this extra heart support can help babies recover better.
Edmonton, AlbertaAges 1 day–1 day - NCT04128670Recruiting
Kinesio tape test for sore muscles after exercise
This study checks whether Kinesio tape changes how sore your muscles feel after workouts. You may help researchers learn if the tape reduces “delayed onset muscle soreness” after upper-body activity.
Indianapolis, IndianaAges 18–30 - NCT07111065RecruitingPhase 2
Fatty Acid Supplement for Dermatomyositis
This study tests whether taking a fatty acid supplement (omega-3) for 6 months can help reduce disease activity in people with dermatomyositis. Participants will also receive dietary coaching and have regular check-ups at the NIH to monitor their progress.
Bethesda, MarylandAges 18–60 - NCT07091630RecruitingPhase 3
A study of empasiprubart for chronic inflammatory demyelinating polyneuropathy (CIDP)
This study tests a new medicine called Empasiprubart for adults with ongoing CIDP. It aims to see if fewer symptoms return and if it can replace current treatments.
Birmingham, AlabamaAges 18 years+ - NCT07405164RecruitingPhase 3
Long-term extension study for people taking belzutifan
This study is for people who are already taking belzutifan in a related trial (LITESPARK-043) and want to continue treatment for advanced solid tumors or von Hippel-Lindau-related conditions. It tests the safety and effects of long-term use.
Boston, MassachusettsAges 18 years+ - NCT07700225Recruiting
Long-term study of myotonic dystrophy type 1
This study is a long-term follow-up for people with myotonic dystrophy type 1. It aims to find better ways to measure how the disease progresses, which could help develop future treatments.
Richmond, VirginiaAges 18–70 - NCT07637669Recruiting
Smell and decision-making in people with HIV and substance use
This study looks at how smell and decision-making are affected in people living with HIV and/or substance use disorders. You may join one of four groups based on your HIV status and substance use history, and you will complete smell tests and computer tasks, with an optional MRI.
Baltimore, MarylandAges 18–65 - NCT07877766Enrolling by invitation
Microbiome study for patients having neck fusion surgery
This study looks at the bacteria in your body before and after neck surgery to see if they affect recovery. It may help improve care for future patients.
New York, New YorkAges 18–80 - NCT07867184Enrolling by invitation
Firefighter lung health study
This study looks at how firefighting affects your lungs over time. By tracking your health and exposures, researchers hope to find ways to prevent lung problems in firefighters.
Bethesda, MarylandAges 18–65 - NCT04965675RecruitingPhase 3
Eptinezumab for teens with chronic migraine
This trial tests eptinezumab, a preventive medicine, to reduce headache frequency in teens with chronic migraine. It may help your teen if they have frequent migraine days despite usual care.
New Haven, ConnecticutAges 12–17 - NCT07714980Recruiting
Acupoint stimulation timing for stomach cancer surgery recovery
This trial tests whether giving a gentle, needle-free acupoint stimulation before or after stomach cancer surgery helps speed up recovery. The stimulation uses a small device on the skin, similar to a tens unit, to support recovery after laparoscopic gastrectomy.
Dongying, ShandongAges 18–80 - NCT07796061RecruitingPhase 1
Ultrasound plus immune cells for brain tumors
This trial tests a new way to treat a type of brain tumor called diffuse midline glioma. It uses focused ultrasound to open a tiny gap in the blood-brain barrier, which may help special immune cells (T-cells) reach and attack the tumor. The goal is to see if this combination is safe and helpful.
Washington D.C., District of ColumbiaAges 3–25 - NCT07518810RecruitingPhase 2/Phase 3
Testing butylphthalide for multiple system atrophy
This study tests whether a drug called butylphthalide can safely help people with multiple system atrophy (MSA), a rare brain disorder that affects movement and automatic body functions like blood pressure. Participating may help slow the progression of symptoms and improve quality of life.
Nanning, GuangxiAges 30–80 - NCT07674654RecruitingPhase 3
Long-term safety study of an investigational migraine medication
This study is testing the long-term safety of an investigational migraine medication called elismetrep. It is for people who have already completed a previous study of this drug and are willing to continue using a smartphone app to track their symptoms daily.
Birmingham, AlabamaAges 18 years+ - NCT07505394Recruiting
Preventing impulse control side effects from Parkinson's medication
This study tests a computer-based tool that aims to predict and prevent impulse control disorders (like compulsive gambling or shopping) caused by certain Parkinson's medications. If you take a dopamine agonist, this tool might help your doctor adjust your treatment to avoid these side effects.
ParisAges 18 years+ - NCT05380856Recruiting
Sacral nerve stimulation for bladder, bowel, and sexual symptoms
This trial studies whether sacral neuromodulation (a device that sends mild nerve signals) can improve bladder, bowel, and sexual symptoms caused by nerve problems. It is for people whose current bladder treatments have not worked well enough.
Odense, FynAges 18–80 - NCT05615610Recruiting
Electrical stimulation therapy for brain and arm recovery after stroke
This trial tests whether painless electrical nerve stimulation placed on the skin can improve thinking (cognitive function) and arm movement in people living with long-term stroke. If you qualify, you may receive this non-drug therapy and be assessed for changes in memory/thinking and upper-limb movement.
Hong KongAges 50–80 - NCT07434986Recruiting
Overnight brain stimulation for temporal lobe epilepsy
This study tests whether a gentle magnetic device applied overnight can help reduce seizures in people with temporal lobe epilepsy. You'll stay in a sleep lab for one night while we monitor your brain waves and sleep.
Durham, North CarolinaAges 18–70 - NCT07546253Recruiting
Tracking outcomes for brain ablation in drug-resistant epilepsy
This trial is a registry that tracks real-world outcomes for people with drug-resistant epilepsy who are treated with the NeuroOne OneRF ablation system. Participants receive a standard procedure (RF ablation) and their health data is collected to help improve future care.
Miami, FloridaAges Any age - NCT05376267Recruiting
Testing how long cooling lasts after pediatric cardiac arrest
This study tests whether using body cooling for different lengths of time helps children recover better after an out-of-hospital cardiac arrest. It focuses on children who remain very unresponsive after resuscitation and need a breathing tube and steady temperature control.
Birmingham, AlabamaAges 2 days–17 years - NCT07249853RecruitingPhase 3
Cilostazol to prevent brain damage after aneurysm surgery
This trial tests if a medicine called cilostazol can reduce the risk of a delayed shortage of blood in the brain after having a bleeding aneurysm treated. It aims to improve recovery by preventing a common complication called delayed cerebral ischemia.
Beijing, Beijing MunicipalityAges 18–80 - NCT07860645Recruiting
Lifestyle program for menopause symptoms and sleep
This study tests whether a lifestyle program can help women in perimenopause or postmenopause feel better by reducing symptoms like hot flashes, sleep problems, and anxiety. If you join, you'll get support and be followed for 24 weeks to see if the program improves your quality of life.
Konya, KonyaAges 40–55 - NCT07099053Recruiting
Brain scan study for aging adults in Baltimore
This study uses a special brain scan (amyloid PET) to look at brain changes in healthy older adults. It may help researchers learn more about aging and memory loss.
Baltimore, MarylandAges 55–110
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,934 recruiting neurology studies from the U.S. registry right now, out of 18,325 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.