Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,462 recruiting studies in this area right now.
By phase
- Not applicable9,797
- Phase 2786
- Phase 1574
- Phase 3538
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3121
Top conditions
- Stroke854
- Parkinson Disease424
- Multiple Sclerosis342
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke199
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury152
- Sarcopenia148
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Pain Management114
- Migraine113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- Cairo University63
Where studies are running
- California675
- Massachusetts301
- New York292
- Florida277
- Texas267
- Maryland244
- Arizona216
- Alabama211
- Illinois193
- Pennsylvania177
Recruiting studies12,460 total
- NCT06705790Recruiting
Pelvic floor training for bladder, bowel, and sexual health after spinal cord injury
This study tests whether pelvic floor muscle exercises can improve bladder, bowel, and sexual function in people with a spinal cord injury. If you have ongoing symptoms in these areas and a stable health routine, this trial may help you learn ways to strengthen those muscles.
Vancouver, British ColumbiaAges 19 years+ - NCT06705816Recruiting
Cognitive function in Rett syndrome during trofinetide treatment
This study looks at how trofinetide (a medicine for Rett syndrome) affects thinking and memory in people with Rett syndrome. It will follow participants who are starting this treatment through a specific clinic.
Minneapolis, MinnesotaAges 18–99 - NCT06706284RecruitingPhase 4
GLP-1 agonist for diabetes after spinal cord injury
This trial tests whether a GLP-1 agonist (a type of diabetes medicine that also helps with weight loss) is safe and effective for people with spinal cord injury and type 2 diabetes who are not on other glucose-lowering drugs.
San Antonio, TexasAges 18–70 - NCT06706544RecruitingPhase 2/Phase 3
Ozone treatment for numbness or tingling after chemo
This trial tests whether ozone treatment (a gas therapy) can help relieve numbness or tingling caused by chemotherapy. It is for people whose cancer is stable or in remission and who have had these nerve symptoms for at least 3 months.
Las Palmas, Las PalmasAges 18 years+ - NCT06706687Recruiting
Brain imaging and epigenetics in frontotemporal dementia and bipolar disorder
This study uses brain scans and genetic tests to understand the differences between behavioral variant frontotemporal dementia (bvFTD) and bipolar disorder. It may help improve diagnosis and find better treatments for both conditions.
Milan, MIAges 18 years+ - NCT06707402Recruiting
Community walking program for people with Parkinson's
This study tests whether a 24-week community walking program (brisk walking) can help people with Parkinson's disease who have trouble walking. If you join, you will walk regularly with others in your community and have your walking ability checked before and after.
Aarhus CAges 40 years+ - NCT06707532Recruiting
Muscle relaxants for safer heart rhythm treatment
This study tests if giving muscle relaxants before a heart ablation procedure can protect muscles from damage. Ablation uses energy to fix irregular heartbeats, and muscle relaxants might make it safer.
Wroclaw, Lower Silesian VoivodeshipAges 18–90 - NCT06341023Recruiting
Balance training for older adults with MS
This study tests a balance training program for people with MS who have mild walking and memory difficulties. It aims to improve balance and prevent falls.
Chicago, IllinoisAges 18–90 - NCT04205279Recruiting
Balance training to help prevent falls
This study tests a reactive balance training program to reduce fall risk. It may help you improve how your balance reacts when you are pushed or lose stability.
Chicago, IllinoisAges 18–90 - NCT05283811Recruiting
Brain recording during epilepsy care, while doing a memory task
This study listens to brain activity in people with epilepsy who already need electrodes placed inside the brain. Researchers want to understand how different parts of the brain respond while you complete simple thinking and memory-related tasks, which may help improve future treatments.
Los Angeles, CaliforniaAges 10–64 - NCT04936620Recruiting
Surgery for severe neck spinal cord injury with uncontrolled swelling
This trial studies a specific surgical technique (called duroplasty) for people with a severe neck spinal cord injury who have dangerous swelling that is not controlled. The goal is to see if this approach can improve outcomes after emergency surgery done soon after the injury.
InnsbruckAges 16 years+ - NCT07685327Recruiting
Mixed reality vs. physical therapy for balance in teens with cerebral palsy
This study compares two types of therapy to help teens with spastic diplegic cerebral palsy improve their balance and coordination. One group will use mixed reality (a blend of real and virtual environments) and the other group will do standard physical therapy exercises.
Mansehra, KpkAges 10–19 - NCT05791604Recruiting
Study prebiotics and probiotics to help children with Prader-Willi
This trial studies whether taking prebiotics and probiotics can help children with Prader-Willi syndrome manage obesity. It’s testing a gut-focused approach to weight control over the study period.
Shanghai, Shanghai MunicipalityAges 3–10 - NCT07684053Recruiting
Digital screening for irregular heartbeat to prevent stroke
This study tests if using a digital device (like a smartwatch or phone) can help find an irregular heartbeat called atrial fibrillation. Finding it early may help prevent stroke, especially in people over 65.
Innsbruck, TyrolAges 65 years+ - NCT06008795RecruitingPhase 2
Pain-block injection for headache after brain bleed
This study tests a pain-block injection (called a PPF-block) for severe headaches after a brain bleed (subarachnoid hemorrhage). It compares the injection to standard pain medicine to see if it reduces headache and the need for opioids.
Gainesville, FloridaAges 18–85 - NCT06176833Recruiting
Walking therapy early after spinal cord injury
This study tests a special walking program for people who have recently had a spinal cord injury. The goal is to help you recover as much walking ability as possible.
Chicago, IllinoisAges 16–75 - NCT07688356RecruitingPhase 2
Belvarafenib for BRAF-altered brain tumors
This trial tests a drug called Belvarafenib for people with brain tumors that have a BRAF gene change (mutation). The drug targets this specific change to try to shrink or control the tumor. It is for patients whose brain tumor has come back or hasn't responded to other treatments.
SeoulAges 19 years+ - NCT06275698Recruiting
Honey for pain relief after tonsil removal
This trial tests whether taking honey after tonsil surgery helps reduce pain. If you are having both tonsils removed and are over 18, you may be able to join.
StevenageAges 18 years+ - NCT07685210RecruitingPhase 1
GenSci144 tablet safety study for healthy volunteers
This trial tests the safety of a new tablet called GenSci144 in healthy adults. It helps doctors see if the drug is safe and how the body handles it.
Jinan, ShandongAges 18–45 - NCT06549426Recruiting
Treating seizure activity after cardiac arrest
This trial tests a treatment for seizure-like brain activity that can happen after a cardiac arrest. It aims to see if treating these seizures quickly can improve recovery for people who are in a coma.
BrusselsAges 18 years+ - NCT05800639Recruiting
Testing brain-wave patterns during pediatric anesthesia awakening
This study looks at brain-wave activity (measured with sensors) in young children during and after general anesthesia for planned eye surgery. It may help doctors understand why some children become very upset or confused as they wake up.
SeoulAges 2–8 - NCT06100978Recruiting
Patient experiences after severe seizures
This study interviews people who had a severe, prolonged seizure (status epilepticus) and were treated in intensive care. It asks how they feel and what they experienced 3 months to 5 years later.
AngoulêmeAges 18 years+ - NCT04576793RecruitingPhase 2
Imaging brain inflammation in Alzheimer’s and related variants over time
This Phase 2 study uses repeated brain MRI scans to track “microglial activation,” which is a marker of brain immune/inflammation activity, in different Alzheimer’s-related conditions. It may help researchers understand how brain inflammation changes over time and differs between people with these clinical variants.
New York, New YorkAges 50 years+ - NCT05963568RecruitingPhase 3
Prevent more strokes with a daily anti-clotting heart pill
This Phase 3 trial tests whether a daily “polypill” can reduce the chance of another stroke after a recent ischemic stroke. It may help people by improving several heart-and-blood-vessel risks at once, but only if it fits safely with their medical situation.
ParakouAges 18–100
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,462 recruiting neurology studies from the U.S. registry right now, out of 19,649 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.