Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,465 recruiting studies in this area right now.
By phase
- Not applicable9,805
- Phase 2785
- Phase 1574
- Phase 3534
- Phase 4343
- Phase 1/Phase 2304
- Phase 2/Phase 3120
Top conditions
- Stroke856
- Parkinson Disease424
- Alzheimer Disease341
- Multiple Sclerosis341
- Dementia228
- Ischemic Stroke199
- Epilepsy195
- Obstructive Sleep Apnea154
- Spinal Cord Injuries153
- Traumatic Brain Injury153
- Insomnia152
- Sarcopenia149
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Migraine113
- Pain Management112
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota63
Where studies are running
- California673
- Massachusetts304
- New York293
- Florida278
- Texas268
- Maryland244
- Alabama213
- Arizona213
- Illinois193
- Pennsylvania177
Recruiting studies12,463 total
- NCT06925178Recruiting
Imaging database study for recent stroke patients
This study is building a standard imaging database for people who have recently had a stroke. By participating, you will help doctors better understand how to use different types of scans to diagnose and treat cerebrovascular disease.
Beijing, Beijing MunicipalityAges 18–80 - NCT06925269Recruiting
DMD Voice: Interviews with patients and caregivers
This study invites people with Duchenne muscular dystrophy (DMD) and their caregivers to share their experiences through interviews. It focuses on those who have been taking the medication Givinostat for at least two years, or caregivers of patients with limited arm movement.
Yardley, PennsylvaniaAges 10 years+ - NCT06925425Recruiting
Electrical stimulation for arm skills in children with cerebral palsy
This study tests if a special electrical stimulation therapy, used during specific tasks, can improve arm and hand control in children with spastic quadriplegic cerebral palsy. It aims to help kids with moderate to severe motor challenges gain better use of their upper limbs.
Alexandria, EgyptAges 2–6 - NCT06926010Recruiting
Blood flow monitoring for carotid artery surgery
This trial is testing a special way to monitor blood flow during carotid artery surgery to help keep patients safe. It may be a good fit if you are having planned carotid surgery and meet a few basic health criteria.
RomeAges 18 years+ - NCT06926036Recruiting
Sound therapy for sleep apnea
This study aims to test whether a special sound technique can help people with sleep apnea sleep better. It may offer a new way to manage the condition without needing a CPAP machine.
Chicago, IllinoisAges 18–60 - NCT06926348Recruiting
Testing a digital sleep aid for chronic insomnia
This study tests a digital sleep aid (a smartphone program) to see if it's easy to use and helps improve sleep. If you have chronic insomnia and own a compatible device, you may be able to join.
Verona, VeronaAges 18–70 - NCT06927206Recruiting
Vibration and muscle stimulation for leg function after stroke
This trial tests if adding a gentle vibrator to standard muscle-stimulation therapy can improve leg movement in people recovering from a stroke. It's for those who had a stroke 2 weeks to 3 months ago and have mild to moderate thinking and movement issues.
Lahore, Punjab ProvinceAges 45–60 - NCT06927284Recruiting
Thinking and robotic glove training for hand function after stroke
This trial tests if combining a soft robotic glove with thinking-based hand exercises helps stroke survivors regain hand movement better than exercises alone. If you had your first stroke 6 to 12 weeks ago and have some arm weakness, this study might be a fit.
Lahore, Punjab ProvinceAges 40–60 - NCT06928168Recruiting
Sleep extension to prevent sleep loss in active adults
This trial tests if sleeping more can help active people avoid the negative effects of not getting enough sleep. It might be a good fit if you exercise regularly and usually sleep 6 to 8 hours a night.
Saint-EtienneAges 18–50 - NCT06928298Recruiting
A cognitive screening study for Spanish speakers aged 60+
This study tests a new, easy-to-use cognitive screening tool on an iPad for older adults who speak Spanish. It aims to help primary care doctors detect thinking or memory changes early.
Austin, TexasAges 60 years+ - NCT06928519Recruiting
Entacapone with Madopar for early Parkinson's
This study tests whether adding entacapone to Madopar (a common Parkinson's medication) safely improves symptoms in people with early-stage Parkinson's. It aims to see if the combination works better than Madopar alone.
Nanning, GuanxiAges 18–80 - NCT06928649Recruiting
Studying cell damage in critically ill ICU patients
This trial looks at specific cell damage processes (called ferroptosis and pyroptosis) in very sick ICU patients. The goal is to learn more about these processes so doctors can better treat life-threatening organ failure caused by conditions like sepsis, trauma, or severe bleeding.
EdegemAges 18 years+ - NCT06928675Recruiting
Cell-free DNA in acute stroke
This study looks at how a substance called cell-free DNA in the blood changes in people with a large blood clot causing a stroke. It aims to improve understanding of this condition and might help with future treatments.
BaselAges 18 years+ - NCT06928727Recruiting
Eye health in craniosynostosis study
This study looks at eye features in people with craniosynostosis (a condition where skull bones fuse too early). It may help doctors better understand eye problems that can occur with this condition.
AmiensAges Any age - NCT06929572Recruiting
Umbilical cord patch for closing spine birth defects after birth
This trial tests using a patch made from a newborn's own umbilical cord to help close an open spine defect (myelomeningocele or myeloschisis) shortly after birth. The goal is to protect the spinal cord and improve healing.
Houston, TexasAges Up to 1 day - NCT06929598Recruiting
Shiatsu for chronic pain in children and teens
This study tests whether Shiatsu—a gentle, hands-on therapy—can help reduce chronic, non-inflammatory pain in children and adolescents. If you or your child have had long-term pain without inflammation and are already being seen at a specific pain clinic in Tel Aviv, this trial might be a good fit.
Tel Aviv, Tel AvivAges 10–18 - NCT06929923Recruiting
Pro-2-Cool study for concussion recovery
This trial tests a new treatment called Pro-2-Cool to see if it helps teenagers and young adults recover from a concussion. If you have bothersome symptoms and are otherwise healthy, this study may be a good fit.
Ann Arbor, MichiganAges 13–21 - NCT06930131Recruiting
Word-finding therapy with thinking skills training after stroke
This study tests a new talking therapy for people with word-finding problems after a stroke. It combines exercises to help you find words with training to think about how you learn and remember them.
ToulouseAges 18 years+ - NCT06930170Recruiting
Cochlear implant for children with hearing loss in one ear
This trial tests whether a cochlear implant helps children aged 4 to 6 years who have hearing loss in only one ear (or one ear with severe loss and the other with mild loss) improve their hearing and communication. The device is surgically placed in the ear with worse hearing.
ParisAges 4–6 - NCT06930261RecruitingPhase 2
Brain dopamine changes after traumatic coma
This study looks at how a traumatic brain injury that causes coma affects the brain's dopamine system. You will get two types of brain scans (MRI and PET) to see changes that might help predict recovery.
ToulouseAges 18–65 - NCT06930404Recruiting
New ways to diagnose sleep apnea
This study tests new ways to diagnose obstructive sleep apnea. If you haven't been diagnosed with sleep apnea and are generally healthy, you may be able to join.
Sydney, New South WalesAges 18 years+ - NCT06930560Recruiting
Hearing aids for dementia with mood or behavior issues
This study tests whether providing hearing aids to older adults with Alzheimer's or related dementias can reduce troubling symptoms like agitation or depression. If you have untreated hearing loss and a caregiver who can join you, this trial may help improve quality of life.
Baltimore, MarylandAges 60–100 - NCT06930417Recruiting
Williams syndrome and related 7q11.23 changes study
This study follows people with Williams syndrome, 7q11.23 duplication, or related genetic changes over time to understand how these conditions affect health and development. It also includes close family members to learn about the genetics.
Philadelphia, PennsylvaniaAges Any age - NCT06930586Recruiting
Metabolic brain imaging for rectal cancer prognosis
This trial studies how brain metabolism changes in people with rectal cancer and whether those changes can help predict outcomes. It uses a special type of PET imaging to look at brain activity.
Henan, HenanAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,465 recruiting neurology studies from the U.S. registry right now, out of 19,759 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.