Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,516 recruiting studies in this area right now.
By phase
- Not applicable9,855
- Phase 2786
- Phase 1573
- Phase 3533
- Phase 4344
- Phase 1/Phase 2305
- Phase 2/Phase 3120
Top conditions
- Stroke852
- Parkinson Disease423
- Alzheimer Disease341
- Multiple Sclerosis340
- Dementia230
- Ischemic Stroke202
- Epilepsy197
- Insomnia156
- Obstructive Sleep Apnea156
- Traumatic Brain Injury156
- Spinal Cord Injuries152
- Sarcopenia151
- Acute Ischemic Stroke141
- Cerebral Palsy129
- Mild Cognitive Impairment128
- Migraine112
- Pain Management112
- Amyotrophic Lateral Sclerosis106
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University127
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon80
- Johns Hopkins University71
- National Taiwan University Hospital71
- University of Minnesota65
Where studies are running
- California678
- Massachusetts307
- New York295
- Florida274
- Texas271
- Maryland245
- Alabama214
- Arizona209
- Illinois193
- Pennsylvania177
Recruiting studies12,514 total
- NCT06912841Enrolling by invitation
Deep brain stimulation for genetic movement disorders
This trial is for people of any age with a genetic movement disorder who are getting or considering deep brain stimulation (DBS). It tries to match the best DBS settings for each person.
Boston, MassachusettsAges Any age - NCT06912438Enrolling by invitation
Emotional release after dry needling for jaw and head pain
This study tests whether a dry needling technique (trigger point needling) can help release emotional tension and reduce pain from muscle knots in the head and neck. It may be a good option if you have jaw or headache pain related to muscle tightness.
Tel Aviv, IsraelAges 18 years+ - NCT06908850Enrolling by invitation
Understanding erogenous zones after spinal cord injury
This study explores how a complete spinal cord injury changes erogenous zones in adult men who are heterosexual and were sexually active before the injury. The goal is to better understand sexual response after injury.
GarchesAges 18 years+ - NCT06908473Enrolling by invitationPhase 3
Tongmai Jiangtang capsule for heart risks in metabolic syndrome
This trial tests whether the Tongmai Jiangtang capsule can reduce serious heart and stroke problems in older adults with metabolic syndrome who are also at high risk for heart disease. It focuses on people with a specific traditional Chinese medicine pattern called Qi-deficiency and Blood Stasis.
Guangzhou, GuangdongAges 65 years+ - NCT06906536Enrolling by invitation
Intermittent low oxygen to improve leg function after spinal injury
This trial tests whether short, controlled sessions of low oxygen (like breathing thin air) can improve leg movement and blood markers in people with spinal cord injuries. It may help with walking or standing.
Boulder, ColoradoAges 18–75 - NCT06904417Enrolling by invitationPhase 1
Feldenkrais method for balance in diabetic nerve pain
This trial tests whether a gentle movement technique called Feldenkrais can help people with diabetic nerve damage improve their balance and control. It may be an option if you have stable blood sugar and can walk on your own.
Cairo, Cairo GovernorateAges 45–60 - NCT06901310Enrolling by invitation
Hyperbaric oxygen for mild head injuries in combat athletes
This study tests whether hyperbaric oxygen therapy (breathing pure oxygen in a special chamber) helps men recover from mild head injuries better than the current standard care (rest). It is for male unarmed combat athletes who have been suspended for a head injury.
Marshfield, WisconsinAges 18 years+ - NCT06900244Enrolling by invitation
Metabolic Imaging for MS and Stroke
This study uses a special type of MRI scan to look at how energy is used in the brain. It may help researchers better understand neurological diseases like multiple sclerosis (MS) and stroke.
OxfordAges Up to 99 years - NCT06894927Enrolling by invitation
Hearing check for adults 50 and over
This trial offers a free hearing check for adults aged 50 and older. It aims to detect any hearing changes early and can help you understand your hearing health better.
Hradec Králové, Czech RepublicAges 50 years+ - NCT06891053Enrolling by invitation
Study of alexithymia and chronic migraine in women
This study looks at how a trait called alexithymia (difficulty identifying and describing feelings) relates to chronic migraine in women. It aims to help understand migraine better and possibly improve treatment.
Alessandria, ItalyAges 12–65 - NCT06888973Enrolling by invitationPhase 1/Phase 2
Stem cell infusion for autoimmune diseases
This clinical trial is testing if infusions of special stem cells (called mesenchymal stem cells) can help people with certain autoimmune diseases where standard treatments have not worked well enough. It is an early-phase study in Pakistan for adults (and some children for one condition) with rheumatoid arthritis, lupus, systemic sclerosis, ankylosing spondylitis, or dermatomyositis/polymyositis.
RawalpindiAges 18–50 - NCT06888661Enrolling by invitationEarly Phase 1
Testing EXG001-307 for spinal muscular atrophy in infants
This trial tests a new medicine called EXG001-307 for babies with spinal muscular atrophy (SMA) types 1 and 2. The goal is to see if it is safe and helps with muscle strength and breathing.
Shanghai, Shanghai MunicipalityAges 1 day–2 years - NCT06888570Enrolling by invitation
Liver health study for children & young adults with Down syndrome
This study looks at how eating patterns and body composition relate to fatty liver in children and young adults with Trisomy 21 (Down syndrome) or other genetic intellectual disabilities. It may help understand who is at risk and how to prevent liver problems.
Madrid, MadridAges 5–22 - NCT06888219Enrolling by invitation
Acupuncture for Swallowing and Tube Removal After Brain Injury
This study tests if acupuncture on the ear and body can help people with severe brain injuries regain the ability to swallow safely and have their breathing tube removed. It's for patients who are at least 1 month but no more than 3 months after a stroke or brain bleed.
FlorenceAges 18 years+ - NCT06887491Enrolling by invitation
Dual-tasking (thinking + moving) program for children with Duchenne MD
This study tests whether a special program that combines thinking tasks (like counting or remembering) with physical activities can help boys with Duchenne muscular dystrophy improve their thinking, movement, and ability to do everyday tasks independently.
Ankara, CankayaAges 6–12 - NCT06886386Enrolling by invitation
Nerve stimulation and physical therapy for spinal cord injury
This trial is testing whether a gentle electrical current (tsDCS) applied to the back of the head, along with physical therapy, can help improve movement and function in people with an incomplete spinal cord injury that happened more than a year ago.
Recife, PernambucoAges 18–55 - NCT06885294Enrolling by invitation
Physiotherapy with hypnosis for arm recovery after stroke
This study tests whether combining physiotherapy (special exercises) with hypnosis (a focused relaxation technique) can help improve arm and hand function after a stroke. It is for people who had a stroke at least 3 months ago and still have some difficulty using one arm or hand.
LiègeAges 18–80 - NCT06885138Enrolling by invitation
Testing brain stimulation for depression in Parkinson's disease
This trial tests if a gentle brain stimulation technique called tDCS can improve depression symptoms in people with Parkinson's disease. You'll receive either real or placebo stimulation over several sessions to see if it helps your mood.
MilanAges 35–75 - NCT06884956Enrolling by invitation
High-tech rehab effect on muscle MRI
This trial examines how high-tech rehabilitation for the lower leg affects muscle MRI results. It might help researchers understand if this type of therapy improves muscle condition.
Bosisio Parini, LCAges 8 years+ - NCT06882213Enrolling by invitation
Brain stimulation and core exercises for stroke recovery
This study tests if combining a gentle electrical brain stimulation (transcranial direct current stimulation) with core stability exercises helps improve trunk control after a stroke. It may be helpful if you are 55 or older, had your first stroke within the past six months, and can stand and walk on your own.
Banī SuwayfAges 55–75 - NCT06880484Enrolling by invitation
Far-infrared socks for diabetic nerve pain
This study tests whether special far-infrared socks can help relieve nerve pain and improve nerve function in people with diabetic nerve damage. If you have mild to moderate nerve pain and live in Kayseri, you may be able to join.
Talas, KayseriAges 19 years+ - NCT06880263Enrolling by invitation
VR training to help nurses manage delirium
This trial tests if virtual reality (VR) training can improve how nurses care for patients with delirium (sudden confusion). It is for nurses who work directly with patients in a hospital setting.
TaipeiAges 20–65 - NCT06880250Enrolling by invitation
Enzyme therapy study for Fabry disease patients
This trial tests if enzyme replacement therapy works well and is safe for Fabry disease. It is for people who are already prescribed this treatment.
AstrakhanAges 8–65 - NCT06879665Enrolling by invitation
Tandem trial for caregivers of TSC patients
This trial aims to improve access to interventions for Tuberous Sclerosis Complex (TSC)-related issues by working with adult caregivers. If you are an adult caring for someone with TSC, this study may help close the gap to better support and treatments.
Silver Spring, MarylandAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,516 recruiting neurology studies from the U.S. registry right now, out of 20,061 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.