Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,407 recruiting studies in this area right now.
By phase
- Not applicable9,742
- Phase 2782
- Phase 1577
- Phase 3534
- Phase 4342
- Phase 1/Phase 2307
- Phase 2/Phase 3123
Top conditions
- Stroke843
- Parkinson Disease429
- Alzheimer Disease342
- Multiple Sclerosis342
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea156
- Spinal Cord Injuries153
- Insomnia152
- Sarcopenia150
- Traumatic Brain Injury150
- Acute Ischemic Stroke138
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine114
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California680
- Massachusetts299
- New York292
- Florida274
- Texas267
- Maryland246
- Arizona213
- Alabama209
- Illinois189
- Pennsylvania177
Recruiting studies12,405 total
- NCT07660341RecruitingPhase 1
Study of CGB3002 in healthy volunteers
This trial tests a new drug, CGB3002, to see how safe it is and how the body processes it. Healthy volunteers are needed to help determine the right dose and check for side effects.
Melbourne, VictoriaAges 18–55 - NCT07498686Recruiting
Blood test for Parkinson's disease
This study is testing whether a simple blood test can help doctors better understand Parkinson's disease by looking at how a protein called alpha-synuclein behaves. It aims to find a new way to diagnose and track the disease.
Beijing, Beijing MunicipalityAges 18–95 - NCT06368726Enrolling by invitationPhase 1
Brain stimulation for kids with autism and genetic changes
This trial tests a gentle brain stimulation treatment called tDCS for children with autism or related conditions who also have certain genetic changes. It may help improve symptoms if your child meets the specific health and birth history requirements.
Albuquerque, New MexicoAges 6–11 - NCT07655869RecruitingEarly Phase 1
Lu177-DOTA-EB-RGD2 therapy for returning high-grade glioma
This trial tests a radioactive drug that targets a protein on tumor blood vessels to treat glioblastoma that has come back after standard treatment. It may help shrink tumors or slow their growth.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07224581RecruitingPhase 3
Study of a new drug for GRIN-related developmental disorder
This trial tests a new drug for children with GRIN-related neurodevelopmental disorder caused by certain gene changes. The drug aims to improve seizures and other symptoms.
Los Angeles, CaliforniaAges 1 month–18 years - NCT04107285Recruiting
Study brain changes in people with lymphoma after CAR T
This study looks at how thinking and brain function change over time in people with lymphoma who receive CAR T therapy. It may help doctors understand side effects and better support patients during and after treatment.
New York, New YorkAges 18 years+ - NCT05745298Recruiting
Electrical and breathing therapy to improve unassisted cough after spinal injury
This study tests whether pairing electrical stimulation with breathing muscle training can help you cough without needing assistance. It’s for people recovering from a spinal cord injury within the last year, and who can safely feel and respond to the electrical stimulation.
Miami, FloridaAges 18 years+ - NCT07523191Recruiting
Brain Activity Detection During Sleep Study
This research study tests a new method that uses magnetic pulses and brain-wave recordings to detect consciousness during sleep. Researchers want to validate this technology in healthy adults to see if it accurately measures brain activity.
Madison, WisconsinAges 18–85 - NCT06659120Recruiting
Fremanezumab to prevent period-related migraines
This study tests whether the migraine prevention drug fremanezumab can reduce the number of migraines you get around your period. It is for women who have regular cycles and migraines that are clearly linked to their menstrual period.
BernAges 18 years+ - NCT07438808Recruiting
How exercise affects brain flexibility in healthy adults
This study looks at how physical exercise might change the way the brain adapts and stays flexible in healthy younger and older adults. You may be able to join to help researchers understand how staying active keeps the brain sharp.
Loos, NordAges 20–80 - NCT06830421RecruitingPhase 3
High-dose chemo with stem cell transplant vs. standard therapy for older adults with CNS lymphoma
This study compares a high-dose chemotherapy followed by your own stem cell transplant to standard chemo-immunotherapy for older adults with newly diagnosed primary CNS lymphoma. The goal is to see which approach works better and is safer for people over 70.
Freiburg im Breisgau, Baden-WurttembergAges 65 years+ - NCT06478303Recruiting
Brain circuits for language and movement learning
This study uses brain imaging and stimulation to see how the brain connects language and movement. It may help improve how we learn motor skills and understand language.
Grenoble, GrenobAges 18–40 - NCT06478485Recruiting
A new way to plan neck surgery using MRI measurements
This trial is testing a new method to plan cervical spine surgery called laminoplasty. The goal is to use special measurements from MRI scans to better decide how to operate. This could lead to better recovery for people with spinal cord compression in the neck.
Nantong, JiangsuAges 18 years+ - NCT07042152Recruiting
Wearable device and coaching to improve arm use after stroke
This study tests whether a wearable device that tracks arm movement, plus coaching to use your weaker arm more, can help you recover better after a stroke. It's for people who are at least 6 months past their stroke and have some arm weakness but can still use their hand.
Irvine, CaliforniaAges 18–84 - NCT07495241Recruiting
How common is a carotid web in young people?
This study checks how often a small flap of tissue (called a carotid web) appears in the neck arteries of young people. It uses a simple ultrasound to look for this condition, which may help doctors understand stroke risk in younger adults.
Ostrava, Moravian-Silesian RegionAges 15–25 - NCT06461767Recruiting
rTMS for chronic migraine without recent prevention
This study tests whether repetitive transcranial magnetic stimulation (rTMS) — a noninvasive treatment using magnetic pulses on the head — can help prevent and treat chronic migraine pain. It may be an option for people who have never tried or are currently off migraine prevention medicines.
SohagAges Any age - NCT07493902Recruiting
Acupuncture for swallowing problems after a stroke
This study tests whether acupuncture can help people who have trouble swallowing after a stroke. It looks for volunteers who had a stroke within the past year and now have swallowing difficulty that is not too mild or too severe.
Tianjin, Tianjin MunicipalityAges 18–80 - NCT05331664RecruitingPhase 4
Dropless vitrectomy eye drops for retinal detachment surgery
This trial studies a “dropless” method (fewer post-surgery eye drops) after pars plana vitrectomy, a surgery used to repair a retinal detachment. It may help by improving comfort and simplifying recovery for people having this specific type of retinal detachment repair.
Boston, MassachusettsAges 40 years+ - NCT06598644Recruiting
Comparing two gentle neck pain treatments
This study tests two hands-on treatments for long-lasting neck pain: a gentle gliding movement called Sustained Natural Apophyseal Glide (SNAG) and a soft-tissue release technique called Instrument Assisted Soft Tissue Mobilization (IASTM). If you have had neck pain for more than 3 months, this trial may help find which method works better for you.
Rawalpindi, Punjab ProvinceAges 20–45 - NCT05416905Recruiting
Deep brain stimulation for facial dystonia using GPi or STN
This trial studies deep brain stimulation (a surgically placed device that sends targeted electrical signals) to treat idiopathic craniofacial dystonia when medicines or botulinum toxin haven’t helped enough. It compares stimulating two brain targets (GPi versus STN) to see which approach may improve symptoms.
BeijingAges 18–75 - NCT06484088RecruitingEarly Phase 1
Brain scanning study of frustration in healthy adults
This study looks at how the brain handles frustration in healthy adults using a special brain scanner called magnetoencephalography (MEG). It may help researchers understand normal brain responses to frustration.
Bethesda, MarylandAges 18–55 - NCT07486037Recruiting
Exercise program for African American Alzheimer's caregivers
This study is for African American caregivers of someone with Alzheimer's or a related dementia. It explores whether a gentle exercise program can help you feel better and manage the stress of caregiving.
Indianapolis, IndianaAges 18–99 - NCT07482930Recruiting
Nerve stimulation and breathing test study in healthy adults
This study tests if a gentle nerve stimulation device placed on the ear can change how you breathe during a lung function test. It is only for healthy volunteers aged 18–40 who have no heart, lung, nerve, or mental health conditions.
SinopAges 18–40 - NCT07481669RecruitingPhase 2
Stem cell transplant for lymphoma at high risk of brain relapse
This trial tests a stem cell transplant with a special chemo combination (TEAM) to see if it can prevent lymphoma from coming back in the brain or spinal cord for people with high-risk non-Hodgkin lymphoma.
Hangzhou, ZhejiangAges 18–70
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,407 recruiting neurology studies from the U.S. registry right now, out of 19,276 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.