Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,406 recruiting studies in this area right now.
By phase
- Not applicable9,740
- Phase 2783
- Phase 1576
- Phase 3534
- Phase 4342
- Phase 1/Phase 2307
- Phase 2/Phase 3124
Top conditions
- Stroke841
- Parkinson Disease427
- Alzheimer Disease342
- Multiple Sclerosis341
- Dementia227
- Ischemic Stroke201
- Epilepsy197
- Obstructive Sleep Apnea156
- Insomnia154
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke138
- Cerebral Palsy131
- Mild Cognitive Impairment130
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California681
- Massachusetts299
- New York292
- Florida275
- Texas265
- Maryland246
- Arizona212
- Alabama210
- Illinois188
- Pennsylvania177
Recruiting studies12,404 total
- NCT06128226Recruiting
Screening study for CLN2 disease in 6-year-olds
This study is screening children for a rare genetic condition called CLN2 disease. It looks for signs like seizures, speech loss, and movement problems to find out how common this condition is among 6-year-olds.
AdanaAges 2–6 - NCT05608408Recruiting
Preserving Memory in People With Epilepsy Using Brain Stimulation
This study tests a type of brain stimulation in people with epilepsy to see if it can help preserve memory. Researchers will compare memory and brain effects over time to understand whether stimulation changes memory outcomes.
Rochester, MinnesotaAges 18–65 - NCT05643092Recruiting
Testing scans and biomarkers for CAR T neurotoxicity risk
This study uses blood tests and brain imaging to better understand and predict nerve-system side effects that can happen after CAR T-cell treatment. It may help doctors spot people at higher risk sooner and guide safer care.
Shijiazhuang, HebeiAges 18–80 - NCT06918145Enrolling by invitation
LVA surgery for Alzheimer's disease
This study tests a surgery called lymphaticovenous anastomosis (LVA) as a possible treatment for Alzheimer's disease. The surgery connects tiny lymph vessels to veins to help clear waste from the brain.
Beijing, Beijing MunicipalityAges 50–85 - NCT07741851Recruiting
Monitoring muscle relaxants in the intensive care unit
This study tests a new way to check how well muscle relaxants are working in intensive care patients. It aims to make sure the monitoring is reliable, which could help doctors adjust treatment better for each patient.
Aix-en-ProvenceAges 18 years+ - NCT06910293Recruiting
Brain Activity During Menstrual Cycle vs. Fertility Treatment
This study looks at how natural menstrual cycles and ovarian stimulation (which mimics some fertility treatments) affect brain activity and hormone levels. Researchers want to understand normal brain changes during the cycle to help improve fertility treatments.
Abu Dhabi, Abu Dhabi EmirateAges 25–35 - NCT06890520Recruiting
Brain chemistry study for mitochondrial disease
This study looks at brain chemicals in people with primary mitochondrial disease using an MRI scan. It aims to understand how the disease affects the brain and may help guide future treatments.
Philadelphia, PennsylvaniaAges 8–75 - NCT07183670Enrolling by invitation
Testing a Voice Valve to Remove Breathing Tubes in Prolonged Consciousness Disorders
This study tests a new way to help people with long-lasting disorders of consciousness get their tracheostomy tube removed using a voice valve. If you qualify, this might help improve recovery and communication.
Beijing, Beijing MunicipalityAges 18–80 - NCT06909071Recruiting
Smart insulin pump for blood sugar control after brain surgery
This trial tests a smart insulin pump (hybrid closed-loop system) to control high blood sugar after brain surgery for bleeding strokes. It's for people with type 2 diabetes who are stable enough to leave the intensive care unit and are getting tube feedings.
Taiyuan, ShanxiAges 18–75 - NCT07420153Recruiting
Arm cuff treatment before surgery to prevent confusion
This study tests whether using a blood pressure cuff on the arm before surgery (called remote ischemic preconditioning) can help prevent confusion (delirium) after surgery. It is for older adults having planned non-cardiac surgery who are at risk for delirium.
Hamburg, Free and Hanseatic City of HamburgAges 50 years+ - NCT05852730RecruitingPhase 2
Nasal scopolamine and sensory training to reduce motion sickness
This Phase 2 study tests whether a nasal scopolamine medicine plus sensory training can reduce motion sickness and improve movement control during demanding motion experiences (like astronaut training or flight simulations). It may help people who get sick in these settings, as long as they have no related medical problems and can safely take scopolamine.
Houston, TexasAges 18–65 - NCT06903416RecruitingPhase 2/Phase 3
Nerve stimulation for arm and hand function after spinal cord injury
This study tests a non-invasive, painless nerve stimulation technique to see if it can improve arm and hand function after a spinal cord injury. It may help people who have had a neck-level injury more than 9 months ago.
Edmonton, AlbertaAges 18–75 - NCT07291310Enrolling by invitation
Virtual reality therapy for children with brachial plexus injury
This trial tests if playing virtual reality games while doing dual tasks can help the brain rewire and improve arm function in children with a brachial plexus injury. It could offer a fun and engaging new approach to rehabilitation.
Istanbul, CevizlibağAges 7–14 - NCT06902233Recruiting
Brain stimulation for chronic low back pain
This trial tests if a non-invasive brain stimulation technique can help people with long-lasting low back pain. It uses mild electrical currents to adjust brain activity and may reduce pain and improve daily function.
Dunedin, OtagoAges 18–75 - NCT06900101Recruiting
Monitoring study in brain injury intensive care
This study uses a special monitoring system to closely watch patients in the neurologic intensive care unit. It may help doctors better understand and treat brain injuries.
France, BronAges 18–90 - NCT05662280Recruiting
Brain stimulation study for teens with ADHD and memory trouble
This study tests whether changing brain activity can improve working memory in teens who have ADHD and trouble remembering and holding information in mind. You and your parent will answer questionnaires, and brain imaging/brain-stimulation testing (MRI/TMS) may be used, with compensation for each session.
East Providence, Rhode IslandAges 12–18 - NCT07465302RecruitingPhase 2
Early high oxygen therapy for spinal cord injury
This study tests giving high levels of oxygen soon after a spinal cord injury to see if it can help recovery. It is for people who are awake but need a breathing tube and have certain types of spinal cord injury in the neck or upper back.
Gainesville, FloridaAges 18–85 - NCT06900452Recruiting
Pistachio breakfast and brain function in older adults
This study tests whether eating a pistachio-rich breakfast can improve memory and thinking in healthy older adults. If you qualify, you'll eat special breakfast meals and do some computer-based thinking tasks to measure how your brain performs.
Reading, BerkshireAges 65–80 - NCT06898151Recruiting
Comparing timing of carotid surgery or stenting after stroke
This trial compares the best timing for surgery or stenting to open a narrowed carotid artery after a minor stroke. The goal is to see if doing the procedure sooner or later reduces the chance of another stroke.
BeijingAges 18 years+ - NCT06898073Recruiting
Walking and thinking training after stroke
This trial tests whether combining walking on a curved path with doing simple thinking tasks can improve recovery after a stroke. It is for people who can walk at least 10 meters and have some arm and leg movement.
Kaohsiung CityAges 40–80 - NCT07158710RecruitingPhase 1
Study of HSK42360 for brain tumors with BRAF V600 mutation in children
This trial tests a new drug, HSK42360, for children with recurrent brain tumors that have a specific gene change called BRAF V600. The goal is to see if the drug can help when standard treatments have stopped working.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06867185Recruiting
Electrical stimulation for nerve healing after finger nerve repair
This trial tests whether giving a small electrical signal during surgery helps nerves in the finger heal better after they are repaired. It might help you regain feeling and movement faster.
Indianapolis, IndianaAges 18–80 - NCT06864715Recruiting
Preventing depression after a stroke with behavioral activation
This study tests if a talking therapy called behavioral activation can prevent depression in older adults who have had a stroke and have low income. It is for people who are not already severely depressed and live at home.
Houston, TexasAges 55 years+ - NCT06687460Enrolling by invitation
Nerve stimulation after arm nerve injury
This trial tests a mild electrical stimulation to the nerves in your arm to help repair a recently damaged median or ulnar nerve (nerves that control hand movement). It might help your hand function recover better after surgery or injury.
Tainan, TaiwanAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,406 recruiting neurology studies from the U.S. registry right now, out of 19,323 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.