Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,406 recruiting studies in this area right now.
By phase
- Not applicable9,740
- Phase 2783
- Phase 1576
- Phase 3534
- Phase 4342
- Phase 1/Phase 2307
- Phase 2/Phase 3124
Top conditions
- Stroke841
- Parkinson Disease427
- Alzheimer Disease342
- Multiple Sclerosis341
- Dementia227
- Ischemic Stroke201
- Epilepsy197
- Obstructive Sleep Apnea156
- Insomnia154
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke138
- Cerebral Palsy131
- Mild Cognitive Impairment130
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California681
- Massachusetts299
- New York292
- Florida275
- Texas265
- Maryland246
- Arizona212
- Alabama210
- Illinois188
- Pennsylvania177
Recruiting studies12,404 total
- NCT06288256Recruiting
Spine surgery study: genes, thinking, and pain
This study is for people getting planned spine surgery. It looks at how your genes and thinking skills might affect your pain and use of pain medicine after surgery.
New York, New YorkAges 18 years+ - NCT06108336Recruiting
How the cerebellum affects thinking and sequencing
This study uses MRI and TMS to understand how the cerebellum, a brain region, helps with cognitive sequencing—putting thoughts or actions in order. It may lead to better treatments for cognitive problems.
Baltimore, MarylandAges 18–50 - NCT06163261Recruiting
Personalized exercise for pituitary tumor recovery
This study tests whether a personalized physical activity plan can improve well-being for people who have had surgery for a non-functioning pituitary adenoma. It aims to see if exercise helps with recovery and quality of life.
Gothenburg, Västra Götaland CountyAges 18–75 - NCT06895473RecruitingPhase 2
Spinal injection to prevent nerve side effects from CAR-T therapy
This trial tests if a spinal injection of three common chemotherapy drugs can reduce or prevent serious brain and nerve side effects in people receiving CAR-T cell therapy for cancer.
Portland, OregonAges 18 years+ - NCT05521984RecruitingPhase 1
Dapagliflozin trial for children with hard-to-treat brain tumors
This Phase 1 trial tests whether dapagliflozin (an SGLT2 medicine) can help shrink or control certain pediatric brain tumors or other solid tumors that have come back or won’t respond. It’s designed mainly to check safety and early signs of effect in children and young adults who have limited treatment options.
St Louis, MissouriAges 6–21 - NCT05598723RecruitingPhase 3
Botox versus Xeomin for chronic migraine in adults
This Phase 3 study compares two headache injections—Botox and Xeomin—for people with chronic migraine. It may help find out which option works better to reduce frequent, long-lasting migraine days.
Jacksonville, North CarolinaAges 18–89 - NCT06078176Recruiting
Spinal cord injury trial for easier bowel emptying
This trial tests if stimulating certain nerves can help people with spinal cord injury empty their bowels faster and with less effort. It may help reduce the time needed for bowel routines and make them easier.
Syracuse, New YorkAges 18 years+ - NCT04633655Recruiting
Study tests nerve side effects from certain chemotherapy drugs
This study looks at how chemotherapy that can affect nerves (“neurotoxic” chemo) changes nerve function over time. It may help researchers better measure nerve side effects and improve care for people who need these cancer treatments.
Birmingham, AlabamaAges 18 years+ - NCT07173634Enrolling by invitation
Speaking valve trial for tracheostomy removal in consciousness disorders
This trial tests whether using a speaking valve (a small one-way valve that lets you breathe and speak) helps people with a tracheostomy and long-term consciousness problems safely remove their tracheostomy tube, compared to a standard capping method.
Beijing, Beijing MunicipalityAges 18–80 - NCT07123402Enrolling by invitationPhase 2
TRD205 for chronic pain after surgery
This trial tests a new tablet called TRD205 for people who have had long-lasting nerve pain after surgery (at least 3 months). The goal is to see if it can reduce pain safely.
BeijingAges 18–80 - NCT07142174Recruiting
New implant for neck pain and nerve compression
This trial tests a new type of implant that is placed in the back of your neck to help open up space for nerves and improve spine alignment. It may help people with pain, numbness, or weakness from a pinched nerve or spinal cord compression caused by wear-and-tear changes.
RiyadhAges 18 years+ - NCT07118020Enrolling by invitation
Study of Tutopatch in skull surgery after craniotomy
This study is testing a patch called Tutopatch used during craniotomy, a surgery that opens part of the skull. The goal is to gather more information about how well it works after it is already approved for use.
SalzburgAges Any age - NCT04362709Recruiting
Post-surgery care study for people having brain surgery
This trial studies how to manage care after anesthesia for people having neurosurgery at Beijing Tiantan Hospital. It may help improve comfort and recovery planning after brain surgery.
BeijingAges Any age - NCT06649500Recruiting
Comparing two balance therapy methods for older adults
This trial tests whether a high-tech treadmill (Walker View) or group therapy works better for improving balance and preventing falls in older adults. It also uses artificial intelligence to predict fall risk early.
Rome, RomeAges 65 years+ - NCT07048951Recruiting
Memory and awareness after ICU: understanding moments of disconnect
This trial studies episodes of lost or altered consciousness that some people experience after a long stay in the ICU. It aims to understand how these episodes affect memory and recovery.
Liège, LiègeAges 18 years+ - NCT07140874RecruitingPhase 2
Zinc as an add-on treatment for neck dystonia
This trial tests if taking zinc supplements can improve symptoms of cervical dystonia (a condition causing neck muscle spasms) for people who already get Botox injections. It adds zinc to your regular Botox treatment to see if it helps control symptoms better.
Gainesville, FloridaAges 18–89 - NCT07113353Recruiting
Non-Invasive Brain Pressure Monitoring Study
This study is testing a new way to measure pressure inside the skull without needing a separate procedure. It may be an option for people having brain surgery, getting spinal taps, or needing their VP shunt adjusted.
Coppell, TexasAges 18 years+ - NCT06094569Recruiting
Screening for stroke in the back of the brain
This study uses MRI scans to find strokes caused by blockages in the arteries at the back of the brain. It may help doctors learn more about these strokes and how to better care for people who have them.
Tianjin, Tianjin MunicipalityAges Any age - NCT07711041Recruiting
Comparing three treatments for chronic neck pain
This trial compares three therapies—integrated neuromuscular inhibition, dry cupping, and dry needling—to see which works best for long-lasting mechanical neck pain. It may help if you have had neck pain for over six months with trigger points in your upper shoulder muscle.
GizaAges 18–40 - NCT07713550Recruiting
Genetic profiling to guide treatment for advanced solid tumors
This study tests whether analyzing the DNA of your tumor (from a tissue sample or blood draw) can help find the best treatment for your advanced cancer. Researchers will look for genetic changes that could make you eligible for targeted therapy or a clinical trial.
AnderlechtAges 18 years+ - NCT07697560RecruitingPhase 1
Safety of AH-008 in healthy volunteers
This trial tests a new medicine called AH-008 in healthy people to see if it's safe and how the body processes it. It is a first-in-human study with a single dose.
Salt Lake City, UtahAges 18–65 - NCT07671950Recruiting
Deep brain stimulation for neuropathic dental pain
This trial studies whether deep brain stimulation (DBS) can help people with a type of nerve-related tooth pain called atypical odontalgia. It is for those who have not found relief from standard treatments like medications or injections.
Vancouver, British ColumbiaAges 19–80 - NCT07623785Recruiting
Beef and Brain Health in Older Adults
This study looks at whether eating lean beef and dairy products daily affects brain health markers in people 65 and older. Researchers will track blood, urine, and other samples to see if beef consumption influences how your brain functions at the molecular level.
Brookings, South DakotaAges 65 years+ - NCT07617441Recruiting
Brain and Psychology Study of Hard-to-Treat Migraines
This research study compares brain structure and psychological traits in people with chronic migraines that don't respond well to standard treatments versus healthy volunteers without migraines. Understanding these differences may help doctors develop better treatment options for difficult-to-treat migraines.
Catanzaro, CatanzaroAges 18–75
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,406 recruiting neurology studies from the U.S. registry right now, out of 19,323 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.