Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,941 recruiting studies in this area right now.
By phase
- Not applicable9,343
- Phase 2764
- Phase 1557
- Phase 3513
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke796
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis329
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management114
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California659
- Massachusetts305
- New York294
- Florida271
- Texas266
- Maryland248
- Alabama207
- Arizona207
- Illinois181
- Pennsylvania176
Recruiting studies11,941 total
- NCT06681610Recruiting
Testing pulse stimulation to improve movement in ALS
This trial studies if a non-invasive pulse stimulation can help people with ALS move better. It aims to see if this treatment can improve motor function.
Barcelona, CataloniaAges 21–80 - NCT06677866Recruiting
Group therapy for teens with Fragile X or autism
This trial tests if group cognitive behavioral therapy (CBT) can help teens with Fragile X syndrome or autism spectrum disorder improve social and emotional skills. It looks at how teens with these conditions respond to a structured group program.
RomeAges 13–19 - NCT05416684Recruiting
PEEK vs titanium skull repair after brain surgery
This is an observation study that compares outcomes after two types of skull repair: PEEK and titanium. It may help doctors understand which option works best and how patients recover, without requiring an experimental treatment plan.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06680011Recruiting
Study of diagnostic markers for neurosyphilis
This study looks for better ways to diagnose neurosyphilis, an infection that affects the brain and spinal cord. Researchers will compare test results from people with neurosyphilis, people with syphilis but no brain involvement, and healthy volunteers.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06572748Recruiting
Cooking study for older adults with memory concerns
This study tests a cooking program called Chef Anchor 3.0 for older adults with mild memory problems or dementia. It looks at whether learning to cook can help with thinking skills and daily life.
Hong KongAges 60 years+ - NCT07651514Recruiting
Magnesium and Melatonin for Better Sleep and Leg Cramps
This study tests whether taking daily magnesium and melatonin supplements can help improve sleep quality and reduce nighttime leg cramps in adults. You'll wear a special ring to track your sleep and use a smartphone app to log your experiences.
Palm Beach Gardens, FloridaAges 40–75 - NCT07651306Recruiting
Bone Loss After Stroke: New X-ray Detection Method
This study tests whether a new way of measuring X-rays can detect bone loss in the shoulder after a stroke. The research may help doctors identify patients at risk for fractures earlier.
IstanbulAges 18 years+ - NCT07646613RecruitingPhase 2
Testing an inhaled migraine medicine for quick relief
This study tests a new inhaled powder form of a migraine medication called dihydroergotamine (DHE) to see if it safely and effectively stops migraine attacks. If you have frequent migraines, this trial might offer you a new treatment option to try.
Phoenix, ArizonaAges 18–65 - NCT07646678RecruitingPhase 2/Phase 3
TAK-360 Extension Study for Narcolepsy or Excessive Sleepiness
This is a follow-up study for people who already completed a TAK-360 trial for narcolepsy (a sleep disorder causing sudden sleep attacks) or idiopathic hypersomnia (excessive daytime sleepiness). Researchers want to see if continuing TAK-360 remains safe and effective for you.
Chula Vista, CaliforniaAges 18–71 - NCT07654855Recruiting
Long-term safety of eplontersen in ATTR patients
This study follows people who already took part in an earlier trial (D8450R00003) to see how safe eplontersen is over the long term. It also includes people who had a liver transplant or severe liver problems.
Los Angeles, CaliforniaAges 18 years+ - NCT07652034Recruiting
Tracking migraine relief after a minimally invasive artery procedure
This study follows adults who undergo a procedure called middle meningeal artery embolization—a minimally invasive treatment that blocks blood flow to a specific artery thought to trigger migraines. The trial simply tracks your symptoms and quality of life before and after the procedure to understand how well it works.
Tacoma, WashingtonAges 18–64 - NCT07646782Recruiting
Human Observatory Study: Aging and Longevity Research
This study observes how people age over time to better understand what helps people live longer and healthier lives. You'll share health information through surveys or online screening, and researchers will track changes in your health and wellbeing.
Boulder, ColoradoAges 18 years+ - NCT07651826Recruiting
Study of Immiseal Dural Sealant in Brain and Spine Surgery
This study tracks how well Immiseal, a special sealing material, works when applied during brain or spine surgery to prevent fluid leaks from the protective membrane around the brain and spinal cord. You'll be followed after surgery to see how well the sealant performs and if you have any side effects.
RigaAges 18–75 - NCT07648693Recruiting
Brain Protection Device During Aortic Valve Replacement
This trial tests a new device called CHORDS that protects your brain during transcatheter aortic valve replacement (TAVR), a minimally invasive procedure to fix a narrow aortic valve. The device works by blocking debris that might travel to your brain during the procedure.
Bengbu, AnhuiAges 18 years+ - NCT07647510RecruitingPhase 3
Testing Claseprubart for Generalized Myasthenia Gravis
This study tests whether a new drug called claseprubart can help adults with generalized myasthenia gravis (a condition where muscles get weak and tired easily). The drug works by targeting part of the immune system that damages muscles.
Pasadena, CaliforniaAges 18–80 - NCT07647315Recruiting
Wireless Brain Implant for Speech Recovery
This trial tests a small wireless device implanted in the brain to help people with severe speech difficulties—caused by stroke, ALS, or brain injury—communicate again. The device reads brain signals and converts them to Mandarin Chinese speech.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07654114RecruitingPhase 2
Testing CTH120 for men with Fragile X syndrome
This trial tests a new medicine called CTH120 to see if it is safe and helpful for adult men with Fragile X syndrome. You may be able to join if you meet certain health and age requirements.
Barcelona, BarcelonaAges 18–45 - NCT06055569Recruiting
Rehabilitation for arm recovery after stroke using observation and muscle stimulation
This trial tests if observing arm movements paired with muscle stimulation helps stroke survivors regain arm function. It may be an option if your stroke affected one arm and you are between two weeks and six months post-stroke.
Milan, ItaliaAges 18 years+ - NCT02756091Recruiting
Study of treatment after a new brain artery dissection
This study looks at people who have had a fresh tear in a brain artery within the last month. The goal is to learn the best way to manage this condition and improve outcomes.
Osaka, KansaiAges 18 years+ - NCT06684249Recruiting
Comparing nerve block and Botox for chronic migraine
This study compares two treatments for chronic migraine: a nerve block (injection near the nerves in the head) and Botox injections. It aims to see which one works better to reduce headache days and improve quality of life.
Zagazig, Sharqia ProvinceAges 18–65 - NCT06686524RecruitingPhase 1
CD19-targeted UCAR-T for refractory juvenile dermatomyositis
This trial tests a new type of immune cell therapy (UCAR-T) that targets a protein called CD19 to treat children with a severe form of juvenile dermatomyositis that hasn't responded to standard treatments. It aims to calm the overactive immune system and reduce symptoms like muscle weakness and skin rashes.
Hangzhou, ZhejiangAges 5 years+ - NCT07654504Recruiting
Turkish questionnaire study for brachial plexus birth palsy
This study tests a Turkish version of a questionnaire about how brachial plexus birth palsy (a nerve injury at birth affecting arm movement) impacts daily life. It may help people understand and communicate their symptoms better.
Istanbul, IstanbulAges 18 years+ - NCT07651631Recruiting
Brain Bleeding Surgery Registry and Treatment Study
This study tracks patients who have had sudden, severe bleeding in the brain and received minimally invasive surgery (a less-invasive surgical approach) to treat it. Researchers want to understand outcomes and improve treatment for this serious condition.
Atlanta, GeorgiaAges 18 years+ - NCT07651540Recruiting
Understanding Sensory Nerve Damage: The Neuronoscore Study
This study helps doctors better understand and measure sensory nerve damage (nerves that feel pain, temperature, and touch). You may qualify if you have a specific type of nerve damage caused by cancer, autoimmune disease, platinum chemotherapy, or a rare genetic condition.
AngersAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,941 recruiting neurology studies from the U.S. registry right now, out of 18,432 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.