Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,415 recruiting studies in this area right now.
By phase
- Not applicable9,746
- Phase 2784
- Phase 1576
- Phase 3535
- Phase 4343
- Phase 1/Phase 2307
- Phase 2/Phase 3124
Top conditions
- Stroke841
- Parkinson Disease425
- Alzheimer Disease342
- Multiple Sclerosis341
- Dementia227
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea156
- Insomnia154
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke139
- Cerebral Palsy132
- Mild Cognitive Impairment130
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California680
- Massachusetts300
- New York292
- Florida275
- Texas266
- Maryland246
- Arizona213
- Alabama210
- Illinois188
- Pennsylvania178
Recruiting studies12,413 total
- NCT06571149RecruitingPhase 4
Blood thinners and clot-busting drugs for stroke
This trial tests whether giving a clot-dissolving medicine (alteplase or tenecteplase) is safe and effective for people who have had a stroke and are taking a blood thinner (DOAC) like apixaban or rivaroxaban. It aims to see if this treatment can still be given within a few hours of the stroke.
EisenstadtAges 18 years+ - NCT07465783Recruiting
Music therapy for sleep and calm in dementia care
This study tests whether a music therapist working one-on-one with people who have dementia can help them fall asleep better and stay calmer during the day. It takes place in a locked dementia care unit.
Saint-EtienneAges 60 years+ - NCT06067893Enrolling by invitationPhase 4
Low dose sedation medicine for pain after scoliosis surgery
This trial tests a low dose of a sedative medicine, dexmedetomidine, given during and after spine surgery to see if it helps with pain. It is for teens and adults with scoliosis having back fusion surgery.
Kansas City, MissouriAges 10–21 - NCT07738003Recruiting
Perinatal Autism Genetics and Epigenetics Study
This study looks at genetics and other factors that may be linked to autism. Pregnant women in their first or second trimester are invited to join, and their babies will be followed to see how they develop.
Iowa City, IowaAges birth–50 years - NCT06239272RecruitingPhase 1/Phase 2
Personalized treatment for NRSTS in children and young adults
This trial tests a personalized treatment plan for children and young adults with a type of soft tissue sarcoma (NRSTS). It uses a combination of surgery, targeted radiation, and two drugs (pazopanib and selinexor) to fight cancer while reducing side effects. The study is looking for people who have not been treated before for this sarcoma.
Atlanta, GeorgiaAges Up to 30 years - NCT07562178Recruiting
Pemafibrate to prevent stroke from brain artery narrowing
This trial tests whether a medication called pemafibrate can help prevent future strokes in people who have had a recent stroke or TIA (mini-stroke) caused by a narrowed artery inside the brain. The medication works by lowering triglycerides (a type of fat in the blood).
Toyoake, Aichi-kenAges 18 years+ - NCT07319091Recruiting
Cystinosis and Mitochondrial Energy Study
This study looks at how cystinosis affects the energy centers (mitochondria) in your cells. It may help doctors understand how cysteamine treatment works in patients with kidney cystinosis.
BronAges 2 years+ - NCT07072195RecruitingPhase 2
A study of AMC6156 for people with muscle loss
This trial tests an investigational drug called AMC6156 to see if it can help improve muscle mass and strength in older adults with sarcopenia (age-related muscle loss). Participants will also follow exercise and nutrition guidance.
Seongnam-si, Gyeonggi-doAges 65 years+ - NCT06916403Enrolling by invitation
Ketamine infusions for fibromyalgia pain
This study looks at whether ketamine given through an IV can help reduce fibromyalgia pain. It reviews past treatments and also plans new treatments to see how well they work and how safe they are.
Thornhill, OntarioAges 18 years+ - NCT05296889Recruiting
Safety follow-up for Ennovate cervical device
This study checks how safely and effectively a cervical device (Ennovate® Cervical) works after it’s been used in routine care. It may help by monitoring real-world safety and performance over time.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT05697861Enrolling by invitation
Follow-up study for people previously treated with NTLA-2001
This study checks how people are doing long-term after receiving NTLA-2001 in an Intellia clinical trial. If you previously took part and agree to be followed, this may help the researchers understand lasting safety and effects.
ParisAges 18 years+ - NCT07501702RecruitingPhase 2
Study of Povetacicept for Generalized Myasthenia Gravis
This trial tests a new medicine called povetacicept for people with generalized myasthenia gravis. The goal is to see if it can help improve muscle weakness and symptoms.
Mission Hills, CaliforniaAges 18–80 - NCT07743255Enrolling by invitation
Preventing migraines in children with melatonin and propranolol
This study tests whether two common medicines, melatonin and propranolol, can help prevent migraines in children. If your child has frequent, disabling migraines, this treatment might reduce how often they occur and improve daily life.
Multan, Punjab ProvinceAges 5–15 - NCT06994442RecruitingPhase 3
Best pain relief for children on a breathing tube
This study tests adding extra pain medicines (acetaminophen or an NSAID) to usual opioid pain treatment for children on a breathing machine. The goal is to find the safest and most effective way to manage pain.
Little Rock, ArkansasAges 2 months–17 years - NCT07740694Recruiting
ECT study for older adults with depression
This study looks at how ECT affects brain activity and inflammation in older adults with depression. It may help researchers understand why ECT works and improve treatment.
Istanbul, BakırköyAges 55 years+ - NCT07476781Recruiting
Liquid biopsy study for solid tumours and brain tumours
This study collects samples of spinal fluid and blood from people with solid tumours that have spread to the brain or spine, or who have primary brain tumours. The goal is see if these samples can help doctors detect and monitor these cancers more easily.
Toronto, OntarioAges 18 years+ - NCT07739875Recruiting
App-based therapy for post-stroke word-finding
This trial tests a therapy delivered through a smartphone app to help people with aphasia (trouble finding words after a stroke) improve their ability to name things. The therapy happens in daily life, not in a clinic, and is personalized to the words you need most.
Boston, MassachusettsAges 18–89 - NCT07738978Recruiting
Movement and health study for paralysis
This study is looking at ways to improve movement and health for people with paralysis from conditions like spinal cord injury, stroke, traumatic brain injury, or multiple sclerosis. It involves exercises and may include electrical stimulation to help your leg and trunk muscles work better.
Cleveland, OhioAges 18 years+ - NCT06735014Recruiting
ALS imaging study to track disease progression
This study uses MRI brain scans to understand how ALS affects the brain over time. It may help researchers develop better ways to measure the disease.
Gainesville, FloridaAges 18 years+ - NCT07740239Recruiting
Study on frailty in seriously ill adults
This study looks at why some seriously ill adults become frail. It involves imaging and other tests to help doctors better understand and care for patients with serious conditions.
TampereAges Any age - NCT07739992Recruiting
Acute intermittent hypoxia for spinal cord injury
This study tests a breathing therapy called acute intermittent hypoxia, which involves short bursts of low oxygen, to see if it can improve leg movement in people with spinal cord injury. It may help strengthen the muscles that lift the foot.
Chicago, IllinoisAges 18–75 - NCT05157477Recruiting
Addressing sensory issues in adults with autism
This study tests a virtual reality program to help adults with autism cope with sensory problems and improve social skills. Participants will practice handling sensory situations in a safe VR environment.
TaipeiAges 20–45 - NCT07738120Recruiting
Virtual reality and exercise for multiple sclerosis
This study tests whether using virtual reality along with exercise can help people with multiple sclerosis. It aims to improve physical function and well-being.
PontevedraAges 18 years+ - NCT06847321RecruitingPhase 2
Testing LHP588 for Alzheimer's linked to a mouth bacteria
This trial tests a new medication, LHP588, for people with Alzheimer's who also have a common mouth bacteria called P. gingivalis. The goal is to see if targeting this bacteria can help slow down memory loss.
Phoenix, ArizonaAges 55–80
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,415 recruiting neurology studies from the U.S. registry right now, out of 19,354 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.