Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,941 recruiting studies in this area right now.
By phase
- Not applicable9,343
- Phase 2764
- Phase 1557
- Phase 3513
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke796
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis329
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management114
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California659
- Massachusetts305
- New York294
- Florida271
- Texas266
- Maryland248
- Alabama207
- Arizona207
- Illinois181
- Pennsylvania176
Recruiting studies11,941 total
- NCT07631182Recruiting
Action Observation Therapy for Stroke Recovery via Telehealth
This trial tests a therapy where you watch videos of hand and arm movements and then practice them yourself, delivered through video calls from home. It's designed to help people recover arm and hand function after a stroke.
Karabük, MerkezAges 18 years+ - NCT07634523RecruitingPhase 4
Amino acids to prevent muscle loss after knee surgery
This study tests whether a supplement containing branched chain amino acids (special protein building blocks) can help prevent muscle loss in older adults having knee replacement surgery. The goal is to help patients recover strength and mobility more quickly after their operation.
Seongnam-si, Gyeonggi-doAges 40–100 - NCT07637357Recruiting
How anesthesia affects thinking after weight-loss surgery
This study looks at how different types of anesthesia used during sleeve gastrectomy (a weight-loss surgery) may affect your memory and thinking skills after the operation. Researchers want to understand which anesthesia approach is safest for your brain.
Istanbul, SancaktepeAges 18–65 - NCT07636720Recruiting
Sleep monitoring with Parkinson's deep brain stimulation device
This study uses a special sensing device in your existing Parkinson's deep brain stimulation implant to monitor your sleep patterns. Researchers want to understand how sleep and the stimulation device interact, which could help improve treatment for Parkinson's patients.
San Antonio, TexasAges 40–80 - NCT07630532Recruiting
Virtual Reality Relaxation for Better Sleep
This study tests whether using virtual reality relaxation programs can help people who have trouble sleeping. Researchers want to see if this technology can help you fall asleep faster and sleep better through the night.
Québec, QuebecAges 25–50 - NCT07635329Recruiting
Home Vision Therapy Guided by Brain Scans
This study tests whether vision rehabilitation exercises done at home, guided by brain imaging, can help people regain vision after a stroke, brain injury, or tumor. Participants will use brain scans to personalize their therapy.
Washington D.C., District of ColumbiaAges 18 years+ - NCT07634627Recruiting
Understanding why teens get scoliosis – a protein study
This study looks at how proteins in the blood may help us understand why teenagers develop scoliosis (a sideways curve in the spine). If you have mild to moderate scoliosis and are getting care at Children's Hospital Colorado, you may be able to join this study to help researchers learn more about the condition.
Aurora, ColoradoAges 10–17 - NCT07635498Recruiting
Virtual versus in-person care after stroke
This study compares two ways of caring for stroke patients who aren't candidates for emergency clot-removal surgery. Half will receive care through a virtual stroke unit (telemedicine), and half will receive traditional in-person care at the hospital. The goal is to see if both approaches work equally well for recovery and safety.
SevilleAges 18 years+ - NCT07636876Enrolling by invitation
Italian MS and Related Disorders Patient Registry
This is a registry study that collects health information from people with multiple sclerosis and related conditions. By joining, you help researchers better understand these diseases and improve future treatments.
Genova, GenovaAges Any age - NCT07630207Recruiting
Blood vessel health in adults with Down syndrome
This study looks at how blood vessels work in adults with Down syndrome compared to those without Down syndrome. It aims to understand heart health better and may help improve future care.
Las Vegas, NevadaAges 18–35 - NCT07629687Recruiting
Ear Nerve Stimulation for Balance After Stroke
This trial tests a non-invasive device that stimulates a nerve in your ear to help improve balance and body control after stroke. It may help you regain stability and reduce symptoms like muscle tightness.
Islamabad, Punjab ProvinceAges 18–70 - NCT07637773Recruiting
Brain Stimulation for Depression and Loss of Interest in Older Adults
This trial tests a new brain stimulation technique called tACS (transcranial alternating current stimulation) to treat depression in people aged 60 and older, especially the symptom of losing interest in things you once enjoyed. Researchers believe this targeted stimulation may help improve mood and motivation.
Tianjin, Tianjin MunicipalityAges 60 years+ - NCT07629635RecruitingPhase 3
Closing a heart hole to treat migraines
This trial tests whether closing a small hole in the heart (called a PFO) can help eliminate migraines. If you have frequent migraines and no other major health issues, this procedure might reduce or stop your headaches.
New York, New YorkAges 18–55 - NCT07629674Recruiting
Video Therapy to Help Leg Movement Recovery After Stroke
This study tests whether watching specially designed videos can help improve leg strength and walking ability in people recovering from stroke. You'll receive this video therapy alongside your regular rehabilitation care.
Saint-EtienneAges 18–80 - NCT07633821Recruiting
3D-Printed Hand Brace for Daily Living Support
This trial tests a custom 3D-printed hand brace (orthosis) designed to help you use your hand better in everyday activities. You would wear it regularly to see if it improves your ability to do daily tasks like eating, dressing, or writing.
Amsterdam, North HollandAges 18 years+ - NCT07637825Recruiting
Ultrasound brain stimulation for improving arm and leg movement after stroke
This study tests a painless, non-invasive ultrasound treatment that stimulates the brain to help improve arm and leg movement after a stroke. It aims to see if this treatment can help people recover more function.
Taizhou, JiangsuAges 18–75 - NCT07630311Recruiting
Balance and walking study in multiple sclerosis
This study looks at how multiple sclerosis affects balance, walking patterns, and movement. Researchers will use motion analysis to understand changes, which could help improve treatments.
IoanninaAges 18 years+ - NCT07631169Recruiting
Action Observation Therapy for Stroke Hand Recovery
This study tests whether watching and practicing hand movements (with one or both hands) can help improve hand function and grip strength in people who had a stroke on the left side of their brain. The therapy uses observation and practice to retrain the brain and hand after stroke.
Karabük, MerkezAges 18 years+ - NCT07632612Recruiting
Nerve-Stretching Techniques for Sciatica Pain Relief
This trial compares two hands-on physical therapy techniques—one that stretches the sciatic nerve and one that moves it gently—to see which works better for sciatica pain that has lasted several months. You'll receive one of these treatments to help reduce leg pain and improve your ability to walk and move.
Rawalpindi, Punjab ProvinceAges 20–50 - NCT07631260Enrolling by invitation
ICU Diary Help for Caregiver Sleep and Stress
This study tests whether keeping a diary about your loved one's ICU stay helps you sleep better, feel less tired, and manage stress. You would be a family member or caregiver of someone on a breathing machine in the intensive care unit.
Taichung, Not in USAAges 20 years+ - NCT06689865Recruiting
Hearing aid study for adults with mild to moderate hearing loss
This study tests four different ways to provide over-the-counter hearing aids to adults with mild-to-moderate hearing loss. It aims to find the best approach to help people hear better and improve their quality of life.
Aurora, ColoradoAges 40 years+ - NCT06695455Recruiting
Can music help people with Parkinson's swallow better?
This trial tests if a rhythmic sound cue can reduce rolling (a swallowing problem) in people with Parkinson's. If you have trouble with solid foods but not severe liquid aspiration, you may qualify.
Saint-Sébastien-de-Morsent, NormandyAges 18 years+ - NCT05140993Recruiting
Emotional and orientation support to prevent delirium after surgery
This study tests whether extra emotional help and re-orienting (helping you know where you are and what’s happening) can lower the risk of confusion called postoperative delirium after surgery. It is designed for older adults having certain types of non-heart, non-brain surgery.
Tel AvivAges 70–120 - NCT05254730Recruiting
Testing brain-recording sensors to map the seizure source
This study looks at using special tiny filaments during brain monitoring to better identify where seizures start. It’s meant for people with hard-to-control (refractory) epilepsy who are already being considered for a specific brain-monitoring procedure.
Montreal, QuebecAges Any age
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,941 recruiting neurology studies from the U.S. registry right now, out of 18,432 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.