Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,420 recruiting studies in this area right now.
By phase
- Not applicable9,752
- Phase 2783
- Phase 1576
- Phase 3536
- Phase 4343
- Phase 1/Phase 2307
- Phase 2/Phase 3123
Top conditions
- Stroke844
- Parkinson Disease426
- Alzheimer Disease342
- Multiple Sclerosis341
- Dementia227
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea156
- Insomnia155
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment130
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California679
- Massachusetts300
- New York292
- Florida275
- Texas266
- Maryland246
- Arizona213
- Alabama210
- Illinois187
- Pennsylvania178
Recruiting studies12,418 total
- NCT07737431Recruiting
Wrist-hand rehab device test for stroke survivors
This trial tests a new device that combines sensor and muscle signals to help you control wrist and hand movements after a stroke. It aims to improve your coordination and function.
Hung Hom, KowloonAges 30–70 - NCT06284161Recruiting
QCT scan for ALS diagnosis and monitoring
This study uses quantitative computed tomography (QCT), a special type of CT scan, to help diagnose ALS, understand how it affects the body, and track its progression over time. It is for people who may have ALS and meet specific diagnostic criteria.
Clermont-FerrandAges 18 years+ - NCT07699029Recruiting
Clot removal for stroke in the back of the brain after 24 hours
This study tests a procedure to remove blood clots from large arteries in the back of the brain up to 14 days after a stroke starts. It may help people who have had a stroke more than a day ago and still have significant disability.
Wuhan, HubeiAges 18 years+ - NCT05563792Recruiting
Non-drug options for managing chronic pain
This study tests non-drug treatments for chronic pain in the back, neck, or joints. It aims to help people manage pain and improve daily function without relying on medications.
Indianapolis, IndianaAges 18 years+ - NCT07735910Recruiting
Binaural beats for memory in older adults with mild cognitive impairment
This trial tests whether listening to special sounds called binaural beats can help older adults with mild memory or thinking problems improve their cognitive function. If you live in a nursing home and have mild cognitive impairment (not dementia), you may be able to join.
Shenyang, LiaoningAges 60 years+ - NCT07737873Recruiting
Movement and brain function after chronic stroke
This study looks at how stroke affects your movement and nervous system over time. You will do simple movement tests and answer quality-of-life surveys to help researchers understand how to improve recovery.
Sacramento, CaliforniaAges 18 years+ - NCT04657068RecruitingPhase 1/Phase 2
Study of ART0380 for advanced solid tumors
This study tests a new drug called ART0380 for people with advanced solid tumors that have not responded to standard treatments. It may be especially helpful for those with certain DNA repair gene changes (like ATM or BRCA). The drug will be given alone or with chemotherapy (gemcitabine or irinotecan) depending on the part of the trial.
Birmingham, AlabamaAges 18 years+ - NCT07736885Recruiting
Hand stimulation for thinking problems after stroke
This study tests a gentle, painless electrical stimulation on specific points on the hands to see if it helps improve thinking and memory after a stroke. It is for people who have had a stroke in the last 2 weeks to 6 months and are noticing some cognitive changes.
Tianjin, Tianjin MunicipalityAges 35–80 - NCT07273019Recruiting
Tongue muscle test for children with sleep breathing issues
This trial studies how tongue muscles work in children who have trouble breathing during sleep. It aims to understand the link between tongue function and sleep disorders, which may lead to better treatments.
BronAges 4–17 - NCT07736482Recruiting
How fatigue and disability affect obstacle stepping in MS
This study looks at how fatigue and disability affect your ability to step over an obstacle while walking—whether you are doing just that task or also doing a second task (like talking). It may help understand how MS affects everyday movement.
Afyonkarahisar, MerkezAges 18–65 - NCT06479174Recruiting
Cognitive strategies after stroke with family support
This study tests if combining cognitive exercises with a safe, mild brain stimulation can help improve memory and thinking after a stroke. It also looks at how shared family health history might affect recovery.
Albuquerque, New MexicoAges 18 years+ - NCT07032662RecruitingPhase 2
Testing Imeroprubart for adults with CIDP
This trial tests a new drug called Imeroprubart for people with CIDP who are already on a stable treatment like steroids or immunoglobulin. The goal is to see if the drug can help control symptoms better.
Tucson, ArizonaAges 18 years+ - NCT07257302Recruiting
Breathing muscle training for ALS patients
This study tests whether a special breathing exercise called Lung Insufflation Capacity (LIC) training can help people with ALS maintain or improve their breathing muscle strength. Participants must be age 20 or older, have a confirmed ALS diagnosis, and not be using a breathing machine at the start of the training.
Kodaira, TokyoAges 20 years+ - NCT05032053Recruiting
Blood thinner use after stroke in people with small bleeds
This trial studies whether using blood-thinning medicine is safe and appropriate for people after an ischemic stroke who also have small signs of bleeding in the brain. It aims to balance stroke prevention with the risk of bigger bleeding.
Ankang, ShaanxiAges 40 years+ - NCT04743141RecruitingPhase 3
Long-term migraine medicine study for kids with migraine attacks
This Phase 3 study checks the long-term safety of rimegepant, a migraine treatment, in children and teens. You might join if your child has had migraine for at least 6 months and still gets a certain number of moderate-to-severe migraine attacks.
Scottsdale, ArizonaAges 6–17 - NCT06578195Recruiting
Assess all ALS study
This study follows people with ALS and healthy volunteers over time to understand the disease better. You can join from home using a smartphone or computer.
Birmingham, AlabamaAges 18 years+ - NCT07517263RecruitingPhase 3
Long-term Safety Study of Pelacarsen Treatment
This study follows patients who completed an earlier pelacarsen trial to check if the treatment remains safe and well-tolerated over time. Pelacarsen is an experimental medicine being tested for heart and cholesterol health.
Andalusia, AlabamaAges 18–100 - NCT06991101RecruitingPhase 2
Ruxolitinib with radiation and chemo for new glioblastoma
This trial tests adding ruxolitinib, a targeted drug, to the standard radiation and chemotherapy for newly diagnosed glioblastoma. It aims to see if this combination helps people live longer without their cancer growing.
Miami, FloridaAges 18 years+ - NCT07345702Recruiting
Endovascular therapy for large core posterior stroke
This trial tests endovascular therapy (a procedure to remove a clot through a tube in an artery) versus medical management for people with a severe stroke due to a blockage in the back part of the brain (basilar artery) and a large area of brain damage. The goal is to see if the procedure improves outcomes compared to medication alone.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07226141RecruitingPhase 1/Phase 2
Valproate for persistent lazy eye in children and teens
This trial tests if the medication valproate (a seizure drug) can improve vision in children and teens aged 8-17 who still have a lazy eye (amblyopia) even after wearing glasses or patching. It may help if your child's vision has stopped getting better with standard treatments.
Boston, MassachusettsAges 8–17 - NCT07688746RecruitingPhase 1
Helping premature babies heal brain injury
This trial tests a treatment for brain injury in premature babies born before 32 weeks. It aims to protect and repair white matter, the part of the brain that helps nerve cells communicate.
San Francisco, CaliforniaAges 3 weeks–5 months - NCT07227779RecruitingPhase 2
B-PaLMZ for TB meningitis in people with HIV
This trial tests a combination of TB medicines (B-PaLMZ) for people with HIV who have their first episode of TB meningitis. It aims to find a better treatment option.
KampalaAges 18 years+ - NCT07082725RecruitingPhase 3
Study of oral nizubaglustat for Niemann-Pick type C
This study tests an oral medication called nizubaglustat for people with Niemann-Pick type C disease who cannot take or are not satisfied with the current treatment miglustat. It aims to see if the drug can help with symptoms like coordination and movement problems.
Oakland, CaliforniaAges 4 years+ - NCT07492680RecruitingPhase 2
Study of BMS-986504 for solid tumors with MTAP deletion
This trial tests an experimental drug called BMS-986504, given alone or with other drugs, for people with advanced solid tumors that have a specific genetic change called a homozygous MTAP deletion. It may be an option if standard treatments are no longer working or aren't available.
San Francisco, CaliforniaAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,420 recruiting neurology studies from the U.S. registry right now, out of 19,378 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.