Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,941 recruiting studies in this area right now.
By phase
- Not applicable9,343
- Phase 2764
- Phase 1557
- Phase 3513
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke796
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis329
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management114
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California659
- Massachusetts305
- New York294
- Florida271
- Texas266
- Maryland248
- Alabama207
- Arizona207
- Illinois181
- Pennsylvania176
Recruiting studies11,941 total
- NCT05968664Recruiting
Test whether new spinal cord stimulation settings improve chronic pain
This trial studies whether changing the “stimulation pattern” of spinal cord stimulation can reduce long-lasting pain and improve daily function. You might be a good candidate if you have chronic trunk or leg pain and have already tried multiple pain treatments without enough relief.
Houston, TexasAges 22 years+ - NCT06201598Recruiting
Treatment for brain aneurysms with flow-diverter stents
This study is testing if a type of stent called a flow-diverter is safe and effective for treating brain aneurysms. It may help patients who have an aneurysm that was found by chance, is causing symptoms, or has already ruptured.
A CoruñaAges 18 years+ - NCT06081946Recruiting
Does broken sleep affect itch and pain sensitivity?
This study looks at how a poor night's sleep (short, broken sleep) affects your sensitivity to itching and pain. The goal is to understand if sleep problems might make skin conditions worse.
AalborgAges 18–60 - NCT06389968Recruiting
Light therapy for vision after optic neuritis in MS
This study tests whether light stimulation can help improve vision after optic neuritis in people with multiple sclerosis. It may offer a way to support eye recovery without medication.
Munich, BavariaAges 18–60 - NCT06245694Recruiting
Emergency room study for neurological deficits
This trial uses advanced data analysis to help doctors in the emergency room better predict and treat neurological problems like stroke or brain injury. It aims to improve care for all adults who come to the ER with these issues.
ViennaAges 18–120 - NCT06283745Recruiting
Platelet-rich plasma nasal injection for smell distortion
This trial tests whether injecting a concentrated part of your own blood (platelet-rich plasma) into your nose can help improve a distorted sense of smell called parosmia. You will also do smell training at home, which is the current standard care.
Palo Alto, CaliforniaAges 18 years+ - NCT04233788Recruiting
Brain mass imaging study using MRI to learn what causes it
This study uses MRI scanning to better describe a suspected brain mass and understand what it might be. You may be asked to lie in the scanner for about one hour, if you meet the study’s safety and eligibility rules.
BernAges 18 years+ - NCT06702085Recruiting
Lifestyle changes for older adults with tinnitus and metabolic syndrome
This study tests whether lifestyle changes (like diet and exercise) can help older adults who have both metabolic syndrome and chronic tinnitus (ringing in the ears). It is for people 65 and older with class 1 obesity and long-term ear ringing in both ears.
Dokki, Giza GovernorateAges 65–75 - NCT06696469Recruiting
Virtual reality for arm recovery after stroke
This trial tests if a virtual reality system called BeCure can help people who had a stroke recover arm movement. It's for people who are still in the early to later stages of recovery (not the very first days) and have some movement and sitting balance.
AnkaraAges 18–80 - NCT06701396RecruitingPhase 3
Tasimelteon for delayed sleep phase disorder with genetic variant
This study tests a new sleep medication called tasimelteon compared to a placebo (inactive treatment) for people with a specific sleep disorder linked to a genetic change in the body's internal clock. If you have Delayed Sleep-Wake Phase Disorder and carry the CRY1Δ11 variant, this trial may help improve your sleep timing.
Çankaya, AnkaraAges 18–75 - NCT03745534Recruiting
Cochlear implant after Gamma Knife for vestibular schwannoma
This pilot study looks at how well cochlear implants work for hearing restoration in people who previously received Gamma Knife treatment for a tumor called vestibular schwannoma. It may help doctors understand what hearing results to expect after surgery.
Vienna, State of ViennaAges 18 years+ - NCT03745560Recruiting
Test hearing testing during surgery to guide cochlear implant decisions
This study uses a special hearing test done during surgery for vestibular schwannoma to help decide what hearing treatment you need afterward. It may help guide whether a cochlear implant is a good option for hearing rehabilitation.
Vienna, AustriaAges 18–99 - NCT03890861Recruiting
Exercise program to help lower Alzheimer’s risk
This trial studies whether a structured group exercise program can help lower Alzheimer’s disease risk in older African Americans. You would be assigned to a group by chance and asked to attend regular sessions if it’s safe for you to exercise.
Baton Rouge, LouisianaAges 60 years+ - NCT03953768Recruiting
Testing a new vagus nerve stimulator for gut and immune health
This study looks at what happens to your immune system and stomach/gut function after getting a vagus nerve stimulator (VNS) for the first time for epilepsy. It may help doctors understand whether the device benefits more than seizures.
Louisville, KentuckyAges birth–60 years - NCT04331392Recruiting
Online memory training for people with recent brain injury
This trial tests an online memory program for people with a recent traumatic brain injury (TBI) to help with thinking and memory. It may be useful if your injury is recent and you can safely do MRI scanning.
Toronto, OntarioAges 18–55 - NCT05623124Recruiting
Alzheimer’s and dementia brain and memory study with caregiver support
This is a study that enrolls people with mild Alzheimer’s-related memory problems or dementia to help build a research “neurobank.” It also involves memory testing and may include brain scans, with a stable caregiver to support follow-up.
Shanghai, Shanghai MunicipalityAges 50–90 - NCT05632757Recruiting
Studying support for ALS patients and their family caregivers
This study looks at how much burden (stress and day-to-day strain) ALS creates for both the patient and the main caregiver. It may help shape better ways to support families facing ALS over time.
MarseilleAges 18 years+ - NCT06702826RecruitingPhase 2
Cadonilimab plus radiation for lung cancer brain mets
This trial tests a combination of a targeted immunotherapy drug (cadonilimab) with a precise type of radiation to treat brain tumors that have grown after initial lung cancer treatment. The goal is to see if this approach can safely shrink brain metastases and improve outcomes.
Changsha, HunanAges 18–75 - NCT06229626Recruiting
Intensive home training for hereditary spastic paraparesis SPG4
This trial tests an intensive, video-based exercise program for people with a specific type of hereditary spastic paraparesis (SPG4). It aims to see if adding extra training at home can improve walking and strength.
ParisAges 18 years+ - NCT06362304Recruiting
New SPECT imaging for brain tumors
This trial tests a new imaging agent (99mTc-CNDG) to see if it can help doctors see brain tumors better on a SPECT/CT scan. It might provide more information than standard scans and could help guide treatment decisions.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06702904Recruiting
Neuroprosthesis for phantom limb pain relief
This study tests a new type of artificial limb (neuroprosthesis) that sends signals back to your brain to help reduce phantom limb pain and improve your daily life. You may be able to join if you have had an arm or leg amputation at least 6 months ago and have persistent pain.
MoscowAges 18–65 - NCT06070766Recruiting
At-home ketamine study for chronic conditions
This trial tests a ketamine protocol you can use at home. It may help if you have a long-term health condition.
Bigfork, MontanaAges 18 years+ - NCT06222866Recruiting
Blood thinner and inflammation monitoring after heart procedures
This study looks at how well blood thinners (anticoagulants) and inflammation markers work in people having heart or blood vessel procedures. It aims to better monitor these treatments to improve patient safety.
Innsbruck, TyrolAges 18 years+ - NCT06475118Recruiting
Blood tests and scans to measure muscle loss in liver cancer
This study looks at whether measuring certain proteins in your blood (myokines) can help detect muscle loss (sarcopenia) in people with liver cancer, and compares these blood tests to special CT scans. If you're newly diagnosed with liver cancer and have a CT scan already, you may be able to join.
ReimsAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,941 recruiting neurology studies from the U.S. registry right now, out of 18,432 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.