Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,764 recruiting studies in this area right now.
By phase
- Not applicable1,204
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 285
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- National Taiwan University Hospital16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona68
- Florida43
- Maryland39
- Texas37
- New York36
- Massachusetts35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,764 total
- NCT07659626Recruiting
Long-term effects of Acoltremon for dry eye disease
This study tests a new medication called Acoltremon to see if it helps dry eye symptoms over a long period. If you've had dry eye for a while and used artificial tears, this trial might be for you.
Louisville, KentuckyAges 18 years+ - NCT03918408RecruitingPhase 1
Platinum eye drops and light to slow keratoconus
This Phase 1 study tests whether a specific corneal cross-linking system (called PXL-Platinum 330) is safe and effective for people with progressive keratoconus, a condition that makes the cornea thin and bulge. The goal is to slow vision changes and see how well the treatment works in the short term.
Eugene, OregonAges 12–45 - NCT07653269Recruiting
Tracking eye changes to predict AMD progression
This study uses eye imaging and other tests to predict if early age-related macular degeneration (AMD) will progress to a more advanced stage. It aims to help doctors identify who might need closer monitoring in the future.
SingaporeAges 55 years+ - NCT07649265RecruitingPhase 1
Testing a new drug for autoimmune diseases
This study tests a new drug called HBM7020 to see if it is safe and how well it is absorbed by the body. It is for healthy people and people with certain autoimmune diseases like lupus, scleroderma, rheumatoid arthritis, or Sjögren's disease.
Brisbane, QueenslandAges 18–75 - NCT07650708RecruitingPhase 4
Eye Dryness After LASIK Surgery With a New Dry Eye Treatment
This study tests whether a new eye lubricant called Miebo, given before LASIK vision correction surgery, reduces dry eye symptoms afterward. If you have mild-to-moderate dry eyes and need LASIK, this trial may help you stay more comfortable during your recovery.
Bozeman, MontanaAges 18 years+ - NCT07648355Recruiting
Vision outcomes with Clareon TruPlus lens implants
This study tests a new type of lens implant (Clareon TruPlus) used during cataract surgery. Researchers will measure how well patients see afterward and how satisfied they are with their vision.
Saint Louis Park, MinnesotaAges 18 years+ - NCT07648095Recruiting
Lacrifill treatment for dry eyes before cataract surgery
This trial tests whether a treatment called Lacrifill can help improve dry eye symptoms in patients preparing for cataract surgery. Lacrifill is designed to keep the eye surface moist and healthy during the surgical process.
Largo, FloridaAges 40 years+ - NCT07653074Recruiting
Vision and quality of life in youth with myopia or CVI
This study looks at how vision problems like nearsightedness (myopia) and a brain-based vision condition (CVI) affect daily life and well-being in children. It aims to understand what support they might need to thrive in a modern world.
ÖrebroAges Up to 17 years - NCT07653984Recruiting
Study on immune diseases in women of childbearing age
This study follows women with certain immune disorders affecting the nervous system (like multiple sclerosis or myasthenia gravis) to understand how these conditions affect reproduction. Healthy women planning pregnancy are also included for comparison.
Guangzhou, GuangdongAges 20–55 - NCT06686472RecruitingPhase 2
Testing TL-925 eye drops for allergic conjunctivitis
This trial tests an investigational eye drop called TL-925 to see if it can treat allergic conjunctivitis (eye allergies). If you have a history of eye allergies and a positive allergy skin test, you may be able to join.
Memphis, TennesseeAges 18 years+ - NCT06141460RecruitingPhase 1/Phase 2
Gene therapy trial for wet age-related macular degeneration
This trial tests a new gene therapy called RRG001 for people with the 'wet' form of age-related macular degeneration. It aims to treat leaky blood vessels in the eye that can cause vision loss, possibly reducing the need for frequent eye injections.
Tianjin, Tianjin MunicipalityAges 50 years+ - NCT06691555Recruiting
Long-term safety of a silicone tube eye implant
This study follows up with people who have previously received a special silicone tube implant in their eye to see how they are doing over time. It aims to check the long-term safety and how well the implant is working.
TbilisiAges 40–90 - NCT07638215Recruiting
Hydrogel for corneal wound repair
This study tests a new hydrogel glue that helps heal a damaged cornea (the clear front part of the eye) without needing stitches. It may help people with certain corneal defects from injury or after surgery.
Jinan, ShandongAges 18–85 - NCT07642960Recruiting
Fine-needle Heat Treatment Plus Eye Injection for Corneal Blood Vessel Growth
This trial tests a combination of two treatments—a heat procedure and a medication injection—to reduce abnormal blood vessel growth on the clear front surface of your eye (cornea). The goal is to improve your vision and prevent further damage.
Ho Chi Minh City, Xuan HoaAges 18 years+ - NCT07640997Recruiting
Real-world study of aflibercept for age-related macular degeneration
This study follows patients receiving aflibercept 8 mg injections in the eye to treat wet age-related macular degeneration (nAMD), a condition that blurs central vision. The goal is to understand how well this treatment works and its safety in routine medical practice.
Beijing, Beijing MunicipalityAges 50 years+ - NCT07642999Recruiting
How Children's Screen Time Affects Eye Development
This study tracks how much time children spend looking at screens versus outdoor activities and how that relates to their eye health over 3 years. Researchers will give your child a special device to wear at home to measure their visual habits.
New York, New YorkAges 7–12 - NCT07638943Recruiting
Switching multifocal contact lenses to improve comfort
This study compares two brands of multifocal contact lenses (lenses that help you see at multiple distances) in people over 40 who are currently happy with their INFUSE One-Day Multifocal lenses. Researchers want to see if switching to DAILIES TOTAL1 Multifocal lenses provides similar or better comfort and vision.
La Jolla, CaliforniaAges 40 years+ - NCT07642687Recruiting
Eye Muscle Training for Outward-Turning Eyes in Young People
This study tests whether a special near-vision training exercise can help improve control of eyes that turn outward (a condition called intermittent exotropia). The training focuses on the eye muscles' ability to work together at different distances, and may help reduce the need for surgery.
Hong KongAges 6–25 - NCT07636590Recruiting
Study of vision changes in limbal stem cell deficiency
This observational study follows patients with limbal stem cell deficiency (a condition affecting cells at the edge of the cornea that help maintain healthy eye surface) to understand how their vision changes over time. Researchers will track your eye health without giving you new treatment.
Carmel, IndianaAges 12–99 - NCT07629557RecruitingPhase 4
Same-Day Corneal Cross-Linking for Keratoconus in Both Eyes
This study tests a same-day procedure that strengthens the cornea (the clear front part of the eye) in both eyes using a special light treatment, called cross-linking. It may help slow or stop the progression of keratoconus, a condition where the cornea becomes cone-shaped and causes blurry vision.
Westerville, OhioAges 13 years+ - NCT07636785RecruitingPhase 1/Phase 2
VMD-102 Drug Study for Advanced Cancers
This study tests a new drug called VMD-102 in patients with advanced liver cancer, melanoma, kidney cancer, lung cancer, or colon cancer that hasn't responded to standard treatments. The trial will help determine if VMD-102 is safe and effective at slowing or stopping cancer growth.
Scottsdale, ArizonaAges 18–75 - NCT07630649RecruitingPhase 2
Gene therapy for wet age-related macular degeneration in second eye
This study tests a one-time gene therapy injection (ixoberogene soroparvovec) in the second eye of people with wet age-related macular degeneration who have already responded well to anti-VEGF injections. The goal is to see if this gene therapy can help preserve or improve vision in that eye.
Phoenix, ArizonaAges 50 years+ - NCT07634913Recruiting
Mobile App for Eye Disease Detection
This study tests a smartphone-based system designed to help detect diseases affecting the front of the eye. Researchers will develop and refine this mobile tool to see if it can accurately identify common eye conditions using photos taken on a phone or with standard eye-examination equipment.
Guangzhou, GuangdongAges 18 years+ - NCT07635329Recruiting
Home Vision Therapy Guided by Brain Scans
This study tests whether vision rehabilitation exercises done at home, guided by brain imaging, can help people regain vision after a stroke, brain injury, or tumor. Participants will use brain scans to personalize their therapy.
Washington D.C., District of ColumbiaAges 18 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,764 recruiting ophthalmology studies from the U.S. registry right now, out of 2,747 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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- Genetic & congenital
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- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.