Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,819 recruiting studies in this area right now.
By phase
- Not applicable1,253
- Phase 3132
- Phase 2121
- Phase 1120
- Phase 492
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract89
- Myopia89
- Diabetic Retinopathy52
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Ocular Hypertension22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California141
- Arizona66
- Texas41
- Maryland39
- Massachusetts34
- New York34
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania20
Recruiting studies1,819 total
- NCT06826573Recruiting
Risk factors for eye pressure and retinal detachment after surgery
This study looks at why some patients develop high eye pressure or retinal detachment again after surgery to repair retinal detachment with silicone oil. It aims to find risk factors so doctors can better prevent these complications.
Chongqing, Chongqing MunicipalityAges 18–90 - NCT07149259Recruiting
Testing eSight Go at home for vision loss
This trial tests whether using eSight Go electronic glasses at home can help people with vision impairment see better in daily life. You wear the device while doing normal activities to see if it improves your vision and quality of life.
Jacksonville, FloridaAges 18–90 - NCT06808295RecruitingPhase 1
Dexmedetomidine for tear duct surgery
This study tests whether a medication called dexmedetomidine can reduce the amount of anesthesia needed during tear duct surgery (DCR), possibly making the procedure safer and more comfortable.
GizaAges 16–75 - NCT06803082Recruiting
How systemic light chain amyloidosis affects the eyes
This study looks at how systemic light chain amyloidosis, a condition where abnormal proteins build up in organs, may affect your eyes. By comparing eye exams of people with and without the disease, researchers hope to learn more about eye-related changes so they can improve care.
Guangzhou, GuangdongAges 18–80 - NCT05685485Recruiting
Testing a tube implant surgery for certain glaucoma
This trial studies a glaucoma operation that uses an Ahmed valve tube implant. It may help people whose eye pressure is not well controlled with current treatments by comparing outcomes of this specific surgical approach.
St Louis, MissouriAges 18 years+ - NCT07400965RecruitingPhase 2
Testing a new eye drop for eyelid inflammation caused by tiny mites
This trial tests an investigational eye drop (GLK-321) to see if it safely and effectively treats Demodex blepharitis, an eyelid inflammation caused by tiny mites. It may help people who have signs of this condition and good enough vision.
Newport Beach, CaliforniaAges 18 years+ - NCT06672536RecruitingPhase 1/Phase 2
Study of SCT520FF for wet age-related macular degeneration
This trial tests an investigational drug called SCT520FF for people with wet age-related macular degeneration (nAMD). It aims to find the safest dose and check if it can improve vision. You may be eligible if you have active new blood vessels in your eye from nAMD and have not had certain other eye problems.
TianjingAges 45–80 - NCT07451184RecruitingPhase 4
Comparing eye drops for dry eye relief
This study compares two different eye drop lubricants to see which one works better for people with dry eye symptoms. You would use only the study drops for the whole time and attend a few visits to check your eyes.
Waterloo, OntarioAges 18 years+ - NCT07553429RecruitingPhase 1/Phase 2
Testing a new eye injection for diabetic swelling
This study tests different doses of a new medicine (BI 3812465) injected into the eye to treat diabetic macular edema—swelling in the back of the eye caused by diabetes that can blur vision. The trial measures how safe the medicine is and how well patients tolerate it.
Phoenix, ArizonaAges 18 years+ - NCT06714799Recruiting
Skin lesion analysis study for eye and eyelid growths
This study looks at skin growths near the eye using a special camera. It may help doctors better understand and diagnose these growths without needing a biopsy.
BolognaAges 18 years+ - NCT07547228RecruitingPhase 1/Phase 2
PRL3-zumab for advanced age-related macular degeneration
This study tests a new injectable medicine called PRL3-zumab for patients with advanced wet macular degeneration (nAMD) whose condition hasn't improved enough with standard treatments. The goal is to see if this new approach can help preserve or improve vision in people who have already tried at least two other eye injections.
SingaporeAges 18 years+ - NCT06650306Recruiting
Soft contact lenses and eye health in high myopia
This study looks at how wearing soft contact lenses affects the cornea and vision quality in people with high myopia before they have SMILE laser surgery. It may help doctors understand how to better prepare patients for the procedure.
Shanghai, Shanghai MunicipalityAges 18–45 - NCT06651736Recruiting
Low vision rehab for people with inherited eye disease and distress
This study tests a 10-week low vision rehabilitation program for people with inherited retinal diseases who also feel emotionally distressed. The goal is to see if the program improves daily function and emotional well-being.
Ann Arbor, MichiganAges 18 years+ - NCT07378657RecruitingPhase 3
Sirolimus for children with orbital malformation
This trial tests if sirolimus can help children with a certain type of eye socket malformation. It aims to find a better treatment for children aged 1 to 18.
Cairo, Cairo GovernorateAges 1–18 - NCT04521673Recruiting
Detecting causes of infectious eye inflammation
This trial looks for germs causing eye inflammation (uveitis) that may be due to an infection. It could help identify the best treatment for your condition.
ShanghaiAges Any age - NCT06596408Recruiting
Blood vessel study in very nearsighted eyes
This study uses OCTA, a type of eye scan, to look at the blood vessels in the back of the eye in people who are very nearsighted (high myopia). It aims to understand how high myopia affects the retina's blood supply, which could help with future eye care.
Sohag, Sohag GovernorateAges 15 years+ - NCT05156151Enrolling by invitation
Lenticule Implant for Herpes-Related Cloudy Cornea
This trial implants a small lens-shaped tissue (called a lenticule) into the cornea to help restore its clarity and improve vision in people with vision problems from repeated herpes infections. If you've had ongoing issues with herpes in your eye, this treatment might reduce scarring and help you see better.
PristinaAges 21–46 - NCT07277257RecruitingPhase 4
New dry eye treatment for people with Sjögren's syndrome
This study tests a new treatment for dry eye disease caused by Sjögren's syndrome. It may help people who still have dry eye symptoms even when using artificial tears.
Venice, FloridaAges 18 years+ - NCT06565572Enrolling by invitationEarly Phase 1
Antisense drug for PCARP disease caused by FLVCR1 mutation
This trial tests a new drug called an antisense oligonucleotide (a type of genetic medicine) for people with a specific form of inherited eye disease called PCARP, which is caused by changes in the FLVCR1 gene. The goal is to see if the drug can slow or stop vision loss.
Aurora, ColoradoAges Any age - NCT06539481RecruitingPhase 4
ILUVIEN eye implant for kids with recurrent eye inflammation
This trial tests an eye implant (ILUVIEN) in children and teens ages 6 to 17 who have a type of eye inflammation called uveitis that keeps coming back. The implant releases medicine slowly over time to control inflammation and may help reduce the need for other treatments.
BerlinAges 6–17 - NCT07666984RecruitingPhase 4
Effect of two reversal drugs on optic nerve sheath size
This trial compares two medications given after surgery to see how they affect the size of the sheath around your optic nerve, which can show changes in brain pressure. It helps doctors understand which medication might be safer for your eyes and brain.
AdanaAges 18–65 - NCT07314411Recruiting
Carotenoids for Eye Health in Healthy Adults
This study tests if taking a carotenoid supplement (MacuHealth) can improve or protect retinal health in healthy adults. You might join if you have normal vision and no major eye or health problems.
Forest Grove, OregonAges 18–75 - NCT06536491RecruitingPhase 1/Phase 2
EC-104 eye implant for diabetic macular edema
This early-phase trial tests a new implant (EC-104) that goes inside the eye to treat diabetic macular edema (DME), a condition that causes blurry vision from fluid buildup. The implant slowly releases medicine over time, and the study will see if it is safe and helpful for people with DME.
Tampa, FloridaAges 18 years+ - NCT06529367Recruiting
Home vs. Office Eye Test for Nearsighted Children
This study checks whether a simple home vision test can give results as accurate as the standard eye chart test done in a doctor's office. It is for children who are nearsighted and have already completed both a home test and an office test.
QinaAges Up to 18 years
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,819 recruiting ophthalmology studies from the U.S. registry right now, out of 2,909 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.