Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,819 recruiting studies in this area right now.
By phase
- Not applicable1,253
- Phase 3132
- Phase 2121
- Phase 1120
- Phase 492
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract89
- Myopia89
- Diabetic Retinopathy52
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Ocular Hypertension22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California141
- Arizona66
- Texas41
- Maryland39
- Massachusetts34
- New York34
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania20
Recruiting studies1,819 total
- NCT06498947Recruiting
Understanding Natural Farsightedness in Kids
This study looks at natural changes in children's eyes that cause mild farsightedness (called "physiological hyperopia") in 6- to 9-year-olds. It aims to understand why some children have this harmless vision difference, which may help with future eye care.
Beijing, Beijing MunicipalityAges 6–9 - NCT06013462Recruiting
Corneal transplant after earlier eye surgery
This trial tests a type of corneal transplant (DMEK) in people who have had previous eye surgeries, such as vitrectomy or glaucoma surgery. It aims to see if the transplant works well even in these complicated cases.
ParisAges 18 years+ - NCT06492876RecruitingPhase 1/Phase 2
Gene therapy trial for diabetic macular edema (DME)
This trial tests a gene therapy for diabetic macular edema (DME), a condition where fluid builds up in the central part of the eye's retina. It aims to improve vision and reduce the need for frequent eye injections.
Tianjin, Tianjin,ChinaAges 18–74 - NCT02886611Recruiting
Study for genetic eye surface stem cell problems
This trial studies people whose eye surface problems are caused by an inherited (genetic) condition. It aims to better understand how specific genetic changes relate to symptoms, which may guide more personalized care.
ParisAges Any age - NCT06294613Recruiting
Robotic surgery for vitreoretinal diseases
This trial tests a robotic system for eye surgery to treat conditions like vitreous hemorrhage or macular pucker. It may help patients who need a procedure called vitrectomy under general anesthesia.
Ghent, East FlandersAges 18–85 - NCT07338097Enrolling by invitation
Comparing two eye injections for diabetic macular edema
This study tests whether one eye injection (aflibercept) works better than another (bevacizumab) for people with diabetic macular edema. Both are already used for this condition, and the goal is to see which provides better vision improvement.
Multan, Punjab ProvinceAges 30–60 - NCT07307469Enrolling by invitation
Extended access to ZVS101e for BCD patients
This trial offers compassionate use of the gene therapy ZVS101e for people with Bietti crystalline dystrophy (BCD) who were in the control group of an earlier study. It aims to give extended treatment access to those who didn't receive the experimental therapy before.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06990269RecruitingPhase 2
Study of ADX-038 for geographic atrophy in dry AMD
This trial tests an investigational drug (ADX-038) for people with geographic atrophy, a form of advanced dry age-related macular degeneration. The drug is given as an injection into the eye, and the study checks if it can slow down the growth of GA spots.
Gilbert, ArizonaAges 60 years+ - NCT07329777RecruitingPhase 3
Atropine eye drops for children with worsening nearsightedness
This trial tests whether daily atropine eye drops can slow down worsening nearsightedness in children. It's for kids aged 5–10 whose myopia is actively progressing.
Kuala Lumpur, CherasAges 5–10 - NCT06364878Recruiting
Non-invasive diagnosis for eye infections
This study tests a new, non-invasive (no needles or surgery) way to diagnose a type of eye infection called microbial keratitis. It may help find the cause faster so you get the right treatment sooner.
ArendalAges 18 years+ - NCT06351605Recruiting
Light therapy study for dry age-related macular degeneration
This study tests a light-based treatment (photobiomodulation) for dry AMD, using the Valeda Light Delivery System. It may help improve vision and eye health over time.
OsloAges Any age - NCT07235085RecruitingPhase 3
Study of OTX-TKI implant for moderate to severe NPDR
This study tests an eye implant (OTX-TKI) that slowly releases a medicine to slow or stop worsening of non-proliferative diabetic retinopathy (NPDR) — an early form of diabetic eye disease. It's for people with moderately severe to severe NPDR who haven't had significant treatments like laser or injections in that eye.
Hagerstown, MarylandAges 18 years+ - NCT06269419Recruiting
Diabetes eye disease natural progression study
This study follows people with type 2 diabetes to understand how diabetic retinopathy (an eye disease caused by diabetes) changes over time without treatment. It may help if you have no other eye issues causing new blood vessels and are not planning for certain eye procedures.
Chengdu, SichuanAges 18–75 - NCT06190301Recruiting
Comparing injection vs. radiation for eye lymphoma
This trial compares two treatments for a slow-growing eye lymphoma called MALT lymphoma: a targeted injection (rituximab) directly into the tumor versus low-dose radiation. The goal is to see which is safer and works better, while avoiding whole-body side effects.
Guangzhou, GuangdongAges 18–75 - NCT06165068RecruitingPhase 3
Antiplatelet and antioxidant drugs for dry AMD with drusen
This study tests whether antiplatelet drugs (like aspirin) and antioxidants can slow the growth of drusen (yellow deposits) in dry age-related macular degeneration (AMD). It may help prevent the disease from worsening.
Bangkok, DusitAges 50–85 - NCT07295704Recruiting
Micropulse laser for diabetic macular edema
This trial tests a special laser treatment for diabetic macular edema, a swelling in the back of the eye caused by diabetes. It aims to see if the laser can help patients who have not improved with standard treatment.
CairoAges 18 years+ - NCT07006428Recruiting
Comparing two types of multifocal lens implants for cataract surgery
This trial compares the Clareon PanOptix lens with another similar multifocal lens to see which provides better vision after cataract surgery. It has two stages: one for people who already had the lenses implanted, and one for those who are planning to have cataract surgery.
Torrance, CaliforniaAges Any age - NCT06942520RecruitingPhase 2
Gene therapy for diabetic macular edema in adults
This trial tests a gene therapy called RGX-314 for people with diabetic macular edema that affects the center of the vision. If you have had previous treatment and still have swelling, this study may be an option.
Reno, NevadaAges 25–89 - NCT07063719Recruiting
Finding cell markers for rare eye diseases in adults
This study looks for biological markers in the blood or eye samples of people with rare eye diseases compared to healthy volunteers. It aims to better understand and diagnose these conditions.
ParisAges 18 years+ - NCT07323251Recruiting
Do special glasses slow down myopia in children?
This study tests whether new spectacle lenses (glasses) can slow down the progression of nearsightedness (myopia) in children. It may be a good option if your child's myopia is getting worse and you want to try a non-invasive approach.
BeijingAges 6–14 - NCT06275308Recruiting
Testing carbon dioxide levels on eye structure in children
This study looks at how changing the level of carbon dioxide in the blood affects a layer in the back of the eye (the choroid) in children having an eye exam under anesthesia. It may help doctors understand eye health better.
Pittsburgh, PennsylvaniaAges Up to 8 years - NCT07025707Recruiting
Comparing two ways to measure lens position after cataract surgery
This trial compares two methods for calculating how much an artificial lens tilts or shifts after cataract surgery. It aims to find which method gives more accurate measurements.
Vienna, State of ViennaAges 21 years+ - NCT04205916RecruitingPhase 4
Preference trial of eye drops versus no-drops after cataract surgery
This trial compares two ways to prevent inflammation and comfort you after cataract surgery: usual antibiotic/steroid eye drops versus a “no-drops” option that is placed during surgery. It mainly looks at patient preference, comfort, and ease of treatment after surgery.
Garden City, New YorkAges 22–100 - NCT07213167Recruiting
Low contrast vision test for different lens implants
This trial checks how well you see in low light and low contrast after having cataract surgery with specific lens implants. It helps doctors understand which lenses work best in dim conditions.
Bakersfield, CaliforniaAges 22 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,819 recruiting ophthalmology studies from the U.S. registry right now, out of 2,909 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.