Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,764 recruiting studies in this area right now.
By phase
- Not applicable1,204
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 285
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- National Taiwan University Hospital16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona68
- Florida43
- Maryland39
- Texas37
- New York36
- Massachusetts35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,764 total
- NCT07634991RecruitingPhase 4
N-acetyl Cysteine for Diabetic Eye Disease
This study tests whether a supplement called N-acetyl cysteine can help slow or improve mild to moderate diabetic eye disease (diabetic retinopathy). The goal is to see if it's safe and effective for people with type 2 diabetes.
CairoAges 18–70 - NCT07634913Recruiting
Mobile App for Eye Disease Detection
This study tests a smartphone-based system designed to help detect diseases affecting the front of the eye. Researchers will develop and refine this mobile tool to see if it can accurately identify common eye conditions using photos taken on a phone or with standard eye-examination equipment.
Guangzhou, GuangdongAges 18 years+ - NCT07636876Enrolling by invitation
Italian MS and Related Disorders Patient Registry
This is a registry study that collects health information from people with multiple sclerosis and related conditions. By joining, you help researchers better understand these diseases and improve future treatments.
Genova, GenovaAges Any age - NCT07635329Recruiting
Home Vision Therapy Guided by Brain Scans
This study tests whether vision rehabilitation exercises done at home, guided by brain imaging, can help people regain vision after a stroke, brain injury, or tumor. Participants will use brain scans to personalize their therapy.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06694103Recruiting
Two ways to reduce pain during a baby's eye exam
This study tests two drug-free methods to help reduce pain when premature babies get a special eye exam for retinopathy of prematurity. It may help your baby feel more comfortable during the procedure.
Izmir, MenemenAges 6 months–8 months - NCT06694051Recruiting
Light treatment to mark astigmatism axis
This trial uses a special laser treatment to mark the exact axis of astigmatism for better correction. It might help patients with astigmatism get more precise treatment.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT07622121RecruitingPhase 3
Treatment for long-term thyroid eye disease
This trial tests a new medication for people with long-term thyroid eye disease that has lasted over a year. The aim is to see if it can reduce symptoms like bulging and discomfort.
Coral Gables, FloridaAges 18–75 - NCT07629232Recruiting
Study of corneal thickness and shape measurements
This study measures how light passes through the clear front part of your eye (cornea) using a specialized camera. These measurements help doctors better understand eye health and may improve future eye care.
Bonn, North Rhine-WestphaliaAges 18 years+ - NCT07623668RecruitingPhase 3
Testing a new drug for sudden vision loss from nerve inflammation
This study tests whether a new medication called privosegtor can help restore vision in people who recently experienced sudden vision loss in one eye due to optic nerve inflammation. You would receive the study drug early after your symptoms start, when treatment may be most effective.
Livonia, MichiganAges 18–50 - NCT07627698RecruitingPhase 1/Phase 2
CAR-NK Cell Therapy for Advanced Melanoma
This trial tests engineered immune cells (CAR-NK cells) designed to target two markers found on melanoma cells. The goal is to help patients with melanoma that has spread or cannot be surgically removed and has not responded to or is unsuitable for standard treatments.
Shenzhen, GuangdongAges 18–75 - NCT07621809RecruitingPhase 3
Ianalumab versus placebo for Sjögren's disease with high symptom burden
This study tests whether a new drug called ianalumab can reduce dry mouth and other symptoms in people with Sjögren's disease—a condition where the immune system attacks moisture-producing glands. Participants will receive either ianalumab or a placebo (inactive injection) over 52 weeks to see if the drug helps.
Peoria, ArizonaAges 18 years+ - NCT07622108RecruitingPhase 3
Study of an investigational drug for active thyroid eye disease
This trial tests a new medicine called MHB018A for people with active thyroid eye disease (TED), a condition that causes the eyes to bulge and become inflamed. The study aims to see if the drug can reduce symptoms and improve eye appearance compared to a placebo.
Coral Gables, FloridaAges 18–75 - NCT07622368RecruitingPhase 1
Testing IBI3031 for Active Thyroid Eye Disease
This early-stage trial tests a new drug called IBI3031 to treat active thyroid eye disease (TED), a condition where the immune system attacks muscles and tissue around the eyes, causing swelling, bulging, and sometimes double vision. The study aims to see if this drug can reduce inflammation and improve symptoms.
Shenyang, LiaoningAges 18–75 - NCT06696625Recruiting
Nerve stimulation for dry eye relief
This trial tests if mild electrical pulses on the ear can reduce dry eye symptoms. If you have had dry eye for at least 6 months and meet certain eye test results, this non-drug treatment might help.
Beijing, Beijing MunicipalityAges 18–65 - NCT06697535RecruitingPhase 2
Study of JYP0061 for acute NMOSD attacks
This trial tests a new medication called JYP0061 for people with NMOSD who are currently experiencing a sudden worsening of symptoms (acute attack). It aims to see if the drug can help control the attack and improve outcomes.
Changsha, HunanAges 18–65 - NCT07624929Enrolling by invitation
Virtual Reality to Reduce Anxiety During Varicose Vein Treatment
This study tests whether wearing a virtual reality headset during varicose vein treatment (a minimally invasive laser procedure on your legs) can help reduce anxiety and pain. You'd use VR while the doctor treats the problematic veins under local anesthesia.
BydgoszczAges 18 years+ - NCT07623252Recruiting
Testing the 2022 optic neuritis diagnostic criteria
This study is checking whether a new 2022 set of diagnostic rules correctly identifies optic neuritis, which is inflammation of the nerve that connects your eye to your brain. If you've recently had vision problems and doctors suspect this condition, participating could help confirm the diagnosis and shape future care.
Nanning, GuangxiAges Any age - NCT07623382RecruitingEarly Phase 1
Stem Cell Treatment for Dry Eye Disease
This early-stage trial tests whether special cells derived from umbilical cord tissue can help treat dry eye disease. The treatment uses tiny particles called extracellular vesicles that may reduce eye dryness and improve comfort.
Xiamen, ChinaAges 18 years+ - NCT07628946Recruiting
Eye Disease Database Study with Advanced Imaging
This study is building a detailed database of images and information from people with various eye diseases, especially those involving inflammation or swelling. Researchers will use advanced cameras and tests to better understand these conditions and potentially improve treatments.
BeijingAges 3 years+ - NCT06174948Recruiting
CUE1 device for Parkinson's and related movement disorders
This trial tests a small device called CUE1 that gives gentle vibrations on the chest to help improve movement and balance in people with Parkinson's disease and similar conditions. It may help if you have trouble with walking or stability.
LondonAges 18 years+ - NCT06389968Recruiting
Light therapy for vision after optic neuritis in MS
This study tests whether light stimulation can help improve vision after optic neuritis in people with multiple sclerosis. It may offer a way to support eye recovery without medication.
Munich, BavariaAges 18–60 - NCT05093374RecruitingPhase 4
AI-guided care for wet age-related macular degeneration
This Phase 4 study tests an artificial-intelligence (AI) system used in real-world care for people with “wet” age-related macular degeneration. The goal is to help doctors monitor and treat the eye more accurately and safely over time.
Vienna, State of ViennaAges 50–100 - NCT06519266RecruitingPhase 3
Liver treatment with immunotherapy for uveal melanoma that spread to the liver
This trial tests whether adding a liver-directed therapy (PHP) to a combination of two immunotherapy drugs (ipilimumab and nivolumab) works better than the immunotherapy drugs alone for people whose uveal melanoma has spread to the liver.
GothenburgAges 18 years+ - NCT02669953Recruiting
Aflibercept injections for persistent wet macular degeneration
This trial studies whether aflibercept injections can help when “wet” age-related macular degeneration is recurring or not fully going away. It focuses on adults who have already had ranibizumab and still have measurable vision in the study eye.
ViennaAges 50 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,764 recruiting ophthalmology studies from the U.S. registry right now, out of 2,747 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.