Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,816 recruiting studies in this area right now.
By phase
- Not applicable1,253
- Phase 3130
- Phase 2121
- Phase 1120
- Phase 491
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract90
- Myopia89
- Diabetic Retinopathy52
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Macular Degeneration22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California141
- Arizona66
- Texas41
- Maryland39
- New York34
- Massachusetts33
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania21
Recruiting studies1,816 total
- NCT05959005Recruiting
Tracking early macular atrophy changes in the eye
This study focuses on people age 50+ with early “wasting away” changes in the macula (central retina) called atrophic lesions. It aims to better understand how these early changes progress and how they affect vision testing, which may help improve future treatments.
Salt Lake City, UtahAges 50 years+ - NCT05966467Recruiting
Patient registry for AQP4+ neuromyelitis optica on C5 inhibitors
This registry collects health and relapse information from adults with AQP4-positive NMOSD who are taking C5-blocking medicines to prevent long-term relapses. It helps researchers better understand treatment patterns and outcomes in real-world care.
Washington D.C., District of ColumbiaAges 18 years+ - NCT05976139Recruiting
Micropulsed laser for swelling in inherited retina conditions
This study tests whether a micropulsed laser can reduce swelling in the macula (central vision area) in people with inherited retinal diseases. It may help improve or stabilize vision-related swelling seen on detailed eye scans.
Rome, RMAges 18–80 - NCT05981950Recruiting
AI for diagnosing retinal diseases in real-world settings
This study tests how well an AI system can diagnose retinal diseases from eye photos. It might help if you need a quick and accurate diagnosis using standard eye imaging.
Beijing, Beijing MunicipalityAges 1–100 - NCT05982925Recruiting
Brain imaging study in multiple sclerosis
This study uses MRI scans to look at how multiple sclerosis affects the outer layer of the brain over time. It aims to learn more about the disease to help improve future treatments.
New York, New YorkAges 18 years+ - NCT05989620Recruiting
Long-term study of muscular dystrophy functions
This study tracks changes in muscle strength and breathing over time in people with certain types of muscular dystrophy. It helps researchers develop better tests to measure how the disease progresses.
Richmond, VirginiaAges 6–50 - NCT05999630RecruitingPhase 3
Artificial tears to prevent tear duct blockage during RAI therapy
This study tests if using artificial tears (eye drops that keep your eyes moist) can prevent tear duct blockage in people receiving high-dose radioactive iodine for thyroid cancer. If you qualify, you will use artificial tears during your treatment to see if they help keep your tear ducts open.
Nashville, TennesseeAges 18 years+ - NCT06000865Recruiting
Video game and exercise rehab for glaucoma
This trial tests if active video games and exercise can help people with glaucoma improve their balance and daily function. It's for people who have stable vision loss and can still walk independently.
Hong Kong, Hong KongAges 55–80 - NCT06000111Recruiting
Face down positioning after macular hole surgery
This trial compares different lengths of face down positioning after surgery for a macular hole. It aims to find the best duration to help the hole heal while being easier for patients.
Stoney Creek, OntarioAges 18 years+ - NCT06016712Recruiting
Labor's effect on eye pressure in first-time mothers
This study measures how eye pressure changes during labor in healthy first-time mothers. It may help understand how childbirth affects eye health.
PragueAges 18 years+ - NCT06017362RecruitingPhase 4
Insulin drops for dry eye in glaucoma patients
This study tests whether insulin eye drops can safely help dry eye in people who also use eye drops for glaucoma. It may offer a new option if you have both conditions and your eye pressure is stable.
Madrid, MadridAges 18 years+ - NCT06022029RecruitingPhase 1
Study of injected ONM-501 alone or with cemiplimab for advanced cancers
This trial tests an injected study drug (ONM-501) alone or with another drug (cemiplimab) for people with advanced solid tumors or lymphomas that haven't responded to other treatments. It aims to find a safe dose and see if the combination helps shrink or control the cancer.
Los Angeles, CaliforniaAges 18 years+ - NCT06023550Recruiting
Complicated Ear, Nose, and Throat Infections Study
This study looks at patients with complicated infections of the ear, nose, throat, or neck that are treated at a specific hospital in Slovenia. The goal is to learn more about these infections and how they are managed.
Ljubljana, LjubljanaAges Any age - NCT06033703RecruitingPhase 1/Phase 2
Netarsudil Drops After Retinal Detachment Surgery
This study tests whether netarsudil eye drops can prevent vision-threatening scar tissue (proliferative vitreoretinopathy) after retinal detachment repair. If you are having surgery for a retinal detachment, these drops may reduce the risk of complications.
Boston, MassachusettsAges 18 years+ - NCT06034327Recruiting
Testing a new spectacle lens for slowing myopia in kids 6–8
This study tests a special spectacle lens designed to slow the progression of nearsightedness (myopia) in children aged 6 to 8. It may be a good option for kids who are mildly to moderately nearsighted and haven't used other myopia control treatments.
Oakland, CaliforniaAges 6–8 - NCT06046118Recruiting
Light therapy for dry age-related macular degeneration
This trial tests whether a special light treatment (photobiomodulation) can help people with dry age-related macular degeneration (AMD). It is designed for those with early to moderate dry AMD who still have fairly good vision.
ParisAges 50 years+ - NCT06047717Recruiting
Virtual reality navigation study for stroke survivors
This study uses virtual reality to understand how vision loss from a stroke affects navigation. You may help researchers learn more by wearing a VR headset and doing simple tasks.
Rochester, New YorkAges 21–75 - NCT06048380RecruitingPhase 3
Ripasudil drops for FED patients having cataract surgery
This trial tests if ripasudil eye drops can help people with Fuchs' endothelial dystrophy (FED) during and after cataract surgery. It aims to see if the drops protect the eye's inner layer and improve recovery.
Singapore, SingaporeAges 50–100 - NCT06049459Recruiting
Virtual Reality Games for Lazy Eye in Kids
This study tests if playing virtual reality games can help improve vision in children with lazy eye (amblyopia). It may be an option for kids who haven't fully improved with glasses or patching.
Columbus, OhioAges 5–17 - NCT06053554Recruiting
Comparing two cataract surgery methods for pseudoexfoliation
This study compares two different surgical methods for placing a new artificial lens (IOL) during cataract surgery in people with pseudoexfoliation syndrome. It aims to find which method works best for these patients.
ViennaAges 60–100 - NCT06054542Recruiting
Digital eye strain questionnaire Turkish study
This study tests a Turkish version of a questionnaire about digital eye strain. It is for people aged 18–65 who use digital devices for at least two hours a day.
AntalyaAges 18–65 - NCT06056921RecruitingPhase 1
CAR T-cell therapy for hard-to-treat autoimmune diseases
This trial tests a new treatment using your own immune cells (CAR T-cells) targeting a protein called CD19 to control severe autoimmune diseases like lupus, Sjogren's, scleroderma, dermatomyositis, or vasculitis. The goal is to see if it's safe and can improve symptoms when other treatments haven't worked.
Taiyuan, ShanxiAges 18 years+ - NCT06057051Recruiting
Stent implant for mild to moderate open-angle glaucoma
This trial studies a tiny implant called iStent Infinite that helps drain fluid from the eye to lower pressure in people with mild to moderate open-angle glaucoma. It may offer a new way to manage the condition.
Cincinnati, OhioAges 35 years+ - NCT06059521Recruiting
Comparing a mobile vision test to standard eye exams
This trial tests a new way to measure your eyeglass prescription using a mobile device, compared with a traditional method called retinoscopy. It may help you get a quick and accurate vision check without needing special equipment.
Beijing, Beijing MunicipalityAges 10–46
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,816 recruiting ophthalmology studies from the U.S. registry right now, out of 2,919 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.