Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,762 recruiting studies in this area right now.
By phase
- Not applicable1,201
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 286
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- National Taiwan University Hospital15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona69
- Florida43
- Maryland39
- Texas37
- New York36
- Massachusetts35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,762 total
- NCT07269665RecruitingEarly Phase 1
Gene therapy trial for children with BBS1 retinal degeneration
This early-phase trial tests a gene therapy called AXV-101 for children with vision loss caused by BBS1 genetic mutations. The goal is to see if it can help slow or stop retinal damage.
LondonAges 4–17 - NCT06805474Recruiting
Study of a vision test for Stargardt and geographic atrophy
This study tests a new way to measure vision, called MLSDT, in people with normal sight or vision loss from Stargardt disease or geographic atrophy (a type of advanced age-related macular degeneration). Results will help doctors better understand how well patients can see.
Dallas, TexasAges 18 years+ - NCT07276217Recruiting
Cataract surgery lens registry study
This trial is a registry for people having cataract surgery in both eyes. It collects information on different types of artificial lenses used to improve vision, and follows up to see how well they work.
WarsawAges 18 years+ - NCT07277257RecruitingPhase 4
New dry eye treatment for people with Sjögren's syndrome
This study tests a new treatment for dry eye disease caused by Sjögren's syndrome. It may help people who still have dry eye symptoms even when using artificial tears.
Venice, FloridaAges 18 years+ - NCT07272005Recruiting
Improving control of intermittent exotropia
This trial tests ways to improve control of intermittent exotropia, a type of eye misalignment that comes and goes, without surgery for at least 6 months.
Dallas, TexasAges 4–10 - NCT07275021Recruiting
Brain Injury & Vision Screening in Newborns
This study looks for early signs of vision problems in babies who had brain injuries around the time of birth. It aims to help doctors better identify and predict these issues.
Boston, MassachusettsAges 7 months–10 months - NCT07276386RecruitingPhase 2
Combination therapy for metastatic uveal melanoma
This trial tests a two-part treatment for uveal melanoma that has spread to the liver. First, you get a liver-directed chemotherapy (melphalan) through a special procedure called PHP, then you receive an immunotherapy drug (tebentafusp) that helps your immune system attack the cancer.
Tampa, FloridaAges 18 years+ - NCT07273747Recruiting
Kelulut honey for eye allergy and dry eye
This study tests if Kelulut honey eye drops can help people with both allergic conjunctivitis (eye allergies) and dry eye symptoms. If you have been diagnosed with eye allergies and still have bothersome symptoms despite treatment, this trial may offer a natural option to explore.
Kota Bharu, KelantanAges 18–40 - NCT07276087Recruiting
Physical and Mental Health in Takayasu Arteritis and Behçet's Disease
This study compares physical and mental health in people with Takayasu arteritis or Behçet's disease to healthy volunteers. It aims to better understand how these conditions affect day-to-day life and well-being.
Denizli, DenizliAges 18 years+ - NCT07270133Recruiting
Diabetes eye health observation study
This study observes how diabetes affects vision over time in people with diabetes. It helps doctors better understand eye health without any treatment or intervention.
Augusta, GeorgiaAges 18 years+ - NCT07278843Recruiting
Understanding vision loss in Usher syndrome type 1B
This study follows people with Usher syndrome type 1B over time to learn how vision loss progresses. It also tests new ways to measure functional vision, which may help design future treatments.
Paris, Île-de-France RegionAges 3–75 - NCT06892353Recruiting
AI eye screening for diabetic retinopathy
This trial tests a new AI-powered, do-it-yourself screening system for diabetic retinopathy. It may help find early signs of eye disease in people who haven't had an eye exam in the past year.
Hong KongAges 18 years+ - NCT06893913Recruiting
Fasting plus exercise for dry eyes in psoriasis
This study tests whether adding a simple exercise (pyramidal exercise) to intermittent fasting can help reduce dry eyes in people who have psoriasis, prediabetes, and mild obesity. It aims to see if lifestyle changes can improve eye moisture.
Giza, DokkiAges 45–55 - NCT07260097Recruiting
Eye imaging study after retinal detachment surgery
This study looks at how blood flow changes in the eye after a type of retinal detachment surgery called scleral buckling. It uses imaging to check the eye's blood vessels, and may help doctors understand recovery better.
SingaporeAges 21 years+ - NCT07262476RecruitingPhase 3
Extension study of MHB018A for thyroid eye disease
This study tests a longer-term use of MHB018A for people with thyroid eye disease who did not fully respond to treatment in a previous study. It aims to see if further treatment can help improve eye bulging and other symptoms.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07259928RecruitingPhase 2
Testing ANXV for diabetic retinopathy or retinal vein occlusion
This trial tests a new drug called ANXV (Annexin A5) to see if it is safe and can help people with diabetic retinopathy or a recent retinal vein occlusion. The goal is to reduce eye damage and improve vision.
LondonAges 18 years+ - NCT07265258RecruitingPhase 4
Teprotumumab for active thyroid eye disease
This study tests a drug called teprotumumab for people with active thyroid eye disease. It is designed to help reduce eye bulging and other symptoms, and may be an option if you have not had strong treatments before.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07266584Recruiting
Retinal implant for central vision loss in inherited eye disease
This trial tests a new implant (PRIMA) placed under the retina to help restore central vision in people with inherited retinal degeneration. If you have very poor central vision and a large enough area of retinal damage, this device may help you see better.
Sydney, New South WalesAges 18 years+ - NCT07261345RecruitingEarly Phase 1
CAR-T cell therapy for hard-to-treat Graves' disease
This early-phase trial tests whether specially engineered immune cells (called CAR-T) can treat Graves' disease that hasn't responded to standard medication. It's for people with active, hard-to-control Graves' who have the TRAb antibody.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07265024Enrolling by invitation
Exercise study for university students with vision loss
This study tests whether a traditional exercise program can improve health and well-being in university students who are visually impaired. It may help you if you can walk independently and don't have serious health issues.
Changchun, JilinAges 18 years+ - NCT07269106RecruitingPhase 4
Testing anrikefon for pain relief after eye surgery
This trial tests a new painkiller called anrikefon for people having eye surgery under general anesthesia. It aims to see if it's safe and effective for controlling pain after the procedure.
Guangzhou, GuangdongAges 18–70 - NCT07262125Enrolling by invitation
Carbon dioxide pressure and eye nerve sheath in kidney surgery
This study looks at how the carbon dioxide gas used during keyhole kidney cancer surgery affects the pressure behind your eye. The goal is to see if changes in gas pressure influence the nerve sheath that surrounds the optic nerve.
Istanbul, AtaşehirAges 31–69 - NCT07260695RecruitingPhase 4
Odyssey Lens Study for Post-LASIK Cataract Patients
This trial tests a new type of lens implant (Odyssey IOL) for people who have had LASIK surgery and now have cataracts. It aims to see how well the lens works after cataract surgery in both eyes.
Venice, FloridaAges 50 years+ - NCT07264283Enrolling by invitationPhase 2
Testing LM11A-31 for progressive supranuclear palsy
This trial tests a drug called LM11A-31 to see if it can help people with progressive supranuclear palsy (PSP), a rare brain condition. You may join if you have had symptoms for 5 years or less, can walk with minimal help, and have good thinking abilities.
San Francisco, CaliforniaAges 41–86
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,762 recruiting ophthalmology studies from the U.S. registry right now, out of 2,751 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.