Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,762 recruiting studies in this area right now.
By phase
- Not applicable1,201
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 286
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- National Taiwan University Hospital15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona69
- Florida43
- Maryland39
- Texas37
- New York36
- Massachusetts35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,762 total
- NCT07268599Enrolling by invitation
Acoltremon for moderate-to-severe dry eye relief
This study tests a new eye drop called Acoltremon to see if it can relieve symptoms of moderate-to-severe dry eye disease. It may be a good option if you have had dry eye for at least 6 months and use artificial tears.
Encino, CaliforniaAges 18–60 - NCT07265388Recruiting
Testing a scoring system for Fuchs dystrophy and cataract surgery
This study tests a scoring system to predict how well people with Fuchs dystrophy do after cataract surgery. It may help doctors plan better treatment for your cornea and lens.
Madrid, MadridAges 40 years+ - NCT07260695RecruitingPhase 4
Odyssey Lens Study for Post-LASIK Cataract Patients
This trial tests a new type of lens implant (Odyssey IOL) for people who have had LASIK surgery and now have cataracts. It aims to see how well the lens works after cataract surgery in both eyes.
Venice, FloridaAges 50 years+ - NCT06899360Recruiting
Age-related macular degeneration progression study
This study tracks how age-related macular degeneration (AMD) progresses over time and looks at factors that might affect your vision and quality of life. By participating, you'll help researchers understand more about AMD and what might predict better or worse outcomes.
Udine, UDAges 50–120 - NCT06291935RecruitingPhase 1
Gene therapy trial for retinitis pigmentosa with CNGA1 mutation
This trial tests a new gene therapy called VG901, given as an injection into the eye, for people with retinitis pigmentosa caused by a specific genetic change in the CNGA1 gene. The goal is to see if it is safe and tolerable.
TübingenAges 18 years+ - NCT06899529Recruiting
Bevacizumab after eye surgery for diabetic retinopathy
This trial tests whether giving bevacizumab (a medicine that slows abnormal blood vessel growth) right after vitrectomy (a surgery to remove blood or scar tissue from the eye) can help people with advanced diabetic eye disease. The goal is to improve vision and reduce the need for more treatments.
Querétaro City, QuerétaroAges 18 years+ - NCT02964637Recruiting
Tests to help diagnose frontotemporal dementia
This study looks at testing (including brain scans) to figure out what type of frontotemporal dementia or related language/speech condition a person has. It may help by making diagnoses more accurate, which can guide better care.
Toronto, OntarioAges 18–90 - NCT07250139Recruiting
Comparing Ziplyft vs. eyelid surgery for upper eyelid rejuvenation
This study compares a new non-surgical treatment called Ziplyft with traditional eyelid surgery (blepharoplasty) to reduce extra skin on the upper eyelids. It may be a good option for people who want to refresh their eyes without a full surgery.
Oxford, North CarolinaAges 35 years+ - NCT07258212Recruiting
Safety and normal vision data study with Neos device
This study is testing a device called Neos to gather safety information and normal vision data. It includes both healthy volunteers and people with eye or brain conditions, helping researchers understand how vision and eye movements work.
Bern, Canton of BernAges 3 years+ - NCT07257341Recruiting
Normal eye alignment and vision range study for adults
This study measures the normal range of how well eyes work together to see a single image. It may help understand healthy vision in adults of Asian descent.
Singapore, SingaporeAges 21–59 - NCT07255859Recruiting
Home monitoring for wet AMD using a webcam
This study tests a home monitoring system using a webcam to check for signs of wet AMD returning. It may help you manage your condition between doctor visits and catch problems early.
SingaporeAges 50–99 - NCT07257172Recruiting
New way to fix a shifted lens using iris hooks
This trial tests a special technique to reposition and secure the eye's lens without stitches. It uses small hooks on the iris to hold the lens in place, which may help people with a partially dislocated lens avoid more complex surgery.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT04658238Recruiting
Dry eye study of the eye microbiome and immune system
This trial looks at how changes in the eye’s normal germs (microbiome) and the immune response may relate to dry eye. It may help researchers better understand what drives symptoms and how to improve care.
BernAges 18 years+ - NCT07249216Recruiting
Studying eye fluid to improve treatment for wet age-related macular degeneration
This study looks at whether certain proteins or molecules in the jelly-like fluid inside the eye can predict why some people with wet age-related macular degeneration do not respond well to standard anti-VEGF injections. By studying these signals, researchers hope to improve future treatment and better tailor care to individual patients.
SingaporeAges 50 years+ - NCT07245082Recruiting
Type 2 diabetes patient study
This study looks at people with type 2 diabetes to understand their health. If you join, you'll have simple measurements taken like height, weight, and grip strength.
Taipei, Zhongzheng DistAges 18 years+ - NCT07244276Recruiting
Comparing stitches for pterygium surgery
This trial tests a new way of stitching the eye after pterygium removal to see if it works better than the usual method. If you have a pterygium that needs surgery, this study might be for you.
Tianjin, Tianjin MunicipalityAges 30–70 - NCT07245017RecruitingEarly Phase 1
Testing JN002 drops for dry eye disease
This trial tests whether a new eye drop, JN002, can help people with dry eye disease. It checks if the drops improve symptoms and eye health over time.
ShanghaiAges 18 years+ - NCT07243665Recruiting
Glaucoma screening with AI for diabetes patients
This trial tests whether artificial intelligence can help find glaucoma early in people with diabetes who already get regular eye checks for diabetic eye disease. It may help catch glaucoma sooner without extra tests.
Singapore, SingaporeAges 21 years+ - NCT07244614Recruiting
Study of ustekinumab or apremilast for Behçet's disease symptoms
This study tests if ustekinumab or apremilast can help control Behçet's disease symptoms like mouth and genital ulcers, skin sores, and joint pain. It may be an option if standard treatments haven't worked well.
BordeauxAges 18 years+ - NCT07249060Recruiting
Interferon levels in cancer and autoimmune disease patients
This study looks at a protein called interferon in the blood of people with cancer who are starting immunotherapy, and people with certain autoimmune diseases (such as lupus, Sjögren's syndrome, scleroderma, or inflammatory myopathy). The goal is to compare interferon patterns and better understand immune responses.
Pamplona, NavarreAges 18 years+ - NCT06794008RecruitingPhase 2
CAR-T cell therapy for hard-to-treat autoimmune diseases
This trial tests a new treatment using your own immune cells (called CAR-T cells) designed to target and attack cells that cause autoimmune diseases. It is for people with lupus, Sjögren's syndrome, inflammatory myopathy, scleroderma, Behcet's disease, ANCA-associated vasculitis, IgG4-related disease, antiphospholipid syndrome, or thrombotic thrombocytopenic purpura who have not improved with standard therapies.
Beijing, Beijing MunicipalityAges 18–65 - NCT06523751Recruiting
Predicting success of a glaucoma surgery with a quick test
This study tests a new quick procedure called trabeculopuncture to see if it can predict whether a more involved glaucoma surgery (ab interno trabeculectomy) will work for you. If you have a specific type of glaucoma, high eye pressure despite drops, and need cataract surgery, this trial might help lower your pressure and reduce medications.
Würzburg, BavariaAges 18 years+ - NCT07236671Recruiting
Study of enlarged eye blood vessel changes
This study looks at how certain enlarged blood vessels in the back of the eye change over time. By taking special images, researchers hope to learn more about these vessels. It might help if you have been told you have pachyvessels.
Hong KongAges 45 years+ - NCT07235085RecruitingPhase 3
Study of OTX-TKI implant for moderate to severe NPDR
This study tests an eye implant (OTX-TKI) that slowly releases a medicine to slow or stop worsening of non-proliferative diabetic retinopathy (NPDR) — an early form of diabetic eye disease. It's for people with moderately severe to severe NPDR who haven't had significant treatments like laser or injections in that eye.
Hagerstown, MarylandAges 18 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,762 recruiting ophthalmology studies from the U.S. registry right now, out of 2,751 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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- Pain
- Injuries & trauma
- Mouth & dental
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.