Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,816 recruiting studies in this area right now.
By phase
- Not applicable1,253
- Phase 3130
- Phase 2121
- Phase 1120
- Phase 491
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract90
- Myopia89
- Diabetic Retinopathy52
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Macular Degeneration22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California141
- Arizona66
- Texas41
- Maryland39
- New York34
- Massachusetts33
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania21
Recruiting studies1,816 total
- NCT06541574RecruitingPhase 2
Preventing scar tissue after retinal detachment surgery
This trial tests if injecting a medication called methotrexate into the eye during retinal detachment surgery can prevent scar tissue from forming. Scar tissue can sometimes cause the retina to detach again, so this treatment might lower that risk.
Cincinnati, OhioAges 18 years+ - NCT06541626Recruiting
Study of CNS inflammatory demyelinating diseases
This study follows people with certain inflammatory conditions of the brain and spinal cord (like MS, NMOSD, or MOGAD) to learn more about their disease. If you join, you will help researchers understand these conditions better.
Guangzhou, GuangdongAges 18–65 - NCT06543303RecruitingPhase 2
Testing BTV100 for moderate to severe dry eye
This trial tests BTV100, an investigational eye drop, for people with ongoing moderate to severe dry eye disease. It aims to see if the treatment can improve dryness and discomfort.
Doncaster East, VictoriaAges 18 years+ - NCT06543667RecruitingPhase 1
Stem cell eye drops for dry eye treatment
This trial tests a new eye drop made from stem cells to see if it can help relieve dry eye symptoms. It is for people with moderate to severe dry eye who haven't had recent eye surgery or used other eye drops.
TehranAges 18–70 - NCT06544447RecruitingPhase 1/Phase 2
Ear nerve stimulation for dry eye with blocked oil glands
This trial tests a gentle nerve stimulation device placed on the ear to see if it can improve dry eye symptoms caused by blocked oil glands. It may offer a new, drug-free option for relief.
Beijing, Beijing MunicipalityAges 18–65 - NCT06548607RecruitingEarly Phase 1
CAR-T therapy for autoimmune diseases
This early-phase trial tests a new CAR-T cell therapy that targets CD19 or both CD19 and BCMA to treat several autoimmune diseases like lupus, scleroderma, and vasculitis. It aims to calm the overactive immune system with a single infusion of your own engineered cells.
Bengbu, AnhuiAges 18–70 - NCT06549010Recruiting
Virtual reality vision test for healthy eyes and glaucoma
This study tests a new virtual reality device to measure your field of vision (how well you see at the edges). It will compare the VR test to the standard bowl test. If you have healthy eyes or glaucoma, you may be able to join.
Chicago, IllinoisAges 25–70 - NCT06549023Recruiting
One session vs multiple sessions of laser for diabetic eye disease
This study compares having laser treatment for diabetic eye disease in one session versus spreading it over multiple sessions. The goal is to find out if one approach is better for your eyes and easier for you.
MölndalAges 18 years+ - NCT06550674Recruiting
Genetic study for uveal melanoma risk
This study looks for new inherited genes linked to uveal melanoma (an eye cancer). If you have this cancer and don't already have a known genetic cause, you may be able to help find new genes that affect cancer risk.
Clermont-Ferrand, Puy-de-DômeAges 18 years+ - NCT06555289Recruiting
New lens implant after prior laser vision correction
This study tests a new type of artificial lens (Clareon PanOptix Pro) for people who have had LASIK or PRK in the past and now need cataract surgery. It aims to see how well the lens works for these patients, potentially improving vision after surgery.
Albuquerque, New MexicoAges 45 years+ - NCT06557460RecruitingPhase 2
Cell implant for advanced dry age-related macular degeneration
This trial tests a patch of retinal cells implanted under the retina to see if it can slow or stop vision loss from advanced dry AMD (geographic atrophy). It may help people whose central vision is already affected.
Beverly Hills, CaliforniaAges 55–90 - NCT06563414Recruiting
A study tracking eye scrapes in people with DEB
This study follows people with dystrophic epidermolysis bullosa (DEB) who get scrapes on the surface of their eye (corneal abrasions). It collects information to better understand how often and how severely these eye injuries happen.
Pittsburgh, PennsylvaniaAges 6 months+ - NCT06565091Recruiting
Testing a new all-in-one eye measurement device
This study tests a new all-in-one device that measures several aspects of your eyes during a routine check-up. You just sit in front of it, no extra procedures. It's for both adults and children who already have an eye appointment.
RennesAges 4 years+ - NCT06569758RecruitingPhase 1
A study of GenSci098 for active thyroid eye disease
This study tests a new medication called GenSci098 for people with active thyroid eye disease. It aims to reduce eye symptoms like redness, swelling, and bulging, and improve quality of life.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06570226Recruiting
Tea and health in college students
This study looks at whether drinking tea can help college students with blood pressure, body shape, and vision. You may participate if you are a healthy college student without certain medical conditions or allergies.
TaipeiAges 15–22 - NCT06577857Recruiting
Long-term follow-up for MIMS eye procedure
This study is checking on people who had a specific eye surgery called MIMS at least two years ago. It aims to see how they are doing over time.
YerevanAges 40–85 - NCT06581406RecruitingPhase 2/Phase 3
RP2 with nivolumab for untreated uveal melanoma
This clinical trial tests a new treatment called RP2 (a virus that attacks cancer cells) combined with nivolumab (an immunotherapy drug) for people with metastatic uveal melanoma who have never had immunotherapy before. It aims to see if this combination can shrink tumors and improve outcomes.
Scottsdale, ArizonaAges Any age - NCT06582472Recruiting
Early eye changes and diabetes trial
This study looks at early damage to the retina (the back of the eye) in people with type 2 diabetes, even before vision problems start. It aims to find new ways to detect and treat diabetic eye disease early.
Milan, Italy/milanAges 40–80 - NCT06587828Recruiting
Looking at immune cells in people with autoimmune disease
This study collects blood, tissue, and other samples from people with autoimmune diseases like Crohn's disease, multiple sclerosis, or lupus. Researchers will study your immune cells (T cells) to learn what they are attacking, which could lead to better treatments in the future.
Orange, CaliforniaAges 18 years+ - NCT06587945RecruitingPhase 4
Nicotinamide riboside for retinal detachment repair
This trial tests if taking a daily supplement called nicotinamide riboside after retinal detachment surgery can help the eye heal better and see more clearly. It is for people who had a specific type of retinal detachment and have already had cataract surgery.
East Melbourne, VictoriaAges 18 years+ - NCT06588764Recruiting
Modified eye surgery for moderate to severe Graves' eye disease
This trial tests a modified orbital decompression surgery to treat moderate-to-severe swelling and bulging of the eyes caused by Graves' disease. It aims to improve eye function and appearance for people whose thyroid condition has been stable for at least 6 months.
Guangzhou, GuangdongAges 18–80 - NCT06590220Recruiting
Predicting treatment needs for moderate to severe thyroid eye disease
This study aims to build a model that helps doctors predict how thyroid eye disease (TAO) will progress, specifically for patients with moderate to severe symptoms. If you have had TAO and meet the activity criteria, your participation could lead to better personalized care.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06591793RecruitingPhase 1/Phase 2
Gene therapy for Usher syndrome type 1B vision loss
This trial tests an experimental gene therapy given as an injection under the retina. It aims to slow or stop vision loss in people with Usher syndrome type 1B, a rare genetic condition that causes both hearing and vision problems.
NaplesAges 18–50 - NCT06593405RecruitingEarly Phase 1
Occupational therapy for eye disease medication management
This trial tests whether occupational therapy can help people with age-related macular degeneration (AMD), diabetic retinopathy (DR), or glaucoma better manage their medications. Participants share their deidentified data to see if therapy improves outcomes.
Worcester, MassachusettsAges 50–100
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,816 recruiting ophthalmology studies from the U.S. registry right now, out of 2,919 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Immune system & allergy
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- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.