Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,762 recruiting studies in this area right now.
By phase
- Not applicable1,201
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 286
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- National Taiwan University Hospital15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona69
- Florida43
- Maryland39
- Texas37
- New York36
- Massachusetts35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,762 total
- NCT07133438RecruitingPhase 4
Vitamin B12 with eye injections for blocked retinal vein
This trial tests if adding mecobalamin (a form of vitamin B12) to standard anti-VEGF eye injections helps people with vision loss caused by a blocked vein in the retina. You must have swelling in the back of the eye and have had no prior treatments for this condition.
ChongqingAges 18–80 - NCT07135167RecruitingPhase 3
Epi-ON corneal crosslinking study for people with Down syndrome
This study tests a special light treatment for cornea problems in people with Down syndrome. It aims to strengthen the front of the eye and may help prevent vision loss.
Atlanta, GeorgiaAges 8 years+ - NCT05397873Recruiting
Biofeedback training to improve vision in hemianopia
This trial tests whether guided “biofeedback” training can help people with hemianopia (a vision field loss) improve how they use their remaining vision. You may be asked to complete vision testing and practice exercises while receiving feedback based on your responses.
Toronto, OntarioAges 18–90 - NCT04910503RecruitingPhase 4
Compare fluocinolone and dexamethasone implants for resistant eye swelling
This trial looks at which long-acting steroid implant works better for diabetic macular swelling that did not improve enough with past treatments. It may help patients by testing a treatment option aimed at improving vision when other eye injections have not worked well.
DijonAges 18 years+ - NCT07118241RecruitingPhase 2
Testing a new eye drop for Sjögren's dry eye
This trial tests a new eye drop made from a natural protein (rhPRG4) to see if it safely and effectively relieves dry eye symptoms in people with Sjögren's syndrome. You'll be randomly assigned to receive the study drop or a placebo (inactive) drop for several weeks.
Sydney, New South WalesAges 18–80 - NCT07118254RecruitingPhase 2
Eye drops for dry eye from graft-versus-host disease
This study tests whether a new eye drop (rhPRG4) can safely reduce dry eye symptoms caused by graft-versus-host disease (GVHD). It compares the active drops to an inactive placebo to see if they provide better relief.
Sydney, New South WalesAges 18–75 - NCT07120178Recruiting
Imaging and outlook for colored eye growths in children
This study looks at how colored growths on the front of the eye (called pigmented tumors) are imaged and how they change over time in children. Researchers want to understand these growths better to improve care.
Saint-EtienneAges Up to 18 years - NCT07119580Recruiting
Glaucoma, eye surface health, and tear proteins
This study looks at how glaucoma and its treatments affect the surface of the eye and proteins in tears. It may help find better ways to manage eye health in people with glaucoma.
HsinchuAges 18 years+ - NCT07117981Recruiting
Study of second-line treatment for thyroid eye disease
This trial looks at how thyroid eye disease (inflammation behind the eyes) changes over time in people who need stronger treatments after steroids haven't worked well enough. It aims to better understand the disease and how different second-line treatments may help.
Paris, parisAges 18 years+ - NCT07124572Recruiting
Building a Better Diagnosis System for Thyroid Eye Disease
This study aims to build a better system for diagnosing and treating thyroid-associated ophthalmopathy (a thyroid eye condition). It may help improve care for people with this disease, and also involves healthy volunteers as a comparison group.
Hangzhou, ZhejiangAges 7–90 - NCT07124910RecruitingPhase 3
Comparing two UV light times for corneal crosslinking
This trial tests two different UV light exposure times (18 minutes vs. 24 minutes) during a corneal crosslinking procedure for people with keratoconus or similar corneal thinning conditions. The goal is to see if the shorter time works as well as the longer one.
Atlanta, GeorgiaAges 8 years+ - NCT07119723Enrolling by invitation
Study on environment and nearsightedness in Uyghur children
This trial looks at how things in the environment might affect nearsightedness (myopia) in Uyghur children living in remote parts of China. If your child is between 6 and 15 and has no other eye problems, this study could help understand what causes myopia and how to prevent it.
TianjinAges 6–15 - NCT06964269RecruitingPhase 4
Acthar Gel for dry eye and autoimmune disease
This trial tests a new injectable medicine, Acthar Gel, for moderate to severe dry eye and eye pain linked to autoimmune disease. It aims to see if the drug can relieve these symptoms safely.
Nashville, TennesseeAges 18–85 - NCT07113262RecruitingPhase 3
Study of IBI311 for people with inactive thyroid eye disease
This trial tests a new medication called IBI311 for people whose thyroid eye disease is no longer active but still causes bulging eyes. It aims to see if the drug can reduce eye bulging safely.
Shenyang, LiaoningAges 18–80 - NCT07109609Enrolling by invitationPhase 2
Testing Menthol on Skin to Increase Tears
This study tests whether applying menthol to the skin on your cheeks can help increase tear production. If you have dry eyes but are not under an eye doctor's care for it, this trial might be a fit.
Toronto, OntarioAges 18 years+ - NCT07113210RecruitingPhase 4
Quality of life with Qlosi eye drops for presbyopia
This trial tests whether a new prescription eye drop called Qlosi improves the quality of life for people with presbyopia (age-related trouble seeing up close). You will use the drops regularly and answer questions about your vision and daily activities.
Medina, MinnesotaAges 45–64 - NCT07110493Recruiting
Visual snow and TMS study
This study uses a technique called Transcranial Magnetic Stimulation (TMS), which uses magnetic pulses to gently stimulate parts of your brain, to explore how people with visual snow syndrome, color blindness, or normal vision perceive light patterns. This may help understand why visual snow happens and how to treat it.
MoscowAges 18–65 - NCT03803852Recruiting
Testing different toric lens types during cataract surgery
This study compares different types of artificial lens implants (including toric lenses that correct astigmatism) during cataract surgery. It may help find which lens options work best for your vision and astigmatism correction.
Vienna, State of ViennaAges 45–95 - NCT07105358Recruiting
Vision recovery study after brain damage
This study tests whether the brain can improve vision after damage caused by stroke, tumor, or injury. It may help people with vision loss from a brain lesion find new ways to see better.
Washington D.C., District of ColumbiaAges 18 years+ - NCT07096232Enrolling by invitation
AI vs doctor for eye surgery and keratoconus diagnosis
This study compares an AI system to a specialist eye doctor to see which is better at diagnosing vision problems like nearsightedness, farsightedness, astigmatism, and keratoconus. Your existing medical records will be used to see how well the AI performs.
Cairo, MaadiAges Any age - NCT07100990RecruitingPhase 3
Early versus rescue plasma exchange for optic neuritis or transverse myelitis
This study tests whether starting plasma exchange early (right after steroids) is better than waiting to see if steroids are enough for people with severe optic neuritis or transverse myelitis. It may help preserve vision or movement by stopping inflammation sooner.
Birmingham, AlabamaAges 18 years+ - NCT07095907Recruiting
Eye surgery for scar tissue on the retina
This study is for people who have a stage III or IV epiretinal membrane, a thin layer of scar tissue on the retina that can cause blurry or distorted central vision. It tests a surgical approach called controlled macular detachment to see how it helps visual symptoms and recovery.
Mexico CityAges 18 years+ - NCT07095894RecruitingPhase 3
Glasses or eye drops for slowing nearsightedness in kids
This study tests whether special glasses or low-dose atropine eye drops can slow down worsening nearsightedness in children. It compares four groups: glasses alone, eye drops alone, both together, or a placebo (no active treatment).
Birmingham, AlabamaAges 5–11 - NCT07096622Recruiting
Visual training for kids after lens surgery
This study tests whether special visual and perceptual training exercises can help improve eyesight in children who have had surgery for a naturally dislocated lens (congenital ectopia lentis). It is for kids aged 4–12 whose vision is still below normal after their second eye surgery.
Guangzhou, GuangdongAges 4–12
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,762 recruiting ophthalmology studies from the U.S. registry right now, out of 2,751 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.