Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,760 recruiting studies in this area right now.
By phase
- Not applicable1,199
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 286
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- National Taiwan University Hospital15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona69
- Florida43
- Maryland39
- Texas37
- Massachusetts35
- New York35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,760 total
- NCT07051720Recruiting
Comparing advanced lenses for cataract surgery
This study compares five different advanced lenses (that give a range of focus) with a standard single-focus lens for cataract surgery. It aims to see which lens provides the best overall vision.
Ahaus, North Rhine-WestphaliaAges 22–85 - NCT07053631Recruiting
New method to measure skull pressure using an eye vein
This study tests a new way to measure pressure inside the skull by using a small vein near your eye. It is for people who are already having a routine test to check fluid pressure around the brain.
Freiburg im BreisgauAges 18–95 - NCT06970236Recruiting
Strength training for eye melanoma survivors
This trial tests whether a high intensity resistance (strength) training program can help people who have been treated for choroidal melanoma (an eye cancer) with plaque brachytherapy. The goal is to improve muscle strength and overall health after cancer treatment.
Valencia, SpainAges 18 years+ - NCT06992011Recruiting
Comparing SMILE vs SMILE Xtra for nearsightedness
This study compares two types of laser eye surgery (SMILE and SMILE Xtra) to see which works better for treating nearsightedness. The goal is to help you see clearly without glasses or contacts.
Shanghai, Shanghai MunicipalityAges 18–50 - NCT07041099RecruitingPhase 1
Study of CLN-978 for Sjögren's disease
This trial tests an experimental drug called CLN-978, given as a shot under the skin, that helps your immune system target and destroy disease-causing B cells. It's for people with moderate to severe Sjögren's disease who haven't had success with other treatments.
Orlando, FloridaAges 18 years+ - NCT07036510RecruitingPhase 1/Phase 2
Safety and effectiveness of a timolol eye implant for glaucoma patients having cataract surgery
This trial tests a sustained-release implant that delivers timolol, a medicine to lower eye pressure, for people with glaucoma or high eye pressure who are also having cataract surgery. The implant is placed during surgery and may provide long-term pressure control without daily eye drops.
Panama CityAges 40 years+ - NCT06982807Recruiting
SMILE laser for stable nearsightedness
This study tests a new laser correction method called SMILE 4.0-VISULYZE to treat nearsightedness and other refractive errors. It may help people who are tired of glasses or contact lenses and want a quick, low-pain vision fix.
Nantong, JiangsuAges 18–40 - NCT07036575Recruiting
Easy-to-Read Content Study for Kids with Learning Challenges
This study tests if easy-to-read materials help children with intellectual disabilities understand health information better. It may benefit kids who have trouble with regular reading materials.
TaipeiAges 3–17 - NCT07040306Recruiting
Follow-up study on drug therapy for Graves' disease
This study looks at how well medication works for people with Graves' disease in China. It may help doctors understand the best treatment options for both new cases and relapses.
Shenyang, LiaoningAges 18 years+ - NCT07038967Recruiting
Cataract surgery and diabetic macular edema progression
This trial studies how diabetic macular edema (swelling in the center of the retina) might change after cataract surgery. It may help doctors understand if surgery is safe for people with this condition.
CairoAges 18 years+ - NCT06992622Recruiting
Youth spine and vision health study
This study is following a group of young people with scoliosis to better understand how their spine and vision change over time. It may help you learn more about your condition and contribute to future care.
Wenzhou, ZhejiangAges 6–17 - NCT01793168Recruiting
Rare disease registry and history study
This study keeps a registry (a structured list) of people with rare diseases and may also track how the condition changes over time. It can help researchers better understand rare illnesses and find gaps in care, which may improve future treatments.
Sioux Falls, South DakotaAges Any age - NCT07029945RecruitingPhase 1/Phase 2
Oral BRX011 for advanced dry age-related macular degeneration
This study tests an oral medication called BRX011 taken once daily for geographic atrophy, a progressive form of advanced dry age-related macular degeneration. The goal is to see if it is safe and can help slow vision loss.
Gilbert, ArizonaAges 55 years+ - NCT07028827RecruitingPhase 3
Atropine eye drops for nearsightedness in kids and teens
This trial tests whether atropine eye drops can slow down worsening nearsightedness (myopia) in children and teenagers. It may help keep their eyesight from getting worse over time.
TiranaAges 3–17 - NCT07024693RecruitingPhase 2
Study of DT-168 for corneal transplant patients with Fuchs dystrophy
This trial tests an investigational eye drop (DT-168) in people with Fuchs endothelial corneal dystrophy who are already scheduled for a corneal transplant. The goal is to see if DT-168 can improve outcomes or delay the need for surgery.
Indianapolis, IndianaAges 30 years+ - NCT06995313Recruiting
Biofeedback training for hemianopia
This trial tests a biofeedback training program for people with hemianopia (vision loss on one side) that started more than 6 months ago. The training uses visual and sound cues to help you make better use of your remaining vision.
Toronto, OntarioAges 18–90 - NCT07030153Recruiting
How genes may affect nearsightedness in children
This study looks at how genes may be linked to nearsightedness (myopia) in children. It involves a simple genetic test to help understand why some kids become nearsighted.
BeijingAges 6–18 - NCT07024719Recruiting
4D microscope OCT during eye surgery study
This trial tests a new microscope that takes 3D images of the eye during surgery. It may help doctors see eye details better while operating.
Durham, North CarolinaAges 18 years+ - NCT07027098Recruiting
Liquid silicone during eye surgery for retinal detachment
This trial tests whether using a liquid called perfluorocarbon (PFCL) during surgery helps the retina heal better in people with a specific type of retinal detachment. The goal is to see if it reduces damage to blood vessels in the eye.
Norwich, NorfolkAges 18 years+ - NCT07025707Recruiting
Comparing two ways to measure lens position after cataract surgery
This trial compares two methods for calculating how much an artificial lens tilts or shifts after cataract surgery. It aims to find which method gives more accurate measurements.
Vienna, State of ViennaAges 21 years+ - NCT07016750RecruitingPhase 3
Study of KB803 eye drops for eye scrapes in DEB
This study tests an experimental eye drop (KB803) to see if it can reduce painful scrapes on the surface of the eye in people with dystrophic epidermolysis bullosa. You would be randomly assigned to receive either the study drops or a placebo (an inactive drop) for several months.
Rancho Santa Margarita, CaliforniaAges 6 months+ - NCT07017907Recruiting
AI tool for detecting thyrotoxic states
This study tests an artificial intelligence tool designed to help detect overactive thyroid conditions (thyrotoxicosis). It may be an option for people with Graves' disease, whether newly diagnosed or currently in treatment.
San Francisco, CaliforniaAges 22 years+ - NCT07018323RecruitingPhase 2
Study of IMVT-1402 for Graves' disease
This trial tests an investigational drug called IMVT-1402 for people with Graves' disease whose thyroid is still overactive even while taking standard antithyroid medication. The goal is to see if the drug can better control thyroid hormone levels.
Tucson, ArizonaAges 18–75 - NCT07015190RecruitingPhase 3
Darovasertib before surgery for eye melanoma
This trial tests a drug called darovasertib given before standard surgery for primary uveal melanoma (a type of eye cancer that hasn't spread). The goal is to see if the drug can shrink the tumor and improve outcomes.
Scottsdale, ArizonaAges 18 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,760 recruiting ophthalmology studies from the U.S. registry right now, out of 2,756 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.