Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,760 recruiting studies in this area right now.
By phase
- Not applicable1,199
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 286
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- National Taiwan University Hospital15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona69
- Florida43
- Maryland39
- Texas37
- Massachusetts35
- New York35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,760 total
- NCT07015190RecruitingPhase 3
Darovasertib before surgery for eye melanoma
This trial tests a drug called darovasertib given before standard surgery for primary uveal melanoma (a type of eye cancer that hasn't spread). The goal is to see if the drug can shrink the tumor and improve outcomes.
Scottsdale, ArizonaAges 18 years+ - NCT07019896Recruiting
Minimal surgery for epiretinal membrane
This trial tests a minimally invasive surgery for people with an epiretinal membrane, a thin layer of scar tissue on the retina that can blur or distort vision. The goal is to see if a smaller, less invasive approach is safe and effective.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07015034Recruiting
Preventing vision loss in older adults with chronic conditions
This study tests a model to help general practitioners find older patients who may be at risk of vision loss. It aims to spot problems early so treatment can start sooner.
Copenhagen, Capital RegionAges 70 years+ - NCT07022197RecruitingPhase 1/Phase 2
BAFF-R CAR T cells for severe nerve and immune diseases
This trial tests a new treatment using your own immune cells (called BAFF-R CAR T cells) for people with severe nerve and immune diseases that have not improved with standard medicines. These cells are designed to target and destroy certain immune cells that may be causing your illness.
Tianjin, Tianjin MunicipalityAges 18–60 - NCT06997354Recruiting
Parent survey to screen children for vision brain problems
This trial is testing a questionnaire for parents to help spot signs of vision problems in children that come from how the brain processes sight, not from the eyes themselves. It aims to make early detection easier for families and doctors.
Louvain-la-NeuveAges 3 years+ - NCT07006649Recruiting
Study of blood flow in the eye for pseudoxanthoma elasticum
This study looks at blood flow in a layer of the eye called the choriocapillaris in people with pseudoxanthoma elasticum (PXE). It compares these findings with healthy volunteers to understand eye changes before they become severe.
AngersAges 18 years+ - NCT07008001Recruiting
DOT glasses for Chinese children with myopia: extension study
This trial tests whether a special type of glasses (called DOT spectacles) can continue to help control nearsightedness in children. Children who already completed the earlier CATHAY study can join and wear the glasses for another 12 months.
ChangshaAges 8–16 - NCT07009236Recruiting
MINIject S+ for open angle glaucoma
This trial tests a tiny implant called MINIject S+ to lower eye pressure in people with open angle glaucoma that isn't well controlled with eye drops. It may be done alone or with cataract surgery.
Santa Rosa de CopánAges 20 years+ - NCT07007897Enrolling by invitation
Cataract treatment observation study
This study is for people with cataracts who are planning to get treatment. It will observe your eye health and treatment process without giving you any new medicine.
Mesa, ArizonaAges 21 years+ - NCT07005323Recruiting
Treatment for age-related macular degeneration that has not improved with standard therapy
This trial tests a new treatment for people with a specific type of age-related macular degeneration (AMD) that has not improved after standard anti-VEGF injections. The goal is to see if it can stop vision loss and reduce retinal damage.
Nagoya, Aichi-kenAges 18–85 - NCT07003685Enrolling by invitation
Glaucoma drainage device for hard-to-treat glaucoma
This study tests a posterior chamber drainage device for people with glaucoma that is not controlled by eye drops, especially those who have already had cataract surgery. It aims to help lower eye pressure safely and prevent further vision loss.
Ho Chi Minh City, Ho Chi MinhAges 18 years+ - NCT07006428Recruiting
Comparing two types of multifocal lens implants for cataract surgery
This trial compares the Clareon PanOptix lens with another similar multifocal lens to see which provides better vision after cataract surgery. It has two stages: one for people who already had the lenses implanted, and one for those who are planning to have cataract surgery.
Torrance, CaliforniaAges Any age - NCT07004361Recruiting
Ethics of gene therapy for wet AMD
This study explores the ethical questions around using gene therapy for wet age-related macular degeneration (AMD). It is not a treatment trial, but a discussion study for patients whose doctors might consider gene therapy as an option.
Nantes, NantesAges 18 years+ - NCT07003308Recruiting
Comparing two surgical techniques for droopy eyelid correction
This trial compares two surgical methods (anterior vs posterior approach) for fixing a droopy upper eyelid (ptosis) that is caused by a stretched tendon. It will help determine which technique leads to better outcomes.
Móstoles, MadridAges 18 years+ - NCT05439161Recruiting
XEN gel stent compared with trabeculectomy for open-angle glaucoma
This trial compares two glaucoma operations to see which works better at lowering eye pressure and keeping the eye stable. It’s for adults with open-angle glaucoma who are eligible for either surgery and can attend follow-up visits.
SalzburgAges 18 years+ - NCT06996080RecruitingPhase 3
Study of KSI-101 for swelling caused by eye inflammation
This trial tests a new medicine called KSI-101 given as an injection into the eye to treat swelling in the center of the retina caused by inflammation. It may help people whose vision has gotten worse due to this type of swelling.
Phoenix, ArizonaAges 18 years+ - NCT07002398RecruitingPhase 1/Phase 2
Gene therapy for Stargardt disease (VG801)
This trial tests a new gene therapy called VG801 for people with Stargardt disease, a genetic condition that causes vision loss. The treatment aims to improve or slow vision loss by delivering a working copy of the ABCA4 gene to the retina.
Shanghai, Shanghai MunicipalityAges 6 years+ - NCT06999733RecruitingPhase 1/Phase 2
Testing KB801 for stage 2 or 3 neurotrophic keratitis
This trial tests whether KB801 can help heal persistent corneal defects better than a placebo. It is for people with neurotrophic keratitis (a condition where the cornea loses sensation) that has not improved with standard care.
Irvine, CaliforniaAges 18 years+ - NCT06997003Recruiting
Study of a new laser for vision correction
This study tests a new laser (called TENEO 317 Model 2) for vision correction. If you're already scheduled for LASIK to fix nearsightedness or farsightedness (with or without astigmatism), you may be eligible. The study checks if this new laser is safe and works well.
Zlín, Czech RepublicAges 18 years+ - NCT07002372Recruiting
Watching a video before your first eye injection
This study tests whether watching a short video before your first eye injection helps you feel more at ease. It is for people who have never had this injection before.
Hangzhou, ZhejiangAges 18 years+ - NCT07000851Recruiting
Brain Imaging Study in Corticobasal Syndrome
This study uses MRI scans to look at the brain in people with Corticobasal Syndrome (CBS). It aims to better understand the condition and may help find better ways to diagnose or treat it.
Rochester, MinnesotaAges 18 years+ - NCT06996353Recruiting
A study of laser eye correction for nearsightedness
This study is collecting health information from people who have undergone a specific laser eye correction procedure (PTK-PRK) for nearsightedness with or without astigmatism. It aims to understand how well the treatment works and how safe it is.
Chandigarh, Punjab HaryanaAges Any age - NCT06993597Recruiting
Eye stiffness study in glaucoma patients using a special camera
This study uses a special camera (Brillouin microscopy) to measure how stiff your cornea is. It compares people with different types of glaucoma to those without glaucoma, helping researchers understand the link between corneal stiffness and eye pressure.
Baltimore, MarylandAges 18 years+ - NCT06997874RecruitingPhase 3
Surgery Comparison for Retinal Detachment Without Prior Cataract Surgery
This trial compares two types of surgery for people with a retinal detachment who still have their natural lens (no prior cataract surgery). One group gets vitrectomy alone; the other gets vitrectomy plus the lens removed at the same time. The goal is to see which approach leads to better outcomes.
AylesburyAges 50 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,760 recruiting ophthalmology studies from the U.S. registry right now, out of 2,756 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.