Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,816 recruiting studies in this area right now.
By phase
- Not applicable1,253
- Phase 3130
- Phase 2121
- Phase 1120
- Phase 491
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract90
- Myopia89
- Diabetic Retinopathy52
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Macular Degeneration22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California141
- Arizona66
- Texas41
- Maryland39
- New York34
- Massachusetts33
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania21
Recruiting studies1,816 total
- NCT06770933RecruitingPhase 2
VX-01 pill for diabetic eye disease study
This trial tests if an oral medication called VX-01 can help people with diabetic eye disease (non-proliferative diabetic retinopathy) that is moderate to severe but not yet at the most advanced stage. It may be an option if you have type 1 or type 2 diabetes and have not had certain prior eye treatments.
Beverly Hills, CaliforniaAges 18 years+ - NCT06771427Recruiting
Exosomes for Sjogren's and Dry Eye
This study looks at tiny particles called exosomes in tears to find new ways to diagnose or treat Sjogren's syndrome and dry eye disease. It may help people with these conditions by learning more about what causes them.
Taipei, TaiwanAges 20–75 - NCT06771908Recruiting
Eye drops to prevent infection after eye surgery
This trial tests if an eye drop called Zamidine® can help prevent infections in people who have a history of repeated eye infections (conjunctivitis) and are about to have eye surgery. The goal is to see if it safely reduces the risk of surgery-related eye infections.
RomeAges 18–90 - NCT06774651Recruiting
Comparing two laser eye surgery methods for vision correction
This trial compares two types of laser eye surgery (CLEAR and SMILE) to see which works better for nearsightedness and astigmatism. If you are eligible, it could help find the best option for your vision.
SingaporeAges 21–50 - NCT06775561Recruiting
Study of hidden DNA causes for rare neuromuscular and epilepsy diseases
This study is for people with a neuromuscular disease or epilepsy whose genetic testing hasn't found a clear answer. It uses advanced techniques to look at parts of the DNA that don't code for proteins, to find hidden causes and help guide future treatments.
BolognaAges Any age - NCT06775808Recruiting
Understanding eye infections through DNA testing
This study looks at eye infections by testing leftover fluid or tissue samples to find all possible germs, including viruses, bacteria, and fungi. It may help doctors better understand what causes different eye infections and improve treatment.
Shanghai, Shanghai MunicipalityAges Any age - NCT06779773Recruiting
Study of avacincaptad pegol (Izervay) for geographic atrophy
This study looks at how avacincaptad pegol (brand name Izervay) works in real-world medical practice for people with geographic atrophy, a form of age-related macular degeneration that causes vision loss. If your doctor has already decided to treat you with this medicine, you may be able to join.
Phoenix, ArizonaAges Any age - NCT06780293RecruitingPhase 2
Laser acupuncture for dry eye and Sjogren's dry eye
This study tests if laser acupuncture can help people with dry eye symptoms, including those with Sjogren's syndrome, which causes dryness in the eyes and mouth. It may be a good fit if you have dry eye or Sjogren's and meet the age and eye test requirements.
Taipei, TaiwanAges 20–75 - NCT06780462RecruitingPhase 3
Steroids with or without blood thinners for Behçet's vein clots
This trial tests whether adding a blood thinner (anticoagulant) to steroid therapy is more effective than steroids alone for treating deep vein thrombosis (a blood clot in a large vein) in people with Behçet's syndrome. It aims to find the best way to prevent future clots and reduce side effects.
BordeauxAges 18 years+ - NCT06780709Recruiting
Wellness program for neuromyelitis optica patients
This trial tests a structured wellness program to improve quality of life for people with neuromyelitis optica (NMOSD). It is designed to be accessible for any level of disability.
New York, New YorkAges 18 years+ - NCT06781970Recruiting
Vitamin C for eye cell protection during cataract surgery
This trial tests whether taking vitamin C before and after cataract surgery can help protect the inner layer of the eye. It is for people aged 60 or older with hard, age-related cataracts who are having phacoemulsification surgery.
Jakarta, DKI JakartaAges 60 years+ - NCT06782997Recruiting
Using a quick eye test to check for diabetes eye damage
This trial tests if a special eye exam (electroretinogram) done by a nurse can find early signs of diabetic retinopathy in people with diabetes who have no known eye problems yet. It aims to make screening easier and more accessible.
ReimsAges 18 years+ - NCT06787482RecruitingPhase 1/Phase 2
Peptide therapy for retinitis pigmentosa
This trial tests a new peptide therapy for people with retinitis pigmentosa (RP), a genetic eye disease that causes vision loss. The goal is to see if the treatment is safe and can help slow or improve vision loss.
CairoAges Any age - NCT06788418Recruiting
Comparing SMILE, ICL, and Alcon Lasers for Nearsightedness
This study compares three different methods to correct nearsightedness: SMILE laser, ICL implantable lenses, and Wavelight Plus laser. The goal is to find which works best for you.
BeijingAges 18–40 - NCT06791226Recruiting
Testing FAPI PET/CT for eye socket tumors
This study tests whether a new type of PET/CT scan (FAPI) can provide better images of tumors in the eye socket than the standard FDG scan. If you have a suspected or newly diagnosed orbital tumor, joining could help doctors see your tumor more clearly.
Beijing, Beijing MunicipalityAges 3–80 - NCT06792422RecruitingPhase 4
Oral semaglutide for open-angle glaucoma
This trial tests if an oral medication called semaglutide can help people with open-angle glaucoma. It aims to see if it can protect the optic nerve and manage eye pressure.
Glostrup MunicipalityAges 45 years+ - NCT06794008RecruitingPhase 2
CAR-T cell therapy for hard-to-treat autoimmune diseases
This trial tests a new treatment using your own immune cells (called CAR-T cells) designed to target and attack cells that cause autoimmune diseases. It is for people with lupus, Sjögren's syndrome, inflammatory myopathy, scleroderma, Behcet's disease, ANCA-associated vasculitis, IgG4-related disease, antiphospholipid syndrome, or thrombotic thrombocytopenic purpura who have not improved with standard therapies.
Beijing, Beijing MunicipalityAges 18–65 - NCT06798766Recruiting
Understanding darker skin tones and vein disease care
This study looks at how people with darker skin tones experience chronic venous insufficiency (a condition that affects blood flow in the legs) and aims to improve how it's diagnosed and treated. It involves two parts: one is sharing your experience through an interview, and the other includes a skin check and photos at the hospital.
London, LondonAges 18 years+ - NCT06801678Recruiting
Comparing two eye measurement devices for cataract surgery
This trial tests two different devices that measure your eyes before cataract surgery to see which one helps doctors choose the best lens implant. The goal is to get your vision as close to perfect as possible after surgery.
Salt Lake City, UtahAges 21 years+ - NCT06805448RecruitingPhase 1/Phase 2
Stem cell treatment for dry mouth in Sjögren's disease
This trial tests if injecting fat-derived stem cells into the salivary glands can help relieve dry mouth in people with Sjögren's disease. It aims to improve saliva flow and reduce discomfort.
CopenhagenAges 18 years+ - NCT06805474Recruiting
Study of a vision test for Stargardt and geographic atrophy
This study tests a new way to measure vision, called MLSDT, in people with normal sight or vision loss from Stargardt disease or geographic atrophy (a type of advanced age-related macular degeneration). Results will help doctors better understand how well patients can see.
Dallas, TexasAges 18 years+ - NCT06805825RecruitingPhase 1
Study of NN3201 for advanced cancers with c-Kit
This trial tests a new drug, NN3201, that targets a protein called c-Kit found on some cancer cells. It may be an option for people with certain advanced solid tumors, including GIST, small cell lung cancer, or other c-Kit-positive cancers, who have already tried standard treatments or cannot take them.
Ann Arbor, MichiganAges 18 years+ - NCT06808633Recruiting
Laser treatment for open-angle glaucoma results
This trial tests how well a laser treatment called selective laser trabeculoplasty works in people with open-angle glaucoma. It looks at results over 12 months to see if it helps lower eye pressure.
Madrid, MadridAges 18 years+ - NCT06812845Recruiting
Eye disease patterns at Sohag University Hospital
This study looks at the different types of eye diseases in people who visit the eye testing unit. It helps doctors understand what conditions are most common so they can improve care.
SohagAges Any age
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,816 recruiting ophthalmology studies from the U.S. registry right now, out of 2,919 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.