Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,760 recruiting studies in this area right now.
By phase
- Not applicable1,199
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 286
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- National Taiwan University Hospital15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona69
- Florida43
- Maryland39
- Texas37
- Massachusetts35
- New York35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,760 total
- NCT06636019Enrolling by invitation
Contact lens for nearsightedness and eye thickness
This trial tests whether a special contact lens can slow down nearsightedness by measuring changes in the thickness of the back layer of your eye. It may help you understand if this lens works for your vision.
AugsburgAges 18 years+ - NCT03648814Recruiting
Bevacizumab eye injections for neovascular glaucoma
This study compares two ways of giving the medicine bevacizumab in the eye: into the front part (intracameral) versus deeper inside (intravitreal). It aims to see which approach better controls neovascular glaucoma and helps vision, especially when surgery (trabeculectomy) is needed.
Hat Yai, Changwat SongkhlaAges 18 years+ - NCT06626516RecruitingPhase 1/Phase 2
Tebentafusp and LDT for metastatic uveal melanoma
This trial tests a combination of two drugs (tebentafusp and a liver-directed treatment called LDT) for people with uveal melanoma that has spread to the liver. The goal is to see if this combination helps shrink tumors and improve outcomes.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06627244RecruitingPhase 2
Study of tebentafusp and radioembolization for uveal melanoma that spread to the liver
This trial tests whether combining a drug called tebentafusp with a procedure called radioembolization can help control uveal melanoma that has spread mainly to the liver. Radioembolization delivers tiny radioactive beads to the liver, and tebentafusp helps your immune system attack the cancer.
Miami, FloridaAges 18 years+ - NCT06631807Enrolling by invitation
How blindness affects sleep, dreams, and spatial skills
This study looks at how the number of years a person has been blind affects their sleep, dreams, and spatial abilities. It may help us understand how the brain adapts when vision is lost, which could lead to better support for people with visual impairments.
GenovaAges 18–85 - NCT06629649Recruiting
AI-based glaucoma screening at health centers
This trial uses an AI tool to screen for glaucoma at community health centers. If you qualify, you will get a free eye check to catch glaucoma early and help researchers improve screening for high-risk groups.
Birmingham, AlabamaAges 18 years+ - NCT06631339Recruiting
Light therapy to prevent and control nearsightedness in kids
This study tests if optimizing daily light exposure can prevent or slow down nearsightedness (myopia) in children. It involves wearing a light-tracking device and spending time in specially lit classrooms.
SingaporeAges 7–10 - NCT06622044Recruiting
Vision therapy vs prism for small-angle eye turn
This trial compares two non-surgical treatments—vision therapy exercises and prism glasses—for people with a recent, constant inward eye turn (esotropia) of a small angle. The goal is to see which approach works better to straighten the eyes.
Shanghai, ChinaAges 10–40 - NCT06619405Recruiting
Eye Function Test for Age-Related Macular Degeneration
This study tests a quick, noninvasive eye test that measures how well you see in the dark, which can be an early sign of dry AMD. Researchers want to see if the test relates to everyday tasks like reading or driving at night.
Durham, North CarolinaAges 50–89 - NCT06620809RecruitingPhase 1
New treatment for neuromyelitis optica flare-ups
This trial tests a new medicine (NouvSoma001) for people with neuromyelitis optica (NMOSD) who are having a flare-up. The goal is to see if the treatment is safe and if it helps reduce symptoms like pain and trouble moving.
Wuhan, HubeiAges 18–65 - NCT06628947RecruitingPhase 2
Testing KIO-301 eye injections for advanced retinitis pigmentosa
This trial tests an eye injection called KIO-301 for people with late-stage retinitis pigmentosa (a genetic eye disease that causes vision loss). The goal is to see if it can improve vision or slow further vision loss.
Sydney, New South WalesAges 18 years+ - NCT06610747Recruiting
Home versus hospital care for diabetic eye swelling
This study tests whether receiving anti-VEGF injections for diabetic macular edema (DME) at home is as safe and effective as getting them in the hospital. You would use a home device to check your vision and eye scans, and a nurse would visit for injections.
Dongguan, GuangdongAges 18 years+ - NCT06612541Recruiting
Eye imaging test for premature babies at risk of ROP
This study tests a new eye imaging device to check for retinopathy of prematurity (ROP), a condition that can affect vision in premature babies. It may help doctors diagnose ROP earlier and more easily at the bedside.
Nashville, TennesseeAges 6 months–8 months - NCT06604104Recruiting
Visual Frailty Study in Older Adults with AMD
This study looks at something called 'visual frailty' in older adults with advanced age-related macular degeneration (AMD). It aims to develop a tool to better understand how vision loss affects daily life and overall health in people aged 60 and over.
Edinburgh, ScotlandAges 60 years+ - NCT06615453Recruiting
Tixel treatment for dry eye disease and periorbital wrinkles
This study tests a device called Tixel that may help reduce wrinkles around the eyes and improve dry eye symptoms. If you have mild to moderate under-eye wrinkles and dry eyes that bother you a lot, this treatment might be an option.
BirminghamAges 18 years+ - NCT06616506Recruiting
AI for cataracts in high myopia
This trial uses artificial intelligence to study cataracts in people with high myopia (very nearsighted). It aims to improve diagnosis and treatment planning for cataract surgery.
Shanghai, Shanghai MunicipalityAges Any age - NCT06596746Recruiting
Tracking markers for neurodegenerative diseases
This study tracks changes in people with Parkinson's disease, other movement disorders, or cognitive decline to find better ways to measure disease progression.
Cassino, FrosinoneAges 10 years+ - NCT06591117Recruiting
Study of a new eye implant for stubborn glaucoma
This study tests a new device to lower eye pressure in people with hard-to-control glaucoma. It is for those who have not had success with other treatments and have open-angle or traumatic glaucoma with high eye pressure.
Colonia Escalón, San SalvadoreAges 22–85 - NCT06596733Recruiting
Testing a new eye ointment for dry eyes (Vit-A-Vision)
This trial tests a medical device eye ointment called Vit-A-Vision for people with dry eye disease. It aims to see if the ointment can improve symptoms and tear film stability over about a month.
CologneAges 18 years+ - NCT06589128Recruiting
Eye product for digital eye strain in children
This study tests an eye product to see if it helps relieve digital eye strain (sore, tired, or dry eyes from screens) in children. It is for kids who have mild to moderate symptoms from using digital devices.
Kepala Batas, Pulau PinangAges 10–11 - NCT06593405RecruitingEarly Phase 1
Occupational therapy for eye disease medication management
This trial tests whether occupational therapy can help people with age-related macular degeneration (AMD), diabetic retinopathy (DR), or glaucoma better manage their medications. Participants share their deidentified data to see if therapy improves outcomes.
Worcester, MassachusettsAges 50–100 - NCT06598423Recruiting
Wavelength lenses for nearsighted kids
This study tests a special contact lens called 'Wavelength' to slow down nearsightedness (myopia) in kids. If your child already wears contacts and has certain levels of nearsightedness, they might be able to join.
Birmingham, AlabamaAges 7–12 - NCT06587113Recruiting
Study of attention and focus during visual search
This study explores how your brain focuses and ignores distractions while searching for things visually. It may help us understand attention processes in healthy adults.
Denver, ColoradoAges 18–65 - NCT06587945RecruitingPhase 4
Nicotinamide riboside for retinal detachment repair
This trial tests if taking a daily supplement called nicotinamide riboside after retinal detachment surgery can help the eye heal better and see more clearly. It is for people who had a specific type of retinal detachment and have already had cataract surgery.
East Melbourne, VictoriaAges 18 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,760 recruiting ophthalmology studies from the U.S. registry right now, out of 2,756 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.