Medical genetics
Genetic & congenital clinical trials
Inherited and congenital conditions present from birth or written into the genes. We’re tracking 3,762 recruiting studies in this area right now.
By phase
- Not applicable2,682
- Phase 2280
- Phase 1239
- Phase 3209
- Phase 1/Phase 2208
- Phase 495
- Phase 2/Phase 349
Top conditions
- Sickle Cell Disease133
- Atopic Dermatitis124
- Congenital Heart Disease84
- Cystic Fibrosis77
- Down Syndrome51
- Genetic Disease42
- Cystic Fibrosis (CF)37
- Duchenne Muscular Dystrophy36
- Fabry Disease36
- Hemophilia A36
- Cardiac Amyloidosis35
- Retinitis Pigmentosa33
- Huntington Disease31
- Lynch Syndrome31
- Heart Failure30
- Bronchopulmonary Dysplasia29
- Congenital Diaphragmatic Hernia29
- Duchenne Muscular Dystrophy (DMD)29
Leading sponsors
- Assistance Publique - Hôpitaux de Paris57
- Mayo Clinic39
- Boston Children's Hospital38
- National Institute of Allergy and Infectious Diseases (NIAID)38
- IRCCS Azienda Ospedaliero-Universitaria di Bologna32
- Children's Hospital Medical Center, Cincinnati31
- Hospices Civils de Lyon29
- Children's Hospital of Philadelphia23
- National Human Genome Research Institute (NHGRI)23
- St. Jude Children's Research Hospital23
Where studies are running
- California325
- Maryland160
- Alabama133
- Massachusetts107
- Arizona88
- New York85
- Texas70
- Minnesota68
- Pennsylvania64
- Florida59
Recruiting studies3,762 total
- NCT07512934Recruiting
Pancreatic Function Study in Early Type 2 Diabetes
This study examines how the pancreas works in people newly diagnosed with type 2 diabetes. Researchers will assess pancreatic function to better understand early diabetes and potentially improve treatment.
Aktobe, AktobeAges 18–74 - NCT07503197Enrolling by invitation
Cholesterol cream for child eczema
This trial tests a 2% cholesterol cream to see if it helps children with mild to moderate eczema on their inner elbows. It's designed for Thai children aged 7 to 17 who are not using strong immune-suppressing drugs.
BangkokAges 7–17 - NCT07502586Recruiting
Genetic study for Turner syndrome and family
This study looks at the genetic causes of Turner syndrome. It involves people with Turner syndrome and their family members to learn more about the condition. If you or your family member has Turner syndrome, this study may help answer questions about genetics and health.
Bethesda, MarylandAges 1 day–110 years - NCT07502664Recruiting
A study on vision and navigation in inherited retinal disease
This study is looking at how people with inherited retinal disease that affects peripheral vision see and move around. It will test a new way to measure vision and navigation to see if it can help doctors understand how the disease affects daily life.
Irvine, CaliforniaAges 18 years+ - NCT07505797Recruiting
Ultrasound imaging study for suspicious breast lesions
This study is testing a new ultrasound device (ATUSA) to see how well it can image breast lesions that have been classified as suspicious (BI-RADS 4 or 5). If you have a recent finding that needs further evaluation, this research might help improve detection methods.
Sacramento, CaliforniaAges 18–94 - NCT06375239Recruiting
Study of tests for tracking vision in retinal disease
This study will check if certain vision tests work well in people with retinal diseases like retinitis pigmentosa or Stargardt. Results will help design future trials.
Irvine, CaliforniaAges 18 years+ - NCT06764602Recruiting
Kidney health in kids with tuberous sclerosis
This study looks back at medical records to see how many children with tuberous sclerosis complex (TSC) have kidney problems. It may help doctors understand how common kidney issues are in kids with TSC.
BolognaAges Up to 17 years - NCT07506109RecruitingPhase 2
Study of sintilimab, ipilimumab, cetuximab, and dabrafenib for advanced colorectal cancer
This trial tests a combination of four drugs for people with a specific type of advanced colorectal cancer that has a BRAF V600E mutation and is microsatellite stable. The goal is to see if this combination can shrink tumors or slow the cancer's growth.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07504614Enrolling by invitation
Comparing two types of tooth sealants for kids with MIH
This study tests whether a new pre-etched bioactive sealant works better than a standard resin-based one to protect permanent molars affected by molar incisor hypomineralization (MIH), a condition that makes teeth softer and more prone to cavities. It aims to find a more effective way to prevent decay in these vulnerable teeth.
IrbidAges 6–12 - NCT07502989Recruiting
Study of Muscle Health Using Electrical Impedance Myography
This study uses a simple electrical test (EIM) and an MRI scan to check muscle health in people with muscle diseases. It may help researchers learn how to measure muscle changes without a biopsy.
Boston, MassachusettsAges 18–89 - NCT07505342Recruiting
Remote study for myotonic dystrophy type 1
This study tests whether remote assessments can track myotonic dystrophy type 1 (DM1) and looks at genetic factors. It aims to find better ways to monitor the disease from home.
Rochester, New YorkAges 18–88 - NCT07504146Recruiting
The Orienting study: imaging in CPPD, gout, and OA
This study looks at imaging findings (ultrasound and X-rays) in people with CPPD, gout, or osteoarthritis. It aims to help doctors better identify these conditions early.
Milan, MilanoAges 18 years+ - NCT07498829Recruiting
Cancer risk genetic testing for people with female organs
This study offers free genetic testing to women, trans men, and non-binary people (with female reproductive organs) who have not had previous testing for certain cancer-related genes. It aims to find people at higher risk for cancer so they can take steps to prevent it or catch it early.
LondonAges 18 years+ - NCT00178594Recruiting
Testing bleeding and clotting issues in people
This study looks at how the body stops bleeding or forms clots in people with bleeding or clotting disorders. It may help researchers understand these conditions better and improve evaluation tests.
Houston, TexasAges 1 day–98 years - NCT05099874Recruiting
Computer training to improve attention in sickle cell disease
This trial tests whether a computer-based “attention control” training program can improve attention and daily functioning in children with sickle cell disease. To join, you must meet certain criteria and also pass an initial attention screening test during the study.
Washington D.C., District of ColumbiaAges 8–16 - NCT06765005RecruitingPhase 1/Phase 2
Study of MG-K10 for Teens with Moderate to Severe Eczema
This study tests a new injectable medication called MG-K10 for teens with moderate to severe eczema that hasn't been well controlled with creams. The goal is to see if it can safely reduce inflammation and improve skin symptoms.
Hangzhou, ZhejiangAges 12–18 - NCT06767605Recruiting
Spanish registry for autoimmune liver diseases
This study collects information from people with autoimmune or cholestatic liver diseases to better understand them and improve care. It does not test a new treatment, but your participation can help future research.
BarcelonaAges 18 years+ - NCT06768008Recruiting
Integrated care model for newborns with critical heart disease
This trial tests a coordinated treatment plan for newborns with critical congenital heart disease, starting before birth and continuing after delivery. It aims to improve outcomes for babies who need two-ventricle repair surgery.
BeijingAges 1 day–4 weeks - NCT07490444RecruitingPhase 2
Better glasses for children with Down syndrome
This trial tests a new way to make eyeglass prescriptions for children with Down syndrome, ages 5 to 12. The goal is to see if it improves their vision.
Columbus, OhioAges 5–12 - NCT07496463Enrolling by invitationPhase 2
Setmelanotide for weight loss in pseudohypoparathyroidism type 1a
This study tests an experimental medication called setmelanotide to see if it can help with weight loss in people who have pseudohypoparathyroidism type 1a (PHP1a), a rare genetic condition that often leads to obesity. The goal is to find a new treatment option for weight problems related to PHP1a.
Boston, MassachusettsAges Any age - NCT07493096Recruiting
Intensive therapy program for children with brain-based conditions
This trial tests an intensive therapy program designed to help children with brain-based conditions like cerebral palsy or autism improve their skills in movement, thinking, and daily activities. The program runs for 2 weeks with daily sessions, and researchers will check for changes in your child's abilities.
The Woodlands, TexasAges 4–12 - NCT07490522Recruiting
Remote monitoring for gout in primary care
This study tests whether a smartphone app can help your doctor monitor your gout and adjust your urate-lowering medication. It is a feasibility study, meaning it checks if the approach works well for patients.
OsloAges 18 years+ - NCT07497867Recruiting
Long-term study of Korean CADASIL patients
This study follows people with CADASIL over time to learn more about the condition. It may help researchers understand how CADASIL progresses and improve care for patients.
Jeju City, Jeju-doAges 19 years+ - NCT07491237Recruiting
Heart rhythm and function study
This study looks at how heart rhythm problems affect heart function. It may help doctors better understand and treat these conditions.
RomaAges 18 years+
Common questions
- How many genetic & congenital clinical trials are recruiting?
- Clin2 is tracking 3,762 recruiting medical genetics studies from the U.S. registry right now, out of 5,456 we cover in this area in total.
- What does “Genetic & congenital” cover here?
- Inherited and congenital conditions present from birth or written into the genes. We group each study into genetic & congenital based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a genetic & congenital trial near me?
- Use the search to filter genetic & congenital studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.