Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT04576130Recruiting
ICD study after cardiac arrest from an abnormal heart rhythm
This study looks at an implantable defibrillator (ICD) strategy in people who survived a cardiac arrest caused by an abnormal rhythm (ventricular fibrillation or ventricular tachycardia). It aims to reduce the risk of another dangerous rhythm after the blocked heart arteries are fully treated.
CopenhagenAges 18 years+ - NCT04577248Recruiting
Heart valve registry for people considering valve procedures
This study follows adults with leaky or narrowed heart valves who are being considered for a valve procedure. It helps doctors better understand patient outcomes and care decisions for these valve problems.
Munich, BavariaAges 18–110 - NCT04583800Recruiting
Tracking heart failure risk and memory change in diabetes
This study follows adults with type 2 diabetes to see who may develop heart problems and who may have memory or thinking changes over time. It may help doctors better predict risk and plan earlier support.
LilleAges 18 years+ - NCT04584632Recruiting
Stent-like device for blocked leg arteries in the thigh or knee
This trial studies a new stent-like vascular scaffold to improve blood flow in people with symptomatic blockage in the thigh/knee artery. It may help reduce symptoms from narrowed or blocked arteries, but you must meet several artery and health requirements.
Sydney, New South WalesAges Any age - NCT04590001Recruiting
Test MobiusHD device for certain heart failure patients
This trial studies whether the MobiusHD® implant can improve symptoms or function in people with heart failure who are still limited in everyday activity. You may be eligible if your heart failure tests show moderate heart weakness and you meet specific walking and lab criteria.
Darlinghurst, SydneyAges 18 years+ - NCT04591639Recruiting
DAPA test for diabetes and heart failure using body scans
This study tests how a medication called DAPA (an SGLT2 inhibitor) affects the body in people with heart failure (with or without type 2 diabetes), or in some people with type 2 diabetes only. It may help researchers understand who could benefit most and what changes happen in the heart, using specialized heart imaging.
Edinburgh, ScotlandAges 18 years+ - NCT04593498Recruiting
Test for abnormal heart rhythm triggers for some heart rhythm types
This study looks at people who have frequent abnormal signals from the upper heart (supraventricular extra beats or short runs) and how that relates to atrial fibrillation risk. If you qualify, you may help researchers understand better ways to prevent or manage certain heart rhythm problems.
StockholmAges 70–89 - NCT04594837Recruiting
Robotic ankle device therapy after stroke-related foot drop
This study tests a robotic ankle device to help improve walking in people after a stroke who still have foot drop (the foot doesn’t lift well). It may help strengthen or retrain walking patterns during recovery.
Baltimore, MarylandAges 18 years+ - NCT04595630Recruiting
Testing heart blood markers to spot early bypass blockage
This study checks whether heart blood tests can predict early blockage of a coronary bypass graft soon after bypass surgery. It may help doctors identify patients at higher risk sooner so they can monitor or treat problems earlier.
ZagrebAges 18 years+ - NCT04599621Recruiting
Testing treatment for heart pain with anxiety or depression
This trial looks at people who have coronary artery disease and unstable or certain stable chest-pain symptoms, especially when anxiety or depressive symptoms are also present. The goal is to see how the study approach helps heart symptoms when mental health symptoms occur at the same time.
SamarkandAges Any age - NCT04600089RecruitingPhase 2
Ketamine during aortic surgery to help prevent spinal nerve injury
This Phase 2 study tests whether ketamine, given during a specific type of major aortic surgery, can help prevent spinal “nerve injury” (called spinal prophylaxis). You might be considered because your planned surgery and current plan for spinal protection match the trial’s needs.
Lexington, KentuckyAges 18–90 - NCT04602338Recruiting
Imaging tests to better diagnose heart failure with preserved function
This trial uses several types of heart imaging to diagnose heart failure where squeezing function is still fairly normal. It may help doctors sort out what’s causing your symptoms and guide better care by comparing imaging findings across many patients.
Beijing, Beijing MunicipalityAges Any age - NCT04602325Recruiting
Blood and brain injury biomarker study for inherited metabolic disorders
This trial studies blood and other measurable signs (biomarkers) that may reflect brain injury after certain inherited metabolic conditions. Results may help doctors better detect and understand brain effects from these illnesses, especially episodes that affect the brain.
Washington D.C., District of ColumbiaAges 7–18 - NCT04603404Recruiting
Imaging tests to find and predict HFpEF risk
This study uses different heart imaging tests to help screen for HFpEF (heart failure with preserved pumping strength), make the diagnosis, and estimate your future risk. You may benefit by getting a clearer diagnosis and a better risk picture based on the scans.
Beijing, Beijing MunicipalityAges Any age - NCT04603872RecruitingEarly Phase 1
CAR-T plus dasatinib for hard-to-treat B-cell cancers
This early study tests a cancer-fighting treatment that uses CAR-T cells together with dasatinib for people whose B-cell cancers have come back or did not respond. It aims to improve control of the cancer in cases that are often resistant to standard treatment.
Hangzhou, ZhejiangAges 18–70 - NCT04604782RecruitingPhase 1/Phase 2
Regadenoson study in children to test safety and dosing
This trial tests how safe regadenoson is in children and how the body handles it after dosing. It also uses a heart “stress test” with MRI (CMR) when doctors feel it’s needed.
ParisAges 4 weeks–18 years - NCT04606693Recruiting
Screening for sleep apnea before heart rhythm ablation
This study looks at whether checking for sleep apnea (breathing pauses during sleep) and treating it helps people prepare for atrial fibrillation ablation. It may help by improving outcomes for patients with atrial fibrillation who keep having episodes despite medication.
Madrid, MadridAges 18 years+ - NCT04606459Recruiting
Device trial for hard-to-treat heart chest pain from small vessels
This trial tests whether a small pressure-reducing device placed in a heart vein (the coronary sinus) can reduce symptoms in people with ongoing chest pain from tiny blood vessel problems. It is for angina that has not improved despite standard heart medicines, and only if special heart tests show reversible reduced blood flow.
Mainz, Rhineland-PalatinateAges 18–85 - NCT04606732Recruiting
Tracking heart risk changes after COVID-19 hospitalization
This study looks at how COVID-19 affects heart health over time in people who were hospitalized. Your results may help doctors predict prognosis and understand who is at higher heart risk after recovery.
BolognaAges 18 years+ - NCT04611516Recruiting
Study of ear, nose, and throat checks in PCD patients
This study follows people with primary ciliary dyskinesia (PCD) and looks at their regular ear, nose, and throat (ENT) checkups over time. Your participation may help doctors better understand how ENT care should be followed in PCD.
BernAges Any age - NCT04613193Recruiting
Lower blood pressure to study outcomes in mild valve narrowing
This trial studies whether lowering blood pressure affects health outcomes in people who have valve narrowing in the heart but no valve symptoms yet. It may help you understand which blood pressure targets are safest when the aortic valve is not fully opening.
AarhusAges 18 years+ - NCT04612296Recruiting
Heart Hive study for cardiomyopathy and family history
This observational study looks at people with cardiomyopathy or myocarditis, and people with a close family history of these conditions. It aims to better understand the condition and what factors may be involved.
LondonAges 18 years+ - NCT04612322Recruiting
Study registry for microvascular angina patients
This registry study collects information from adults with microvascular angina (chest pain from small blood vessels in the heart). It may help researchers better understand how to assess and manage this condition over time.
Mainz, RLPAges 18–85 - NCT04615130Recruiting
Pulmonary rehab for symptoms after a lung blood clot
This trial studies a structured pulmonary (lung) rehabilitation program for people who still have breathing and activity problems after a pulmonary embolism (PE). It may help improve physical ability and function during recovery.
ViennaAges 18–90
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.