Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT04533217Recruiting
Vertebroplasty for multiple myeloma back pain
This trial tests whether adding a procedure called vertebroplasty to usual care can better reduce back pain from multiple myeloma. It’s for people who have a small number of spine fractures in a specific area and significant pain.
Middelfart, Region SyddanmarkAges 18 years+ - NCT04537403RecruitingPhase 1
PET scan study of artery inflammation marker in plaque
This Phase 1 study tests whether a special PET scan can detect a specific inflammation signal (CCR2) in atherosclerosis—fatty plaque buildup in blood vessels. It may help future doctors better see which plaques are more inflamed and potentially more dangerous.
St Louis, MissouriAges 18–89 - NCT04538937Recruiting
Study of high eosinophils causing lung/airway damage
This registry study looks at adults with high eosinophils (a type of immune cell) that are believed to be causing damage in the airways or lungs. It aims to better identify these eosinophils and understand what is going on so future treatments can improve.
InnsbruckAges 18 years+ - NCT04544527Recruiting
Study risks for heart disease in older people with diabetes
This study follows older adults with diabetes to understand what factors may raise the risk of heart disease. It may help doctors spot risks earlier in people like you.
Suzhou, JiangsuAges 65–100 - NCT04546126RecruitingEarly Phase 1
PET scan study tracking cholesterol movement in your body
This early study uses a special PET scan dye to see how cholesterol moves through the body. It is testing how the imaging works in healthy people and in people with adrenal gland hormone secretion problems, to better understand cholesterol handling.
Ann Arbor, MichiganAges 18 years+ - NCT04550728RecruitingPhase 1/Phase 2
Robot training plus electrical stimulation after stroke
This trial tests a “hybrid” rehab program that combines robot-assisted walking practice with electrical stimulation to help movement after stroke. It may help people improve walking and leg function at home as they work with a caregiver.
Baltimore, MarylandAges 18–85 - NCT04547439RecruitingPhase 2
Melatonin for diabetic eye disease and better sleep
This Phase 2 study tests whether melatonin can improve sleep and possibly outcomes related to diabetic retinopathy (damage to the retina from diabetes). It also checks whether it affects related symptoms while keeping people safe.
Chicago, IllinoisAges 40–65 - NCT04552275RecruitingPhase 1
Biomarker study during valve replacement for older adults
This Phase 1 study looks at changes in the body’s “biomarkers” (measurable signs in blood/medical tests) in older people who are getting a specific type of valve replacement. Results may help doctors better monitor or understand outcomes after this valve procedure.
Boston, MassachusettsAges 65 years+ - NCT04555161Recruiting
Test of an implanted device for pulmonary arterial hypertension
This trial studies an implanted system (the Aria CV Pulmonary Hypertension System) to treat pulmonary arterial hypertension, a serious lung-blood vessel and heart condition. It aims to see whether the device can improve outcomes for people who are still sick despite existing PH medicines.
La Jolla, CaliforniaAges 18 years+ - NCT04554277Recruiting
Blood test-guided care for people hospitalized with heart failure
This study checks whether using a specific blood test (called sST-2) to guide heart-failure treatment leads to better care and outcomes. It may help by tailoring treatment decisions based on your test results.
Montpellier, OccitanieAges 18 years+ - NCT04556188Recruiting
Study to improve cardiac surgery services for rheumatic heart disease
This study looks at whether building a better, sustainable cardiac surgery service can reduce the burden of rheumatic heart disease. It focuses on patients who need cardiac surgery at a specific hospital during a training and research program.
Addis AbabaAges 14 years+ - NCT04557618Recruiting
Ear nerve stimulation after a brain bleed
This trial studies whether stimulating a nerve near the ear (auricular VNS) can help after a spontaneous subarachnoid hemorrhage, a type of bleeding around the brain. If you qualify, you may receive the ear stimulation as an added treatment while doctors monitor your recovery.
St Louis, MissouriAges 18 years+ - NCT04558931RecruitingPhase 2
NK cell therapy to help control multiple myeloma after initial treatment
This Phase 2 trial tests using your own immune cells (NK cells) alone or with isatuximab as “maintenance” treatment to help multiple myeloma stay under control after initial therapy. It may help lengthen the time until the disease grows again by boosting your immune response and targeting myeloma cells.
StockholmAges 18 years+ - NCT04559243Recruiting
Left atrial appendage closure to prevent stroke in AF
This study tests whether closing a heart pocket called the left atrial appendage can lower future stroke or other clot-related events in people with atrial fibrillation. It’s mainly for people who have had a prior clot-related event or are at higher risk but may not be good candidates for long-term blood thinners.
Jinan, ShandongAges 18 years+ - NCT04559425Recruiting
Registry study for immune-related serious slowed fetal heart rhythm
This study follows pregnancies where the baby has a serious immune-related heart rhythm problem (high-grade AV block). It collects information to better understand what happens during pregnancy and after delivery, especially when blood tests show anti-Ro/La antibodies.
Phoenix, ArizonaAges 16–50 - NCT04559373Recruiting
Virtual reality training to improve community walking after stroke
This trial tests whether virtual reality plus field (real-world) practice can improve walking and related thinking/vision skills after stroke. It may help you walk more safely and confidently in everyday community settings (like getting around outdoors).
Laval, QuebecAges 40–74 - NCT04560140Recruiting
Support after stroke to help young adults return to daily life
This study tests a community program to help young adults after a stroke rebuild independence at home and back to normal routines. It’s aimed at people who still need support with daily activities but are able to join all sessions and communicate in Cantonese.
Hong KongAges 18–64 - NCT04562194Recruiting
Registry study for people already treated with NeVa thrombectomy
This registry study follows people who have already had a specific clot-removal procedure using the NeVa device. It helps doctors understand how the device performs in real-world care for certain kinds of stroke.
MendozaAges 18 years+ - NCT04566991RecruitingPhase 2
Deferoxamine after aneurysm brain bleed to improve recovery
This trial studies deferoxamine, a medicine that targets iron-related injury, in people with an aneurysmal subarachnoid hemorrhage (a brain bleed caused by a burst aneurysm). It aims to improve neurologic recovery after the aneurysm is treated.
Ann Arbor, MichiganAges 18–80 - NCT04569006Recruiting
MRI comparison for thick carotid artery plaque
This study uses MRI scans to compare different MRI methods in people who have a thick plaque in the carotid artery (the main artery in the neck). It may help improve how doctors “see” plaque, which could support better risk assessment.
Maastricht, LimburgAges 18 years+ - NCT04570163Recruiting
Registry tracking right-heart valve procedures and outcomes
This is a registry that collects information about people who have planned or recent right-heart valve procedures (such as tricuspid or pulmonary valve problems). It helps researchers understand what care is done and how patients do over time, which may improve future treatment planning.
BerlinAges 18–120 - NCT04573660Recruiting
Registry for people using Abbott vascular devices
This is a patient registry that collects health information from adults who get Abbott vascular devices during a planned procedure. It helps Abbott and doctors understand how these devices perform in everyday care.
Birmingham, AlabamaAges 18 years+ - NCT04574037Recruiting
Predicting arm recovery after stroke
This study tries to predict how well your arm movement may improve after a stroke. It uses brain and/or nerve testing (like MRI and TMS) and could help doctors plan the best rehabilitation for you.
ParisAges 18 years+ - NCT04575883Recruiting
Bike interval training for teens with repaired heart defects
This study tests a structured “interval” bike exercise program to see if it’s safe and helpful for teens with certain repaired congenital heart conditions. It may help improve fitness while closely monitoring heart symptoms during training.
Edmonton, AlbertaAges 10–18
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
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- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.