Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT07448935Recruiting
Understanding a gene's role in AL amyloidosis and POEMS
This study looks at how a specific gene (IGLV1-44) affects two rare diseases: AL amyloidosis and POEMS syndrome. It involves a blood draw and possibly a bone marrow sample to learn more about how the gene works in these conditions.
PaviaAges 18–99 - NCT07450222Enrolling by invitation
Improving high blood pressure care
This trial studies a new way to help people with high blood pressure get better control of their numbers. It uses a team approach to support you in managing your blood pressure and lowering your risk for heart problems.
Peoria, IllinoisAges 18 years+ - NCT07447908Recruiting
Understanding worsening heart failure after leaving the hospital
This study monitors heart failure patients after a hospital stay or urgent clinic visit to better understand the signs of worsening heart failure. It may help researchers find ways to predict and prevent future exacerbations.
Newmarket, OntarioAges 18 years+ - NCT07445438Recruiting
A multi-omics study for blood cancers
This study is testing whether a complete platform that analyzes multiple molecular levels (multi-omics) can be used to better understand and diagnose blood cancers (hematological malignancies). It looks at samples from the blood, bone marrow, and tissues to help with initial diagnosis or when cancer returns after treatment.
Parma, PRAges 2 years+ - NCT07445347Enrolling by invitation
Bevacizumab for severe HHT liver issues with high heart output
This study looks at how well the drug Bevacizumab works and how safe it is for people with HHT who have severe liver problems that cause their heart to pump too much blood. It aims to help doctors understand if this treatment can help manage these serious symptoms.
PoitiersAges 18 years+ - NCT07451457Recruiting
Structured education program for heart failure patients
This trial tests if a structured education program helps people with heart failure manage their condition better. If you have been hospitalized for heart failure or are treated at a heart failure clinic, you may be able to join and learn more about your care.
BudapestAges 18 years+ - NCT07451873Recruiting
Glycocalyx and stress in blood vessel function (Part 2)
This study looks at how a protective layer inside your blood vessels (the glycocalyx) and oxidative stress affect blood vessel function after heart bypass surgery. The goal is to better understand why some people recover differently.
OsijekAges 18 years+ - NCT07446777Recruiting
Fasting and Mediterranean diet for multiple myeloma
This study tests whether a special diet—longer nightly fasting plus a Mediterranean eating pattern—can help people with multiple myeloma or its early stages. If you qualify, you will be randomly assigned to start the diet right away or join a waitlist group.
Miami, FloridaAges 18 years+ - NCT07445841Recruiting
Exercise to protect the brain after a first stroke
This trial tests whether a structured exercise program can help prevent thinking and memory problems after a first stroke. It might help you keep your brain healthy if you join within the first six months after your stroke.
Hamilton, OntarioAges 40–80 - NCT07453381Recruiting
New catheter to check small heart vessels in people with chest pain
This trial tests a special wireless pressure catheter to see how well the tiny blood vessels in the heart are working. It may help people who have chest pain but don't have major blockages in their main heart arteries.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07450911RecruitingPhase 1
Mitral valve replacement with the ReValve system
This study is for people with severe mitral valve leakage (mitral regurgitation) who may need a valve replacement. It tests whether the ReValve system is safe and can help improve symptoms and heart function.
TbilisiAges 18 years+ - NCT07452198RecruitingPhase 3
Study of new drug for relapsed or hard-to-treat multiple myeloma
This trial tests a new medicine (GR1803) against a standard combination treatment for people whose multiple myeloma has come back or stopped responding to prior therapies. It aims to see if the new drug works better.
TianjinAges 18 years+ - NCT07448038RecruitingPhase 2
Study of an anti-inflammatory pill for heart artery health
This trial tests a pill that may reduce inflammation in blood vessels, which could lower the risk of heart attacks or strokes in people with atherosclerosis. It could help if you have plaque in your arteries and are at risk for major heart events.
Beverly Hills, CaliforniaAges 18 years+ - NCT07448623RecruitingPhase 1
Testing coramitug for ATTR amyloid heart disease
This study tests a new medication called coramitug to see if it can reduce abnormal protein deposits in the heart. You will have special PET/CT scans to measure how the drug affects these deposits.
GroningenAges 60 years+ - NCT06128993Recruiting
cooling the heart during heart attack treatment
This trial tests a new way to protect the heart during emergency angioplasty by gently cooling the heart with a cold fluid. It may help reduce damage from a heart attack if you are treated within 12 hours.
UxbridgeAges 18 years+ - NCT06769529Recruiting
Study of adults with congenital heart disease
This study follows adults born with a heart condition to see how they do over time, whether they had surgery or not. It aims to learn more about their health journey.
BolognaAges 18 years+ - NCT06433401Recruiting
Structured transition care for teens with heart disease
This study tests a structured transition care model to help teenagers with congenital heart disease move from pediatric to adult care. It aims to make the process smoother and improve your health outcomes.
Ankara, Ankara YenimahalleAges 16–20 - NCT06300762Recruiting
Wound dressing for leg ulcers
This trial tests a new wound dressing for leg ulcers. It aims to see if the dressing helps manage fluid and heal the ulcer better than standard care. You may be a candidate if you have a leg ulcer that needs compression therapy.
Melle, NiedersachstenAges 18 years+ - NCT06803550Recruiting
Recovery program after anal surgery
This trial tests a special recovery program after surgery for common non-cancerous anal conditions like hemorrhoids, anal fissures, or fistulas. The goal is to see if this approach helps you heal faster and feel better.
Al MansurahAges 18–65 - NCT06585228Recruiting
Heart CT vs ultrasound to find clots after stroke
This study compares two ways to look for blood clots in the heart after a stroke: a heart CT scan and an ultrasound done through the food pipe. It aims to see if the CT scan can spot clots just as well as the more invasive ultrasound.
Amsterdam, North HollandAges 18 years+ - NCT06803849Recruiting
Biomarkers and pregnancy history for heart failure prognosis
This study looks at whether certain substances in the blood and your history of pregnancy complications can help predict the course of heart failure with preserved ejection fraction (a type of heart failure where the heart pumps well but doesn't relax properly). It may help doctors better understand and manage this condition in older women.
MoscowAges 60–74 - NCT06802016Recruiting
Study of Chinese congenital bicuspid aortic valve
This study looks at people with a bicuspid aortic valve (a valve with two flaps instead of three) in Chinese patients. It collects information about this condition to better understand it.
Shanghai, Shanghai MunicipalityAges 14–60 - NCT06804148Recruiting
Myval heart valve registry in Germany
This registry tracks people getting a new heart valve called Myval. It's designed to see how well it works in real-world care.
Lübeck, Schleswig-HolsteinAges 18 years+ - NCT06804980RecruitingPhase 4
Rosuvastatin Tolerance for People with Statin Side Effects
This trial tests a low dose of rosuvastatin (a common statin) in people who have had trouble with statins before. The goal is to see if your body can tolerate this specific dose again, which could help lower your cholesterol without the past side effects.
Minneapolis, MinnesotaAges 21 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.