Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT04815928Recruiting
Registry for people after heart artery procedures
This study is a patient registry that collects information from adults who have had (or will have) two types of heart procedures done to check and treat blocked coronary arteries. It helps doctors understand outcomes and care patterns after these procedures.
AmsterdamAges 18 years+ - NCT04820764Recruiting
Testing a device to treat leaking mitral valve
This study looks at how long a new mitral valve treatment/device can stay working in people with moderate-to-severe or severe mitral valve leak. It may help avoid or delay surgery for people considered higher risk for mitral valve repair.
Thousand Oaks, CaliforniaAges 18 years+ - NCT04823299Recruiting
Atrial fibrillation ablation using two different energy types
This trial tests whether one ablation approach works better than another for paroxysmal (intermittent) atrial fibrillation by targeting the heart’s “triggers” and “substrate” (where the rhythm problem is). If you qualify, you’ll be randomly assigned to one of two ablation energy methods during a pulmonary vein isolation procedure.
Ottawa, OntarioAges 18 years+ - NCT04822077Recruiting
Proton beam treatment for thymus tumors
This trial studies proton radiotherapy (a type of radiation) for cancers of the thymus, like thymoma or thymic carcinoma. It may help improve tumor control while limiting radiation exposure to nearby organs.
Umeå, NorrlandAges 18 years+ - NCT04824482Recruiting
Robot training to improve walking after a recent stroke
This study tests a robot-assisted walking program for people recovering after an acute ischemic stroke. It aims to improve how safely and independently you can walk during recovery.
OlomoucAges 18–80 - NCT04827498Recruiting
Testing heart blood-flow problems without clogged arteries
This study looks at how well the heart’s blood vessels work in people who have symptoms of reduced blood flow but no major artery blockage. It uses special heart tests with medicines to check how the vessels respond and may help guide better diagnosis and treatment.
MadridAges 18 years+ - NCT04827316Recruiting
Use CT heart scans to predict outcomes and guide care
This study looks at people who are having a CT scan of their heart because it’s medically needed. Researchers will use the scan results to better predict future cardiovascular outcomes and improve how care decisions are made.
BernAges 18 years+ - NCT04829071RecruitingEarly Phase 1
Testing brain and movement training after a one-sided stroke
This early research study looks at a way to improve thinking and movement after a stroke that happened more than 6 months ago. It may help people who still have problems using one side of their body to walk and learn new movement skills.
Los Angeles, CaliforniaAges 45–85 - NCT04829617Recruiting
Program to improve daily habits in heart failure
This trial studies a program designed to help people with heart failure improve health habits like diet, exercise, and taking medicines. It may help you feel better and stay on track if your current routines are hard to follow.
Boston, MassachusettsAges 18 years+ - NCT04830137RecruitingPhase 1
Test drug NX-2127 for hard-to-treat B-cell blood cancers
This Phase 1 trial tests the safety and early effectiveness of NX-2127 in adults with relapsed or refractory B-cell cancers. If you qualify, you may receive a new targeted treatment because your cancer has returned or not responded to prior therapies.
Duarte, CaliforniaAges 18 years+ - NCT04832009RecruitingEarly Phase 1
Test a way to improve blood vessel function with lifestyle
This early-phase study looks at whether a treatment can help reverse problems in blood vessels caused by high glucose (sugar) and blood fat signals. It may be a fit if you are generally healthy, have normal insulin and sugar levels, and have a stable weight.
Kansas City, KansasAges 18–79 - NCT04833751Recruiting
Study of heart and brain monitoring around heart surgery anesthesia
This study collects heart and brain signal information before and during anesthesia for people having cardiovascular surgery or procedures. The goal is to better understand risk and outcomes, and to improve how anesthesia is assessed.
SeoulAges 19 years+ - NCT04835857Recruiting
Testing a cuff-less wrist monitor versus a regular blood pressure cuff
This study compares a cuff-less wrist blood pressure device to the usual arm cuff. You may be able to help test whether the wrist device reads blood pressure accurately and safely.
Newton, MassachusettsAges 18–90 - NCT04838249Recruiting
Hormone therapy study on eating, energy, and heart health
This study looks at how cross-sex hormone therapy affects appetite (eating behavior), metabolism (how your body uses food), energy balance, and cardiovascular (heart and blood vessel) health. You may be included if you meet specific health and safety requirements and can follow study procedures.
Leipzig, SaxonyAges 18 years+ - NCT04839887Recruiting
Quality of life after stroke in adults aged 18–65
This trial looks at what affects quality of life after an ischemic stroke (a type of stroke caused by a blocked blood vessel) in younger adults. You may be able to join if you can complete questionnaires about your recovery and daily life.
OlomoucAges 18–65 - NCT04843371Recruiting
Using wearable data to predict heart pump strength
This trial tests whether a wearable device (Biostrap) can help predict how strongly your heart pumps, using echocardiogram (heart ultrasound) results. It may help doctors better estimate heart function from simpler measurements.
New Orleans, LouisianaAges 18–120 - NCT04843683Recruiting
Stereotactic radiation treatment for abnormal heart rhythms
This trial studies using a precise type of radiation (stereotactic ablative radiotherapy) to treat abnormal heart rhythms when medicines or prior procedures haven’t worked. It may help by targeting the heart area causing the rhythm problem without doing another invasive ablation.
Toronto, OntarioAges 18 years+ - NCT04844151Recruiting
Registry study for acute myocarditis with heart imaging
This study collects information from people with newly diagnosed acute myocarditis using heart scans and, in some cases, a biopsy. It aims to understand what predicts recovery and which test results matter most for outcomes.
ParisAges 15 years+ - NCT04844801Recruiting
Prevent fast heart rhythms during sepsis shock with rate control drugs
This trial tests whether a heart-rate–controlling medication can better manage a new fast heart rhythm that happens during sepsis shock. It may help reduce heart strain and improve safety compared with standard care.
ParisAges 18 years+ - NCT04844944Recruiting
Heart registry for adults with heart failure, CAD, or atrial fibrillation
This is a hospital-based study that collects standardized information about adults with specific heart conditions—heart failure, coronary artery disease, or atrial fibrillation. It may help doctors and researchers better understand these diseases and improve future care.
BerlinAges 18 years+ - NCT04847752Recruiting
Predicting outcomes after stroke from artery plaque
This study looks at factors that can help predict recovery and risk after an ischemic stroke caused by plaque buildup in a major artery. It may help doctors better forecast prognosis and tailor follow-up care for people like you.
WuhanAges Up to 80 years - NCT04848844Recruiting
Congenital heart disease transplant registry study for adults
This study collects and shares anonymous information about adults being considered for a heart transplant because of a congenital (from birth) heart problem or an inherited heart muscle condition. The goal is to better understand these patients and support research that may improve care.
HamburgAges 18 years+ - NCT04851886Recruiting
Vision tool to guide robot therapy for stroke arm posture
This trial tests a vision-based system that detects your arm and posture during robot-assisted upper-arm therapy after a prior stroke. It may help the robot guide treatment more safely and accurately based on your movements and positioning.
Charlestown, MassachusettsAges 18–80 - NCT04856059Recruiting
MRI study for early heart changes in Fabry disease
This study looks at early structural and tissue changes in the heart using a special type of MRI scan in adults with Fabry disease. It may help doctors understand changes earlier and better track heart involvement over time.
Toronto, OntarioAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.