Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT07421076Recruiting
Grid mapping study for atrial fibrillation ablation
This trial tests a new mapping tool to help doctors find and treat the source of atrial fibrillation (AF) during a standard ablation procedure. It may offer a more precise way to guide treatment for people with AF that comes and goes.
Jinan, ShandongAges 18 years+ - NCT07425171Recruiting
Testing a drug-coated balloon for long leg artery blockages
This trial is testing a special balloon coated with the drug paclitaxel to open up long blockages in the leg artery (femoropopliteal). The goal is to see if it is safe and effective for improving blood flow and symptoms like pain or ulcers.
Suwon, Gyeonggi-doAges 19–85 - NCT07420907Recruiting
Tracking heart health over time
This study uses a wearable patch to monitor heart-related signs in people with heart conditions. It aims to learn more about how these conditions progress, which could help improve future care.
Chicago, IllinoisAges 18 years+ - NCT06817148Recruiting
TAVR vs surgery for bicuspid aortic valve disease
This study compares two treatments for severe aortic stenosis in people with a bicuspid aortic valve: transcatheter aortic valve replacement (TAVR, a less invasive procedure) and surgical aortic valve replacement (SAVR, open-heart surgery). The goal is to see which approach works better for this specific condition.
Los Angeles, CaliforniaAges 50 years+ - NCT06817434Recruiting
Statin treatment for Moyamoya disease study
This study tests if statins (cholesterol-lowering drugs) can help people with Moyamoya disease. The trial will follow patients who receive either surgery or standard care to see if adding a statin improves outcomes.
Beijing, ChinaAges 18–60 - NCT06818149Recruiting
Studying heart inflammation from immunotherapy in lung cancer
This study looks for specific markers in the blood that can help doctors better understand and treat heart inflammation (myocarditis) caused by immunotherapy in people with lung cancer. If you join, you will help find ways to improve care for other patients.
ShanghaiAges 18 years+ - NCT04567121Recruiting
Online lifestyle program to lower common health risk factors
This trial tests an internet-based coaching program to help people with lifestyle-related risk factors (like high blood pressure, diabetes risk, smoking, or fatty liver) improve their health. It may help you better manage risk factors that can lead to heart and other long-term diseases.
Beijing, Beijing MunicipalityAges 25 years+ - NCT04399200Recruiting
Study apnea after stroke to prevent new heart events
This trial looks at sleep apnea (breathing pauses during sleep) in people soon after a first stroke or a TIA, to see if it can be linked to new cardiovascular (heart/blood vessel) events. It also aims to make sure you can safely follow the study and rehabilitation plan.
GrenobleAges 18–85 - NCT07425132Recruiting
Non-invasive heart mapping for congenital heart disease
This trial tests a new, non-invasive way to create detailed 3D maps of the heart's electrical activity in people with congenital heart disease. It aims to help guide procedures like heart catheterization or device implantation, potentially making them safer and more personalized.
Madrid, MadridAges 18–80 - NCT07424885Recruiting
Comparing two stent grafts for complex aneurysm repair
This study compares two types of stent grafts used during a minimally invasive aneurysm repair (FEVAR). It is for people with complex aneurysms (near the kidneys or in the chest/belly area) who need surgery soon.
Vienna, State of ViennaAges 18 years+ - NCT07422129Recruiting
Aortic wall analysis during heart surgery
This study looks at the structure and strength of the aorta (the main artery from your heart) in patients having surgery to replace part of it or having a heart transplant. The goal is to better understand the aortic wall to improve future treatments.
Pavia, LombardyAges 18 years+ - NCT07424690Recruiting
Comparing ablation with medication care for older adults with atrial fibrillation
This study compares two approaches for older adults with atrial fibrillation: a procedure called catheter ablation (which uses heat or cold to fix the heart's rhythm) versus conservative care (medications and lifestyle changes). The goal is to see which approach is better for improving quality of life and reducing symptoms in people aged 78 and above.
LinköpingAges 78 years+ - NCT07420400Recruiting
Detecting heart shunts without needles
This trial uses a specialized ultrasound test (TEE with bubble study) to find a small opening in the heart called a PFO. It may help people who need this test to check for causes of certain health problems.
La Jolla, CaliforniaAges 18 years+ - NCT07420465Recruiting
Heart and metabolic risks in pregnancy and after birth
This study looks at heart and metabolic health during late pregnancy and after delivery, tracking both healthy women and those with complications like high blood pressure or diabetes in pregnancy. The goal is to understand how these risks change and what can be done to improve long-term health.
AccraAges 18–45 - NCT07420959RecruitingPhase 1/Phase 2
ABBV-383 for Waldenström macroglobulinemia that came back
This trial tests a new drug called ABBV-383 for people with Waldenström macroglobulinemia that has returned or stopped responding to treatment. The drug is given as an infusion and aims to attack the cancer cells. This might help if you've already tried a BTK inhibitor.
Rochester, MinnesotaAges 18 years+ - NCT07420023Recruiting
Nutrition study for weight management and fullness
This study tests a special food product and meal plan to help people feel fuller longer and control appetite. It may help you understand how certain foods affect your body and weight.
CorkAges 18–45 - NCT07421453Recruiting
Better recovery plan for draining brain blood clots
This trial is testing a new, step-by-step care plan (called an enhanced recovery pathway) for people who need a small hole drilled in their skull to drain a slow-growing blood clot (chronic subdural hematoma). The goal is to see if this organized approach helps patients recover faster and feel better.
LeuvenAges 18 years+ - NCT07420088Recruiting
Seasonal activity in heart failure with a heart device
This trial studies how physical activity changes with the seasons in people with heart failure who have a pacemaker or defibrillator. It aims to help doctors understand how to better support your activity levels throughout the year.
ÇorumAges 18 years+ - NCT07424326Recruiting
Extended ablation vs. standard treatment for persistent atrial fibrillation
This trial compares two catheter ablation techniques for people with persistent atrial fibrillation (a type of irregular heartbeat that doesn't go away on its own). It will test whether a more extensive ablation (burning more heart tissue) works better than the standard procedure of isolating the pulmonary veins (the veins that bring blood from the lungs to the heart). If you have this condition and have had at least one episode in the past year, this study might help you find a more effective treatment.
OlomoucAges 18–80 - NCT07419087Recruiting
French trunk impairment scale adaptation and validation study
This study aims to adapt and validate a French version of the Trunk Impairment Scale, a tool that measures how well stroke survivors can control their trunk (core body) movements. Participating will help researchers improve stroke recovery assessments.
Ploemeur, Please Choose...Ages 18–85 - NCT07417462Recruiting
Pain relief after heart surgery to help you recover faster
This trial tests a combination of pain medicines given during cardiac surgery to reduce pain and speed up recovery. It may help patients who are having a first-time bypass surgery through a standard breastbone incision.
AsyutAges 40–60 - NCT07418099Recruiting
Study on a blood test for prolonged clotting time
This study looks at a special blood test (clot waveform analysis) to see if it can help doctors better understand why some people have a prolonged clotting time. This might help them find the cause more quickly and accurately.
Leganés, MadridAges Any age - NCT07417410Recruiting
Diabetes eye disease risk study
This study looks back at medical records of people with type 2 diabetes to understand how diabetic eye disease (retinopathy) progresses and when treatment is needed. It may help doctors better predict risks and guide future care.
Portugal, Coimbra DistrictAges 35–90 - NCT07421882Recruiting
Cooling after cardiac arrest to improve brain recovery
This trial tests if starting body cooling before reaching the hospital can help protect the brain after a cardiac arrest. It is for adults who are unconscious after their heartbeat has been restored by emergency services.
SingaporeAges 16–80
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.