Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT07420959RecruitingPhase 1/Phase 2
ABBV-383 for Waldenström macroglobulinemia that came back
This trial tests a new drug called ABBV-383 for people with Waldenström macroglobulinemia that has returned or stopped responding to treatment. The drug is given as an infusion and aims to attack the cancer cells. This might help if you've already tried a BTK inhibitor.
Rochester, MinnesotaAges 18 years+ - NCT07416344Enrolling by invitation
Heart CT screening for high-risk rural patients
This trial uses a heart CT scan to find people in rural China who are at high risk for heart disease but haven't had a heart attack or stroke yet. The goal is to see if this screening can help guide treatment and prevent future heart problems.
Daqing, HeilongjiangAges 40–75 - NCT07424690Recruiting
Comparing ablation with medication care for older adults with atrial fibrillation
This study compares two approaches for older adults with atrial fibrillation: a procedure called catheter ablation (which uses heat or cold to fix the heart's rhythm) versus conservative care (medications and lifestyle changes). The goal is to see which approach is better for improving quality of life and reducing symptoms in people aged 78 and above.
LinköpingAges 78 years+ - NCT07424326Recruiting
Extended ablation vs. standard treatment for persistent atrial fibrillation
This trial compares two catheter ablation techniques for people with persistent atrial fibrillation (a type of irregular heartbeat that doesn't go away on its own). It will test whether a more extensive ablation (burning more heart tissue) works better than the standard procedure of isolating the pulmonary veins (the veins that bring blood from the lungs to the heart). If you have this condition and have had at least one episode in the past year, this study might help you find a more effective treatment.
OlomoucAges 18–80 - NCT07422129Recruiting
Aortic wall analysis during heart surgery
This study looks at the structure and strength of the aorta (the main artery from your heart) in patients having surgery to replace part of it or having a heart transplant. The goal is to better understand the aortic wall to improve future treatments.
Pavia, LombardyAges 18 years+ - NCT07420374Recruiting
Outpatient stroke care for older patients
This study tests whether older people with minor strokes or warning signs can be safely treated at home or in an outpatient clinic instead of staying in the hospital. It may be a good fit if you recently had a mild stroke and do not need complex medical care.
HeidelbergAges 60 years+ - NCT05339477Recruiting
Study of activity after a heart attack
This study follows people after a type 1 heart attack to see how physical activity relates to recovery. It may help doctors understand what activity patterns are best after hospitalization.
AlingsåsAges 18–79 - NCT06157437Recruiting
Focal pulse ablation for atrial flutter
This study tests a new device that uses focused pulses of energy to treat a common type of fast heartbeat called typical atrial flutter. It aims to see if this approach is safe and effective for people who have had at least one episode in the past 6 months.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06812455RecruitingPhase 4
Rivaroxaban for blood clot after heart catheterization
This trial tests if a blood thinner called Rivaroxaban can treat a blood clot that forms in the wrist artery after a heart catheterization. If you have this clot, taking Rivaroxaban may help reopen the artery and improve blood flow.
ThessalonikiAges 18 years+ - NCT06707662Recruiting
Pacing methods to protect heart function
This trial tests two pacing approaches to see which one better prevents weakening of the heart's main pumping chamber. It's for people who need a pacemaker for a slow heart rhythm and are expected to rely on it heavily.
BarcelonaAges 18 years+ - NCT06723145RecruitingPhase 4
Perioperative antiplatelet therapy for abdominal surgery after stent
This study looks at the best way to manage your blood-thinning medicine (antiplatelet therapy) around the time of abdominal surgery, if you have a coronary stent. The goal is to help reduce the risk of heart problems while keeping bleeding risks low.
KyotoAges 20 years+ - NCT06791681RecruitingEarly Phase 1
ESO-T01 for returning or hard-to-treat multiple myeloma
This trial tests a new treatment called ESO-T01 for people with multiple myeloma that has come back or is not responding to at least two prior therapies. It aims to see if this therapy is safe and can help control the disease.
Wuhan, HubeiAges 18 years+ - NCT06819436RecruitingPhase 4
Dexamethasone for spinal anesthesia side effects
This trial tests if a steroid called dexamethasone can prevent low blood pressure after spinal anesthesia for orthopedic surgery. If you are having hip, knee, or other bone surgery with spinal anesthesia and are otherwise healthy, this study may help reduce side effects.
Karachi, SindhAges 65–85 - NCT06816641Recruiting
Surgery for spontaneous brain bleed: outcomes and factors
This trial studies how well surgery works for people who have a spontaneous brain bleed (not from injury) and looks at factors that might affect recovery. It may help doctors better predict who benefits from surgery.
SohagAges 20–70 - NCT06819618Recruiting
Predicting heart failure outcomes with machine learning
This trial uses machine learning to analyze data from a smartwatch to predict how heart failure progresses. It may help doctors better understand your condition and tailor treatments.
Goettigen, Lower SaxonyAges 18 years+ - NCT03999983Recruiting
Procedure registry for blocked vertebral artery origins
This trial registry collects information on patients treated with a catheter-based procedure for narrowed or blocked vertebral artery openings in the back of the brain. It may help doctors better understand which patients benefit and how treatment is done, but it’s mainly about tracking outcomes and safety.
Jacksonville, FloridaAges 18–90 - NCT06031610Recruiting
Carotid artery opening study for brain health
This study tests if opening a narrowed carotid artery can reduce brain damage from small vessel disease. It may help patients with carotid artery narrowing prevent cognitive decline.
Hangzhou, ZhejiangAges 40–80 - NCT06306625Recruiting
Remote conditioning after out-of-hospital cardiac arrest
This trial tests a treatment that uses a blood pressure cuff on your arms to try to protect your brain and organs after your heart stopped outside the hospital. You will be in the intensive care unit, and the study will check if this simple 'remote conditioning' can improve recovery.
BronAges 18–80 - NCT07415447Recruiting
Aorta repair study: heart and vessel changes after stent procedure
This study looks at how the heart changes after a minimally invasive procedure to fix an aortic aneurysm. It uses imaging to track heart function and structure over time.
LisbonAges 18 years+ - NCT07407790Recruiting
Smartphone heart check after stroke
This study tests whether using a smartphone app to check your heart rhythm after a stroke can find hidden atrial fibrillation (an irregular heartbeat). If you had a recent stroke or TIA and are not already on blood thinners, you may be able to help doctors detect and prevent future strokes.
KristiansandAges 18 years+ - NCT07409519Recruiting
Nutrition Screening for Heart Disease Patients
This trial looks at how nutrition affects people with heart and blood vessel conditions. Anyone with cardiovascular disease can join—there are no strict medical rules.
Hull, E. Riding YorkshireAges 40–85 - NCT07413809RecruitingPhase 3
Preventing nausea after stem cell transplant: olanzapine vs dexamethasone
This trial compares two anti-nausea drug regimens (one with olanzapine, one with dexamethasone) to prevent delayed nausea and vomiting after a stem cell transplant for multiple myeloma. It aims to find which is better at controlling these side effects.
Ningbo, ZhejiangAges 18–65 - NCT07414342Recruiting
Study of RENATUS® valve for severe aortic stenosis
This study tests a new device called the RENATUS® Transcatheter Aortic Valve System for people with severe aortic stenosis. It is designed to replace the narrowed valve without open-heart surgery, and aims to see if it is safe and effective for patients with various surgical risk levels.
BeijingAges 60–100 - NCT07407738Recruiting
A trial of a shockwave device for calcified heart arteries
This trial tests a new device that uses sound waves to break up calcium deposits in heart arteries before placing a stent. It is for people with severely hardened arteries that are hard to treat with standard methods.
LyonAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
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- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.