Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT07431762RecruitingPhase 4
Aspirin vs. Warfarin after bioprosthetic valve surgery
This trial compares aspirin to warfarin in the first six months after receiving a bioprosthetic (tissue) heart valve. It aims to find which treatment better prevents blood clots without causing excessive bleeding.
OsakaAges 19 years+ - NCT07432607Recruiting
High-Flow Nasal Oxygen vs Face Mask for Heart Surgery
This trial compares two ways of giving oxygen during a heart surgery that uses small chest cuts. One method is a face mask, the other is a high-flow nasal tube. The study will see which keeps your oxygen levels better while you are awake but relaxed.
Istanbul, KARTALAges 18–75 - NCT07429227Recruiting
Gut health and heart disease: a probiotic study
This trial tests whether natural extracts and probiotics can improve gut health in people who have had a recent heart attack (Acute Coronary Syndrome). It uses special exams to measure changes in gut bacteria.
Peschiera del Garda, VeronaAges 30–70 - NCT07428967Recruiting
Pacemaker after heart procedure for atrial fibrillation
This trial tests a new type of pacemaker for people with atrial fibrillation who are scheduled for a procedure that disconnects the heart's natural electrical pathway. It may help improve symptoms and heart function.
HagenAges 18 years+ - NCT07431151Recruiting
Virtual reality training for balance after stroke
This study tests if using virtual reality headset games can help improve your balance, walking, daily activities, and quality of life after a recent stroke. If you join, you will do special balance and walking exercises with virtual reality.
Ankara, ÇankayaAges 18 years+ - NCT07428473RecruitingPhase 1
Study of STX-1150 for high cholesterol
This early-phase trial tests a new medication called STX-1150 for people with high LDL cholesterol. It aims to see if the drug is safe and how well it works to lower cholesterol.
Clayton, VictoriaAges 18–70 - NCT07427108Recruiting
Road map vs. ultrasound for retrograde leg angioplasty
This trial compares two imaging methods (road map vs. ultrasound) to guide a needle puncture from the ankle area during angioplasty for blocked leg arteries. It aims to see which method is safer and more effective for patients with severe leg wounds or ulcers that need this retrograde approach.
SohagAges 18 years+ - NCT07431229Recruiting
Nitrates for moderate-to-high risk pulmonary embolism
This trial tests whether a common food additive (nitrates) can help your heart recover faster when you have a serious pulmonary embolism. It is for people with a recent clot and signs of heart strain, but who are not on specific blood thinners or other nitrate medicines.
StockholmAges 18 years+ - NCT07434193Recruiting
Pacing study after aortic valve replacement
This trial tests if special pacing of the heart's lower chambers (called cardiac resynchronization therapy, or CRT) can help people who develop a new electrical delay in the heart after having a transcatheter aortic valve replacement (TAVI). The study compares two types of pacing to see which works better for recovery.
BudapestAges 18 years+ - NCT07430943Recruiting
Adding street racket to lung rehab
This trial tests if playing Street Racket (a simple sport similar to tennis) is possible and enjoyable for people already in pulmonary rehabilitation. You would play while wearing a portable oxygen backpack.
ZurichAges Any age - NCT06258681Recruiting
Breathing exercise device for recovery after heart surgery
This trial tests a new breathing exercise device designed to help your lungs recover after heart surgery. It may make your breathing easier and speed up your return to daily activities.
Istanbul, IstanbulAges 40–65 - NCT06353334RecruitingPhase 4
Butylphthalide for brain recovery after cardiac arrest
This trial tests if butylphthalide can improve brain function in people who have been resuscitated after a cardiac arrest. It may help reduce brain damage and improve recovery.
Beijing, Beijing MunicipalityAges 18–80 - NCT06737679Recruiting
Body scan therapy for heart failure patients
This trial tests whether a guided body scan can help people with heart failure better recognize their body's internal signals. It may improve how you understand and manage your symptoms.
Milan, ItalyAges 18–75 - NCT06805929Recruiting
Stroke recovery: brain signals and rehab results
This study looks at how brain signals and MRI scans change after a first stroke that affects the arm. It tests whether these signals can help predict how well rehabilitation will work.
Roma, ItalyAges 18 years+ - NCT06813534Recruiting
IVUS-guided stent placement for kidney disease patients
This trial tests whether using a special ultrasound camera inside the artery (IVUS) to guide stent placement can improve outcomes for people with serious kidney disease. The goal is to use less contrast dye and protect the kidneys better.
Créteil, CreteilAges 18 years+ - NCT06813443Recruiting
Studying cardiomyopathy to find who needs a heart transplant
This study is looking at people with cardiomyopathy to understand which patients are most in need of a heart transplant. By joining, you will help doctors learn more about critical cases and improve care for heart muscle disease.
Bologna, Emilia-Romagna/BolognaAges 12 years+ - NCT06814574Recruiting
Pacemaker after tricuspid valve replacement
This study looks at whether people who need a new tricuspid heart valve also need a pacemaker soon after. Researchers want to learn more about heart rhythm changes after valve replacement.
München, BavariaAges Any age - NCT06815159Recruiting
Tissue markers for early AV fistula narrowing
This study looks at tissue samples from people getting or fixing an AV fistula for dialysis. The goal is to find markers that might predict early narrowing (stenosis) of the fistula, so doctors can prevent problems in the future.
BolognaAges 18 years+ - NCT05597345RecruitingPhase 2
Selinexor for higher-risk smoldering myeloma
This trial studies selinexor, a medicine taken by mouth, to slow or treat intermediate- or high-risk smoldering multiple myeloma before it becomes symptomatic. It may help some people reduce disease progression, based on how well the treatment controls the abnormal plasma cells.
Rochester, New YorkAges 18 years+ - NCT06002932Recruiting
Comparing one-stent with drug balloon vs. two-stents for heart artery branches
This study compares two ways to treat a narrowed heart artery where a smaller branch vessel is also blocked. One approach uses a drug-coated balloon on the side branch, while the other places a second stent. The goal is to see which method works better for patients like you.
Suwon, Gyeonggi-doAges 19 years+ - NCT05739253Recruiting
Study how the aorta changes after a valve procedure
This trial looks at how the ascending aorta (the main artery near the heart) changes over time after transcatheter aortic valve replacement. It may help doctors predict who is at risk of aorta enlargement after this less-invasive valve procedure.
Beijing, Beijing MunicipalityAges Any age - NCT06365099RecruitingPhase 1
Brain state test for arm recovery after stroke
This study tests whether we can use brain scans to predict when your brain is ready to move your weak arm after a stroke. It uses a safe, non-invasive technique called transcranial magnetic stimulation (TMS) to measure brain signals.
Austin, TexasAges 18 years+ - NCT06362382Recruiting
Home rehab via smartphone for pulmonary hypertension
This study tests whether a home-based exercise program, guided by a smartphone app, can improve your daily life and heart function if you have pulmonary hypertension. You will use a wearable device to track your activity and receive remote support from a medical team.
Beijing, Beijing MunicipalityAges 18–60 - NCT06681428Recruiting
Amniotic tissue treatment for diabetic foot ulcers
This trial tests whether an amniotic tissue treatment can help heal chronic diabetic foot ulcers that haven't improved with standard care. It focuses on a single ulcer below the ankle that has been present for more than 4 weeks but less than a year.
Fresno, CaliforniaAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.