Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT05303649Recruiting
Theta burst brain stimulation for language problems after stroke
This study tests whether a type of brain stimulation guided by a brain scan (MRI) can improve speech and language (“aphasia”) after a stroke. It may help people who have trouble producing speech but can still understand others’ words.
Warsaw, Masovian VoivodeshipAges 18–75 - NCT05303896Recruiting
Study changes in remodeling heart tissue before transplant
This study looks at how the heart’s structure changes (“remodeling”) in people with heart failure who are being considered for a heart transplant. It may help doctors better understand what is happening in the failing heart and how to treat it.
Oslo, OsloAges 18–100 - NCT05305482Recruiting
Compare two stents after heart attack treatment
This trial compares two types of stents that release medicine to help keep arteries open after an acute coronary syndrome event (often called a heart attack or unstable angina). It tests whether the standard short course of two blood-thinning medicines for one month is enough, and which stent strategy works best.
SeoulAges 19 years+ - NCT05305911RecruitingPhase 2
SGLT2 drug after first heart attack to reduce heart damage
This Phase 2 trial tests whether an SGLT2 medicine started after a first STEMI heart attack can reduce ongoing heart muscle injury and scarring. It may help people who, based on heart imaging, have larger infarcts and ongoing microvascular damage.
Minneapolis, MinnesotaAges 18–75 - NCT05306834Recruiting
Study to slow memory decline by targeting hidden small brain vessel disease
This trial looks at how to slow cognitive decline and early dementia in people with a specific kind of “silent” blood vessel damage in the brain seen on scans. It may help identify whether targeting this hidden condition can protect thinking and memory over time.
BordeauxAges 60–88 - NCT05308888RecruitingPhase 2
PET scan study of heart inflammation after aortic valve replacement
This Phase 2 trial uses a PET scan to study how local inflammation inside the heart affects the heart’s electrical wiring after a minimally invasive aortic valve procedure. The results may help doctors better predict or prevent rhythm and conduction problems after treatment.
BrestAges 18 years+ - NCT05309343Recruiting
Traditional Chinese medicine study for heart disease patients
This study follows people who are being admitted for heart and blood vessel conditions and records their standard (Western) heart diagnoses. The goal is to describe how traditional Chinese medicine is used for these conditions and what diagnoses the people have.
TianjinAges Any age - NCT05309460RecruitingPhase 4
Labetalol or nifedipine to treat postpartum high blood pressure
This study compares two common blood pressure medicines—labetalol and nifedipine—to control high blood pressure after childbirth. It may help you and your care team find the safest way to bring your blood pressure back to normal after delivery.
Omaha, NebraskaAges 19 years+ - NCT05309707Recruiting
Branched stents for certain aortic arch problems
This study looks at using special branched stent-grafts to treat problems in the aortic arch (such as aneurysm or certain tears). It focuses on how well this approach works and how patients do over follow-up visits.
MadridAges 18–90 - NCT05309850Recruiting
Lifestyle tool for preventing diabetes risk
This study tests a lifestyle “tool” to help people reduce their risk of developing diabetes. It is for adults over 35 who do not have certain types of diabetes already.
MalmöAges 35 years+ - NCT05309876Recruiting
Lifestyle tool after a recent heart attack
This study looks at whether a lifestyle coaching tool (used on a phone or computer) can help prevent another heart problem after a recent heart attack. It may help you improve habits like activity, diet, and risk management during follow-up.
MalmöAges 35–80 - NCT05311137Recruiting
Closed-loop monitoring for atrial fibrillation
This study tests a “closed-loop” approach to treating atrial fibrillation, meaning the care plan may adjust based on how you’re doing. It may help improve how heart rhythm problems are managed over time.
Shanghai, Shanghai MunicipalityAges 18–100 - NCT05312255Recruiting
Non-drug help to improve quality of life in myeloma
This study tests non-chemotherapy supports meant to improve quality of life and immune health for people with multiple myeloma (or related conditions). Depending on the group, it may involve activities, nutrition, and/or a medication like a beta blocker.
Buffalo, New YorkAges 18 years+ - NCT05312164Recruiting
Study collects heart procedure measurements for coronary artery disease
This study helps collect measurement data during a heart catheter procedure when coronary disease is suspected. You may be eligible if you’re having a catheter-based evaluation and doctors plan to assess blood flow to determine how severe a new heart blockage is.
Palo Alto, CaliforniaAges 18 years+ - NCT05313165Recruiting
Stent procedure for poor blood flow in the leg ulcers and gangrene
This trial tests a new minimally invasive procedure (placing a small stent) to improve blood flow to a severely threatened foot or lower leg. It may help people whose ulcers or gangrene are not treatable with standard bypass or other surgeries.
La Jolla, CaliforniaAges 18–95 - NCT05312892RecruitingPhase 1/Phase 2
Study for weight-related hormone signals in people with high blood pressure
This early-phase study looks at how the body’s “fight-or-flight” signals may be involved in weight gain (obesity) and high blood pressure. It may help researchers understand the biology and guide future treatments.
Nashville, TennesseeAges 18–65 - NCT05313620RecruitingPhase 4
Tofacitinib effect on clotting tests in ulcerative colitis
This study looks at how tofacitinib (and related medicines) may affect clotting and blood-platelet function, and whether this could relate to blood clot risk. It includes detailed blood and stool/colonoscopy-related testing in adults with ulcerative colitis and in some people without it.
Madrid, MadridAges 18 years+ - NCT05315141Recruiting
Study of AAV in people with ANCA-associated vasculitis
This study follows people with ANCA-associated vasculitis to better understand the treatment using AAV. Your participation would mainly involve agreeing to be in the study and meeting the study’s disease criteria.
Changsha, HunanAges Any age - NCT05319106Recruiting
Cord blood stem cell treatment for leg venous ulcers
This trial tests human umbilical cord tissue stem cells to help heal venous leg ulcers that have lasted at least one month. It’s for adults who meet specific wound size/depth and health criteria and are willing to follow study visits.
Chongqing, Chongqing MunicipalityAges 18–70 - NCT05320263Recruiting
Thrombectomy timing: aspiration tube vs stent for basilar stroke
This trial compares two ways to remove a blockage in the brain’s basilar artery: suction (aspiration) versus a retriever stent. It may help doctors learn which approach works better for restoring blood flow in acute stroke patients.
BordeauxAges 18 years+ - NCT05320926Recruiting
Clopidogrel vs aspirin after heart stent treatment
This trial compares two blood-thinning medicines—clopidogrel and aspirin—after you have finished a short period of dual therapy following a special type of drug-eluting heart stent. It may help find which medicine works better and is safer for preventing future heart problems.
SeoulAges 19–84 - NCT05321459Recruiting
Testing outcome prediction in comatose patients after cardiac arrest
This study looks at tests that may help predict outcomes in people who remain in a coma 3 to 7 days after surviving a cardiac arrest. It may help doctors better estimate recovery and guide care decisions.
BobignyAges 18 years+ - NCT05321368Recruiting
Program to help control blood pressure and support health equity
This study tests a program that combines clinic care, community support, and phone-based monitoring to help people better manage blood pressure and related health problems. It aims to reduce health differences between groups that have been affected more by preventable disease.
Washington D.C., District of ColumbiaAges 18 years+ - NCT05322837Recruiting
Tracking arm nerve and strength recovery after first stroke
This study follows how stroke survivors’ arm feeling (sensory) and movement (motor) recover over time. It may help clinicians better understand recovery patterns in Asian patients and improve rehabilitation support.
SingaporeAges 21–90
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.