Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT05283603Recruiting
Registry study for people with left bundle branch block
This is an observational registry that collects health information from people who have a heart rhythm pattern called left bundle branch block. It may help doctors better understand causes, outcomes, and care needs for people with this ECG finding.
SassariAges 18 years+ - NCT05286710Recruiting
Thrombectomy treatment for new blood clots in the leg
This trial studies a procedure to remove an acute deep vein blood clot in the leg. It may help restore blood flow faster than standard treatment for certain clot locations.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT05287841Recruiting
Battten graft during septum and turbinate surgery
This study tests whether adding a “batten graft” during septoplasty and turbinate reduction improves nasal breathing and nasal airflow. It aims to see if the graft helps when breathing blockage is mainly from the septum, enlarged turbinates, and the outside nasal valve collapsing.
Poplar Bluff, MissouriAges 18 years+ - NCT05287750Recruiting
Brain disease study using 7.0T brain MRI scans
This study looks at people with brain conditions using a very strong MRI scanner (7.0T). It may help doctors understand brain diseases better and improve how scans are used, but you must be able to safely have the MRI (and possibly contrast dye).
BeijingAges 18–80 - NCT05288894Recruiting
Italian registry for people with repaired Tetralogy of Fallot
This trial is a registry that collects information about people who have had Tetralogy of Fallot (TOF) repaired. It may help doctors better understand long-term outcomes and improve future care.
Ancona, The MarchesAges 10 years+ - NCT05292209RecruitingPhase 2
RiLuzole pill to reduce atrial fibrillation on heart monitoring
This Phase 2 study tests whether riLuzole can reduce episodes of atrial fibrillation (an irregular heart rhythm) around the time of planned cardioversion. Doctors will monitor your heart using a Holter monitor to count and compare rhythm episodes.
Salt Lake City, UtahAges 18 years+ - NCT05292651Recruiting
Stent placement strategy study for blocked heart arteries
This study compares how best to place a coronary stent (a small tube to keep an artery open) using modern techniques. It may help improve how safely and effectively stents are delivered in people with certain types of narrowed heart arteries.
DordrechtAges 18–100 - NCT05292716Recruiting
MitraClip for advanced heart failure with leaky mitral valve
This trial studies whether the MitraClip procedure can improve outcomes for people with advanced heart failure caused by significant leakage of the mitral valve. It focuses on people who still have severe symptoms and poor quality of life despite the best available heart medications.
Brescia, LombardyAges 18–90 - NCT05293080RecruitingPhase 3
Early heart rhythm treatment to help prevent stroke
This trial tests an early treatment approach for people who had a recent ischemic stroke (a stroke caused by a blocked blood vessel) and have an irregular heart rhythm called atrial fibrillation (AF). It aims to lower the chance of having another stroke by treating AF as early as possible after the stroke.
HamburgAges 18 years+ - NCT05293756Recruiting
Helping African American adults take blood pressure medicines consistently
This study tests whether a technology-based program (like a smartphone app or videos) can help you take your blood pressure medicines more reliably and improve blood pressure control. It mainly targets adults who need help staying on a multi-drug treatment plan.
Cleveland, OhioAges 50 years+ - NCT05294055RecruitingPhase 2
Mecapegfilgrastim to help collect stem cells for transplant
This Phase 2 study tests mecapegfilgrastim with chemotherapy to help your body collect enough peripheral blood stem cells for an autologous transplant (using your own cells). It’s for people with multiple myeloma or certain lymphomas who have already had some response to treatment.
Hefei, AnhuiAges 18–65 - NCT05294731RecruitingPhase 1/Phase 2
Study drug for certain B-cell cancers in Chinese participants
This early-stage study tests a new medicine (BGB-16673) that targets B-cell cancer cells in people with specific lymphoma or related blood cancers. It aims to see how well the drug can control the cancer and what side effects it causes, especially in Chinese participants.
Bengbu, AnhuiAges 18 years+ - NCT05295810Recruiting
Breathing test for people with low blood pressure on standing
This study checks how your body controls breathing and heart rate when you stand up, especially if you get dizzy from low blood pressure. It may help researchers understand what causes symptoms and how to improve testing for people with this condition.
Calgary, AlbertaAges 18–100 - NCT05295862Recruiting
Stroke registry for adults after acute stroke
This study enrolls adults who are admitted to the hospital for a sudden (acute) stroke. It mainly collects information about your care and recovery to help improve stroke treatment in the future.
Giessen, HesseAges 18 years+ - NCT05296408Recruiting
Arm exoskeleton rehab for chronic stroke weakness
This trial tests a wearable arm exoskeleton that uses your muscle signals to help rehab a weak arm after stroke. It may help improve arm movement by pairing training with this device, but you must meet specific movement, skin, and scan-safety requirements.
Cleveland, OhioAges 18–89 - NCT05296954Recruiting
Mapping the heart’s pathways in certain fast rhythms
This study uses a high-resolution heart mapping system to locate where certain fast, re-entrant heart rhythms start and travel. It may help doctors better target treatments, especially when the rhythm comes from within the heart’s electrical “node” area.
ToulouseAges 18 years+ - NCT05298436Recruiting
South London stroke registry using health data
This study collects information about people who have had a stroke to learn how to improve care and support. It mainly uses existing medical and health records rather than testing a new medicine.
LondonAges 18 years+ - NCT05298124Recruiting
Repairing a leaking mitral valve in severe heart shock
This trial tests a catheter-based procedure to repair a leaking mitral valve in people who are in severe heart shock and need medication support. The goal is to reduce the valve leak and see if it helps patients stabilize and recover.
Rochester, MinnesotaAges 18 years+ - NCT05297708Recruiting
Blood pressure monitoring at home, office, and with a 24-hour device
This study compares blood pressure readings taken at home, in the doctor's office, and over a full 24-hour period using a portable monitor. It may help understand the best way to track blood pressure in children and teens with slightly high blood pressure.
Cincinnati, OhioAges 6–19 - NCT05298748Recruiting
Audio recordings to help breathing control mature in preterm babies
This trial studies whether listening to special “womb” sounds can help a preterm baby’s breathing control develop as they grow. It may help babies who are already breathing on their own (with low or no extra oxygen support).
Cleveland, OhioAges 1 week–1 month - NCT05299424RecruitingPhase 1/Phase 2
CM336 for multiple myeloma after prior treatments
This trial tests CM336, a new medicine, in people with multiple myeloma that has returned (relapsed) or not responded (refractory) to standard treatments. It may help by trying a different approach when other key medicines have already been tried.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05300997Recruiting
Test blood and antibody markers for suspected acute stroke
This study looks at blood tests to find signs of immune activity after a suspected stroke. It may help doctors diagnose stroke faster and better understand what is happening in the body soon after symptoms start.
Hong KongAges 18–100 - NCT05301348Recruiting
Checking for blood clots in people with recent clot symptoms
This study tests a way to detect circulating blood clots in people who have a current or recent blood clot in the veins or arteries, or an acute stroke. It may help doctors find clots more quickly by improving how clots are detected in the bloodstream.
Little Rock, ArkansasAges 18 years+ - NCT05302271RecruitingPhase 1
Testing gene therapy for Friedreich’s ataxia heart disease
This Phase 1 trial tests an AAV gene therapy that aims to improve heart problems caused by Friedreich’s ataxia. You may be eligible if you have genetically confirmed Friedreich’s ataxia with measurable heart weakening but still enough heart function to safely receive treatment.
New York, New YorkAges 12–50
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.