Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,626 recruiting studies in this area right now.
By phase
- Not applicable7,647
- Phase 4471
- Phase 2470
- Phase 3439
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke798
- Heart Failure538
- Hypertension390
- Cardiovascular Diseases374
- Coronary Artery Disease361
- Multiple Myeloma328
- Atrial Fibrillation258
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke138
- Pulmonary Hypertension105
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Acute Coronary Syndrome74
- Obesity74
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine57
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona183
- Massachusetts174
- New York165
- Florida141
- Texas122
- Maryland119
- Minnesota118
- Illinois111
Recruiting studies9,626 total
- NCT06224660RecruitingPhase 1
Gene therapy for heart problems in Duchenne muscular dystrophy
This trial tests an experimental therapy for heart weakness caused by Duchenne muscular dystrophy. It aims to improve how heart cells handle calcium to protect heart function.
Kansas City, KansasAges 18 years+ - NCT06409754Recruiting
Brain-computer interface for arm recovery after stroke
This trial tests a brain-computer interface system that helps move your arm using electrical stimulation. It is for people who have had a stroke at least 6 months ago and have lasting weakness in one arm.
Mexico City, Mexico CityAges 18 years+ - NCT07360925Recruiting
Fat around heart arteries in transplant patients
This study looks at a type of fat around the heart's arteries in people who need a heart transplant. It may help doctors understand how fat affects heart disease.
PragueAges 30–90 - NCT06652425Recruiting
How cold affects the heart and blood vessels
This study looks at how brief cold exposure affects the heart and blood vessels in healthy adults. It may help us understand the body's response to cold and its potential health impacts.
Shanghai, Shanghai MunicipalityAges 18–30 - NCT07360158Recruiting
Studying a new implantable heart device (ICD) for heart patients
This study is testing a new type of implantable cardioverter-defibrillator (ICD) or cardiac resynchronization therapy defibrillator (CRT-D) called the CorSky Family. The goal is to see how well it works for people who need a device to help their heart pump properly and prevent dangerous rhythms.
Graz, StyriaAges 18–99 - NCT07359768Recruiting
Testing a noninvasive device for heart disease risk
This trial uses a noninvasive device to examine small blood vessels in people at high risk for heart disease. It may help doctors better understand who needs preventive care.
Stockholm, DanderydAges Any age - NCT07357285Recruiting
Stroke treatment trial for smaller vessel blockages
This trial tests a new catheter device to remove blood clots from smaller brain arteries in people having a stroke. It aims to see if the device is safe and effective for patients treated within 24 hours of symptoms starting.
BonnAges 18 years+ - NCT07361289Recruiting
Mavacamten for obstructive hypertrophic cardiomyopathy in China
This study looks at how well mavacamten works in real life for adults with obstructive hypertrophic cardiomyopathy, a condition where the heart muscle is thickened and blocks blood flow. It may help improve symptoms like shortness of breath or chest pain.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07361445Recruiting
Study of a device to help access the heart during ablation
This trial tests a new device to help doctors safely enter the left side of your heart during a procedure called ablation. If you are already scheduled for an ablation or a combined ablation and left atrial appendage closure, this study may be an option.
Jonesboro, ArkansasAges 18 years+ - NCT07361302RecruitingPhase 3
Tenecteplase for stroke after 4.5 hours
This trial tests a clot-dissolving medicine called tenecteplase for people who had a stroke more than 4.5 hours ago. It may help you recover if given later than usual.
Buenos AiresAges 18 years+ - NCT07354841Recruiting
Testing safety of heart-lung machine tubes
This study tests two types of tubes used during heart surgery to connect you to a heart-lung machine. It aims to see if they work safely and effectively.
Bari, BAAges 18 years+ - NCT07360418Recruiting
Follow-up study for healed diabetic foot ulcers
This trial checks if diabetic foot ulcers that healed during an earlier study stay closed over time. You can join only if your ulcer fully healed in that previous trial.
Clinton Township, MichiganAges 18 years+ - NCT07361276Recruiting
Observational study on high blood pressure treatment in public clinics
This study looks at how doctors treat high blood pressure in public health clinics. By reviewing medical records, researchers hope to understand what treatments are used and how well they work.
FlorianópolisAges 18 years+ - NCT07352800RecruitingPhase 2
Study of APAC for peripheral artery disease and severe leg ischemia
This trial tests a new drug called APAC to see if it safely prevents blood clots and improves blood flow in people with narrowed leg arteries. It may help those with severe symptoms like pain at rest or non-healing wounds, or those with claudication (leg pain when walking).
HelsinkiAges Up to 85 years - NCT07358078Recruiting
Long-term study of ATTR-CM patients on vutrisiran or other approved therapies
This study observes people with ATTR-CM (a heart condition caused by a protein called transthyretin) who are starting treatment with vutrisiran or another approved therapy. It aims to understand how the disease progresses and how treatments work in real life.
Tucson, ArizonaAges 18 years+ - NCT07357428Recruiting
Brain-computer implant study for severe paralysis or speech loss
This study tests a brain-computer implant that might help people with severe paralysis or speech loss control a computer with their thoughts. It is for people who have trouble moving and speaking due to a progressive disease or injury.
Sacramento, CaliforniaAges 22–75 - NCT07353710Recruiting
Testing a new imaging system during heart ablation
This study tests a new imaging system (CHORUS IDx) that uses 2D ultrasound pictures to help doctors during a heart ablation procedure. It may help guide the procedure more safely.
MerewetherAges 18 years+ - NCT07358793Recruiting
Simulation training for emergency teams
This study compares two ways of training emergency teams to handle adult medical emergencies (not from injury). It looks at how well teams work together using a standard approach called A-C-L-S.
Douliu, YunlinAges 18 years+ - NCT07360067Recruiting
Comparing two types of heart pacing for sick sinus syndrome
This study compares two different ways of placing a pacemaker lead to see which one better helps heart function and reduces future heart problems in people with sick sinus syndrome.
Seoul, SeoulAges 19 years+ - NCT07360899Recruiting
Closing the left atrial appendage during heart surgery to prevent stroke
This trial tests if closing the left atrial appendage with a special stitch during planned heart surgery can help prevent strokes in people with atrial fibrillation. If you already need heart surgery, this extra step may reduce your future stroke risk.
Kamenitz, VojvodinaAges 18 years+ - NCT07356778RecruitingPhase 4
Study of sotatercept for Eisenmenger syndrome patients
This trial tests a new drug called sotatercept for people with Eisenmenger syndrome or a related heart defect that hasn't been repaired. It may help if current treatments aren't working well enough.
Fukuoka, Not Required For This CountryAges 18 years+ - NCT07352709Recruiting
Ventilation feedback simulation for EMS crews
This trial tests a simulation tool that gives feedback on ventilation performance. It is designed for currently active EMS professionals to see if the tool improves their skills.
Dallas, TexasAges 18–60 - NCT07359287Recruiting
Study on antibiotic use for respiratory infections
This study tests a program to help doctors prescribe antibiotics more carefully for common respiratory infections like colds, flu, bronchitis, and sinusitis. It may lead to better treatment for you.
CaenAges Any age - NCT07356011Recruiting
Exoskeleton for balance after stroke
This trial tests whether wearing a robotic exoskeleton can help improve balance and reduce falls in people who had a stroke at least 6 months ago and still have leg weakness. It may be a good fit if you are worried about falling and can walk on a treadmill without a cane or walker.
Charleston, South CarolinaAges 21 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,626 recruiting cardiology studies from the U.S. registry right now, out of 14,734 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.