Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,626 recruiting studies in this area right now.
By phase
- Not applicable7,647
- Phase 4471
- Phase 2470
- Phase 3439
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke798
- Heart Failure538
- Hypertension390
- Cardiovascular Diseases374
- Coronary Artery Disease361
- Multiple Myeloma328
- Atrial Fibrillation258
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke138
- Pulmonary Hypertension105
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Acute Coronary Syndrome74
- Obesity74
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine57
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona183
- Massachusetts174
- New York165
- Florida141
- Texas122
- Maryland119
- Minnesota118
- Illinois111
Recruiting studies9,626 total
- NCT07334834Recruiting
Better cholesterol management for people with artery disease
This study tests a team-based approach to help people with artery disease (like heart attacks or leg blockages) get their cholesterol to a healthier level. If your LDL is above 70, you may benefit from extra support to manage your medications.
Aurora, ColoradoAges 18 years+ - NCT07336394Recruiting
Study on rare heart muscle diseases using advanced MRI
This study uses a special heart MRI to better diagnose and understand rare heart muscle diseases. It may help doctors predict risks and make more accurate treatment decisions.
BeijingAges Any age - NCT07335770Enrolling by invitation
Heart MRI for diagnosing and managing heart masses
This trial uses cardiac MRI to better understand heart masses (tumors or clots) and guide treatment decisions. It may help determine what the mass is and how it affects your health.
Ages Any age - NCT06701968Recruiting
Healthy Nordic diet for heart artery health after heart attack
This study tests whether a healthy Nordic diet (like whole grains, berries, fish, and vegetables) can slow down hardening of the arteries in people who have had a heart attack or have stable chest pain. It lasts 18 months and aims to improve heart health.
UppsalaAges 50–80 - NCT06849635Recruiting
Cera ASD closure device long-term follow-up study
This study follows up with patients who already received the Cera ASD occluder device to close a hole in the heart (atrial septal defect). It looks at how well the device is working over time and checks for any late problems.
MyszkówAges Any age - NCT06862700Recruiting
Less vasopressors for heart shock on ECMO
This trial is studying whether using less of the medicines that raise blood pressure (vasopressors) can help people with severe heart failure who are on a heart-lung machine (ECMO) survive. It may answer if a gentler approach is safer.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05353140Recruiting
Left atrial appendage device vs blood thinners after stent
This trial compares a heart device that can help prevent blood clots in the heart (called LAAO) versus long-term blood thinners for people who have atrial fibrillation and recently had a stent placed. It aims to see which approach better prevents stroke and related blood-clot problems while keeping side effects manageable.
Xi'an, ShannxiAges 18 years+ - NCT06860646Recruiting
Heart attack study for adults 75 and older
This trial is for older adults aged 75 and up who have had a heart attack. It aims to study the best care for elderly patients with this condition.
RyazanAges 75 years+ - NCT06862063Recruiting
Genetic study of spontaneous neck artery tears
This study looks at the genes of people who have had a spontaneous tear in a neck artery. It aims to find if there is an underlying genetic cause, which could help guide treatment for you and your family.
Rome, LazioAges 18 years+ - NCT05190718Recruiting
Pharyngeal electrical stimulation for swallowing trouble after brain injury
This trial tests a non-drug therapy that uses gentle electrical stimulation to help people swallow safely when swallowing is affected by certain brain or nerve conditions. If you qualify, you may receive this approach to improve swallowing and reduce choking risk.
Tulln, Low AustriaAges 18 years+ - NCT04178434Recruiting
Online therapy for stress and anxiety after heart pain without blockages
This trial studies whether an internet-based therapy program can reduce stress and anxiety in people who may have heart-related conditions like MINOCA or takotsubo syndrome, but without significant coronary artery blockages. If you fit the mood and heart criteria, the program may help you feel calmer and improve day-to-day wellbeing.
StockholmAges 35–79 - NCT05782010Recruiting
Testing a hemorrhoid device for grade II or III hemorrhoids
This study tests how safe and well a hemorrhoid treatment device (PexyEazy®) works for adults with moderate-to-severe hemorrhoids (grade II–III). You may be a candidate if you fit the hemorrhoid grade and medical safety requirements and can follow the study plan.
FrölundaAges 18–84 - NCT06212193Recruiting
Trillium Stent Graft for Leaky Heart Valve
This trial tests a new stent graft device (Trillium) placed through a vein to help fix a severely leaky tricuspid valve without open-heart surgery. It is for people with severe symptoms who cannot have or have not improved with standard treatments.
Thousand Oaks, CaliforniaAges 18–85 - NCT06601127RecruitingPhase 2
Tiprogrel for recent minor stroke or high-risk TIA
This trial tests a new anti-platelet drug called Tiprogrel to prevent another stroke in people who recently had a minor stroke or a transient ischemic attack (TIA) with certain artery narrowing or plaques. It aims to see if this medicine is safe and works better than current treatments.
Shenyang, LiaoningAges 40 years+ - NCT06660719RecruitingPhase 3
New stroke medicine SP-8203 with clot-busting therapy
This trial tests a new medicine called SP-8203 added to standard clot-busting treatment for people having a moderate to severe stroke. The goal is to see if it helps improve recovery and is safe.
BusanAges 19–85 - NCT06852976RecruitingPhase 2
Gel treatment for diabetic foot ulcers study
This trial tests a new gel (MDI-1228-mesylate) applied to diabetic foot ulcers to see if it helps them heal faster than standard care alone. It is for people who have had a foot ulcer for at least 12 weeks and are already receiving standard treatment.
Durham, North CarolinaAges 18–75 - NCT06842095Recruiting
Stimulation therapy for stroke recovery
This trial tests if a non-invasive brain stimulation technique can improve arm movement recovery after a stroke. It is for people who had a stroke affecting their arm and are at least 3 months past the stroke.
OxfordAges 18 years+ - NCT07330752Recruiting
First test of A3-Shield device for belly artery bulge
This trial tests a new device called the A3-Shield that is placed inside the belly's main artery to support a bulging area (aneurysm) and keep it from growing or bursting. It may be an option for patients whose aneurysm is large enough but not yet causing symptoms.
TashkentAges 18 years+ - NCT07324837RecruitingPhase 3
Study of a clot-busting drug for stroke up to 24 hours later
This trial tests a single dose of a new clot-dissolving medicine for people who had a stroke 4.5 to 24 hours ago. It may help if you cannot have standard treatments like a clot-removal procedure or other clot-busting drugs.
Ryazan, Ryazan OblastAges 18 years+ - NCT07333183RecruitingPhase 2
Mosliciguat plus treprostinil for lung disease with pulmonary hypertension
This trial tests a new medicine called mosliciguat combined with an inhaled treatment (treprostinil) for people who have both scarring lung disease (interstitial lung disease) and high blood pressure in the lungs. It aims to see if this combination can improve how well you feel and function.
Santa Barbara, CaliforniaAges 18–85 - NCT07333547Recruiting
WILLEM AI ECG study for high-risk heart patients
This study is collecting information from people who have had an ECG (a heart test) to see if a special AI program called WILLEM can help doctors find high-risk heart patients. The study looks at your ECG data and health records to improve heart care.
Nashville, TennesseeAges 18 years+ - NCT07330882Enrolling by invitation
Heart health app study for coronary disease
This study tests a smartphone app to help people with coronary heart disease manage their health. You may be eligible if you have been diagnosed with coronary heart disease, can use a smartphone, and have no serious health issues that would limit exercise.
BengbuAges 18–80 - NCT07329842Recruiting
Bed height and CPR quality in pediatric simulation
This trial tests how the height of a hospital bed affects chest compression quality and the physical strain on doctors during CPR on a child-sized manikin. It may help find the optimal bed height to improve CPR effectiveness.
Antalya, AntalyaAges 18 years+ - NCT07326605Enrolling by invitation
Heart MRI study for heart failure with preserved pumping function
This trial uses a special heart MRI to create pressure-volume loops in people with heart failure who have a normal pumping strength (ejection fraction of 50% or higher). It aims to better understand heart function and could help guide future treatments. You may qualify if you have heart failure symptoms and specific heart structure or function changes.
Ages 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,626 recruiting cardiology studies from the U.S. registry right now, out of 14,734 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Mental health
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- Immune system & allergy
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- Skin
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- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
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- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.