Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT05401630Recruiting
Mental stress testing in postmenopausal women with chest pain
This study looks at how your heart reacts to mental stress in postmenopausal women, including those with chest pain and those with or without blocked heart arteries. It uses a special heart scan (MIBG) and stress tasks to understand differences that may help guide future care.
Atlanta, GeorgiaAges 45 years+ - NCT05403151Recruiting
Healthy blood vessel and control study
This study looks at healthy adults and how their blood vessels work. It may help researchers understand normal circulation so they can better compare changes in future conditions.
Bethesda, MarylandAges 18–90 - NCT05405387RecruitingPhase 2
Budesonide to prevent serious diarrhea after stem cell transplant
This Phase 2 study tests whether budesonide can lower the chance of moderate-to-severe diarrhea in people with multiple myeloma who are getting an autologous stem cell transplant. It may help your comfort and reduce complications during the transplant recovery period.
Salt Lake City, UtahAges 18 years+ - NCT05406635Recruiting
Imaging vs blood tests to guide heart-safe HER2 treatment
This trial compares whether special heart imaging or blood tests better helps monitor heart safety while you receive HER2-targeted therapy (like trastuzumab, with or without pertuzumab) plus chemotherapy. It may help doctors catch early heart stress and choose the safest treatment plan for you.
AalborgAges 18–90 - NCT05410925RecruitingPhase 4
Half-dose r-SAK before heart stent procedure for heart attack
This trial tests whether a half-dose medicine called r-SAK given before a primary PCI heart stent procedure improves outcomes and safety in people with a specific type of heart attack. It may help the heart recover better, but it also checks the risk of side effects like bleeding.
Nanjing, JiangsuAges 18–75 - NCT05410457Recruiting
Study different treatments after ischemic stroke
This trial looks at which treatment approach after an ischemic stroke (a stroke caused by a blocked blood vessel) may lead to better outcomes. It may help doctors better choose treatments that improve recovery and prognosis.
Nanjing, JiangsuAges 18 years+ - NCT05411029Recruiting
Study on sleep problems in Somali adults
This study looks at how disrupted sleep shows up in Somali adults without certain health conditions. It may help researchers understand sleep patterns in this community and improve future sleep support.
Rochester, MinnesotaAges 18–70 - NCT05411614Recruiting
Testing two heart procedures for atrial fibrillation in heart failure
This study compares two different ablation procedures (treatments that target heart rhythm triggers) for people with atrial fibrillation and reduced heart pumping. It aims to see which approach works best and is safest for improving your heart rhythm when you also have heart failure.
ChertseyAges 18 years+ - NCT05412927Recruiting
Heart device follow-up study for high-risk heart patients
This study monitors how well the AngelMed Guardian® System works after it has already been implanted. It focuses on people at higher risk of heart events, including those with diabetes or kidney problems.
Glendale, ArizonaAges 21 years+ - NCT05413057Recruiting
Testing blood pressure pills with two or three medicines
This trial studies whether fixed-dose blood pressure medicines—either two drugs (fimasartan + amlodipine) or three drugs (fimasartan + amlodipine + hydrochlorothiazide)—work well and are safe. It may help your care team compare how these combinations control blood pressure and what side effects occur.
SeoulAges 19 years+ - NCT05412862Recruiting
Improving mood after a recent heart event
This study looks at whether increasing positive emotions after an acute heart problem (like a heart attack or unstable angina) can help patients feel and function better. You may be eligible if you had a recent heart event and are not currently getting enough physical activity.
Boston, MassachusettsAges 18–95 - NCT05416385Recruiting
Stress echo scan with special contrast to study carotid plaque
This study uses a heart stress ultrasound test, plus a contrast dye, to look for new blood vessel growth inside carotid plaque (the buildup in neck arteries). It may help doctors better judge the risk of stroke and determine which people need closer care.
Calgary, AlbertaAges 18 years+ - NCT05415332Recruiting
Tracking outcomes for cardiogenic shock in ICU
This study looks at how people with cardiogenic shock (or very low blood pressure from heart causes) do after treatment in a specialized cardiovascular ICU. It also examines whether care by heart critical-care specialists affects outcomes.
SeoulAges 19 years+ - NCT05416879Recruiting
Lifestyle support for women newly diagnosed with heart failure
This study looks at how lifestyle behaviors affect people in the weeks after a new heart failure diagnosis. It may help you learn safer physical activity and understand what supports you while you adjust to treatment.
Newcastle upon TyneAges 18 years+ - NCT05417490Recruiting
Study of why people join PRADO and telemedicine for heart failure
This study looks at what influences whether people with heart failure choose to join PRADO and telemedicine support after a hospital stay. Your answers can help the team understand barriers and improve future participation and care.
MontpellierAges 18 years+ - NCT05421767RecruitingPhase 4
Renal nerve stimulation for hard-to-control high blood pressure
This trial tests whether stimulating nerves around the kidney can lower blood pressure in people whose high blood pressure stays uncontrolled despite treatment. It may help by improving how the kidneys and blood vessels regulate blood pressure.
TaipeiAges 20 years+ - NCT05422027RecruitingPhase 1/Phase 2
Selinexor with VRd for high-risk newly diagnosed myeloma
This early-phase study tests whether selinexor combined with VRd (bortezomib, lenalidomide, and dexamethasone) can improve outcomes for people with high-risk, newly diagnosed multiple myeloma. You may be a candidate if you have certain lab/genetic signs of “high-risk” disease and haven’t had prior myeloma treatment.
Guangzhou, GuangdongAges 18 years+ - NCT05422859Recruiting
Using a mobile app in heart failure care networks
This trial tests whether a mobile and digital app can be used by people with heart failure who receive care in specific clinics in Berlin or Brandenburg. It may help support communication and care by putting information and tools in your phone.
Berlin, DeutschlandAges 18 years+ - NCT05423860Recruiting
HALO prostate study for men with early prostate cancer
This trial studies HALO, a new “human analytics” approach, in men with early-stage prostate cancer. It may help doctors better assess or guide care using MRI and biopsy findings, before or around initial treatment.
Indian Wells, CaliforniaAges 45–90 - NCT05424016Recruiting
Propranolol for brain blood-vessel tumors in VHL
This trial studies whether propranolol, a beta-blocker medicine, can help people with VHL who have non-urgent hemangioblastomas in the brain/spinal cord. It aims to see if the medication is safe and beneficial without needing immediate surgery.
Le Kremlin-BicêtreAges 18 years+ - NCT05424978Recruiting
Standardized green-channel treatment for acute stroke care
This study tests a structured, fast way of treating people who have a new ischemic stroke (a stroke caused by a blocked blood vessel). It may help because it focuses on getting the right stroke treatments quickly and consistently.
Xi'an, ShaanxiAges 18–100 - NCT05425615Recruiting
Testing brain stimulation to improve language after left stroke
This study tests a form of brain stimulation (TMS) in people who had a stroke affecting the left side of the brain. It aims to understand whether stimulation can help with language processing tasks at least a month after stroke.
Milwaukee, WisconsinAges 18–85 - NCT05426408Recruiting
Test study for heart attacks without blocked arteries
This study looks at people who may have MINOCA (heart attack symptoms with no major artery blockage) or takotsubo syndrome (a temporary stress-related heart condition). The goal is to better understand these causes and how they should be diagnosed and treated.
StockholmAges 35–79 - NCT05427786RecruitingPhase 4
Nicotinamide-like heart medicine given during stent helps blood flow
This trial studies whether a medicine (nicorandil) given into a coronary artery during stent procedures can help keep blood flow from getting worse. It may help people having stent placement for coronary artery disease by improving how well blood moves through the treated area.
SeoulAges 19 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Mental health
- Digestive system
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- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
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- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.