Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT06280482RecruitingPhase 1
Nicotinamide Riboside for Moyamoya in Smooth Muscle Dysfunction
This trial tests a vitamin B3 supplement called nicotinamide riboside (NR) to see if it can help people with Smooth Muscle Dysfunction Syndrome (SMDS) who have a specific gene mutation. The goal is to improve blood flow problems in the brain (moyamoya-like disease) caused by the condition.
Houston, TexasAges 1 year+ - NCT06280924Recruiting
Exercise before or after stem cell transplant for multiple myeloma
This study tests whether a 10-week exercise program (prehab) before or after a stem cell transplant can help people with multiple myeloma feel stronger and recover better. You can join whether you are getting a transplant or not, as long as you live in Alberta and have internet access.
Edmonton, AlbertaAges 18 years+ - NCT06281067Recruiting
Personalized medicine for heart muscle bridges
This trial aims to better understand and treat a condition called a myocardial bridge, where a heart artery tunnels through the heart muscle instead of sitting on top. It tests whether a more personalized approach, using special medications during heart catheterization, can improve care for people with symptoms like chest pain or shortness of breath.
Acquaviva delle FontiAges 18–75 - NCT06281665RecruitingPhase 4
Aspirin after preeclampsia: the TAP trial
This trial tests whether taking low-dose aspirin after giving birth can help people who had preeclampsia. It aims to see if aspirin can lower the risk of future heart problems.
Pittsburgh, PennsylvaniaAges 18–55 - NCT06281756RecruitingEarly Phase 1
CBT and Trazodone for Sleep and Blood Pressure in Insomnia
This trial tests whether cognitive behavioral therapy (a type of talk therapy for sleep) and/or the medication trazodone can improve sleep and lower blood pressure in people with chronic insomnia. You must be 18 or older and have ongoing trouble sleeping.
Denver, ColoradoAges 18 years+ - NCT06282939Recruiting
Optima Coil Registry for Brain Aneurysm Treatment
This registry tracks how well the Optima Coil System works to treat brain aneurysms. It is for adults with a berry-shaped aneurysm that hasn't been treated before and is smaller than 24 mm. The goal is to see how safe and effective these coils are in real-world use.
Plano, TexasAges 18 years+ - NCT06282796Recruiting
Early heart risk monitoring for breast cancer chemo
This study tests a method to predict and warn about heart damage from a common type of breast cancer chemotherapy. If you have HER2-positive breast cancer and will receive anthracycline drugs, this trial may help monitor your heart health.
Fuzhou, FujianAges 18–80 - NCT06283069Recruiting
Lifestyle and heart health: an observational study
This study looks at how your daily habits—like what you eat, how much you exercise, and your sleep—relate to your heart health. Researchers will ask you to fill out a questionnaire and collect information from your medical records to learn more.
MilanAges 6 years+ - NCT06283420Recruiting
Metabolic Effects of Starting Heart Failure Therapies
This trial looks at how starting new heart failure treatments affects your body's metabolism. It may be an option if you have stable heart failure and haven't taken certain newer medicines before.
PragueAges 18 years+ - NCT06283758Recruiting
Ultrasound treatment for kidney fat to lower blood pressure
This trial tests a new ultrasound treatment that targets the fat pad around your kidney to lower blood pressure. It might be an option if your blood pressure is still high despite medication and you meet the size requirements for the fat pad.
Nanjing, JiangsuAges 18–65 - NCT06284057Recruiting
Culotte stent technique study for Y-shaped heart blockages
This trial studies two different ways of placing stents in Y-shaped blockages in the heart's arteries. It aims to find which technique works best for people who need two stents in that area.
Legnica, Lower Silesian VoivodeshipAges 18 years+ - NCT06283940Recruiting
Exercise rehab after heart valve replacement
This study tests whether a structured exercise program helps people recover better after a minimally invasive aortic valve replacement, called TAVI. If you have had this procedure, you may join to improve your heart health and daily function.
AlingsåsAges 65 years+ - NCT06283888RecruitingPhase 4
Choosing a blood thinner based on your genes after complex heart treatment
This trial tests whether choosing a blood thinner based on your DNA can prevent more heart problems. If you've had a complex heart procedure, you may be able to get a medication that works best for your body.
Zunyi, GuizhouAges 18–80 - NCT06284395Recruiting
Comparing multiple myeloma treatment plans
This study looks at two different drug combinations for people with multiple myeloma who are eligible for a stem cell transplant. It aims to find which treatment works better.
Mexico City, Mexico CityAges 18–90 - NCT06284343Recruiting
Gynecologic Cancer and Blood Clot Risk Study
This study looks at the risk of blood clots in women with gynecologic cancers who are starting a new line of cancer treatment. It aims to help doctors better predict and prevent blood clots in patients like you.
RomeAges 18 years+ - NCT06284642RecruitingPhase 4
Drain and clot-dissolving medicine for severe aneurysm bleeding
This trial tests whether placing a small drain in the lower back and giving a clot-dissolving medicine (urokinase) into the fluid around the brain can help people recover from a severe bleeding stroke caused by a brain aneurysm. It is for patients who are treated quickly after the bleed.
Hefei, AnhuiAges 18 years+ - NCT06285760Recruiting
Acetazolamide for fluid removal in acute heart failure
This study tests whether adding acetazolamide (a different type of water pill) to your current treatment helps remove extra fluid from your body more effectively when you are in the hospital for heart failure.
MadridAges Any age - NCT06285539RecruitingPhase 2
Testing a drug for rare inflammatory diseases
This trial is testing a new drug (a JAK inhibitor) for people with rare inflammatory diseases like Behçet's, myositis, or IgG4-related disease that hasn't improved with standard treatments. The goal is to see if it can help control symptoms and reduce inflammation.
AmsterdamAges 18–65 - NCT06286358Recruiting
Heart and aorta imaging study for valve disease
This study uses a special recording device to see if heart and aorta problems can be detected earlier. It may help people with aortic valve disease or enlarged aorta decide on treatment.
BrusselsAges 18 years+ - NCT06286423RecruitingPhase 4
Colchicine for acute heart failure with low pumping strength
This trial tests if the anti-inflammatory drug colchicine can help people hospitalized with acute heart failure and a weak heart pump. It may benefit those with elevated inflammation markers.
Charlottesville, VirginiaAges 18 years+ - NCT06286878RecruitingPhase 2/Phase 3
Dapagliflozin after a heart attack: recovery study
This trial tests whether a diabetes drug called dapagliflozin (also used for heart failure) can help people recover better after a recent heart attack. It's for adults who are already on standard blood thinners and have had a heart attack in the past week.
São Paulo, São PauloAges 18 years+ - NCT06286800Recruiting
Personalized brain stimulation for stroke recovery
This study tests a personalized, non-invasive brain stimulation treatment called transcranial direct current stimulation (tDCS) to help improve movement in people who have had a stroke that affects one side of the body. It aims to see if this gentle electrical stimulation can boost recovery of arm and hand function.
Houston, TexasAges 18–80 - NCT06287645Recruiting
Eye photos for diabetes patients
This trial takes colored photos of the back of your eye to help experts identify diabetes-related changes. It may help detect eye problems early in people with diabetes.
KarachiAges 20 years+ - NCT06288204Recruiting
Green Propolis and Royal Jelly for Kidney Health
This trial tests whether a supplement made from green propolis (a natural bee product) and royal jelly can help people with high blood pressure and chronic kidney disease. It aims to see if the supplement can improve kidney health and blood pressure control.
Rio de Janeiro, Rio de JaneiroAges 18–75
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.